Evaluation Pre-hypertension As A Risk Factor Of Acute Coronary Syndrome.
EVALUATION PRE-HYPERTENSION AS A RISK
FACTOR OF ACUTE CORONARY SYNDROME
Disampaikan di 11th intemational congress-asian society of clinical pathology and
laboratory medicine 7th national congress-indonesian association of clinical pathologists,
Jakarta 2010
Sylvia Rachmayati, Ida Parwati, Nanan Sekarwana, Rachmat Soelaeman
Bagian Patologi Klinik
Fakultas Kedokteran Universitas Padjadjaran
Tahun 2010
Evaluation Pre-hypertension as a Risk Factor of Acute Coronary Syndrome
Sylvia Rachmayati* , Ida Parwati* , Nana Sekarwana* * , Rachmat Soalaeman* * *
* Department of Clinical Pathology – Dr. Hasan Sadikin General Hospital Bandung
* * Department of Pediatric - Dr. Hasan Sadikin General Hospital Bandung
* * * Department of Internal Medicine - Dr. Hasan Sadikin General Hospital Bandung
The Seventh Joint National Committee on Prevention, Detection, Evaluation and Treatment
of Hypertension (JNC-7) introduced pre-hypertension (PHT) as a new category defined as
systolic blood pressure (SBP) of 120 to 139 mmHg or diastolic blood pressure (DBP) of 80
to 89 mmHg in young adults aged 25 years or older. Acute Coronary Syndrome (ACS) is a
cardiovascular disease, divided into 3 types: ST elevation Myocardial Infarction (STEMI),
Non-STEMI, and Unstable Angina Pectoris f(lAP), base on Electrocardiogram (ECG),
Creatine Kinase-MB(CKMB), and Troponin T. Individuals with PHT are at high risk of
developing clinical hypertension than those lower BP levels, and also associated with
increased incidence of cardiovascular disease, including ACS. The aim of this study was to
evaluate PHT as a risk factor of ACS.
This preliminary descriptive study was using 60 patients with ACS. The result from this
study found 6 adults patients (4 men and 2 women) with PHT, aged 42 to 52 years old
conducted during April to August 2010. The type of ACS, BP, waist circumference, High
Density Lipoprotein-cholesterol (HDL-c), Triglyceride (7U), and fasting blood glucose
(FBG) were collected. From 6 patients with ACS, 5 patients had STEM! and 1 patient had
UAP. BP among 6 PHT patients were similar (120/ 80 mmHg). High waist circumference
only found in 2 women. Low HDL-c found in 3 patients. High TG is not found in all
patients. High FBG found in 1 patient.
Conclusion: The possibility of ACS in PHT will be increased If accompanied with another risk
factor.
Key w ords: pre-hypertension, acute coronary syndrome
FACTOR OF ACUTE CORONARY SYNDROME
Disampaikan di 11th intemational congress-asian society of clinical pathology and
laboratory medicine 7th national congress-indonesian association of clinical pathologists,
Jakarta 2010
Sylvia Rachmayati, Ida Parwati, Nanan Sekarwana, Rachmat Soelaeman
Bagian Patologi Klinik
Fakultas Kedokteran Universitas Padjadjaran
Tahun 2010
Evaluation Pre-hypertension as a Risk Factor of Acute Coronary Syndrome
Sylvia Rachmayati* , Ida Parwati* , Nana Sekarwana* * , Rachmat Soalaeman* * *
* Department of Clinical Pathology – Dr. Hasan Sadikin General Hospital Bandung
* * Department of Pediatric - Dr. Hasan Sadikin General Hospital Bandung
* * * Department of Internal Medicine - Dr. Hasan Sadikin General Hospital Bandung
The Seventh Joint National Committee on Prevention, Detection, Evaluation and Treatment
of Hypertension (JNC-7) introduced pre-hypertension (PHT) as a new category defined as
systolic blood pressure (SBP) of 120 to 139 mmHg or diastolic blood pressure (DBP) of 80
to 89 mmHg in young adults aged 25 years or older. Acute Coronary Syndrome (ACS) is a
cardiovascular disease, divided into 3 types: ST elevation Myocardial Infarction (STEMI),
Non-STEMI, and Unstable Angina Pectoris f(lAP), base on Electrocardiogram (ECG),
Creatine Kinase-MB(CKMB), and Troponin T. Individuals with PHT are at high risk of
developing clinical hypertension than those lower BP levels, and also associated with
increased incidence of cardiovascular disease, including ACS. The aim of this study was to
evaluate PHT as a risk factor of ACS.
This preliminary descriptive study was using 60 patients with ACS. The result from this
study found 6 adults patients (4 men and 2 women) with PHT, aged 42 to 52 years old
conducted during April to August 2010. The type of ACS, BP, waist circumference, High
Density Lipoprotein-cholesterol (HDL-c), Triglyceride (7U), and fasting blood glucose
(FBG) were collected. From 6 patients with ACS, 5 patients had STEM! and 1 patient had
UAP. BP among 6 PHT patients were similar (120/ 80 mmHg). High waist circumference
only found in 2 women. Low HDL-c found in 3 patients. High TG is not found in all
patients. High FBG found in 1 patient.
Conclusion: The possibility of ACS in PHT will be increased If accompanied with another risk
factor.
Key w ords: pre-hypertension, acute coronary syndrome