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Mutiara Medika
Edisi Khusus Vol. 8 No. 2: 89 - 95, Oktober 2008

Efikasi Binahong (Anredera cordifolia (Tenore) Steenis) terhadap
Kadar Alkaline Phosphatase
Efficacy Binahong (Anredera Cordifolia (Tenore) Steenis) Leaf
to Alkaline Phosphatase Level
1

Salmah Orbayinah, 2Adhita Kartyanto
1
Bagian Biokimia Fakultas Kedokteran Universitas Muhammadiyah Yogyakarta,
2
Fakultas Kedokteran Universitas Muhammadiyah Yogyakarta

Abstract
Role of Binahong (Anredera cordifolia (Ten.) Steenis) leaves as hepatoprotector and
antioxidant was identified on CCl4 – induced white rats.
Unrandomized control trial method was used in this study. Ten male Wistar white rats
with 200 – 250 gr of body weight were divided into two groups. Group I as a control group
was treated with standard food and 1 ml aquadest orally for 12 days. Group II as a treatment

group was given standar food and daily single dose pretreatment of Binahong (Anredera
cordifolia (Ten.) Steenis) leaves juice 289,8 mg/200 gr of body weight for 12 days. Carbon
tetrachloride (1 ml/kg body weight, i.p.) injected into rats in the day 13th to induce liver cells
damage. ALP test used ALP KIT reagent had been done twice, 1st day and 14th day.
The result shows mean of ALP level before and after treatment in control group were
95,94+1,52 and 110,15+1,07; in treatment group were 92,65+3,05 and 92,91+0,68. Paired
T-test shown significant difference before and after treatment (p