FS29 PRE IMPLANTATION GENETIC DIAGNOSIS PGD
Fa t Sheet 29 | PRE-IMPLANTATION GENETIC DIAGNOSIS PGD
This Fa t Sheet des i es a p e-p eg a y tesi g opio alled p e-i pla taio ge ei diag osis PGD .
With the use of i itro fe ilisaio IVF , PGD is a diag osi test pe fo ed o a e
yo p io to
i pla taio i the ute us.
I su
ary
PGD i ol es tesi g for ertai ge ei o diio s i a e ryo reated usi g in vitro
ferilisaio IVF prior to tra sferri g it to the uterus a d allo i g it to de elop or ally
O ly those e ryos that do ot ha e the spe ii ge ei
e tra sferred i to the o a ’s uterus
I Australia, PGD is urre tly o ly ofered i the pri ate health sei g.
WHAT IS PRE-IMPLANTATION GENETIC
DIAGNOSIS PGD ?
P e-i pla taio ge ei diag osis PGD is a
te h i ue that is u e tly o ly a aila le i the
p i ate sei g. It is a e y spe ialised te h i ue
that a help ouples ho a e at i eased isk of
ha i g a hild ith a ge ei o diio a oid doi g
so ithout the eed fo de isio s ega di g
te i aio of a afe ted p eg a y.
PGD i ol es tesi g a e
yo that has ee
eated usi g i itro fe ilisaio IVF , p io to
t a sfe i g it to the ute us a d allo i g it to
de elop o ally.
Figure 9. : The PGD pro ess. I so e la oratories, the e
re o ed fro the lasto yst, rather tha the lasto ere
o diio that as tested for ill
HOW IS PGD PERFORMED?
Ho o es a e gi e to the o a to si ulate
he o a ies a d e a le the olle io of a u e
of eggs alled oo ytes . Ate the eggs a e
e o ed, the eggs a e fe ilised i the la o ato y
ith spe . Those eggs that a e su essfully
fe ilised di ide a d uliply to fo a de elopi g
e
yo alled a lasto e e. Ate th ee to i e
days, o e o t o ells a e e o ed i o de to test
fo the spe ii ge ei o diio i uesio . The
e o al of these ells does ot appea to ha
the de elopi g e
yo Figure 9. .
O ly those e
yos that do ot ha e the spe ii
ge ei o diio tested fo
ill e t a sfe ed
i to the o a ’s ute us.
ryo is allo ed to gro
.ge ei s.edu.au
for up to i e days so that ells are
Updated
Page of
Septe e
5
Fa t Sheet 29 | PRE-IMPLANTATION GENETIC DIAGNOSIS PGD
Usually, o
o e tha o e e
yo ill e
t a sfe ed to the ute us at a y o e i e to a oid
the possi ility of uliple i ths.
of the IVF p o edu e follo ed y PGD ith that of
te i aio of a afe ted hild o ei ed
atu ally.
I so e IVF u its, u afe ted e
yos that a e
ot used a
e f oze fo t a sfe i a othe
y le.
Fo ouples ith a o al o eligious o je io to
p eg a y te i aio a d ho also ha e a isk
of ha i g a hild ith a ge ei o diio , this
te h i ue ay p o ide the oppo tu ity to ha e
a u afe ted hild.
WHAT ARE THE ADVANTAGES AND
DISADVANTAGES OF PGD?
Su ess ates fo ha i g a hild f o a IVF y le
follo ed y PGD a y f o IVF e t e to e t e
ut te d to follo sta da d IVF su ess ates.
The efo e a p eg a y a d a u afe ted hild
a ot e gua a teed usi g this te h i ue
Like a y IVF p o edu e, st ess a d ote
disappoi t e t a a o pa y PGD. Couples ill
eed to ala e the i a ial a d e oio al ost
I othe s, PGD ay e a p efe ed opio o e
p e atal tesi g i
a
atu ally o ei ed
p eg a y. It a also eli i ate the possi ility of
epeated is a iages fo ouples he e o e
pa t e a ies a h o oso al t a slo aio .
I Aust alia, PGD is u e tly o ly ofe ed i the
p i ate sei g. Ge ei ou selli g is i po ta t
efo e o side i g PGD.
.ge ei s.edu.au
Updated
Page of
Septe e
5
This Fa t Sheet des i es a p e-p eg a y tesi g opio alled p e-i pla taio ge ei diag osis PGD .
With the use of i itro fe ilisaio IVF , PGD is a diag osi test pe fo ed o a e
yo p io to
i pla taio i the ute us.
I su
ary
PGD i ol es tesi g for ertai ge ei o diio s i a e ryo reated usi g in vitro
ferilisaio IVF prior to tra sferri g it to the uterus a d allo i g it to de elop or ally
O ly those e ryos that do ot ha e the spe ii ge ei
e tra sferred i to the o a ’s uterus
I Australia, PGD is urre tly o ly ofered i the pri ate health sei g.
WHAT IS PRE-IMPLANTATION GENETIC
DIAGNOSIS PGD ?
P e-i pla taio ge ei diag osis PGD is a
te h i ue that is u e tly o ly a aila le i the
p i ate sei g. It is a e y spe ialised te h i ue
that a help ouples ho a e at i eased isk of
ha i g a hild ith a ge ei o diio a oid doi g
so ithout the eed fo de isio s ega di g
te i aio of a afe ted p eg a y.
PGD i ol es tesi g a e
yo that has ee
eated usi g i itro fe ilisaio IVF , p io to
t a sfe i g it to the ute us a d allo i g it to
de elop o ally.
Figure 9. : The PGD pro ess. I so e la oratories, the e
re o ed fro the lasto yst, rather tha the lasto ere
o diio that as tested for ill
HOW IS PGD PERFORMED?
Ho o es a e gi e to the o a to si ulate
he o a ies a d e a le the olle io of a u e
of eggs alled oo ytes . Ate the eggs a e
e o ed, the eggs a e fe ilised i the la o ato y
ith spe . Those eggs that a e su essfully
fe ilised di ide a d uliply to fo a de elopi g
e
yo alled a lasto e e. Ate th ee to i e
days, o e o t o ells a e e o ed i o de to test
fo the spe ii ge ei o diio i uesio . The
e o al of these ells does ot appea to ha
the de elopi g e
yo Figure 9. .
O ly those e
yos that do ot ha e the spe ii
ge ei o diio tested fo
ill e t a sfe ed
i to the o a ’s ute us.
ryo is allo ed to gro
.ge ei s.edu.au
for up to i e days so that ells are
Updated
Page of
Septe e
5
Fa t Sheet 29 | PRE-IMPLANTATION GENETIC DIAGNOSIS PGD
Usually, o
o e tha o e e
yo ill e
t a sfe ed to the ute us at a y o e i e to a oid
the possi ility of uliple i ths.
of the IVF p o edu e follo ed y PGD ith that of
te i aio of a afe ted hild o ei ed
atu ally.
I so e IVF u its, u afe ted e
yos that a e
ot used a
e f oze fo t a sfe i a othe
y le.
Fo ouples ith a o al o eligious o je io to
p eg a y te i aio a d ho also ha e a isk
of ha i g a hild ith a ge ei o diio , this
te h i ue ay p o ide the oppo tu ity to ha e
a u afe ted hild.
WHAT ARE THE ADVANTAGES AND
DISADVANTAGES OF PGD?
Su ess ates fo ha i g a hild f o a IVF y le
follo ed y PGD a y f o IVF e t e to e t e
ut te d to follo sta da d IVF su ess ates.
The efo e a p eg a y a d a u afe ted hild
a ot e gua a teed usi g this te h i ue
Like a y IVF p o edu e, st ess a d ote
disappoi t e t a a o pa y PGD. Couples ill
eed to ala e the i a ial a d e oio al ost
I othe s, PGD ay e a p efe ed opio o e
p e atal tesi g i
a
atu ally o ei ed
p eg a y. It a also eli i ate the possi ility of
epeated is a iages fo ouples he e o e
pa t e a ies a h o oso al t a slo aio .
I Aust alia, PGD is u e tly o ly ofe ed i the
p i ate sei g. Ge ei ou selli g is i po ta t
efo e o side i g PGD.
.ge ei s.edu.au
Updated
Page of
Septe e
5