PENINGKATAN KADAR NITRIC OXIDE DAN OSTEOKALSIN PADA TIKUS SPRAGUE DAWLEY YANG DIBERI ASAM LEMAK TRANS DOSIS TINGGI - Diponegoro University | Institutional Repository (UNDIP-IR)
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Kelompok
b,c
Tes ts of Norm ality
a
NO 8 mgg
Osteocalcin 0 mgg
Osteocalcin 8 mgg
Delta NO 8
Delta Os 8
Kelompok
Kelompok 1
Kelompok 2
Kelompok 1
Kelompok 2
Kelompok 1
Kelompok 2
Kelompok 1
Kelompok 2
Kelompok 1
Kelompok 2
Kolmogorov-Smirnov
Statistic
df
Sig.
.524
10
.000
.227
10
.154
.212
10
.200*
.177
10
.200*
.256
10
.063
.293
10
.015
.524
10
.000
.227
10
.154
.323
10
.004
.171
10
.200*
Statistic
.366
.876
.908
.962
.875
.868
.366
.876
.764
.923
Shapiro-Wilk
df
10
10
10
10
10
10
10
10
10
10
*. This is a low er bound of the true signif ic anc e.
a. Lillief ors Signif icance Correc tion
b. NO 0 mgg is cons tant w hen Kelompok = Kelompok 1. It has been omitted.
c. NO 0 mgg is cons tant w hen Kelompok = Kelompok 2. It has been omitted.
Tables
Kelo
mpok
Kelompok 1
Kelompok 2
NO 0 mgg
NO 8 mgg
Osteocalcin 0 mgg
Osteocalcin 8 mgg
Delta NO 8
Delta Os 8
NO 0 mgg
NO 8 mgg
Osteocalcin 0 mgg
Osteocalcin 8 mgg
Delta NO 8
Delta Os 8
Count
10
10
10
10
10
10
10
10
10
10
10
10
xxviii
Mean
2.4
2.44
84.17
84.80
.04
.63
2.4
9.52
83.86
100.89
7.12
15.28
SD
.0
.13
2.29
2.14
.13
.53
.0
3.84
2.38
9.73
3.84
9.14
Min
2.4
2.40
81.20
82.50
.00
.10
2.4
4.20
80.60
87.60
1.80
2.10
Max
2.4
2.80
88.20
88.70
.40
1.90
2.4
14.30
88.20
113.6
11.90
27.40
Med
2.4
2.40
83.50
84.30
.00
.45
2.4
8.30
83.50
105.80
5.90
16.35
Sig.
.000
.116
.268
.809
.113
.094
.000
.116
.005
.380
T-Test
Group Statis tics
NO 0 mgg
NO 8 mgg
Osteocalcin 0 mgg
Osteocalcin 8 mgg
Delta NO 8
Delta Os 8
Kelompok
Kelompok 1
Kelompok 2
Kelompok 1
Kelompok 2
Kelompok 1
Kelompok 2
Kelompok 1
Kelompok 2
Kelompok 1
Kelompok 2
Kelompok 1
Kelompok 2
N
10
10
10
10
10
10
10
10
10
10
10
10
Mean
2.400
2.400
2.4400
9.5200
84.1700
83.8600
84.8000
100.8900
.0400
7.1200
.6300
15.2800
Std. Deviation
.0000a
.0000a
.12649
3.83979
2.29349
2.38383
2.14476
9.72985
.12649
3.83979
.52926
9.14170
Std. Error
Mean
.0000
.0000
.04000
1.21425
.72527
.75383
.67823
3.07685
.04000
1.21425
.16737
2.89086
a. t c annot be computed bec ause the standard dev iations of both groups are 0.
xxix
Inde pe nde nt Sam ples Te st
Levene's Test for
Equality of
Varianc es
F
NO 8 mgg
Osteocalcin 0 mgg
Osteocalcin 8 mgg
Delta NO 8
Delta Os 8
Equal variances
as sumed
Equal variances
not assumed
Equal variances
as sumed
Equal variances
not assumed
Equal variances
as sumed
Equal variances
not assumed
Equal variances
as sumed
Equal variances
not assumed
Equal variances
as sumed
Equal variances
not assumed
Sig.
42.684
.002
31.690
42.684
46.268
.000
.966
.000
.000
.000
t-test for Equality of Means
t
df
Delta NO 8
Delta Os 8
N
10
10
20
10
10
20
10
10
20
.000
-7.0800
1.21491
-9.632
-4.
-5.828
9.020
.000
-7.0800
1.21491
-9.827
-4.
.296
18
.770
.3100
1.04608
-1.888
2.5
.296 17.973
.770
.3100
1.04608
-1.888
2.5
-5.107
18
.000
-16.0900
3.15071
-22.71
-9.
-5.107
9.873
.000
-16.0900
3.15071
-23.12
-9.
-5.828
18
.000
-7.0800
1.21491
-9.632
-4.
-5.828
9.020
.000
-7.0800
1.21491
-9.827
-4.
-5.059
18
.000
-14.6500
2.89570
-20.73
-8.
-5.059
9.060
.001
-14.6500
2.89570
-21.19
-8.
Mean Rank
5.50
15.50
Sum of Ranks
55.00
155.00
5.50
15.50
55.00
155.00
5.50
15.50
55.00
155.00
xxx
Std. Error
Differenc
e
18
Ranks
Kelompok
Kelompok 1
Kelompok 2
Total
Kelompok 1
Kelompok 2
Total
Kelompok 1
Kelompok 2
Total
Mean
Differenc
e
-5.828
NPar Tests
Mann-Whitney Test
NO 8 mgg
Sig.
(2-tailed)
95% Confide
Interval of t
Difference
Low er Up
Tes t Statis ticsb
Mann-Whitney U
Wilc oxon W
Z
Asy mp. Sig. (2-tailed)
Ex ac t Sig. [2*(1-tailed
Sig.)]
NO 8 mgg
.000
55.000
-3.963
.000
.000
Delta NO 8
.000
55.000
-3.963
.000
a
.000
Delta Os 8
.000
55.000
-3.787
.000
a
.000
a
a. Not c orrec ted f or ties.
b. Grouping Variable: Kelompok
T-Test
Paired Sam ples Statis tics
Pair
1
Pair
2
NO 0 mgg
NO 8 mgg
Osteocalcin 0 mgg
Osteocalcin 8 mgg
Mean
2.400
2.4400
84.1700
84.8000
K1
N
10
10
10
10
Paired Samples Corre lations
N
Pair 1
Pair 2
NO 0 mgg & NO 8 mgg
Osteocalcin 0 mgg &
Osteocalcin 8 mgg
Std. Error
Mean
.0000
.04000
.72527
.67823
Std. Deviation
.0000
.12649
2.29349
2.14476
K1
10
Correlation
.
10
.974
Sig.
.
.000
Paired Sam ples Te st
Pair 1
Pair 2
NO 0 mgg - NO 8 mgg
Osteocalcin 0 mgg Osteocalcin 8 mgg
Mean
-.0400
-.6300
K1
Paired Dif f erences
95% Conf idence
Interval of the
Std.
Dif f erence
Std.
Error
Deviation
Mean
Low er
Upper
.12649
.04000
-.1305
.0505
.52926
NPar Tests
Wilcoxon Signed Ranks Test
xxxi
.16737 -1.0086
-.2514
t
-1.000
df
9
Sig.
(2-tailed)
.343
-3.764
9
.004
Ranks
K1
N
NO 8 mgg - NO 0 mgg
0a
1b
9c
10
Negative Ranks
Positive Ranks
Ties
Total
a. NO 8 mgg < NO 0 mgg
b. NO 8 mgg > NO 0 mgg
c. NO 8 mgg = NO 0 mgg
K1
b
Tes t Statistics
Z
A sy mp. Sig. (2-tailed)
NO 8 mgg NO 0 mgg
-1.000a
.317
a. Based on negative ranks.
b. Wilc oxon Signed Ranks Tes t
Correlations
Nonparametric Correlations
xxxii
Mean Rank
.00
1.00
Sum of Ranks
.00
1.00
Correlations
Spearman's rho
Delta NO 8
K1
Delta NO 8
1.000
Correlation Coefficient
Sig. (2-tailed)
.
N
Delta Os 8
Delta Os 8
-.530
Correlation Coefficient
.115
10
10
-.530
1.000
Sig. (2-tailed)
.115
.
10
10
N
T-Test
Paired Sam ples Statis tics
Pair
1
Pair
2
NO 0 mgg
NO 8 mgg
Osteocalcin 0 mgg
Osteocalcin 8 mgg
Mean
2.400
9.5200
83.8600
100.8900
K2
N
10
10
10
10
Paired Samples Corre lations
N
Pair 1
Pair 2
NO 0 mgg & NO 8 mgg
Osteocalcin 0 mgg &
Osteocalcin 8 mgg
Std. Error
Mean
.0000
1.21425
.75383
3.07685
Std. Deviation
.0000
3.83979
2.38383
9.72985
K2
10
Correlation
.
10
.387
Sig.
.
.269
Paired Sam ples Te st
Pair 1
Pair 2
NO 0 mgg - NO 8 mgg
Osteocalcin 0 mgg Osteocalcin 8 mgg
Mean
-7.1200
-17.03
K2
Paired Dif f erences
95% Conf idence
Interval of the
Std.
Dif f erence
Std.
Error
Deviation
Mean
Low er
Upper
3.83979 1.21425 -9.867 -4.3732
9.07659 2.87027
Correlations
xxxiii
-23.52
-10.54
t
-5.86
-5.93
9
Sig.
(2-tailed)
.000
9
.000
df
Cor relations
Delta NO 8
Delta Os 8
Pears on Correlation
Sig. (2-tailed)
N
Pears on Correlation
Sig. (2-tailed)
N
K2
Delta NO 8 Delta Os 8
1
.848**
.
.002
10
10
.848**
1
.002
.
10
10
**. Correlation is s ignif icant at the 0.01 level (2-tailed).
xxxiv
Kelompok
b,c
Tes ts of Norm ality
a
NO 8 mgg
Osteocalcin 0 mgg
Osteocalcin 8 mgg
Delta NO 8
Delta Os 8
Kelompok
Kelompok 1
Kelompok 2
Kelompok 1
Kelompok 2
Kelompok 1
Kelompok 2
Kelompok 1
Kelompok 2
Kelompok 1
Kelompok 2
Kolmogorov-Smirnov
Statistic
df
Sig.
.524
10
.000
.227
10
.154
.212
10
.200*
.177
10
.200*
.256
10
.063
.293
10
.015
.524
10
.000
.227
10
.154
.323
10
.004
.171
10
.200*
Statistic
.366
.876
.908
.962
.875
.868
.366
.876
.764
.923
Shapiro-Wilk
df
10
10
10
10
10
10
10
10
10
10
*. This is a low er bound of the true signif ic anc e.
a. Lillief ors Signif icance Correc tion
b. NO 0 mgg is cons tant w hen Kelompok = Kelompok 1. It has been omitted.
c. NO 0 mgg is cons tant w hen Kelompok = Kelompok 2. It has been omitted.
Tables
Kelo
mpok
Kelompok 1
Kelompok 2
NO 0 mgg
NO 8 mgg
Osteocalcin 0 mgg
Osteocalcin 8 mgg
Delta NO 8
Delta Os 8
NO 0 mgg
NO 8 mgg
Osteocalcin 0 mgg
Osteocalcin 8 mgg
Delta NO 8
Delta Os 8
Count
10
10
10
10
10
10
10
10
10
10
10
10
xxviii
Mean
2.4
2.44
84.17
84.80
.04
.63
2.4
9.52
83.86
100.89
7.12
15.28
SD
.0
.13
2.29
2.14
.13
.53
.0
3.84
2.38
9.73
3.84
9.14
Min
2.4
2.40
81.20
82.50
.00
.10
2.4
4.20
80.60
87.60
1.80
2.10
Max
2.4
2.80
88.20
88.70
.40
1.90
2.4
14.30
88.20
113.6
11.90
27.40
Med
2.4
2.40
83.50
84.30
.00
.45
2.4
8.30
83.50
105.80
5.90
16.35
Sig.
.000
.116
.268
.809
.113
.094
.000
.116
.005
.380
T-Test
Group Statis tics
NO 0 mgg
NO 8 mgg
Osteocalcin 0 mgg
Osteocalcin 8 mgg
Delta NO 8
Delta Os 8
Kelompok
Kelompok 1
Kelompok 2
Kelompok 1
Kelompok 2
Kelompok 1
Kelompok 2
Kelompok 1
Kelompok 2
Kelompok 1
Kelompok 2
Kelompok 1
Kelompok 2
N
10
10
10
10
10
10
10
10
10
10
10
10
Mean
2.400
2.400
2.4400
9.5200
84.1700
83.8600
84.8000
100.8900
.0400
7.1200
.6300
15.2800
Std. Deviation
.0000a
.0000a
.12649
3.83979
2.29349
2.38383
2.14476
9.72985
.12649
3.83979
.52926
9.14170
Std. Error
Mean
.0000
.0000
.04000
1.21425
.72527
.75383
.67823
3.07685
.04000
1.21425
.16737
2.89086
a. t c annot be computed bec ause the standard dev iations of both groups are 0.
xxix
Inde pe nde nt Sam ples Te st
Levene's Test for
Equality of
Varianc es
F
NO 8 mgg
Osteocalcin 0 mgg
Osteocalcin 8 mgg
Delta NO 8
Delta Os 8
Equal variances
as sumed
Equal variances
not assumed
Equal variances
as sumed
Equal variances
not assumed
Equal variances
as sumed
Equal variances
not assumed
Equal variances
as sumed
Equal variances
not assumed
Equal variances
as sumed
Equal variances
not assumed
Sig.
42.684
.002
31.690
42.684
46.268
.000
.966
.000
.000
.000
t-test for Equality of Means
t
df
Delta NO 8
Delta Os 8
N
10
10
20
10
10
20
10
10
20
.000
-7.0800
1.21491
-9.632
-4.
-5.828
9.020
.000
-7.0800
1.21491
-9.827
-4.
.296
18
.770
.3100
1.04608
-1.888
2.5
.296 17.973
.770
.3100
1.04608
-1.888
2.5
-5.107
18
.000
-16.0900
3.15071
-22.71
-9.
-5.107
9.873
.000
-16.0900
3.15071
-23.12
-9.
-5.828
18
.000
-7.0800
1.21491
-9.632
-4.
-5.828
9.020
.000
-7.0800
1.21491
-9.827
-4.
-5.059
18
.000
-14.6500
2.89570
-20.73
-8.
-5.059
9.060
.001
-14.6500
2.89570
-21.19
-8.
Mean Rank
5.50
15.50
Sum of Ranks
55.00
155.00
5.50
15.50
55.00
155.00
5.50
15.50
55.00
155.00
xxx
Std. Error
Differenc
e
18
Ranks
Kelompok
Kelompok 1
Kelompok 2
Total
Kelompok 1
Kelompok 2
Total
Kelompok 1
Kelompok 2
Total
Mean
Differenc
e
-5.828
NPar Tests
Mann-Whitney Test
NO 8 mgg
Sig.
(2-tailed)
95% Confide
Interval of t
Difference
Low er Up
Tes t Statis ticsb
Mann-Whitney U
Wilc oxon W
Z
Asy mp. Sig. (2-tailed)
Ex ac t Sig. [2*(1-tailed
Sig.)]
NO 8 mgg
.000
55.000
-3.963
.000
.000
Delta NO 8
.000
55.000
-3.963
.000
a
.000
Delta Os 8
.000
55.000
-3.787
.000
a
.000
a
a. Not c orrec ted f or ties.
b. Grouping Variable: Kelompok
T-Test
Paired Sam ples Statis tics
Pair
1
Pair
2
NO 0 mgg
NO 8 mgg
Osteocalcin 0 mgg
Osteocalcin 8 mgg
Mean
2.400
2.4400
84.1700
84.8000
K1
N
10
10
10
10
Paired Samples Corre lations
N
Pair 1
Pair 2
NO 0 mgg & NO 8 mgg
Osteocalcin 0 mgg &
Osteocalcin 8 mgg
Std. Error
Mean
.0000
.04000
.72527
.67823
Std. Deviation
.0000
.12649
2.29349
2.14476
K1
10
Correlation
.
10
.974
Sig.
.
.000
Paired Sam ples Te st
Pair 1
Pair 2
NO 0 mgg - NO 8 mgg
Osteocalcin 0 mgg Osteocalcin 8 mgg
Mean
-.0400
-.6300
K1
Paired Dif f erences
95% Conf idence
Interval of the
Std.
Dif f erence
Std.
Error
Deviation
Mean
Low er
Upper
.12649
.04000
-.1305
.0505
.52926
NPar Tests
Wilcoxon Signed Ranks Test
xxxi
.16737 -1.0086
-.2514
t
-1.000
df
9
Sig.
(2-tailed)
.343
-3.764
9
.004
Ranks
K1
N
NO 8 mgg - NO 0 mgg
0a
1b
9c
10
Negative Ranks
Positive Ranks
Ties
Total
a. NO 8 mgg < NO 0 mgg
b. NO 8 mgg > NO 0 mgg
c. NO 8 mgg = NO 0 mgg
K1
b
Tes t Statistics
Z
A sy mp. Sig. (2-tailed)
NO 8 mgg NO 0 mgg
-1.000a
.317
a. Based on negative ranks.
b. Wilc oxon Signed Ranks Tes t
Correlations
Nonparametric Correlations
xxxii
Mean Rank
.00
1.00
Sum of Ranks
.00
1.00
Correlations
Spearman's rho
Delta NO 8
K1
Delta NO 8
1.000
Correlation Coefficient
Sig. (2-tailed)
.
N
Delta Os 8
Delta Os 8
-.530
Correlation Coefficient
.115
10
10
-.530
1.000
Sig. (2-tailed)
.115
.
10
10
N
T-Test
Paired Sam ples Statis tics
Pair
1
Pair
2
NO 0 mgg
NO 8 mgg
Osteocalcin 0 mgg
Osteocalcin 8 mgg
Mean
2.400
9.5200
83.8600
100.8900
K2
N
10
10
10
10
Paired Samples Corre lations
N
Pair 1
Pair 2
NO 0 mgg & NO 8 mgg
Osteocalcin 0 mgg &
Osteocalcin 8 mgg
Std. Error
Mean
.0000
1.21425
.75383
3.07685
Std. Deviation
.0000
3.83979
2.38383
9.72985
K2
10
Correlation
.
10
.387
Sig.
.
.269
Paired Sam ples Te st
Pair 1
Pair 2
NO 0 mgg - NO 8 mgg
Osteocalcin 0 mgg Osteocalcin 8 mgg
Mean
-7.1200
-17.03
K2
Paired Dif f erences
95% Conf idence
Interval of the
Std.
Dif f erence
Std.
Error
Deviation
Mean
Low er
Upper
3.83979 1.21425 -9.867 -4.3732
9.07659 2.87027
Correlations
xxxiii
-23.52
-10.54
t
-5.86
-5.93
9
Sig.
(2-tailed)
.000
9
.000
df
Cor relations
Delta NO 8
Delta Os 8
Pears on Correlation
Sig. (2-tailed)
N
Pears on Correlation
Sig. (2-tailed)
N
K2
Delta NO 8 Delta Os 8
1
.848**
.
.002
10
10
.848**
1
.002
.
10
10
**. Correlation is s ignif icant at the 0.01 level (2-tailed).
xxxiv