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THE
3
rd
REPORT OF THE NATIONAL EYE DATABASE 2009
Age-Related Macular Degeneration Registry 1. Stock and Flow
• A total of 70 patients registered with 112 affected eyes.
2. Patient Demography and Vision
• Mean age was 64.4 years • Mean duration of symptom was 12.9 months
• Proportion of eye with VA 66-612 was 37.9, VA 618-460 was 30.0 and VA 360 or worse was 31.4.
3. Status of AMD
• Half of the eyes had exudative AMD •· Majority of patients present late to the tertiary referral centre.
•· Disciform scar was present in 13 of eyes. •· Only 50 of cases were treatable of which 20 were polypoidal choroidal vasculopathy and 30 were choroidal
neovascularisation. •· Approximately 13 of patients had past history of ischemic heart disease and stroke which shows that majority
of patients do not have contraindications to anti VEGF therapy •· Anti VEGF therapy was the main form of therapy in 45 of cases followed by photodynamic therapy.
•· Only a small number of patients received combination therapy with PDT and anti VEGF in view of the financial constraints.
Retinoblastoma Registry 1. Stock and Flow
• A total of 72 patients registered, of which 11 patient were diagnosed in 2009.
2. Patients Demography •
Mean age at presentation was 2.2 years. · • Youngest age was 3 weeks and the oldest was 10.2 years.
• About a third 34.7 of these patients was in the age group of 13 to 24 months and 23.6 were less than 12 months at presentation.
• More boys 61.1 than girls were affected. • Majority were of Malay ethnicity 62.5, followed by Chinese 13.9 and Indians 9.7.
3. Ocular History and Presentation
• The most common presentation was leukocoria. • Mean duration of disease from onset of symptoms to presentation was 4.1 months with the majority 82.9
within 1 to 6 months. • A total of 96 eyes were affected.
• 30 patients 33.4 had bilateral disease. • 1 patient had positive family history of retinoblastoma.
4. Investigation and Classification
• All patients except one had imaging studies. • In 100 of the studies, there was presence of mass. 94.2 had calcifications.
• 19.8 of the eyes showed evidence of extraocular extension through CT scan, of which the majority involved the optic pathway.
• Two-thirds 62.4 of the patients presented with Group E Retinoblastoma.
5. Management
• 55.6 of patients had systemic chemotherapy with a mean of 8 cycles maximum 15 chemotherapy cycles. •· 63 affected eyes 65.6 were enucleated. 24 eyes 32.2 of the enucleated eyes showed histopathological
extension outside the eyeball. • 5 6.9 patients had external beam radiotherapy.
• 77.8 of eyes had good response with complete regression of tumour. • 5 eyes had progressive disease or recurrence within a year of diagnosis.
CHAPTER 1
CATARACT SURGERY REGISTRY 2009
Contributing Editors
Dr Goh Pik Pin Dr Mohamad Aziz Salowi
Dr Ang Ee Ling
