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The role of splanchnic vasoconstrictor in decreasing peripheral vasodilatation to reduce ascites formation of liver cirrhosis

232

Med J Indones

Akbar et al.

The Role of Splanchnic Vasoconstrictor in Decreasing Peripheral

Vasodilatation to Reduce Ascites Formation of Liver Cirrhosis

Nurul Akbar*, Soemarnot, Sumedi Sumarsonof , Laurentius Lesmana*, Unggul Budi Husodo*, Ali Sulaiman*,
H.M. Sjaifoellah Noer*

Abstrak
Vasodilatasi periftr menyebabkan pengisian yang relatif kurang pada kompartimen vaskular sehingga mengaktiJkan mekanisme
kompensasi, yang menyebabkan retensi sodium dan asites. Sintetik analog somatostatin adalahvasokonstrtktor, yang menurunkan aliran

darah splnngnik sehingga mengurangi yasodilatasi perifur. Peranan splangnik vasokonstriktor terhadap vasod'ilatasi p,erifer belum
pernah diselidiki. Penelitian ini dilnkut

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