Candra Cahyaningtyas Giyanto 22010111130090 Lap.KTI BAB VIII

DAFTAR PUSTAKA

1. Vitoratos N, Vrachnis N, Iavazzo C, Kyorgiou M. Preeclampsia: molecular
mechanisms, predisposition, and treatment. Journal of Pregnancy[Internet].
2012

[cited

2014

Nov

18].

Available

from

:

http://dx.doi.org/10.1155/2012/145487.

2. Guerrier G, Oluyide B, Keramarou M, Grais RF. Factors associated with
severe preeclampsiaand eclampsia in Jahun, Nigeria. International Journal of
Women’s Health. 2013; 5; 509-513.
3. Cunningham FG, Levenno KJ, Bloom SL, Hauth JC, Rouse DJ, Spong CY.
Hipertensi dalam kehamilan. In : Pendit BU, Setia R, editor. Obstetri
williams. 23th ed. Jakarta : Penerbit Buku Kedokteran EGC; 2013 : 740-794.
4. Backes CH, Markham K, Moorehead P, Cordero L, Nankervis CA, Giannone
PJ. Maternal preeclampsia and neonatal outcomes. Journal of Pregnancy
[Internet].

2011

[cited

2014

Nov

25].


Available

from

:

http://dx.doi.org/10.1155/2011/214365.
5. Membedah angka kematian ibu : penyebab dan akar masalah tingginya angka
kematian ibu. Konferensi INFID; 2013 November 26-27. Jakarta; 2014.
6. Widiyanto. Kehamilan dengan preeklampsia berat [thesis]. Semarang: Bagian
Obstestri dan Ginekologi Fakultas Kedokteran Universitas Diponegoro; 2005.
7. Manuaba IBG, Manuaba IAC, Manuaba IBGF. Hipertensi dalam kehamilan.
In : Astuti NZ, Purba DI, Handayani S, Damayanti R, editor. Pengantar
kuliah obstetri. Jakarta : Penerbit Buku Kedokteran EGC; 2003.

65

66

8. DeCherney AH, Nathan L. Hypertensive states of pregnancy. In : Current

obstetric and gynecologic diagnosis and treatment. 9 th ed. New York :
McGRAW-HILL Inc; 2003.
9. Canzoneri BJ, Lewis DF, Groome L, Wang Y. Increased neutrophil number
account for leukocytosis in women with preeclampsia. American Journal of
Perinatology. 2011.
10. Gana YY. Hubungan kadar hematokrit dengan derajat preeklampsia.
Surakarta : Fakultas Kedokteran Universitas Sebelas Maret; 2010.
11. Yusrianty D, Lukas E, Tahir M. Kadar serum P38 MAPK, profil darah pada
pasien preeklampsia berat dibandingkan kehamilan normal. JST Kesehatan.
2014; 4(3): 291-298.
12. Adhie RP. Hubungan antara kadar hematokrit dan trombosit maternal
terhadap keluaran perinatal pada eklampsia berat [thesis]. Semarang : Bagian
Obstetri dan Ginekologi Fakultas Kedokteran Universitas Diponegoro; 2004.
13. Kawuryan SL. Pengaruh kadar trombosit, hematokrit, hemoglobin darah dan
protein urin pada ibu preeklampsia/eklampsia terhadap nilai apgar bayi yang
dilahirkan. Jurnal Kedokteran Brawijaya. 2004; 20(2): 78-81.
14. Poon LC, Nicolaides KH. Early prediction of preeclampsia. Obstetrics and
Gynecology International[Internet]. 2014 [cited 2014 Nov 17]. Available
from : http://dx.doi.org/10.1155/2014/297397
15. Moura SAMH, Lopes LM, Murthi P, Costa FS. Prevention of preeclampsia.

Journal of Pregnancy[Internet]. 2012 [cited 2014 Nov 17]. Available from :
http://dx.doi.org/10.1155/2012/435090.

67

16. Angsar MD. Hipertensi dalam kehamilan. In : Saifuddin AB, Rachimhadhi T,
Wiknjosastro GH, editor. Ilmu kebidanan sarwono prawirohardjo. Edisi
keempat. Jakarta : Bina Pustaka Sarwono Prawirohadjo; 2011.
17. Birawa AD, Hadisaputro H, Hadijono S. Kadar d-dimer pada ibu hamil
dengan preeklampsia berat dan normotensi di rsup dr. kariadi. Majalah
Obstetri Ginekologi Indonesia. 2009; 33(2): 65-78.
18. Diagnosis and management of preeclampsia and eclampsia. ACOC Practice
Bulletin: Clinical Management Guideline for Obstetrician-Gynecologists.
2002; 33.
19. Vanderlelie J. Placental oxidative stress in preeclampsia[thesis]. Brisbane:
Griffith University; 2005.
20. Powe CE, Levine RJ, Karumanchi A. Preeclampsia, a disease of the maternal
endothelium : the role of antiangiogenic factors and implications for later
cardiovascular disease. American Heart Association Journals. 2014.
21. Indrianto A, Hadisaputro H. Preeklampsia berat di RS Dr. Kariadi periode 1

januari 2004 – 31 desember 2004[thesis]. Semarang: Bagian Obstestri dan
Ginekologi Fakultas Kedokteran Universitas Diponegoro; 2009.
22. Nugroho T. Patologi kebidanan. Yogyakarta: Nuha Medika; 2012: 1-12.
23. Nankali A, Malek-khosravi S, Zangeneh M, Rezaei M, Hemati Z, Kohzadi
M. Maternal complication associated with severe preeclampsia. The Journal
of Obstetrics and Gynecology of India. 2013; 63(2) : 112-115.

68

24. Eiland E, Nzerue C, Faulkner M. Preeclampsia 2012. Journal of
Pregnancy[internet].

2012[cited

2015

Jan

19].


Availabel

from:

http://dx.doi.org/10.1155/2012/586578.
25. Sacher RA, McPherson RA. Widmann’s clinical interpretation of laboratory
test. In : Brahm U, Wulandari D, Hartanto H. Tinjauan klinis hasil
pemeriksaan laboratorium. 11th ed. Jakarta : Penerbit Buku Kedokteran EGC;
2004 : 21-66.
26. Tarwoto,

Watonah.

Keperawatan

medikal

bedah:

gangguan


sistem

hematologi. Jakarta : Trans Info Media; 2008: 9-29.
27. Gandasoebrata R. Penuntun laboratorium klinik. Jakarta : Dian Rakyat; 2007:
11-14.
28. Sutedjo AY. Buku saku mengenal penyakit melalui hasil pemeriksaan
laboratorium. Yogyakarta : Penerbit Amara Books; 2009: 17-35.
29. EffendiZ.

Peranan

tubuh[internet].

leukosit

2003[cited

sebagai


anti

inflamasi

alergik

dalam

2015

Jan

31].

Availabel

from:

library.usu.ac.id/download/fk/histologi-zukesti2.pdf.
30. Mudita IB. Sel darah putih: gangguan fungsi granulosit dan granulopoiesis. In

: Permono HB, Sutaryo, Ugrasena IGD, Windiastuti E, Abdulsalam M. Buku
ajar hematologi-onkologi anak. Jakarta : Badan Penerbit IDAI, 2012: 101132.
31. Kee JL. Laboratory and diagnostic tests with nursing implication. In :
Kurnianingsih S, Widyastuti P, Cahyaningrum R, Rahayu S. Pedoman

69

pemeriksaan laboratorium dan diagnostik. 6th ed. Jakarta: Penerbit Buku
Kedokteran EGC; 2003: 479-482.
32. Onisai M, Vladareanu A, Bumbea H, Ciorascu M, Pop C, Andrei C, et al. A
study of hematologycal picture and of platelet function in preeclampsia.
Maedica : A Journal of Clinical Medicine. 2009; 4(4): 327-337.
33. Sabatier F, Bretelle F, d’Ercole C, Boubli L, Sampol J, Dignat-George F.
Neutrophil activation in preeclampsia and isolated intrauterine growth
restriction. American Journals of Obstetric and Gynecology. 2000; 183(6) :
1558-1563.
34. Mihu D, Sabau L, Costin N, Ciortea R, Oancea M, Malutan A. Evaluation of
leukocytes and neutrophils, markers of inflammatory syndrome in
preeclampsia. Applied Medical Informatics. 2010; 27(3) : 15-22.
35. Raras AA. Pengaruh preeklampsia berat pada kehamilan terhadap keluaran

maternal dan perinatal di RSUP Dr. Kariadi tahun 2010. Semarang : Fakultas
Kedokteran Universitas Diponegoro; 2011.
36. Konimusliha P. Hubungan antara frekuensi pelayanan antenatal dengan
kejadian preeklampsia berat : studi kasus di RSUP Dr. Kariadi tahun 2010.
Semarang : Fakultas Kedokteran Universitas Diponegoro; 2011.
37. Kuriakose P. Anemia: an approach to evaluation, 2014. CHRISMED Journal
of Health and Research [internet]. 2015; 2(2) : 95-99 [cited 17 Jun 2015].
Availabel

from

:

http://www.cjhr.org/article.asp?issn=2348-

3334;year=2015;volume=2;issue=2;spage=95;epage=99;aulast=Kuriakose

70

38. Monteiro G, Subbalakshmi, Pai SR. Revelance of measurement of

hematological parameters in subjects with pregnancy induced hypertention.
Nitte University Journal of Health Science. 2014; 4(1) : 15-20.
39. Yang SW, Cho SH, Kwon HS, Sohn IS, Hwang HS. Significance of the
platelet distribution width as a severity marker for the development of
preeclampsia.

European Journal of Obstetrics

& Gynecology and

Reproductive Biology. 2014; 175 : 107-111.
40. Selamat, Aditiawarman. Clinical and laboratory profiles relationships of
preeclampsia-eclampsia patients with maternal mortality in Dr. Soetomo
hospital, Surabaya. Majalah Obstetri & Ginekologi. 2012; 20 (1) : 35-39.
41. Jwa SC, Fujiwara T, Yamanobe Y, Kozuka K, Sago H.Changes in maternal
hemoglobin during pregnancy and birth outcomes. BMC Pregnancy and
Childbirth. 2015; 15 : 80.

71
Lampiran 1. Ethical Clearance

72
Lampiran 2. SuratIjinPenelitian

73

Lampiran 3. Hasil Output SPSS
Deskripsi Usia Pasien Preeklampsia
Statistic
Mean

29,05

95% Confidence Interval for

Lower Bound

27,52

Mean

Upper Bound

30,58

5% Trimmed Mean

28,91

Median

28,00

Variance
Usia

Std. Error
,770

50,379

Std. Deviation

7,098

Minimum

16

Maximum

48

Range

32

Interquartile Range

12

Skewness
Kurtosis

,253

,261

-,718

,517

Deskripsi Usia Kelompok Kontrol
Statistic
Mean

27,88

95% Confidence Interval for

Lower Bound

26,57

Mean

Upper Bound

29,19

5% Trimmed Mean

27,78

Median

28,00

Variance
Usia

Std. Error

Std. Deviation

36,819
6,068

Minimum

15

Maximum

47

Range

32

Interquartile Range

,658

8

Skewness

,251

,261

Kurtosis

,110

,517

74

Frekuensi Usia Preeklampsia Ringan
Frequency

Valid

Percent

Valid Percent

Cumulative Percent

35 tahun
Total

3

23,1

23,1

13

100,0

100,0

Frekuensi Usia Preeklampsia Berat
Frequency
35 tahun

15

26,8

26,8

100,0

Total

56

100,0

100,0

Frekuensi Usia Eklampsia
Frequency
35 tahun
Total

Percent

Valid Percent

Cumulative Percent

2

12,5

12,5

12,5

12

75,0

75,0

87,5

2

12,5

12,5

100,0

16

100,0

100,0

Frekuensi Usia Kelompok Kontrol
Frequency

Valid

Percent

Valid Percent

Cumulative
Percent

35 tahun

66

77,6

77,6

100,0

Total

85

100,0

100,0

Frekuensi Alamat Preeklampsia Ringan
Frequency
Semarang
Valid

Luar Semarang
Total

12

Percent

Valid Percent

92,3

Cumulative
Percent

92,3

92,3
100,0

1

7,7

7,7

13

100,0

100,0

Frekuensi Alamat Preeklampsia Berat
Frequency

Valid

Semarang

33

Luar Semarang

23

Total

56

Percent
58,9

Valid Percent

Cumulative
Percent

58,9

58,9

41,1

41,1

100,0

100,0

100,0

75

Frekuensi Alamat Eklampsia
Frequency
Semarang
Valid

Percent

Valid Percent

Cumulative
Percent

4

25,0

25,0

25,0

Luar Semarang

12

75,0

75,0

100,0

Total

16

100,0

100,0

Frekuensi Alamat Kelompok Kontrol
Frequency

Valid

Semarang

68

Luar Semarang

17

Total

85

Percent

Valid Percent

80,0

Cumulative
Percent

80,0

80,0

20,0

20,0

100,0

100,0

100,0

Frekuensi Tingkat Pendidikan Preeklampsia Ringan
Frequency
Dasar
Valid

4

Menengah
Total

Percent

Valid Percent

30,8

Cumulative
Percent

30,8

30,8
100,0

9

69,2

69,2

13

100,0

100,0

FrekuensiTingkat Pendidikan Preeklampsia Berat
Frequency
Tidak Sekolah
Valid

Percent

Valid Percent

Cumulative
Percent

3

5,4

5,4

5,4

Dasar

22

39,3

39,3

44,6

Menengah

26

46,4

46,4

91,1

Tinggi

5

8,9

8,9

100,0

Total

56

100,0

100,0

FrekuensiTingkat Pendidikan Eklampsia
Frequency

Valid

Percent

Valid Percent

Cumulative
Percent

Tidak Sekolah

2

12,5

12,5

12,5

Dasar

5

31,3

31,3

43,8
100,0

Menengah
Total

9

56,3

56,3

16

100,0

100,0

76

FrekuensiTingkat Pendidikan Kelompok Kontrol
Frequency

Valid

Percent

Valid Percent

Cumulative
Percent

Dasar

17

20,0

20,0

20,0

Menengah

43

50,6

50,6

70,6

Tinggi

25

29,4

29,4

100,0

Total

85

100,0

100,0

FrekuensiStatus Pekerjaan Preeklampsia Ringan
Frequency
Bekerja
Valid

Percent

Valid Percent

Cumulative
Percent

1

7,7

7,7

7,7

Tidak Bekerja

12

92,3

92,3

100,0

Total

13

100,0

100,0

FrekuensiStatus Pekerjaan Preeklampsia Berat
Frequency

Valid

Percent

Valid Percent

Cumulative
Percent

Bekerja

13

23,2

23,2

23,2

Tidak Bekerja

43

76,8

76,8

100,0

Total

56

100,0

100,0

FrekuensiStatus Pekerjaan Eklampsia
Frequency
Bekerja
Valid

Percent

2

12,5

Valid Percent

Cumulative
Percent

12,5

12,5
100,0

Tidak Bekerja

14

87,5

87,5

Total

16

100,0

100,0

FrekuensiStatus Pekerjaan Kelompok Kontrol
Frequency

Valid

Percent

Valid Percent

Bekerja
Tidak Bekerja

23
62

27,1
72,9

27,1
72,9

Total

85

100,0

100,0

Cumulative
Percent
27,1
100,0

FrekuensiGravida Preeklampsia Ringan
Frequency

Valid

Percent

Valid Percent

Cumulative
Percent

Primigravida

6

46,2

46,2

46,2

Multigravida

7

53,8

53,8

100,0

13

100,0

100,0

Total

77

FrekuensiGravida Preeklampsia Berat
Frequency

Valid

Percent

Valid Percent

Cumulative
Percent

Primigravida

12

21,4

21,4

21,4

Multigravida

41

73,2

73,2

94,6
100,0

Grande Multigravida
Total

3

5,4

5,4

56

100,0

100,0

FrekuensiGravida Eklampsia
Frequency

Valid

Percent

Valid Percent

Cumulative
Percent

Primigravida

11

68,8

68,8

68,8

Multigravida

4

25,0

25,0

93,8
100,0

Grande Multigravida
Total

1

6,3

6,3

16

100,0

100,0

FrekuensiGravida Kelompok Kontrol
Frequency

Valid

Percent

Valid Percent

Cumulative
Percent

Primigravida

29

34,1

34,1

34,1

Multigravida
Grande Multigravida

50
6

58,8
7,1

58,8
7,1

92,9
100,0

Total

85

100,0

100,0

Frekuensi Jumlah Paritas Preeklampsia Ringan
Frequency

Valid

Percent

Valid Percent

Cumulative
Percent

Nulipara

7

53,8

53,8

53,8

Primipara

2

15,4

15,4

69,2
100,0

Multipara
Total

4

30,8

30,8

13

100,0

100,0

Frekuensi Jumlah ParitasPreeklampsia Berat
Frequency

Valid

Percent

Valid Percent

Cumulative
Percent

Nulipara
Primipara

15
19

26,8
33,9

26,8
33,9

26,8
60,7

Multipara

22

39,3

39,3

100,0

Total

56

100,0

100,0

78

Frekuensi Jumlah Paritas Eklampsia
Frequency

Valid

Percent

Valid Percent

Cumulative
Percent

Nullipara

12

75,0

75,0

75,0

Primipara

1

6,3

6,3

81,3
100,0

Multipara
Total

3

18,8

18,8

16

100,0

100,0

Frekuensi Jumlah Paritas Kelompok Kontrol
Frequency

Valid

Percent

Valid Percent

Cumulative
Percent

Nullipara

34

40,0

40,0

40,0

Primipara

28

32,9

32,9

72,9

Multipara

21

24,7

24,7

97,6

2

2,4

2,4

100,0

85

100,0

100,0

Grande Multipara
Total

Deskripsi Usia Kehamilan Preeklampsia
Statistic
Mean
95% Confidence Interval for
Mean

Usia Kehamilan

Std. Error

Lower Bound

36,25
35,57

Upper Bound

36,92

5% Trimmed Mean

36,39

Median

37,00

Variance

9,712

Std. Deviation

3,116

Minimum

28

Maximum

42

Range

14

Interquartile Range

,338

4

Skewness

-,702

,261

Kurtosis

-,117

,517

79

Deskripsi Usia Kehamilan Kelompok Kontrol
Statistic
Mean

38,27

95% Confidence Interval for
Mean

Usia Kehamilan

Std. Error

Lower Bound

37,76

Upper Bound

38,79

5% Trimmed Mean

38,50

Median

39,00

Variance

5,700

Std. Deviation

2,387

Minimum

27

Maximum

42

Range

15

,259

3

Interquartile Range
Skewness
Kurtosis

-1,931

,261

5,917

,517

Frekuensi Usia Kehamilan Preeklampsia Ringan
Frequency

Percent

Valid Percent

Cumulative
Percent

Prematur
Valid

2

15,4

15,4

15,4

Aterm

11

84,6

84,6

100,0

Total

13

100,0

100,0

FrekuensiUsia Kehamilan Preeklampsia Berat
Frequency
Percent
Valid Percent

Valid

Cumulative
Percent

Prematur

24

42,9

42,9

Aterm

30

53,6

53,6

96,4

2

3,6

3,6

100,0

56

100,0

100,0

Serotinus
Total

42,9

FrekuensiUsia Kehamilan Eklampsia
Frequency

Valid

Percent

Valid Percent

Cumulative
Percent

Prematur

9

56,3

56,3

Aterm

6

37,5

37,5

93,8

1
16

6,3
100,0

6,3
100,0

100,0

Serotinus
Total

56,3

80

FrekuensiUsia Kehamilan Kelompok Kontrol
Frequency

Valid

Percent

Valid Percent

Cumulative
Percent

Prematur

10

11,8

11,8

11,8

Aterm

65

76,5

76,5

88,2

Serotinus

10

11,8

11,8

100,0

Total

85

100,0

100,0

Frekuensi ANC Preeklampsia Ringan
Frequency

Valid

Percent

Valid Percent

Cumulative
Percent