INTRODUCTION isprs annals III 5 129 2016

REVIEW OF ADVANCES IN COBB ANGLE CALCULATION AND IMAGE-BASED MODELLING TECHNIQUES FOR SPINAL DEFORMITIES V. Giannoglou a, , E. Stylianidis a School of Urban-Regional Planning and Development Engineering, Aristotle University of Thessaloniki, GR 54124 - vgiannoggmail.com a School of Urban-Regional Planning and Development Engineering, Aristotle University of Thessaloniki, GR 54124 - sstylauth.gr Commission V, WG V5 KEY WORDS: Scoliosis, Spine, Cobb angle, X-rays, 3D model, Image based techniques. ABSTRACT: Scoliosis is a 3D deformity of the human spinal column that is caused from the bending of the latter, causing pain, aesthetic and respiratory problems. This internal deformation is reflected in the outer shape of the human back. The golden standard for diagnosis and monitoring of scoliosis is the Cobb angle, which refers to the internal curvature of the trunk. This work is the first part of a post- doctoral research, presenting the most important researches that have been done in the field of scoliosis, concerning its digital visualisation, in order to provide a more precise and robust identification and monitoring of scoliosis. The research is divided in four fields, namely, the X-ray processing, the automatic Cobb angles calculation, the 3D modelling of the spine that provides a more accurate representation of the trunk and the reduction of X-ray radiation exposure throughout the monitoring of scoliosis. Despite the fact that many researchers have been working on the field for the last decade at least, there is no reliable and universal tool to automatically calculate the Cobb angles and successfully perform proper 3D modelling of the spinal column that would assist a more accurate detection and monitoring of scoliosis. Corresponding author

1. INTRODUCTION

Scoliosis is defined as the greater than 10 degrees curvature of the spine, as measured on an X-ray. Anything less is considered to be normal variation. The most common type of scoliosis, idiopathic scoliosis, has no specific identifiable cause so far. Around 2 of the people are diagnosed with scoliosis worldwide, whereas if a family member is diagnosed with scoliosis, other members have percentage as high as 20 to develop scoliosis Department of Orthopaedic Surgery, http:orthosurg.ucsf.edupatient- caredivisionsspineconditionsdeformityscoliosis, which comprises strong evidence that it is inherited. Scoliosis is found at any age, but it is most common in children over 10 years old. Scoliosis can be treated and healed: treatment aims at improving the health and the aesthetics of the patients and it is of paramount importance for the health and self-esteem of juveniles. If the doctor suspects a scoliosis case, after measuring the trunk asymmetry with the scoliometer, an X-ray of the back will be taken, from which the doctor measures the Cobb angle, which is the golden standard to quantify and grade scoliosis. Being manually executed, Cobb angle calculation entails subjectivity, errors and it is time consuming. Considering the severity of scoliosis, authors gathered the most important researches in various fields of the subject, pointing out their strengths and their weaknesses, so that other researchers, as well as the authors themselves, can have a solid ground from where to begin their works. The most reliable means of identifying a scoliotic patient is the X-ray, therefore the initial field of the review is the X-ray processing. With the development of image processing procedures, X-ray images have also been affected, exhibiting some very appealing methodologies to cope with, as it will be explained in more detail later. Another very crucial field in the advances of spinal deformities is the Cobb angle. Being the current golden standard, it is important to be accurately calculated and other researchers strove in finding computerised methodologies to do so as it will be presented in the main part of this work. As the Cobb angle is a 2D measurement of a 3D deformity, it is not the best indicator of the severity manifested in external appearance. The 3D representation of the human spinal column that would successfully depict the real nature of scoliosis is a field that contains tons of work done. To this end, many researchers occupied themselves to develop methodologies for 3D representation of the spine. While all the above mentioned efforts have distinctive characteristics that make them valuable to the scientific community of scoliosis, what is missing is a uniform platform that encompasses all the above features, providing an inclusive tool that is able to perform all the necessary actions spine detection, Cobb angle calculation, 3D model of the spine in order to provide maximum insight for the caretaker of the patient. Authors reckon that a platform like this is the next step based on all the advances that were reviewed in this work. This contribution has been peer-reviewed. The double-blind peer-review was conducted on the basis of the full paper. doi:10.5194isprsannals-III-5-129-2016 129 Since this work is part of a post-doctoral study, the reviewed papers are oriented towards the research goals of the aforementioned study. It is well understood that are plenty more interesting sub-fields in scoliosis subject, but it would be impossible to present all the related studies in a limited space research paper. The rest of the paper is organised as follows: Section 2 is the main part of the present work, including all the paper reviews that comprise the basis of knowledge for the future work. In particular, subsection 2.1 analyses X-ray processing techniques that constitute the first step for detecting spinal deformities in human back. Subsection 2.2 elaborates on the findings concerning Cobb angle detection in literature. Subsection 2.3 deals with the 3D reconstruction of the spinal column techniques and subsection 2.4 focuses on scoliosis assessment techniques that include less or no radiation at all. In section 3 there is a discussion on the findings presented in this paper and also refers to the potential work that could commence from the aforementioned findings.

2. LITERATURE REVIEW