DAMPAK SUPLEMENTASI 1,25-DIHIDROKSIVITAMIN D3 TERHADAP EKSKRESI KALSIUM URIN DAN AKUMULASI KALSIUM TULANG TIKUS WISTAR PANHISTEREKTOMI YANG MENGKONSUMSI TERI TAWAR | Hartiningsih | Jurnal Sain Veteriner 284 142 1 PB

DAMPAK SUPLEMENTASII,2s-DIHIDROKSIVITAMIN D3TERHADAP EKSKRESI KALSIUM
URIN DAN AKUMULASI KALSIUM TULANG TIKUS WISTARPANHISTEREKTOMI YANG
MENGKONSUMSITERI TAWAR

THE IMPACTOF I.25-DIHYDROXYVITAMIND. SUPPLEMENTOF LINSALTEDFEEDON
CALCIUM URINARY EXCRETIONOF PANHISTERECTOMIZEDWISTARRATS

Hartiningsih', Irkham Widiyono', Devita Anggraeni'
'Bagian

llmu Bedah dan Radiologi,Fakultas Kedokteran Hewan, UniversitasGadjah Mada,
Yogyakarta
'Bagian
Ilmu Penyakit Dalam, Fakultas Kedokteran Hewan, Universitas Gadjah Mada,
Yogyakarta
E-mail: hartiningsihS6@yahoo.com

ABSTRACT

The obyectivesof the researchwere to study the impact of 1.25-dihydroxyvitaminD, suplementationon
urinary Ca excretion and Ca accumulation in panhisterectomizedWistar rats fed with unsaltedanchovy.Fifteen

female Wstar rats, 8 weeks of age, were divided into three groups (control, panhisterectomy,and
panhisterectomy*1,25-dihydroxyvitamin
D, supplement) of five each. At 19 weeks of age,they were placed
into individual metabolic cagesfor a balancestudy.From day4 to I I of the balancestudy,every day,the feed left
over,urine, and feceswere collectedand recordedfor Ca analyses.The resultsof the researchshowedthat Ca
ratsconsuming1,25-dihydroxyvitaminD, supplementarenot significantly
comsumptionin panhisterectomized
difTerentfrom the panhisterectomizedrats not consuming 1,25-dihydroxyvitamin D, supplement.The fecal Ca
excretion was significantly higher (P