Effects of dobutamine on ventricular functions and cerebral blood flow in preterm infants with mild hyaline membrane disease

Vol 7, No 4, October - December 1998

Effects of dobutamine on cardiovascular functions in mild

HMD

217

Effects of dobutamine on ventricular functions and cerebral blood flow in
preterm infants with mild hyaline membrane disease
Sudigdo Sastroasmoro

Abstrak
Penelitian ini bertujuan untuk mengetahui status lcardiovaskular pada neonatus kurang bulan (NKB) dengan penyakit membran
hialin (PMH) ringan dan responsnya terhadap pemberian dobutamin. Penelitian dilakukan di RS Dr. Cipto Mangunkusumo, Jakarta,
dari bulanNovember 1997 hinggaMei 1998. NKB dengan PMH rtngan diikutsertakan dalampenelitianbilaberat lahimya>1250 gram
dan usia 60/minute;
(2) intercostal retractions; (3) flaring of the alae nasi;
(4) expiratory grunting; (5) cyanosis at room air.lO
Chest X-ray was done in every patient; a standard
photo was obtained with the patient supine and the

distance of 1 meter from x-ray source. The result was
interpreted by the author and confirmed by a pediatric
radiologist. The radiological criteria were (1) stage I:
reticulo-granular pattern; (2) stage II: air bronchogram; (3) stage III: as stage II but more severe; (4)
stage IV: white lung.r
For the purpose of this study patients with HMD were
classified into 2 categories, i.e., patients with mild
HMD (those who did not require mechanical ventilation), and patients with severe HMD (who required
ventilation). The indication for mechanical ventilation
support for HMD patients were: PaCOz >65 mmHg for
babies >1500 srams or >50 mmHs for babies