DEVELOPMENT OF MELOXICAM TRANSDERMAL MATRIX TYPE PATCH USING POLYVINYLPYRROLIDONE, HYDROXYPROPYL METHYCELLULOSE, AND ETHYL CELLULOSE COMBINATION

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Drug Deiivery Systems:
From Drug-Discovery, Pre-formulaticn, Formulation and Technological Approaches for
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The l"t lnternational conference on Pharmaceutics
& Pharmaceutical Sciences Proceedings
ISBN : 97 8-5A2-72333-0-0

Date 18 March 2015)

(Letter of National ISBN Agency No' 4L27lE'slp/03'2015

1st edition Proceeding

Published bY:
Faculty of Pharmacy Universitas Airlangga
Surabaya, lndonesia

Address:
Kampus B Jl. Dharmawangsa Dalam
Surabaya 60286
Phone +62315033710
Fax +62 31 5020514
Website : www.icpps2014.com or wwwff'u na i r'ac'id
Email: icppinfo@gmail.com

rsBN 1?A-t0e-?e333-0-tl

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PREFACE

From Chairman

It is our pleasure to

present you the proceedings of The Lst lnternational Conference on
Pharmaceutics and Pharmaceutical Sciences (ICPPS) organized by The Faculty of Pharmacy

Universitas Airlangga Surabaya lndonesia.
The proceeding was produced based on papers and posters presented at The

1st

lnternational

Conference on Pharmaceutics and Pharmaceutical Sciences (ICPPS), held in Surabaya, lndonesia, 14-

15November2014.
The proceeding clearly reflects broad interest, from the participants that coming from all around the


world.
The papeJ$presented were pharmaceutics and biopharmaceutics; requirements on howto evaluate

molecufp! in discovery and their appropriateness for selection as potential candidate; their
development in context of challenges and benefits, together with associated time and cost
implications and also requirements to progress through pre-clinical and clinical.
ln this an opportunity, lwould like to express my appreciation to the editorialteam of the proceeding
who have been working hard to review manuscripts, and making the first edition of this proceeding
be possible.

I would like also to thanks to all invited speakers and presenters who participated in The 1st
lnternational Conference on Pharmaceutics and Pharmaceutical Sciences (ICPPS) and your
contribution to this proceeding.
Finally, I hope this proceeding will give contribution
Sciences research.

Chairman,

Dra. Esti Hendradi, MSl., Ph.D., Apt


to the Pharmaceutics and Pharmaceutical

COMMITTEE
Advisor
Chairman
Editor

Universitas
: Dean of Faculty of Pharmacy
Ph'D' APt'
: Dra. Esti Hendradi, M'Si"

Airlangga

(Netherlands)

: Dr. Wouter U. Hinrichs
(JaPan)
Prof. Kozo TakaYama


Mutalik (lndia)
or. ttuttakorn Baisaeng {Thailand)
(lndonesia)
Prof. Dr. WidiiSoeratri' DEA

Dr. Srinivas
n
,rtn

Committee:

APt'
Prof. Dr. Widji Soeratri, DEA'
APt'
Prof. Dr. Siswandono, MS''
APt'
Prof .Dr. Tutuk Budiati' MS''

Yuwono' MS'' Apt'


Prof. Dr. rer'nat' Muhammad
APt'
Drs. Hadi Poerwono, MSc''Ph'D'
MSi'' Ph'D' Apt'
Drs. Marcellino Rudyanto'
APt'
Drs. Bambang Widjaja, M'Si'
Drs. SugiYartono, MS, APt'

APt'

Dra.Tutiek Purwanti, MSi'
APt'
Dra.Tristiana Erawati, MSi'
Dra.Retno Sari, MSc, APt'
Dra.Dewi lsadiartuti, MSi' APt'
Dra.Noorma Rosita, MSi' APt'

APt'

Dr. DwiSetyawan, SSi, MSi"

Primaharinastiti' SSi' MSi' Apt'
M'Phil'' Ph'D' Apt'
Dewi MelaniHariyadi' SSi'
APt'
HelmY Yusuf, SSi, MSc'' Ph'D'
AptDwi Lestari' SS|'MPharmSci''
Rrdhani
Dr. rer. nat. wtaria l-ucia
M'Sc' Apt'
tvt"lanny lka Sulistyowati' SFarm'
Apt' - '
Febri Annuryanti, SFarm'M'Sc'
M. Faris Adrianto, MFarm' APt'
Dini Retnowati, SFarm,APt'
Abhimata P, SFarm, APt'

Or.


ni"tt.

TABLE ofCONTENT

Preface from Chairman

Committee
Table of Contents

Author

...... ii

....--..--..--.

................. iii

lndex

.................... iii


AUTHQR INDEX
COMPARISON OF SODIUM STARCH GLYCOLATE AND CROSSCARMELLOSE SODIUM AS
SUPERDISINTEGRANT IN MEFENAMIC ACID FAST DISINTEGRATING TABLET

Adeltrudis Adelsa D, Oktavia Eka Puspita, Amalia Ayuningtyas, Marulita lsadora ,..........,........ 1
STUDY EXPRESSION OF HUMAN ERYTHROPOIETIN EXPRESSSION IN MAMMALIAN CELL
Adi Santoso, Popi Hadiwisnuwardhani, Yana Rubiana, Yulaika Romadhani, Endah Puji
Septisetyani, Dyaningtyas D.P. Putri

ANTIOXIDANT STABILITY ASSAY OF ALPHA TOCOPHERYL ACETATE IN SOL]D LIPlD NANOPARTICLE
SYSTEM (LlPlD BASE BEESWAX AND MONOSTEARIC GLISERYL

50:50)

Anggie Widhi, Noorma Rosita, Widji Soeratri ......................
A BIOACTIVE BOVINE HYDROXYAPATITE4ELATIN IMPLANT FOR IN VITRO GENTAMIC]N RELEASE
..... 13
Aniek Setiya Budiatin, M. Zainuddin, Junaidi Khotib, Diah Himawati
EFFECT OF COMPARISON SURFACTANTAND COSURFACTANT IN WATER/OIL MICROEMULSION IN


OVALBUMIN Microemulsion Water/Oilwith Surfactant (Span 8O-Tween 80) :
C-osurfactant (Ethanol) =5:L,6:!, and 7:1)
................. 18
Anisa Rizki Amalia, Riesta Primaharinastiti, Esti Hendradi ........,......,
RELEASE OF

ANALYSIS OF MYCOLIC ACIDS CLEAVAGE PRODUCT OF

Mycobacterium tuberculosis

CHROMATOGRAPHY-FLAM E IONIZATION DETECTOR

Asri Darmawati, Deby Kusumaningrum, lsnaeni, Muhamad

Zainuddin

PERIPLASMIC EXPRESSION OF GENE ENCODING ANTI-EGFRvIIISINGLE-CHAIN
ANTIBODY USING PelB LEADER SEQUENCE lN ESCHER/CHIA COLI

BY GAS

.............. 21
VARIABLE FRAGMENT

lGrtika Sari Dewi, Debbie Sofie Retnoningrum, Catur Riani, Asrul Muhamad Fuad ................24
IN VIVO ANTIMALARIAL ACTIVIry OF ETHANOL EXTRACT AND ETHYL ACETATE FRACTION OF

Alectryon serrotus LEAVES ON Plasmodium bergheilNFECTED MICE
Aty Widyawaruyanti, Uswatun Khasanah, Lidya Tumewu, Hilkatul llmi, Achmad Fuad Hafid,
Indah S Tantular ...............
..................... 30
PROFILE OF COMMUNIry PHARMACISTS KNOWLEDGE IN PATIENT ASSESSMENT WITH INFLUENZA
SYMPTOMS AND ITS PRODUCTS

Azza Faturrohmah, Arie Sulistyarini, Ana Yuda

...........

..........,........ 33

MoDlFlcArtoNPRocEssoFNATURALCASSAVAsTARcH:THESTUDYoFCHARACIERISTICSAND
M'A'C
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