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New York
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niversity Sctlool of Medicine
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jill.buyonf{4 1 nyumc.org
Ronald van Vollenhoven, MD phD
Conflict ofinterests
Academic li,ledical Center and VU Unive6ity i/edical Centre
Amsterdam, The Nethedands
rlvanvollenhovenf{amc.nl
Associate Editors
Ricard Cervera
Hospital Clinic of Barcelona
Barcelona, Spain
Email: rce rve ra(Qclinic. ub.es
Lindsey Criswell
UCSF School
of iredicine
San Franciscq USA
Email: lindsey.criswetlQucsiedu
Thomas D6rner
Charite University Hospitals Berlin
Berlin, Germany
Email: thomas.doernerQcharite.de
Lars Riinnblom
Uppsala University
Uppsal4 Sweden
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h@://lqus.bql. cor/pageVeditorial-board/
Brad Rovin
The Ohio State University Wemer
Columbus, USA
Email: brad.rovinQosumcedu
Jane Salmon
Hospital for Special Surgery
NewYorls USA
Email: salmonjQhss.edu
Laura Schanberg
Duke University Medical Centre
Durham, USA
Email: schan001 fQmc.duke.edu
Victoria Werth
University of Pennsylvania
Philadelphia USA
funail: wenhGlmail.med.upenn.edu
Jinoos Yazdazy
University of Califomia at San Francisco
San Francisco, USA
Email: iinoos.yazdany(Iucsf.edu
Social Media Editor
loannis Parodis
Karolinska University Hospital
Stocloolm, Svreden
Editorial Board Members
George Bertsias
University ofCrete
Heraklion, Greece
lan Bruce
University of Manchster
Manchester, UK
Hermine Brunner
Cincinnati Children's Hospital Medical Center
Cincinnati, USA
Eliza Chakravarty
Oklahoma Medical Research Foundation
Oklahoma City, USA
Robert Clancy
Nev{York University School of Medicine
NewYorh USA
Ann Elaine Clarke
University ofCalgary
Calgary, Canada
Nathalie Costedoat-Chalumeau
H6pitalCochin
Paris, France
htp://lupus.bmj.corn/pages/editori al-boardi
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Joseph Craft
Yale University School of Medicine
New Haven, USA
Anne Davidson
Hofstra North Shore
LU
MedicalSchool
Manhasset, USA
Rebecca Fischer
Heinrich-Heine-University
Dusseldorf, Germany
Gary Gilkeson
Medical University South Carolina
Charleston. USA
Bevra Hahn
UCLA David Geffen School of Medicine
LosAngeles, USA
Murat lnanc
Unive.sity oflstanbul
lstanbul,Turkey
Soren Jacobsen
Copenhagen University Hospital
Copenhagen, Denmark
Kenneth Kalunian
University of Califomia at San Diego
San Diego, USA
Annegret Kuhn
University ofMunster
Munstet Germany
Roger Levy
Universidade do Estado do Rio deJaneiro
Rio deJaneiro, Brazil
Michael Lockshin
Hospital for Special Surgery
New Yod! USA
Susan Manzi
West Penn Allegheny Health System
PittsburEh, USA
Ioan Merrill
Oklahoma Medical Research Foundation
0Uahoma City, USA
Chandra Mohan
University ofHouston
Houston USA
Eric Morand
Monash MedicalCentre
Melboume, Australia
Marta Mosca
hrp://lupus.bmj.cor/pages/editorial-board/
University of Pis4 ltaly
Pisa,ltaly
Sandra Navarra
University Santo Tomas Hospital
Manila, Philippines
Chaim Putterman
Alben Einstein College of Medicine
NewYork USA
Anisur Rahman
University Colle8e London
London, UK
Elisabet Svenungsson
Karolinska University Hospital
Stockholm, Sweden
Betty Tsao
David Geffen School of
iledicine University of califomia
LosAngelet USA
Alexandre Voskuyl
VU University Medical Center
Amsterdam, Netherlands
LUPUS
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Table of contents
March 2017 - Volume 4 - Suppl
1
LUPUS 2017 & ACA 2017,(12th lnternational
(
Pr"vi.sre
Congress on SLE & 7tn Asian Congress on
Autoimmunity)
PLENARY SESSION 1: LUPUS lN 2017: FROM MOLECULAR
TARGETS TO NEW THERAPIES
Plenary Session 1: Lupus inZQ17: from moleculartargets to newtherapies
PLENARY SESSION 2: LUPUS NEPHRITIS: FROM BENCH TO
BEDSIDE
Plenary Session 2: Lupus nephritis: from bench to bedside
PLENARY SESSION 3: CHALLENGES IN DRUG
DEVELOPMENTAND CLINICALTRIAL DESIGN IN SLE
Plenary Session 3: Challenges in drug development and clinical trial design in SLE
PLENARY SESSION 4: CUTTING EDGE SCIENCE lN SLE
Plenary Session 4: Cutting edge science in SLE
PLENARY SESSION 5: OUTCOME MEASURES AND
TREATMENT TARGETS IN SLE
Plenary Session 5: Outcome measures and treatment targets in SLE
PARALLEL SESSION 1: CNS LUPUS
Parallel Session 1:CNS lupus
PARALLEL SESSION 2: CELL TARGETING IN SLE
Parallel Session 2: Cell targeting in SLE
PARALLEL SESSION 4: LUPUS REFLECTIONS ACROSS THE
CONTINENTS: ARE WE ADDRESSING THE NEEDS OF OUR
1
dari 4
Nextissue
)
http://lryus.bqi.con/corten 4/Slppl_l
PATIENTS?
ParallelSession 4: Lupus reflections across the continents: are we addressingthe needs
ofourpatients?
PARALLEL SESSION 5: LUPUS NEPHRITIS
Parallel Session 5: Lupus nephritis
PARALLEL SESSION 7: MANIFESTATIONS, COMORBtDtTtES
AND COMPLICATIONS
Parallel Session 7t Manifestations, comorbidities and complications
PARALLEL SESSION 8: INNATE tMMUNtTY AND
INTERFERON
Parallel Session 8: lnnate immunity and interferon
PARALLEL SESSION 9: THE MOSATC OF AUTO|MMUNtTy
Parall€l Session 9:The mosaic of
PARALLEL SESSION
autoimmunity
APS
1
O:
1
1: EFFECTOR T CELLS tN SLE
Parallel Session 10: APS
PARALLEL SESSION
ParallelSession
1
1:
EffectorT cells in SLE
PARALLEL SESSION 15: PEARLS lN AUTO|MMUNtTy
ParallelSession 15: Peads in autoimmunity
PARALLEL SESSION 16: QUAL|Ty OF CARE AND pATtENT
REPORTED OUTCOMES
ParallelSession
1
6:
Quality of care and patient reported outcomes
PARALLEL SESSION 18: AUTOIMMUNtTy AND THE
ENVIRONMENT
ParallelSession 18: Autoimmunity and the environment
FREE COMMUNICATIONS 1
Free
Communications 'l
-
_
BIOMARKER DISCOVERY
Biomarker discovery
POSTER SESSION
PosterSession
ADAPTIVE IMMUNITY AND LYMPHOCYTES
2 dart 4
http
Adaptive immunity and lymphoqltes
ANTIPHOSPHOLIPI D SYN DROME
Antiphospholi pid syndrome
NEW THERAPIES AND THERAPEUTIC TARGETS _ OTHER
AUTOIMMUNE DISEASES
New therapies and therapeutic targets
-
other autoimmune diseases
NEW THERAPIES AND THERAPEUTIC TARGETS
New therapies and therapeutic targets
-
-
SLE
SLE
OTHER BASIC SCIENCE
Other basic science
PAEDIATRIC SLE
Paediatric SLE
PATI
E
NT.S
U BM
ITTED ABSTRACTS
Patient-submitted abstracts
SLE COMPL]CATIONS AND COMORBIDITIES
SLE Complications and
comorbidities
CLINICAL TRIALS
Clinical trials
GENETICS, EPIGENETICS, OMICS, BIOMARKERS AND
PERSONALISED MEDICINE IN SLE AND AUTOIMMUNITY
Genetics, epigenetics, omics, biomarkers and personalised medicine in sLE and
autoimmunity
INNATE IMMUNITY
lnnate immunity
INNATE IMMUNITY
lnnate immunity
MICROBIOME, INFECTIONS, PROBIOTICS AND
NUTRITIONAL FACTORS IN AUTOIMMUNITY
Microbiome, infections, probiotics and nutritional factors in autoimmunity
3 dari
4
:
//lryus.bn{ com/content/4/Suppl_l
.
http //lupus.bmj com/content/4lSuppl_1
!
:
.
PREGNANCY: THE MOTHER AND THE CHILD
Pregnancy: the mother and the
child
u
SLE EPIDEMIOLOGY AND RISK FACTORS
SLE Epidemiology and risk
factors
VACC I N ES, ADJUVANTS AN D AUTOIMMUN ITY
Vaccines, adiuvants and
autoimmunity
ISSUE INFORMATION
Front Cover
LUPUS
FOUNDATION OF AMERICA
CONTENT
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PublishingGroup Ltd &Lupus Foundation ofAmerica. All rights reserved.
tilcPfi'lso42o4oB-3
4 dari 4
hpp://lupus.bqi.conr/search,/volurne:4
issue:Suppl+1?fac€tltoc-section-idl[0]=Plenary Session 2:
r,
BMJ
llpus nephritis:
from bench to bedside
6tt ArnrJd lr,l|6dE of fp U$aAcadenry
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forvolume "4" and issue "Suppl 1"
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P.3tM.tch
M Rathi, H Prasad, ASharma, R Nad4 KL Gupta
5 lmpact of vascular involvement on outcomes in patientswith lupus nephritis
FREE
Lupus Science & Medicine Mar 201Z 4 6uppl 1) A2; DOI: 10.1 136/luPus-2o170002'l
55
N Nurdiana, U Kalsum, ESariDewi, K Handono, H Kaliim
4 Accelerated lupus nephritis associated with increased t helper subset, serum tnfa
and anti dsdna levels in pregnant pristane induced lupus
mice rmr
Lupus Science & Medicine Mar201Z 4 (SupPl 1) A2; DOI: 10.1 136/lupus-2017-Oco215.4
LU.)US
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N
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IC A
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Downloaded ,rom http://luprs.bmj.com/ on April 20, 2017 - Publishod by group bmj.com
4 Accelerated lupus nephritis associated with
increased t helper subset, serum tnfa and
anti dsdna levels in pregnant pristane
induced lupus mice
N Nurdiana, U Kalsum, E Sari Dewi, K Handono and H Kaliim
Lupus Sci Med 2017 4:
doi:
1
0.
11
P2.
36/lupus-201 7-0002'l 5.4
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Abstracts
effecr on gene expression, transcription facor binding, and
epigenetic characeristics. Using the correlated SNPS (r2 >0.8)
from the 82 SLE loci, we found only 1.5% SNPs errcode missense or synooymous mutations, altd the marority (56%) were
implicated in differenrial exprcssion of cis-genes (9.81
1GI 98
.
LUPUS
SCIENCE&
MEDICINE-
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Editorial Board
Editors-in-Chief
jill
Buyon, MD
Conflict of interests
New York
U
niversity Sctlool of Medicine
NewYork USA
jill.buyonf{4 1 nyumc.org
Ronald van Vollenhoven, MD phD
Conflict ofinterests
Academic li,ledical Center and VU Unive6ity i/edical Centre
Amsterdam, The Nethedands
rlvanvollenhovenf{amc.nl
Associate Editors
Ricard Cervera
Hospital Clinic of Barcelona
Barcelona, Spain
Email: rce rve ra(Qclinic. ub.es
Lindsey Criswell
UCSF School
of iredicine
San Franciscq USA
Email: lindsey.criswetlQucsiedu
Thomas D6rner
Charite University Hospitals Berlin
Berlin, Germany
Email: thomas.doernerQcharite.de
Lars Riinnblom
Uppsala University
Uppsal4 Sweden
Email: lars.ronnblomfimedsci.uu.se
h@://lqus.bql. cor/pageVeditorial-board/
Brad Rovin
The Ohio State University Wemer
Columbus, USA
Email: brad.rovinQosumcedu
Jane Salmon
Hospital for Special Surgery
NewYorls USA
Email: salmonjQhss.edu
Laura Schanberg
Duke University Medical Centre
Durham, USA
Email: schan001 fQmc.duke.edu
Victoria Werth
University of Pennsylvania
Philadelphia USA
funail: wenhGlmail.med.upenn.edu
Jinoos Yazdazy
University of Califomia at San Francisco
San Francisco, USA
Email: iinoos.yazdany(Iucsf.edu
Social Media Editor
loannis Parodis
Karolinska University Hospital
Stocloolm, Svreden
Editorial Board Members
George Bertsias
University ofCrete
Heraklion, Greece
lan Bruce
University of Manchster
Manchester, UK
Hermine Brunner
Cincinnati Children's Hospital Medical Center
Cincinnati, USA
Eliza Chakravarty
Oklahoma Medical Research Foundation
Oklahoma City, USA
Robert Clancy
Nev{York University School of Medicine
NewYorh USA
Ann Elaine Clarke
University ofCalgary
Calgary, Canada
Nathalie Costedoat-Chalumeau
H6pitalCochin
Paris, France
htp://lupus.bmj.corn/pages/editori al-boardi
l
Joseph Craft
Yale University School of Medicine
New Haven, USA
Anne Davidson
Hofstra North Shore
LU
MedicalSchool
Manhasset, USA
Rebecca Fischer
Heinrich-Heine-University
Dusseldorf, Germany
Gary Gilkeson
Medical University South Carolina
Charleston. USA
Bevra Hahn
UCLA David Geffen School of Medicine
LosAngeles, USA
Murat lnanc
Unive.sity oflstanbul
lstanbul,Turkey
Soren Jacobsen
Copenhagen University Hospital
Copenhagen, Denmark
Kenneth Kalunian
University of Califomia at San Diego
San Diego, USA
Annegret Kuhn
University ofMunster
Munstet Germany
Roger Levy
Universidade do Estado do Rio deJaneiro
Rio deJaneiro, Brazil
Michael Lockshin
Hospital for Special Surgery
New Yod! USA
Susan Manzi
West Penn Allegheny Health System
PittsburEh, USA
Ioan Merrill
Oklahoma Medical Research Foundation
0Uahoma City, USA
Chandra Mohan
University ofHouston
Houston USA
Eric Morand
Monash MedicalCentre
Melboume, Australia
Marta Mosca
hrp://lupus.bmj.cor/pages/editorial-board/
University of Pis4 ltaly
Pisa,ltaly
Sandra Navarra
University Santo Tomas Hospital
Manila, Philippines
Chaim Putterman
Alben Einstein College of Medicine
NewYork USA
Anisur Rahman
University Colle8e London
London, UK
Elisabet Svenungsson
Karolinska University Hospital
Stockholm, Sweden
Betty Tsao
David Geffen School of
iledicine University of califomia
LosAngelet USA
Alexandre Voskuyl
VU University Medical Center
Amsterdam, Netherlands
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Table of contents
March 2017 - Volume 4 - Suppl
1
LUPUS 2017 & ACA 2017,(12th lnternational
(
Pr"vi.sre
Congress on SLE & 7tn Asian Congress on
Autoimmunity)
PLENARY SESSION 1: LUPUS lN 2017: FROM MOLECULAR
TARGETS TO NEW THERAPIES
Plenary Session 1: Lupus inZQ17: from moleculartargets to newtherapies
PLENARY SESSION 2: LUPUS NEPHRITIS: FROM BENCH TO
BEDSIDE
Plenary Session 2: Lupus nephritis: from bench to bedside
PLENARY SESSION 3: CHALLENGES IN DRUG
DEVELOPMENTAND CLINICALTRIAL DESIGN IN SLE
Plenary Session 3: Challenges in drug development and clinical trial design in SLE
PLENARY SESSION 4: CUTTING EDGE SCIENCE lN SLE
Plenary Session 4: Cutting edge science in SLE
PLENARY SESSION 5: OUTCOME MEASURES AND
TREATMENT TARGETS IN SLE
Plenary Session 5: Outcome measures and treatment targets in SLE
PARALLEL SESSION 1: CNS LUPUS
Parallel Session 1:CNS lupus
PARALLEL SESSION 2: CELL TARGETING IN SLE
Parallel Session 2: Cell targeting in SLE
PARALLEL SESSION 4: LUPUS REFLECTIONS ACROSS THE
CONTINENTS: ARE WE ADDRESSING THE NEEDS OF OUR
1
dari 4
Nextissue
)
http://lryus.bqi.con/corten 4/Slppl_l
PATIENTS?
ParallelSession 4: Lupus reflections across the continents: are we addressingthe needs
ofourpatients?
PARALLEL SESSION 5: LUPUS NEPHRITIS
Parallel Session 5: Lupus nephritis
PARALLEL SESSION 7: MANIFESTATIONS, COMORBtDtTtES
AND COMPLICATIONS
Parallel Session 7t Manifestations, comorbidities and complications
PARALLEL SESSION 8: INNATE tMMUNtTY AND
INTERFERON
Parallel Session 8: lnnate immunity and interferon
PARALLEL SESSION 9: THE MOSATC OF AUTO|MMUNtTy
Parall€l Session 9:The mosaic of
PARALLEL SESSION
autoimmunity
APS
1
O:
1
1: EFFECTOR T CELLS tN SLE
Parallel Session 10: APS
PARALLEL SESSION
ParallelSession
1
1:
EffectorT cells in SLE
PARALLEL SESSION 15: PEARLS lN AUTO|MMUNtTy
ParallelSession 15: Peads in autoimmunity
PARALLEL SESSION 16: QUAL|Ty OF CARE AND pATtENT
REPORTED OUTCOMES
ParallelSession
1
6:
Quality of care and patient reported outcomes
PARALLEL SESSION 18: AUTOIMMUNtTy AND THE
ENVIRONMENT
ParallelSession 18: Autoimmunity and the environment
FREE COMMUNICATIONS 1
Free
Communications 'l
-
_
BIOMARKER DISCOVERY
Biomarker discovery
POSTER SESSION
PosterSession
ADAPTIVE IMMUNITY AND LYMPHOCYTES
2 dart 4
http
Adaptive immunity and lymphoqltes
ANTIPHOSPHOLIPI D SYN DROME
Antiphospholi pid syndrome
NEW THERAPIES AND THERAPEUTIC TARGETS _ OTHER
AUTOIMMUNE DISEASES
New therapies and therapeutic targets
-
other autoimmune diseases
NEW THERAPIES AND THERAPEUTIC TARGETS
New therapies and therapeutic targets
-
-
SLE
SLE
OTHER BASIC SCIENCE
Other basic science
PAEDIATRIC SLE
Paediatric SLE
PATI
E
NT.S
U BM
ITTED ABSTRACTS
Patient-submitted abstracts
SLE COMPL]CATIONS AND COMORBIDITIES
SLE Complications and
comorbidities
CLINICAL TRIALS
Clinical trials
GENETICS, EPIGENETICS, OMICS, BIOMARKERS AND
PERSONALISED MEDICINE IN SLE AND AUTOIMMUNITY
Genetics, epigenetics, omics, biomarkers and personalised medicine in sLE and
autoimmunity
INNATE IMMUNITY
lnnate immunity
INNATE IMMUNITY
lnnate immunity
MICROBIOME, INFECTIONS, PROBIOTICS AND
NUTRITIONAL FACTORS IN AUTOIMMUNITY
Microbiome, infections, probiotics and nutritional factors in autoimmunity
3 dari
4
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.
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.
PREGNANCY: THE MOTHER AND THE CHILD
Pregnancy: the mother and the
child
u
SLE EPIDEMIOLOGY AND RISK FACTORS
SLE Epidemiology and risk
factors
VACC I N ES, ADJUVANTS AN D AUTOIMMUN ITY
Vaccines, adiuvants and
autoimmunity
ISSUE INFORMATION
Front Cover
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FOUNDATION OF AMERICA
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BMJ
PublishingGroup Ltd &Lupus Foundation ofAmerica. All rights reserved.
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4 dari 4
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issue:Suppl+1?fac€tltoc-section-idl[0]=Plenary Session 2:
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llpus nephritis:
from bench to bedside
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2 results
forvolume "4" and issue "Suppl 1"
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M Rathi, H Prasad, ASharma, R Nad4 KL Gupta
5 lmpact of vascular involvement on outcomes in patientswith lupus nephritis
FREE
Lupus Science & Medicine Mar 201Z 4 6uppl 1) A2; DOI: 10.1 136/luPus-2o170002'l
55
N Nurdiana, U Kalsum, ESariDewi, K Handono, H Kaliim
4 Accelerated lupus nephritis associated with increased t helper subset, serum tnfa
and anti dsdna levels in pregnant pristane induced lupus
mice rmr
Lupus Science & Medicine Mar201Z 4 (SupPl 1) A2; DOI: 10.1 136/lupus-2017-Oco215.4
LU.)US
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Downloaded ,rom http://luprs.bmj.com/ on April 20, 2017 - Publishod by group bmj.com
4 Accelerated lupus nephritis associated with
increased t helper subset, serum tnfa and
anti dsdna levels in pregnant pristane
induced lupus mice
N Nurdiana, U Kalsum, E Sari Dewi, K Handono and H Kaliim
Lupus Sci Med 2017 4:
doi:
1
0.
11
P2.
36/lupus-201 7-0002'l 5.4
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Abstracts
effecr on gene expression, transcription facor binding, and
epigenetic characeristics. Using the correlated SNPS (r2 >0.8)
from the 82 SLE loci, we found only 1.5% SNPs errcode missense or synooymous mutations, altd the marority (56%) were
implicated in differenrial exprcssion of cis-genes (9.81
1GI 98