HYPOGLYCEMIC AND ANTIOXIDANT ACTIVITIES OF BALINESE PURPLE SWEET POTATO(IPOMOEA BATATAS L) IN INDUCED DIABETIC RATS.

Contens
Vol. 1 No. 2&3 Jul-Sept & Oct-Dec 2012
1. HYPOGLYCEMIC AND ANTIOXIDANT ACTIVITIES OF BALINESE PURPLE
SWEET POTATO (IPOMOEA BATATASL) IN INDUCED-DIABETIC RATS
I Made Jawi, I Way an Putu Sutirta-Yasa, *Dewa Ngurah Suprapta and Agung Nova Mahendral
2. ETHNOMEDICINAL PLANTS USED BY TRIBALS OF DHAR DISTRICT. MADHYA
PRADESH. INDIA
Kamal Singh Alawa and *Sudip Ray
3. A COMPARATIVE STUDY ON ANTIOXIDANT POTENTIAL OF NINE INDIAN
MEDICINAL PLANTS
Saurabh Acharyya, Amarendra Patra and Prasanta K. Bag
4. ANALYSIS OF EFFLUENT USING PHYSICO-CHEMICAL PARAMETERS AT
PHARMACEUTICAL INDUSTRIES
*Savita Dubey and Deepa Dixit

CIBTech Journal of Pharmaceutical Sciences ISSN: 2319 –3891 (Online)
An Online International Journal Available at http://www.cibtech.org/cjps.htm
2012 Vol. 1 (2-3) Jul.-Sept. & Oct.-Dec., pp.1-6/Suprapta et al.

Research Article

HYPOGLYCEMIC AND ANTIOXIDANT ACTIVITIES OF BALINESE
PURPLE SWEET POTATO (IPOMOEA BATATAS L) IN INDUCEDDIABETIC RATS
1

2 *

3

1

I Made Jawi , I Wayan Putu Sutirta-Yasa , Dewa Ngurah Suprapta and Agung Nova Mahendra
1
2
Department of Pharmacology and Department of Clinical Pathology
Udayana University Denpasar Bali Indonesia
3
Department of Agriculture, Udayana University Denpasar Bali
Indonesia *Author for Correpondence

ABSTRACT

Anthocyanins from plants are potent antioxidants, which may have beneficial effects against oxidative
stress-related diseases, such as diabetes mellitus. Balinese purple sweet potato (Ipomoea batatas L.) is an
anthocyanin-rich food source. This study was aimed to investigate the effect of water extract of Balinese
purple sweet potato on blood glucose level and oxidative stress in diabetic rats. Subject of this study were
20 male adult rats divided into 2 groups with randomized pre-test and post-test control group design.
Blood glucose, malondialdehyde (MDA), and total antioxidant levels of all rats were measured before and
after treatment. After obtaining pre-test data, all of the groups were treated with streptozotocin (STZ) at
40 mg/kg body weight intraperitoneally to induce diabetic condition. Three days later, the treatment group
of rats was treated with 3 ml/day of water extract of purple sweet potato for 60 days. The control group of
rats was given 3 ml of water per day. Blood glucose, MDA, and total antioxidant levels were measured to
obtain post-test data at day 30 and 60. The results showed that in control group, there was a significant
(p