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Research Article

Analysis olEndostatin Levels in Early Onset Preeclampsia, Late onset
Preeclampsia and normal Pregnancy
Analisis Kadar EndostatinPadaPreeklamsiAwitandini, PreeklamsiAwitanlamhatdanHamil

Normal
Yusrawati, AldinaAyundalnsani, Nuzulialrawati
Department of Obstetrics and Gynecolog,t
Medical Faculty of Andalas Universityt'
Dr. lv,[. Djamil Hospital
Padang
Abstrak

Abstract

Tujuan:Tujuan

Objective: The purpose of this research is to
analyzethe difference between the mean serum levels
of endostatinin early onset preeclampsia (EOPE), late
onset preeclampsia (LOPE) and normal pregnancy.

Method:This research design was an

analytic cross-sec{ional observation on 80 pregnant


women with EOPE, LOPE and normal pregnancy with

matched gestational age

in M.

Djamil hospital,

Reksodiwiryo hospital, Bhayangkara hospital, Rasidin

Padang hospital, and Anak

Air of Public

Service,

fromJuly to November 2015. Samples were selected
based on consecutive sampling. Blood was collec{ed


pe neliti ani n i ad a I a h me n g a n a I i s i s kad a rc nd o stati n a nta ru

(PEAD),
preeklamsiawitandini
Metode:
sectionafterhadap 80 ibuhamil (PEAD, PEAL
normal
sertahamil
denganusiakehamilansamadengankelompok PEnormal untukkalompok PEAD dan normal

preeklamsiawitanlambat (PEAL) danhamil normal.
Desainpenelitianadalahcrcss

untukkelompok PEAL)
Tingkat

llldr.

di


RSUPdr.

M, Diamit, RS.

Reksodiwiryo, RS. Bhayangkan, RSUD.

intravenously, centrifuged and endostatinserum
measured by ELISA method in the Laboratory of

Air Padang, JuliNovember 2A15. Sampelbedasarkanconsecutive
sampling. funh intavenasampel, disentrifuge,

independent for mean difference, using SPSS.

di LabontoiumBiomedik FK- UNAND. Uiinormalitas
data dengan Shapiro Wlk, bedarentadenganuii t

Biomedical Faculty of Medicine Andalas University.
Normality test data with Shapiro-Wilk, unpaired t-test
Result: The mean levels of endostatinin the

EOPE group and normal pregnancy group is 125149.3
ng/ml and 90.8*28.3n9/ml (p0.05) and finally in the EOPE

group and LOPE group

is

125t49.3n9/mland

86.2121 .8 ng/ml (p