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  09/01/14 4th ICQG Conference, Edinburgh - 17-22 June 2012.

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   Welcome Welcome to the FourthInternational Conference of Quantitative Genetics:Understanding Variation in Complex Traits - Edinburgh International Conference Centre, 17-22 June 2012 Please clickto download We invite you to join us in the beautiful city of Edinburgh for the Fourth a copy of the Final International Conference of Quantitative Genetics, being held from Programme and Book of

17 – 22 June 2012 at the Edinburgh International Conference Centre. Abstracts

Variation in quantitative and other complex phenotypes underpins most important traits in human health and disease, agriculture, natural populations and evolution. The genomics revolution has provided the tools to start the dissection of such traits, enhancing both their understanding and exploitation. This has led to an explosion of interest and new studies across all of biology. The aim will be to present and discuss state-of-the-art results, theoretical

  09/01/14 4th ICQG Conference, Edinburgh - 17-22 June 2012.

  Edinburgh has the best possible set up for a prestigious conference, and we are confident that the Fourth International Conference of Quantitative Genetics will meet the highest expectations. We look forward to welcoming you to Edinburgh.

  Bill Hill (Chair), On Behalf of the Local Organising Committee.

  

Conference Publicity

We would be extremely grateful if you could assist us in publicising the conference. Please click on these

links to download a . If you wish, please display them in a prominent place in your work place where it can be viewed by people who would find this conference of interest. We would also like to encourage you to use the PowerPoint slide during any presentations you may be giving over the coming year. We thank you in advance for helping us to promote this important conference.

  You may also be interested in the forthcoming conferences: -

  Find us on Follow us on LOCAL ORGANISING COMMITTEE CONFERENCE ORGANISERS • •

  Facebook Twitter Bill Hill (Chair) In Conference Ltd Lutz Bünger 4 – 6 Oak Lane Chris Haley Edinburgh, Mike Kearsey EH12 6XH DJ de Koning Scotland, UK Loeske Kruuk Josephine Pemberton Tel: +44 (0)131 339 9235

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  Alan Wright Fax: + 44 (0)131 339 9798 > E-Mail:

  > >

• INTERNATIONAL ADVISORY COMMITTEE

  David Allison, USA Jonathan Flint, UK Bill Muir, USA David Balding, UK Greg Gibson, USA Patrick Phillips, USA Piter Bijma, Netherlands Mike Goddard, Australia Daniel Pomp, USA Rachel Brem, USA Ary Hoffman, Australia Pak Sham, China Ed Buckler, USA Fred Hospital, France Fred van Eeuwijk, Andrew Clark, USA Mark Lathrop, France Netherlands Mark Daly, USA Trudy Mackay, USA Peter Visscher, Australia Rebecca Doerge, USA Albrecht Melchinger, Germany Bruce Walsh, USA Marie-Anne Felix, France Juha Merilä, Finland Bruce Weir, USA

  

ICQG 2012

_{4th International Conference}

th

  

4 International Conference on

Quantitative Genetics:

Understanding Variation in Complex Traits

  Supported by

Edinburgh, 17 – 22 June 2012

  

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4 International Conference on

  Quantitative Genetics Page

  CONTENTS Welcome/Committees

  2 Information Scientific Programme

  5 Industry Lunchtime Symposia

  13 General Information

  14 Social Programme

  17 Poster Information

  18 Conference Partners, Supporters & Gold Sponsors

  19 Exhibitors and Sponsors

  22 Exhibition Floorplan

  25 Edinburgh City Centre Map

  26 EICC Floorplan

  27 Oral Abstracts

  29 Student Symposia Abstracts

  60 Poster Abstracts

  65 Author Index 261

  Information WELCOME

Welcome to Edinburgh and the Fourth International Conference on Quantitative

Genetics. This is a time of rapid developments towards understanding the genetics of complex

traits and in utilising that knowledge to improve health, food production and the

natural environment. We have continuously improving technology for the collection

and interpretation of molecular and cellular data and new ways to analyse these in

combination with phenotypic data. Yet still we have much to learn and understand

because many key traits are, indeed, very complex. We value this opportunity to

bring you together to exchange ideas, discuss the latest results and consider the new challenges and opportunities.

  Information

We have organised a diverse programme which we hope you will find informative

and stimulating. It was designed to cover most areas from genes to phenotypes,

the molecular to the mathematical, and from the laboratory to farmed and wild

populations. We shall be in plenary session throughout with the aim of maximising

information exchange and interaction of ideas and knowledge across disciplines.

  

We have over 600 delegates registered from over 50 countries. In addition to the

invited and contributed lectures we have around 400 posters to view and discuss,

particularly in the early evening sessions on Monday and Tuesday. There will be

considerable opportunity in the coffee and lunch breaks for further interactions as

we shall be together the whole time in this fine facility, the Edinburgh International

Conference Centre.

  

We hope also that many will participate in the student symposium and subsequent

social activities on Wednesday. Out of hours (only, of course) there is much else to occupy you in the beautiful and compact city of Edinburgh, with restaurants for all tastes and pockets, bars, museums

and historic sights. In addition we start with the Sunday evening mixer and finish

with a banquet at Dynamic Earth.

We very much hope you have an informative, productive and enjoyable time here.

We hope all will go smoothly for you but if you have any problems please let one of us know. With best wishes for a great week. Lutz Bunger, DJ de Koning, Chris Haley, Bill Hill, Mike Kearsey, Loeske Kruuk,

Josephine Pemberton and Alan Wright (Organising Committee), Kay Boulton (PG

Symposium)

  th

4 International Conference on

  Quantitative Genetics Conference Organisers

  ICQG Secretariat c/o In Conference Ltd, 4-6 Oak Lane, Edinburgh, EH12 6XH, Scotland, UK Tel: +44 (0)131 339 9235 Fax: +44 (0)131 339 9798 Email: icqg4@in-conference.org.uk

  Information COMMITTEES LOCAL ORGANISING COMMITTEE Bill Hill (Chair) Lutz Bünger Chris Haley Mike Kearsey DJ de Koning Loeske Kruuk Josephine Pemberton Alan Wright Kay Boulton (PG Symposium)

INTERNATIONAL ADVISORY COMMITTEE

  David Allison, USA Mark Lathrop, France David Balding, UK Trudy Mackay, USA Piter Bijma, Netherlands Albrecht Melchinger, Germany Rachel Brem, USA Juha Merilä, Finland Ed Buckler, USA Bill Muir, USA Andrew Clark, USA Patrick Phillips, USA Mark Daly, USA Daniel Pomp, USA Rebecca Doerge, USA Pak Sham, China Marie-Anne Felix, France Fred van Eeuwijk, Netherlands Jonathan Flint, UK Peter Visscher, Australia Greg Gibson, USA Bruce Walsh, USA Mike Goddard, Australia Bruce Weir, USA Ary Hoffman, Australia Qifa Zhang, China Fred Hospital, France

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  4 ^th International Conference on

  Eric Lander (Broad Institute of MIT & Harvard, USA) 12.40 –

  Chair: Bruce Walsh (University of Arizona, USA)

  O-3

An improved method for heritability estimation provides insights into the genetic

architecture of epilepsy

  Doug Speed (University College London, UK)

  11.40 –

  12.40 Genetics Society Mendel Lecture

  Chair: Veronica van Heyningen (President, Genetics Society)

  O-4 Secrets of the human genome

  13.40 Lunch

  11.10 –

  13.40 -

  15.20 Session 2 Evolutionary quantitative genetics

  Chair: Derek Roff ( University of California Riverside, USA) 13.40 –

  14.20 O-5

  Evolution of genetic variance under selection

  Mark Blows (University of Queensland, Australia) 14.20 –

  14.40 O-6

  

Plants in heterogeneous environments: determining when phenotypic plasticity is

adaptive

  11.40 The genetic architecture of quantitative traits

  11.10 Tea/Coffee

  Quantitative Genetics Information SCIENTIFIC PROGRAMME

  09.05 -

  Sunday 17th June

  14.00 –

  19.30 Registration Open 18.00 –

  19.30 Welcome Reception Cromdale Hall, EICC

  Monday 18th June

  08.00 –

  19.30 Registration Open 09.00 –

  09.05 Welcome from Bill Hill, Chair, Local Organising Committee

  10.40 Session 1 The genetic architecture of quantitative traits

  Ed Buckler (USDA, Ithaca) 10.40 –

  Chair: Bruce Walsh (University of Arizona, USA) 09.05 –

  09.20 Introduction: The quantitative genetics landscape in 2012 Bruce Walsh

  09.20 –

  10.00 O-1

  From Galton to GWAS: genetics of quantitative traits in human populations

  Peter Visscher (University of Queensland, Australia) 10.00 -

  10.40 O-2

  Uniting the world’s maize diversity for dissection of complex traits and accelerated breeding

  Diane Byers (Illinois State University, USA)

  Information Information Monday 18th June

  O-14 Population genetics revealed by enormous structural variations discovered by population-scale sequencing

  10.40 Session 3 Variation in the genome

  Chair: Alan Archibald (Roslin Institute, University of Edinburgh, UK) 09.00 –

  09.40 O-12

  Causes and consequences of new mutations

  Matt Hurles (Sanger Institute, UK) 09.40 –

  10.00 O-13

  The role of genetic variations on gene expression and splicing in multiple regions of control in human post-mortem brain tissue

  Daniah Trabzuni (University College London, UK & King Faisal Specialist Hospital, Saudi Arabia)

  10.00 – 10.20:

  Quan Long (Gregor Mendel Institute, Austria) 10.20 –

  19.30 Registration Open

  10.40 O-15

  Variation in transcription factor binding among humans

  Maya Kasowski (Yale University, USA) 10.40 –

  11.10 Tea/Coffee

  11.10 -

  12.40 Variation in the genome

  Chair: Alan Archibald (Roslin Institute, University of Edinburgh, UK) 11.10 –

  11.50 O-16

  Mapping the epigenetic basis of complex traits in Arabidopsis

  09.00 -

  08.00 –

  14.40 –

  Chair: Derek Roff (University of California, USA) 15.50 –

  15.00 O-7

  Discovery of cryptic genetic variation in C. elegans embryogenesis

  Annalise Paaby (New York University, USA) 15.00 –

  15.20 O-8

  Genomic comparisons between selected and relaxed chicken lines

  Mats Pettersson (Swedish University of Agricultural Sciences, Sweden) 15.20 –

  15.50 Tea/Coffee

  15.50 -

  17.20 Evolutionary quantitative genetics

  16.30 O-9

  Tuesday 19th June

  Gene interactions underlying the evolution of complex traits

  Patrick Phillips (University of Oregon, USA) 16.30 –

  17.00 O-10

  What, me natural? Patterns of selection in wild systems and their theoretical implications

  Jarrod Hadfield (Universities of Edinburgh and Oxford, UK) 17.00 –

  17.20 O-11

  The deceit of monogamy: Quantitative genetic insights into the evolutionary ecology of polyandry in the wild

  Jane Reid (University of Aberdeen,UK) 17.30 –

  19.30 Poster Session 1 – Odd numbered posters

  Frank Johannes (University of Groningen, The Netherlands)

  4 ^th International Conference on

  Chair: David Balding (University College London, UK) 15.50 –

  Daniel Runcie (Duke University, USA) 15.00 –

  15.20 O-22

  Big data, small cost – combining low-pass genome sequencing with long-range phasing and haplotype library imputation to create more powerful data for genomic prediction in plants and animals

  John Hickey (University of New England, Australia) 15.20 –

  15.50 Tea/Coffee

  15.50 -

  17.20 Advances from numerical methods

  16.30 O-23

  15.00 O-21

  Haplotype phasing using next-generation sequencing reads

  Jonathan Marchini (University of Oxford, UK) 16.30 –

  17.00 O-24

  Whole-genome regression and prediction of human complex traits using data from related and unrelated individuals

  Gustavo de los Campos (University of Alabama, USA) 17.00 –

  17.20 O-25

  Relaxing the genetic model to identify quantitative trait loci having heterogeneous effects

  Hugues Aschard (Harvard University, USA) 17.20 –

  Sparse factor models for estimating the genetic architecture of gene expression traits

  Jean-Michel Elsen (INRA, France) 14.40 –

  Quantitative Genetics Information Tuesday 19th June

  13.40 Lunch/Exhibition/Poster viewing

  11.50 –

  12.20 O-17

  The role of tandem repeats in mRNA and protein expression homeostasis

  Sreenivas Chavali (MRC Lab Molecular Biology, UK) 12.20 –

  12.40 O-18

  Dissecting the contribution of regulatory sequence variation to quantitative haematological traits using maps of open chromatin in primary human blood cells

  Cornelis Albers (University of Cambridge & Sanger Institute, UK) 12.40 –

  Affymetrix Lunchtime Symposium: How can you accelerate your genomics program from discovery to results?

  CLIP Test: a new fast and simple method to distinguish between linked or pleiotropic quantitative trait loci in linkage disequilibrium analysis

  Professor David W. Burt, Chair of Comparative Genomics (The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, UK)

  13.40 -

  15.20 Session 4 Advances from numerical methods

  Chair: David Balding (University College London, UK) 13.40 –

  14.20 O-19

  

Statistical methods for the genetic analysis of arbitrarily structured populations

  John Storey (Princeton University, USA) 14.20 –

  14.40 O-20

  19.30 Poster Session 2 – Even numbered posters

  Information Information Wednesday 20th June 08.00 –

  Matthew Horton (University of Chicago, USA) 10.40 –

  Whole genome sequence analysis of a large Scottish family with bipolar disorder

  12.40 O-32

  Greg Gibson (Georgia Tech, USA) 12.20 –

  Integrating gene expression into predictive health genomics

  12.20 O-31

  Richard Durbin (Sanger Institute, UK) 11.50 –

  Quantitative association genetics of high dimensional cellular traits: extending beyond expression QTLs

  11.50 O-30

  Chair: Marie-Anne Felix, (École Normale Supérieure, Paris, France) 11.10 –

  12.40 Technical advances and emerging areas

  11.10 -

  11.10 Tea/Coffee

  How do hosts shape their microbial communities?

  16.00 Registration Open 09.00 -

  10.40 O-29

  Debby Lipschutz-Powell (Roslin Institute, University of Edinburgh, UK) 10.20 –

  The relationship between binary disease status and underlying heterogeneity in susceptibility and infectivity

  10.20 O-28

  Lachlan Coin (BGI Shenzhen, China & Imperial College London, UK) 10.00 –

  Low depth, whole genome sequencing of Dai population demonstrates superiority over use of whole genome genotyping arrays in uncovering population structure, demographic history, selective pressures and phenotype associations in non-european populations

  10.00 O-27

  Sebastian Zöllner (University of Michigan, USA) 09.40 –

  Rare variant patterns in 14,000 human samples and lessons for study design

  09.40 O-26

  Chair: Marie-Anne Felix, (École Normale Supérieure, Paris, France) 09.00 –

  10.40 Session 5 Technical advances and emerging areas

  Kathryn Evans (University of Edinburgh, UK)

  4 ^th International Conference on

  Chair: Michel Georges (University of Liege, Belgium) 09.00 –

  15.50 SO- 7 / P-79

  Maternal genetic effects set the potential for evolution in red squirrels

  S.E. McFarlane (University of Guelph, Canada)

  15.50 Concluding Remarks 20.00 – Midnight

  Genetics Society Postgraduate Symposium Ceilidh Thursday 21st June

  08.00 –

  17.30 Registration Open

  09.00 -

  09.40 O-33

  Direct and indirect genetic effects for survival in purebred and crossbred laying hens

  Charting the genotype-phenotype map: lessons from Drosophila

  Trudy Mackay (North Carolina State University, USA) 09.40 –

  10.00 O-34

  

Heterosis as a systemic property emerging from the non-linearity of the genotype-

phenotype relationship: evidence from metabolic models and test-tube genetics

  Dominique de Vienne (University Paris XI, France) 10.00 –

  10.20 O-35

  Discovering early and late regulators of haematopoiesis through large-scale genomic analyses

  Nicole Soranzo (Sanger Institute, UK)

  Katrijn Peeters (Wageningen University, The Netherlands) 15.35 –

  15.35 SO-6 / P-214

  Quantitative Genetics Information Wednesday 20th June

  14.35 SO-2 / P-46

  14.00 –

  16.10 Genetics Society Postgraduate Symposium 14.00 –

  14.05 Welcome Kay Boulton (University of Edinburgh, UK)

  14.05 –

  14.20 SO-1 / P-43

  Markers as traits in multivariate BLUP: using REML for association testing and integration with breeding value prediction

  Jeremy Brawner (Commonwealth Scientific and Industrial Research Organisation, Australia)

  14.20 –

  Genetic markers as instruments for Mendelian randomization studies on vitamin D

  Roseann Peterson (Virginia Commonwealth University, USA) 15.20 –

  Diane Berry (University College London, UK) 14.35 –

  14.50 SO-3 / P-41

  

Using KEGG pathways and expression studies and stuff for genomic partitioning

  Stefan M. Høj-Edwards (Aarhus University, Denmark) 14.50 –

  15.05 SO-4 / P-283

  Genetic interactions in the human liver

  Darren J. Fitzpatrick (University College Dublin, Ireland) 15.05 –

  15.20 SO-5 / P-265

  Evidence of shared polygenic risk among smoking behaviors and body composition

10.40 Session 6 Bridging the genotype-phenotype gap

  Information Information Thursday 21st June

  Gibran Hemani (Roslin Institute, University of Edinburgh, UK & University of Queensland, Australia)

  Chair: Bruce Weir (University of Washington, USA) 13.40 –

  14.20 The Genetics Society Balfour Lecture

  O-40 Variance controlling genes and their role in the genetic architecture of complex traits

  Orjan Carlborg (Swedish University of Agricultural Sciences, Sweden) 14.20 –

  14.40 O-41

  GWAS: 2D, or not 2D: that is the question

  14.40 –

  13.40 -

  15.00 O-42

  Knowledge-driven analysis identified a gene-gene interaction affecting high-density lipoprotein cholesterol levels in multi-ethnic populations

  Alon Keinan (Cornell University, USA) 15.00 –

  15.20 O-43

  The genetic architecture of quantitative traits: lessons from biochemical markers for disease

  Beben Benyamin (University of Queensland, Australia) 15.20 –

  15.20 Session 7 The genetic architecture of quantitative traits 2

  13.40 Lunch/Exhibition/Poster viewing

  10.20 –

  Chair: Michel Georges (University of Liege, Belgium) 11.10 –

  10.40 O-36

  A sexual ornament in chickens is determined by pleiotropic alleles at HAO1 and BMP2, selected during domestication

  Dominic Wright (Linköping University, Sweden) 10.40 –

  11.10 Tea/Coffee Sponsored by Nature Communications

  11.10 -

  12.40 Bridging the genotype-phenotype gap

  11.50 O-37

  Michael Magwire (North Carolina State University, USA) 12.40 –

  Diamonds in the dirt: biological and translational insights into type 2 diabetes from large-scale genetic studies

  Mark McCarthy (University of Oxford, UK) 11.50 –

  12.20 O-38

  The biologic relevance of eQTLs: a genome wide confirmation of eQTLs using two types of inbred populations in C. elegans

  Mark Sterken (Wageningen University, The Netherlands) 12.20 –

  12.40 O-39

  Quantitative genetics of Drosophila life span

  15.50 Tea/Coffee Sponsored by Nature Communications

  4 ^th International Conference on

  Chair: Albrecht Melchinger (University of Hohenheim, Germany) 11.10 –

  Rong-Cai Yang (University of Alberta, Canada) 10.20 –

  10.40 O-50

  Applying quantitative genetics to epidemics and disease resistance: implications of dynamic and noisy data

  Steve Bishop (Roslin Institute and R(D)SVS, UK) 10.40 –

  11.10 Tea/Coffee

  11.10 -

  12.40 Interactions among individuals and with the environment

  11.50 O-51

  10.20 O-49

  The consequences of indirect genetic effects for heritable variation and response to selection

  Piter Bijma (Wageningen University, The Netherlands) 11.50 –

  12.20 O-52

  The genetics of social dominance: does competition cause constraint?

  Alastair Wilson (University of Edinburgh, UK) 12.20 –

  12.40 O-53

  Simple and effective methods of addressing competitive effects in animal breeding programs

  William Muir (Purdue University, USA) 12.40 –

  Nonlinear genotype x environment interaction

  Jun Zhu (Zhejiang University, China) 10.00 –

  Quantitative Genetics Information Thursday 21st June 15.50 -

  The quantitative genetics of phenotypic robustness

  17.20 The genetic architecture of quantitative traits 2

  Chair: Bruce Weir (University of Washington, USA) 15.50 – 16.30:

  O-44 From Castle to the Collaborative Cross: evolution of the mouse in quantitative genetics research

  Daniel Pomp (University of North Carolina, USA) 16.30 –

  17.00 O-45

  Genetic architecture and evolution of quantitative traits

  Mike Goddard (University of Melbourne, Australia) 17.00 –

  17.20 O-46

  Hunter Fraser (Stanford University, USA)

  Novel methods of GWAS for mapping genes of complex traits and their applications in crop breeding

  Friday 22nd June 08.00 –

  17.30 Registration Open 09.00 -

  10.40 Session 8 Interactions among individuals and with the environment

  Chair: Albrecht Melchinger (University of Hohenheim, Germany) 09.00 –

  09.40 O-47

  Studying the genotype-phenotype map in Arabidopsis

  Magnus Nordborg (Gregor Mendel Institute, Austria) 09.40 –

  10.00 O-48

  13.40 Lunch/Exhibition/Poster viewing

  Information Information Friday 22nd June 13.40 -

  15.50 -

  19.30 – Midnight Banquet at Dynamic Earth

  17.30 Close of Conference - Thanks

  Isobel Stewart (MRC Human Genetics & University of Edinburgh, UK) 17.20 –

  Genomic prediction of colorectal cancer risk using GBLUP

  17.20 O-60

  Chris-Carolin Schoen (Technical University Munich, Germany) 17.00 –

  Genome-based prediction in highly structured plant populations

  17.00 O-59

  Pak Sham (The University of Hong Kong, Hong Kong) 16.30 –

  

Predicting disease risk from marker genotypes under a polygenic model

  16.30 O-58

  Chair: Theo Meuwissen (Norwegian University of Life Science, Norway) 15.50 –

  17.30 Genomic information in prediction

  15.50 Tea/Coffee

  15.20 Session9 Genomic information in prediction

  David Habier (Iowa State University, USA) 15.20 –

  Genomic-BLUP decoded: a look into the black box

  15.20 O-57

  Jose Crossa (International Maize and Wheat Improvement Center, Mexico) 15.00 –

  Next generation breeding using genotyping-by-sequencing

  15.00 O-56

  Ulrike Ober (Georg-August-University Göttingen, Germany) 14.40 –

  Using whole genome sequence data to predict quantitative trait phenotypes in Drosophila melanogaster

  14.40 O-55

  Ben Hayes (Victorian Department of Primary Industries, Australia) 14.20 –

  Towards genomic prediction from genome sequence data and the 1000 bull genomes project

  14.20 O-54

  Chair: Theo Meuwissen (Norwegian University of Life Science, Norway) 13.40 –

  Tickets must have been pre-booked

  th

4 International Conference on

  Quantitative Genetics

  INDUSTRY LUNCHTIME SYMPOSIUM Affymetrix Lunchtime Symposium _th Tuesday 19 June 12.55 – 12.25 Lomond Suite, located on the ground floor level of the Conference Centre Information Bagged lunches will be available for collection to be taken into the Lomond Suite for the lunchtime symposium.

  How can you accelerate your genomics program from discovery to results? Abstract: With so many genomics technologies available, knowing how to integrate them for maximum efficiency can be challenging. This is true whether the objective is to dissect complex traits, identify disease genes or improve breeding. The prevailing strategy is to integrate NGS and other technologies to quickly progress genomic markers from discovery into downstream studies and applications. For mid to high density marker sets, microarrays are widely preferred due to the high data quality, throughput, analytical efficiency and cost effectiveness they offer. Taking genomics in the chicken as an example, this scientific seminar will discuss best practice that is equally relevant across diverse species and applications.

  Invited presentation: Development and characterization of a high-density SNP genotyping assay for the chicken Professor David W. Burt, Chair of Comparative Genomics, The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh

  Information GENERAL INFORMATION Registration/Information Desks All delegates will receive their name badge, meeting documents, ordered tickets and all relevant conference information upon arrival at the Conference Centre. The Registration and Information Desks will be open at the following times: th

  Sunday 17 June 14.00 – 19.30 th

  Monday 18 June 08.00 – 19.30 th

  Tuesday 19 June 08.00 – 19.30 th

  Wednesday 20 June 08.00 – 16.00 Information st

  Thursday 21 June 08.00 – 17.30 nd

  Friday 22 June 08.00 – 17.30 Exhibition Opening Hours th

  Sunday 17 June 18.00 – 19.30 th

  Monday 18 June 08.00 – 19.30 th

  Tuesday 19 June 08.00 – 19.30 th

  Wednesday 20 June 08.00 – 16.00 st

  Thursday 21 June 08.00 – 17.30 nd

  Friday 22 June 08.00 – 15.50 Tea/Coffee Breaks and Lunch Arrangements

Catering points will be located with the exhibition in the Cromdale Hall which is

located on the lower level of the Conference Centre.

On Tuesday lunchtime there will also be secondary catering points on the ground

level of the Strathblane Hall for those attending the lunchtime symposium. Please

follow the directions of the staff at the Conference Centre. If you have requested a special diet at the time of registering (other than vegetarian), then your name badge will have a sticker on the back which you should show to the catering staff who will bring you your pre-ordered food. Thank you to Nature Communications who have sponsored the tea and coffee breaks on Thursday.

  th

4 International Conference on

  Quantitative Genetics Congress Etiquette Delegates are advised that they are not allowed to take photographs of any posters or presentations without the author’s/presenter’s consent. Delegates should also obtain consent from an author before citing any of their work that was presented at the conference. If you intend to ‘blog’ or ‘twitter’ results from this conference you must inform the conference organisers in advance and get the permission of the author or presenter.

  Information Mobile phones should be switched off or placed on ‘silent’ during sessions. Thank you for your co-operation.

  WiFi Access The conference is providing WiFi access free to delegates who have their own laptops. Please see the registration notice board for password and log in details.

  Please note that there are printing facilities in the Business Centre although this will be chargeable to delegates. Thank you to Genetics Society of America Journals (GENETICS and G3) who have sponsored the WiFi.

  Certificate of Attendance A certificate of attendance will be emailed to all participants following the conference.

  Speaker Preview Room This is located in Harris Room 1, on the first floor. All presenters are required to check in their presentation a minimum of 4 hours prior to their talk.

  The Speaker Preview Room will be open at the following times: th

  Sunday 17 June 14.00 – 19.30 th

  Monday 18 June 08.00 – 17.30 th

  Tuesday 19 June 08.00 – 17.30 th

  Wednesday 20 June 08.00 – 16.00 st

  Thursday 21 June 08.00 – 17.30 nd

  Friday 22 June 08.00 – 15.50

  Information Insurance The Conference Organisers cannot accept any liability for personal injuries or for loss or damage to property belonging to delegates, either during, or as a result of the conference. Please check the validity of your own personal insurance before travelling.

  Security

Your name badge must be worn at all times otherwise you will not be allowed entry

to the conference centre. Exhibitor staff do not have access to the scientific sessions.

  

Please leave any luggage or poster tubes with the staff at the cloakroom. This will

be manned during the normal opening hours of the conference.

  Information Social Programme Welcome Reception _th Sunday 17 June 18.00 – 19.30 Cromdale Hall, Edinburgh International Conference Centre

The Welcome Reception will take place at the Edinburgh International Conference

Centre. The cost for this event is included in the registration fee.

  Genetics Society Postgraduate Symposium Ceilidh Wednesday 20th June 20.00 – Midnight Edinburgh International Conference Centre A Ceilidh will take place at the Edinburgh International Conference Centre following

the Genetics Society Postgraduate Symposium. The cost for this event is £5 and

tickets can be purchased at the registration desk. All delegates are welcome to attend. Please note there will be no food served at this event and a cash bar will be available.

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4 International Conference on

  Quantitative Genetics Conference Dinner _nd Friday 22 June 19.30 – Midnight

  Dynamic Earth, 112-116 Holyrood Road, Edinburgh, EH8 8AS The conference dinner will be held at Dynamic Earth on Friday evening.

  The evening will start with a pre-dinner drinks reception, followed by dinner and dancing. Offering stunning 360 degree views across Edinburgh’s picturesque cityscape and

  Information Royal Park, the five star Our Dynamic Earth is a perfectly situated venue with a unique heritage twist. Located at the bottom of Holyrood Road, neighbouring the Scottish Parliament and the Palace of Holyrood House, getting to Our Dynamic Earth is easy and is approximately a 5 minute taxi ride from the EICC.

  Tickets cost £50.00 and must have been pre-booked at the time of registration. Should you wish to attend and have not purchased a ticket please speak to the staff at the registration desk.

  Limited shuttle buses will be available from 10.30pm – Midnight stopping at North Bridge, mid George Street, West End and the EICC. Drop point

  Drop point DYNAMIC EARTH Drop point

• EICC

  Information Poster Information Posters All posters will be on display for the duration of the conference, however, there are two designated poster sessions to enable delegates to discuss the author’s work in more detail. We ask that you stand by your board during your allocated poster sessions so that delegates can ask you questions about your work.

  Poster Session 1 Poster Session 2 th th

  Monday 18 June Tuesday 19 June 17.30 – 19.30 17.20 – 19.30 Information

  Sponsored by

• Posters ending in an Odd-number: • Posters ending in an Even-number: Stand by your board from 17.30 to Stand by board from 17.20 – 19.30

19.30 All posters are to be displayed from 18:00 Sunday and must be removed by 15:50 on Friday.

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  Quantitative Genetics Conference Supporters The Genetics Society Contact: Linda Allardyce or Ivvah Chung The Genetics Society, c/o Portland Customer Services, Commerce Way, Colchester CO2 8HP Tel: +44 (0)1206 796 351 / Fax: +44 (0)1206 799 331

  Information Email: theteam@genetics.org.uk Website:www.genetics.org.uk The Genetics Society was founded by William Bateson in 1919 and is one of the oldest “learned societies” devoted to genetics in the world. Its membership of over 1700 comprises the UK’s active geneticists, including academics, researchers and students.

  The Genetics Society organises meetings to promulgate genetics, supports students to attend meetings, sponsors research through fieldwork grants and student bursaries, and promotes the Public Understanding of Genetics. It co-owns two leading journals in the field: Heredity and Genes and Development. th

  The Genetics Society is proud to be the major sponsor of the 4 International Conference on Quantitative Genetics.

UNIVERSITY OF EDINBURGH

  The University of Edinburgh, Old College, South Bridge, Edinburgh EH8 9YL www.ed.ac.uk The University is home to a vigorous complex trait genetics research community.

  There are particular strengths in this area in biomedical, evolutionary and livestock genetics. We welcome approaches from anyone interested in the many exciting opportunities available for research and education at all levels from MSc to senior scientist.

  Information

SCOTTISH AGRICULTURAL COLLEGE

  www.sac.ac.uk Communications Unit SAC, King’s Buildings, West Mains Road, Edinburgh, EH9 3JG Tel: 0131 535 4000

Over the past decade we have seen agriculture move from being regarded as a

‘sunset ‘industry to one that is now core to contemporary political and societal

thinking. Our food supplies, our environment, our water quality, and our renewable

energy capability, all depend on the effective and efficient management of our land

resources. SAC’s portfolio of expertise in research, in teaching and in consultancy, is

being increasingly recognised as a core national and international resource that is

  Information competent to tackle many of these issues. Gold Sponsor The EW Group: Aqua Gen AS, Aviagen, Hy-Line and Lohmann Tierzucht. Aqua Gen AS Aqua Gen AS, PO Box 1240, Sluppen, N-7462 Trondheim Phone: +47 72 45 05 00 Fax: +47 73 54 62 91 E-mail: firmapost@aquagen.no Web: www.aquagen.no

Aqua Gen manages and further develops the world’s first family-based breeding

programs of Atlantic salmon and rainbow trout. Today’s eggs from the Aqua Gen

strain are selected for excellent performances on growth, disease resistance, robustness and filet quality by use of state-of-the art methods within quantitative and molecular genetics.

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4 International Conference on

  Quantitative Genetics Aviagen Newbridge, Midlothian, EH28 8SZ, Scotland, UK Tel: +44 131 333 1056 Fax: +44 131 333 3296 Email: infoworldwide@aviagen.com www.aviagen.com Aviagen is the world’s leading poultry breeding company, developing pedigree

  Information lines for the production of broiler chickens and turkeys under the Ross, Arbor Acres, Indian River, B.U.T. and Nicholas brand names. Aviagen has wholly-owned operations on five continents, employs almost 3,000 people and a distribution network that serves customers in 120 countries.

  Hy-Line Contact: Jerry Dreyer Hy-Line International, PO Box 310, Dallas Center IA 50063 USA Tel: +1-515-992-3736 Email: jdreyer@hyline.com www.hyline.com Hy-Line International is the world’s oldest egg layer genetics company since being founded by the Wallace family as part of Pioneer Seed Corn in 1936. Hy-Line layers have become the largest selling layers across the globe and are known for their superior livability, feed conversion and egg quality.

  LOHMANN TIERZUCHT GmbH Am Seedeich 9 – 11, 27472 Cuxhaven Phone: +49 4721 505 0 Fax: +49 4721 505 222 E-Mail: info@ltz.de LOHMANN TIERZUCHT – Breeding for success … together! LOHMANN TIERZUCHT is the specialist for layer breeding and as a worldwide leader in the market constantly improving the performance characteristics. The diagnostics conducted at LOHMANN’s veterinary laboratory and the resulting curative measures round up the range of products.

  Information Exhibitors AFFYMETRIX Mercury Park, Wycombe Lane, Wooburn Green, HP10 0HH, United Kingdom Tel: +44 (0)1628 552500 Email: Sales_Europe@affymetrix.com Website: www.affymetrix.com

  ® Affymetrix , part of The Genome Generation, provides genomic solutions for

agrigenomics and human health research. Our technologies for whole-genome

  Information

analysis to single-gene validation enable sequencing discoveries to be confirmed

and applied. Our solutions for expression, genotyping and cytogenetics enable your translational and applied research… we are all The Genome Generation.

BIOCOMPUTING PLATFORMS LTD

  Elina Lamponen BC Platforms Ltd., Innopoli 2, Tekniikantie 14, Espoo, FI-02150, Finland Tel: +358 9 2517 7340 Fax: +358 10 296 1288 Email: elina.lamponen@bcplatforms.com BC Platforms offers data management solutions for genetic researchers. Our systems

include SNP genotyping for GWAS, next-generation sequencing, CNV, MultiQTL,