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The influence of Red Grapes Extract (Vitis vinifera L) to the Blood Triglyceride Levels White rats (Rattus novergicuss)

ARTIKEL PENELITIAN

Mutiara Medika
Vol. 11 No. 3: 175-180, September 2011

Pengaruh Ekstrak Buah Anggur Merah (Vitis vinifera L) terhadap Kadar
Trigliserida Darah Tikus Putih (Rattus novergicuss)
The influence of Red Grapes Extract (Vitis vinifera L) to the Blood
Triglyceride Levels White rats (Rattus novergicuss)
Salmah Orbayinah2*, Kurnia Eka Permana1
1
Program Studi Kedokteran Umum, Fakultas Kedokteran, Universitas Muhammadiyah Yogyakarta,
2
Departemen Biokimia, Fakultas Kedokteran, Universitas Muhammadiyah Yogyakarta
*Email: [email protected]
Abstrak
Buah anggur memiliki kandungan proanthosianidin dan resveratrol yang berkaitan erat dengan
pencegahan hiperlipidemia khususnya hipertrigliserida. Penelitian ini bertujuan untuk mengetahui
pengaruh ekstrak buah anggur merah (Vitis viniferra L.) terhadap kadar trigliserida darah tikus putih
(Rattus norvegicus). Ekstrak anggur merah dibuat dalam berbagai dosis. Dosis I (100mg/200g BB/hari),
dosis II(250mg/200g BB/2ml), dan dosis III (500mg/200g BB/hari). Pemberian ekstrak anggur merah

dilakukan selama 10 hari. Hasil yang diperoleh menunjukkan bahwa terdapat perbedaan kadar trigliserida
yang signifikan sebelum dan sesudah perlakuan pada masing masing kelompok nilai (p

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