20 be  obvious  external  signs  or  clues. Toxic  and  metabolic  processes  are  unlikely  to  produce
asymmetric deficits. •  hypocalcaemia or hypomagnesaemia
•  meningitis as extension of bacterial pneumonia, i.e. thrombotic meningoencephalitis •  tick fever, especially Babesia bovis
•  grain poisoning can cause staggering and blindness •  poisoning with lubricants, fumigants or exhaust gases
•  polioencephalomalacia from dietary changes
2.10.1 Hypocalcaemia and hypomagnesaemia
In shipboard cattle this is most likely to occur in association with sudden climatic or dietary changes or after long periods of food and water deprivation while being transported or held
in  yards.  Hypocalcaemia  and  hypomagnesaemia  usually  accompany  each  other  to  varying degrees  and  clinical  signs  will  be  related  to  which  is  more  profound.  Rumen  acidosis  from
feeding  batches  of  pellets  with  higher  than  normal  levels  of  fermentable  carbohydrates  is consistently accompanied by hypocalcaemia.
Hypocalcaemic cattle may be seen to be ataxic before becoming recumbent and depressed with  a  dry  nose  and  reduced  rumen  movements.  Simple  hypocalcaemia  is  diagnosed  if
treatment  with  subcutaneous  calcium  injections  leads  to  an  immediate  and  complete recovery.  Hypocalcaemia  complicated  by  indigestion  will  require  other  treatments  to
normalize  rumen  function  such  as  feeding  hay,  lowering  pH  with  sodium  bicarbonate  or administration  of  rumen  fluid  from  a  healthy  animal.  With  hypomagnesaemia,  an  affected
animal  usually  exhibits  hyperexcitability,  convulsions,  falling  on  its  side  with  its  legs alternately extended and relaxed. Death may occur during the convulsions. Frothing at the
mouth  and  profuse  salivation  are  evident.  If  either  disease  is  suspected,  treat  with subcutaneous  administration  of  commercially  available  solutions  that  contain  both  calcium
and magnesium.
2.10.2 Meningitis
Meningitis is usually an extension of bacterial pneumonia, most commonly Histophilus somni formerly  Haemophilus  somnus  ,    but  possibly  Listeria  monocytogenes.  Histophilus  somni
can  cause  an  acute,  often  fatal,  septicaemic  disease  that  can  involve  the  respiratory, cardiovascular,  musculoskeletal,  or  nervous  systems,  either  singly  or  together.  Affected
cattle  are  usually  found  dead  but  may  display  premonitory  nervous  signs  from  thrombotic meningoencephalitis associated with septicaemic episodes.
2.10.3 Tick fever