Process Validation of Diclofenac Sodium Patch Membrane Type With Menthol as Enhancer. Repository - UNAIR REPOSITORY

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R T EEE I

THE

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3" INTERNATIONAL CONFERENCE

ON

PHARIIACT [ilD ADVANI]I)
PHARIIAO]UTIOAI, SCI]ilC]S
Book 1:
Pharmaceutical Science & Technology

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Faculty of Pharmacy
Universitas Gadiah Mada
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SCIENCES

Llniverciteit L]trecht

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PROCEEDING
The 3'd lnternational Conference on
Pharmacy And Advanced Pharmaceutical Sciences
June 18 - L9, 2Ot3 Yogyakarta, lndonesia

Book 1:
Pharmaceutical Science & Thecnology

I

Editors:

Abdul Rohman
Zullies lkawati
Tri MurtiAndayani
Riris lstighfari Jenie

Marlyn Dian Laksitorini

Organised By

W

FACULTY OF PHARMACY
UNIVERSITAS GADJAH MADA

Supported By

@..afi.*ffi**

tffiffiEr'
lSsinggENg@$sg

Preface Fr

Published by:
Faculty of Pharmacy Gadjah Mada University
Sekip Utara, Yogyakafta, 55281,
Indonesia

On beha

very hard for l
Pharmacy and

,

Faculty of Pharn

ISBN : 97 A-602-[594-01-8
We wou

their valuable

First Edition, 2013
No part of this publication may be reproduced, stored in a retrieval system or

transmitted

in any form or by any

No responsibility is assumed by the publisher for any injury and/ or damage

persons or property as a matter of product liability, negligence or
othenruise, or from any use or operation of any methods, products,
instructions or ideas contained in the material herein.
Printed in Yogyakarta, Indonesia

r

t

poster pres€nt(
submitting their

means, electronic, mechanical,

photocopying, recording or othemrise, without the prior written permission of
the publisher, Faculty of Pharmacy, Gadjah Mada University, Yogyakarta,
Indonesia,

to

committee for

Finally, r

advance scientif

Yogyakarta, Jurx

Chief

Abdul Rohman

Tbe i,n Intenational Conference

tn Pbamtaq

and Admnced Pbarmaceutical Scimcet

Preface From Editor
On behalf of the Editors, I am deeply grateful to all the reviewers who have been working
very hard for reviewing manuscripts submitted during the "3'd lnternational Conference on
Pharmacy and Advanced Pharmaceutical Sciences" held in Sheraton Hotel Yogyakarta, by the
Faculty of Pharmacy, Gadjah Mada University, Yogyakarta, lndonesia on 18 - 19 June 2013.
We would like to acknowledge to keynote speakers and all the distinguished speakers for

their valuable contribution during this conference. Furthermore, we also thank the steering

lval system or
mechanical,

permission of
, Yogyakarta,

d/ or damage
regligence or

ds,

products/

committee for their advice and support. Finally, I would appreciate to all participants, paper and
poster presenters who participated in the conference as well as cordially contributed by
submitting their full manuscripts published in this proceeding.
Finally, we believe that the presence of this proceeding will significantly contribute to the
advance scientific research, especially in the field of Pharmaceutical Science and Thecnology.

Yogyakarta, June 2013,

Chief

Abdul Rohman

The

jd

Intemational Conference on Phamaq And Atbanced Phatmacettical Sciencet

Welcome to YogYakarta
Assalamu'alaikum wr wb
Honorable Rector of Universitas Gadjah Mada, Prof. Dr. Praktino, M'Soc'
Honorable our keynote speaker : dr. Boeniamin Setiawan, PhD
Honorable our distinguished invited speakers, our guests, and all participants

of all, let us
able to attend this
First

praise to the Almighty Allah SWT, because of His Blessing we are

opening ceremony of the lnternational Conference on Pharmacy and

Remark
Dean, Facult

Firstly, let's thar
wonderful meet

Sciences (l@APl

to welcome Cl

advanced pharmaceutical sciences today.

This morning, it is a great honor for me to welcome you all in this room in our conference'
Welcome to yogyakarta, and we hope you will enjoy your time here. This conference is the third
international conference conducted by Faculty of Pharmacy Universitas Gadjah Mada to
facilitate the experts meeting and sharing the knowldege among the researchers, academia,
college students, policy makers in corresponding fields, and practitioners.
This year, the theme of The 3'd lnternational Conference on Pharmacy and Advanced

pharmaceutical Sciences (ICPAPS 2013) is : "Pharmaceutical development towards a sustainable
and healthy society''. The conference is conducted in collaboration with Utrecht University the
Netherland, Nara lnstitute of Technology Japan, Mahidol University Thailand, and Cyberjaya
University, Malaysia. Thank you very much for our international partners.
Setiawan, PhD'
As a key note speaker in this conference, we are fortunate to have dr. Boenjamin
in
lndonesia. His
pharmaceutical
company
He is the founder of Kalbe Farma, one of the big
his vision in
as
well
as
bussinessman
a
as
company
pharmaceutical
experience in developing
and
inspiring,
be
very
will
lndonesia
in
research
pharmaceutical
and
medical
of
development
hopefully will guide us to develop research in our respective fields. We also invited 12 more
or
experts in various field of pharmacy and pharmaceutical sciences, either from lndonesia
give
their lectures.
overseas, who will
present their
Here, among 300 participants, there are 175 presenters from 10 countries will
recent research finding, which are divide into two big topics, Pharmaceutical Science and
gratitude are
Technology and Clinical and Social Pharmacy. Our high appreciation and sincere
conference.
participate
in
our
presenters
who
enthusiastically
delivered to all speakers and
Nara
The organizing commitee deeply acknowledges The Rector of Universitas Gadjah Mada,
Malaysia'
University,
Cyberjaya
and
Thailand,
lnstitute of Technology Japan, Mahidol University
As the chairman of
as well as the sponsors for nice collaboration in conducting the conference.
gratitude
to allteam
and
appreciation
high
our
to
express
like
personally
would
I
the committee,
of the
members for the hard work, dedication, and invaluable efforts for the success

conference.
enjoyable
Finally, we do hope that all participants could get benefit from this event and have
moment in Yogyakarta.
Wassalamu'alaikum wr wb.
Chairman
Zullies lkawati

ll

c

Yogyakarta{ndo

Secondly, we'd I
erected in Sept€
of Pharmacy in

intemationally i

several Natixral
one of those is I

have been

eq

Therefore, then
towards a grsft
Pharmacy Gl/l'l

specifrcally Phan

Finally, Frutty

<

all

participrrB
lnternationd pa

Thailand, Cyteri
hard, and last b
Faculty of Ph.m
Sincerely,
Subagus

Wahnr

Tbe

ld

Intenatiotal Confennce on PbamaE

and Adaanced Pbamaceutical

Scimnr

Remark
Dean, Faculty of Pharmacy, Gadjah Mada University

i

Blessing we are
on Pharmacy and

in our conference.
ference is the third

Gadjah Mada to
rarchers, academia,

rcy and Advanced
rards a sustainable
'echt University the

rnd, and Cyberjaya
Lmin

Setiawan, PhD.

ry in lndonesia. His
vell as his vision in
very inspiring, and
so invited 12 more
from lndonesia or

Firstly, let's thanks to Allah who always blesses to all of us, so that we can get together in this
wonderful meeting, the 3'd lnternational Conference on Pharmacy and Advanced Pharmaceutical
Sciences (ICPAPS 2013). The Faculty of Pharmacy, Gadjah Mada University (GMU) is very happy
to welcome all of you ICPAPS 2013 participants in the meeting and also we welcome all of you in
Yogyakarta-lndonesia, the home of the Faculty of Pharmacy GMU.
Secondly, we'd like to give a brief introduction of our institution. Faculty of Pharmacy GMU was
erected in September L946, a year after lndonesian lndependence, is noted as the oldest Faculty

of

Pharmacy in lndonesia. Faculty of Pharmacy GMU has been accredited nationally and
internationally as well. ln addition, collaboration in research, education, social services with
several National and overseas lnstitutions have been established, intended to achieve our goals,
one of those is qualityof education. Recently, new regulations on Pharmacist roles in lndonesia
have been emphasized as health profession, health promoter and pharmaceutical care.
Therefore, theme of this ICPAPS 2013 meeting is selected as 'Pharmaceutical developments
towards a sustainable and healthy society' that is parallel to those regulations. Faculty of
Pharmacy GMU really hopes that this meeting is fruitful for all participants in general and
specifically Pharmacy lnstitutions to develop to improve their education system.

s will present their
lutical Science and

Finally, Faculty of Pharmacy GMU highly appreciates to the Keynote speakers, invited speakers,
participants for spending your time with us, the Committee ISteering Committee,
lnternational partners (Universiteit Utrecht-The Netherland, NAIST-Japan, Mahidol UniversityThailand, Cyberjaya University-Malaysia) Organizing Committeel who have been working very
hard, and last but not least Faculty of Pharmacy GMU thanks to our sponsors for this meeting.
Faculty of Pharmacy GMU realizes that without your participation, this meeting never happens.

incere gratitude are
rr conference.

Sincerely,

Gadjah Mada, Nara
Jniversity, Malaysia,
As the chairman of

all

Subagus Wahyuono

3ratitude to all team
lhe success of the

and have enjoyable

ilr

The 3d Inlemational Conlerence on Pbanlacy And Adaanced Pbamacestical Sciences

Table of

Rector Speech

Cr

Preface From Ed

Rector, Universitas Gadjah Mada

It gives me genuine pleasure that Universitas Gadjah Mada has the honor of hosting the
lnternational Conference on Pharmacy and Advanced Pharmaceutical Sciences, which this year is
in its third installment. This Conference, held in collaboration with Japan's Nara lnstitute of
Sciences and Technology, the Netherlands' Universiteit Utrecht, Thailand's Mahidol University
and Malaysia's Cyberjaya University, reflects a global commitment maintained by members of
prominent think tanks the world over in addressing issues of common concern, which in this
year's ICPAPS are Advanced Pharmaceutical Science and Social and Clinical Pharmacy.

Remark

Welcome toYog
Rector Speech
Table of Contenl

FORMUI TIOi{

Universitas Gadjah Mada, as a leading institution of higher learning in lndonesia, and in its
commitment at becoming a World-Class Research University, has long since realized the spinal
role of global cooperation in achieving our visions. This is why we welcome any and all effort
through which international exchanges of thoughts and expertise can be encouraged. I see this
perspective reflected in its entirety in ICPAPS, wherein experts and thinkers from all around the
world will gather together and talk of a concerted effort to enhance the quality of pharmacists
worldwide, broaden the insights on pharmacy as well as pharmaceutical sciences and
technologies, and finally create both a national and international networking system for the
dissemination of developments in pharmaceutical sciences and technologies.

I

OF MAHKOTAO{

A.KorimZulbmt
ANTONDATTA

YULGARE SEED (

Churiyoh, Kunilt
ESTROGENIC EI
OVARIECTOI,CT

Kumio Agtustiri,
ASSESSNG THE

Since those are very noble causes we all need

to not only address, but also eventually produce

into reality, I cannot impress the importance of this Conference for everyone present. Therefore,
I can only hope that all the participants, be they researchers, academicians, pharmacists in and
outside hospitals, as well as the students, are determined in making the best out of this brief
gathering.

SEED DfiRACTS

NorAdilo

l&otn

COMPARATTVE I

nordus L) BETW

RitoTpkrqrorrl

I am looking forward to seeing rigorous debates, heated discussions and, most importantly,

a

result that represents a joint international action held together by scientific truth. Thank you for

MICROWAVE A
AND IT5 ACITVIT

all your commitment and dedication in organizing and contributing to this conference, and I wish
you all the very best of luck.

Juni Ekowti, Ei,

Prof. Dr, Pratikno, M,Soc. Sc.

ARTESUTIATE.

INFLUENCE

Of

Timbul turtocj h
ANTllvlAl-ARIAL

r

FALqPAAUM
Wiwied E,Tutit:
EFFECT

OF

AI{']

ISOLATED FROH

Rohordjo DN,

IV

h

Tbe

id

Intemational Confercnce on Phamag and Adaanced Pltarmacetiical Scimcet

Table of Content
Preface From Editor

)nor
es,

of

hosting the

which this year is

Remark

ii

Welcome to Yogyakarta

iii

Rector Speech

iv

Table of Content

v

fs Nara lnstitute of
Mahidol University
ned by members of
ncern, which in this
ulrmacy.
rdonesia, and

in

its

l realized the spinal
e any and all effort
couraged. I see this
from all around the
ality of pharmacists
rtical sciences and
dng system for the

FORMULATION OF SUNSCREEN CREAM AND LOTION FROM ETHANOLIC EXTRACT
OF MAHKOTA DEWA Phaleria macrocarpa (Scheff) Boerl) LEAVES

1-8

A.Korim Zulkarnoin, Morchobon, Subogus Wohyuono, Rotno Asmoh Susidarti
ANTIOXIDANT AND CYTOTOXIC ACTIVITY OF ETHANOLIC EXTRACT OF FOENICULUM
VULGARE SEED ON PROSTATE CANCER DU-143 CELL
Churiyoh, Kurnio Agustini, Susi Kusumoningrum, Nizor
ESTROGENIC EFFECT

OF LEUNCA FRUIT EKIRACI lSolonum nigrum L.)

9-14

ON Ls-Zt

OVARIECTOMIZED WHITE FEMALE RAT
Ku

rnio Ag

u sti ni, Chu riyo

ASSESSTNG

h,

Fi rdoyo n

i

THE POTENT|AL BtOACTtVtTy OF ?|THECELLOB|UM IR\NGA (JER|NG)

22-25

eventually produce

sEED EXTRACTS ON METHtCtLLtN-RESTSTANT STAqHYLOCOCCUS AUREUS (MRSA).

present. Therefore,
pharmacists in and

Nor Adilo lbrohim, Poziloh lbrohim ond Surioni Mohomod

gst

COMPARATIVE REPELLENCY DURATION OF CITRONELLA OIL LOTTON (Cymbopogon
nordus L.l BETWEEN Culex sp. WITH Aedes.sp AS LYMPHATIC FILARtAStS VECTOR
Rito Tjokropronoto, Rosnoeni, Marshellio Setiowon, Alvin Elioto Cohyono

25-31

MICROWAVE ASSISTED SYNTHESIS OF ETHYL P-METHOXYCI NNAMATE DER IVATIVE
AND ITS ACTIVITY TO BLOCADE COX-2 EXPRESSION ON BREAST CANCER CELL LINE
Juni Ekowoti, Bimo A. Tejo, Imom Susilo, Sukordimon, Siswondono, Tutuk Budioti

32-38

out of this brief

nost importantly,

a

:ruth. Thank you for
rference, and I wish

INFLUENCE

OF MILLING

PROCESS

ON SOLID STATES

TRANSFORMATION OF

39-46

ARTESUNATE.

Timbul Portogi H, Sundoni Noerono Soewandhi, lessie Sofia P., don Soleh Wikorso
ANTIMALARIAL ACTIVITY OF LEAVE OF O45S/A SPECTABILIS AGAINST PIASMODIUM
FALCIPARUM

47-57

Wiwied E, Tutik Sri W, lndah ST
EFFECT

OF ANTIBIOTIC

lN

PEPTIC ULCER THERAPY AGATNST Lactobocillus sp.

ISOLATED FROM FERMENTED MILK PRODUCT: lN VITRO STUDY
Rohardjo DN, PontjojoniT, Kristin A

V

52-55

Tbc 1d latcmatiorul Conlcnna on Pbanaq

sTUDY TNTERACTION

OF

Awl Atlvanccd Phamacctttical Scicnca

ACETAMINOPHEN

AND

O-(3-CHLOROBENZOYL)-

56-59

APPROACH
ACETAMINOPHEN WITH CYCLOOXIGENASE-2 (31N1) BASE ON lN SILICO
T ri Wid io n do n i, I stifodo h, Sisw ond ono

-

CHITOSAN MICROPARTICLE FOR
THEOPHYLLINE
MOD|FIED RELEASE DOSAGE FORM Adityo Trios Pradono, Muh. Agus syomsur Riial,

THE

DEVELOPMENT

OF

60-67
-:-

-

Dewi lsodiortuti
ilicifolius L'
ANTIBACTERIAL AND FREE RADICAL SCAVENGING ACTIVIW OF Aconthus
(ACANTHACEAE) FROM CILACAP IN DONESIA

FOR
THE EMPLOYMENT OF FTIR SPECTROSCOPY COUPLED WITH CHEMOMETRICS
ANALYSIS OF LARD IN CREAM COSMETICS

- _

r. ^ : :__::
!'-

lOcimum canum
ACUTE TOXICITY TEST OF ETHANOL EXTRACT oF
Febrioni
Ayu
Aieng
Nurmeilis,
Sims) ON MALE WHITE MICE Eko Putri,

:_

58-72

Binar Asrining Dhiani, Diniatik Diniatik, Siti Mundiyarti
KEMANGI HERB

l:

: :- - -

73-77

-'

:

:-

;::-:.'-

---,

THE @ST AXAI

78-84

lNTH^llI,lO
Ponmpfutgra

Zilhodia, Nurmeilis

INFLUENCEoFSoDIUMCHLoRIDEcoNcENTRATIoNoNTHEAMoUNToF

85-87

METABOLITE THAT PRODUCED FROM KIMCHI FERMENTATION

Miro Andom Dewi, Nurdionoh Azinor, Morino Wiioyo
ANTIINFLAMMATORY POWER

ENRA
Sri

OF

CHRYSANTHEMUM HERBS METHANOLIC

88-92

T ON MALE WHITE RATS INDUCED BY CARAGENIN

Horyonti, Elisa Rinihopsori, Wieke Febyonti losirso

THE OPTIMIZATION OF AVICEL PH 101 AND MANNITOL lN Nigello
TROCHES BY SIMPLEX LATTICE DESIGN
Endong Dwi Wulonsoi, Endong Diyah lkosari, Sisko Prima

sotivo

L- EXTRACT

ACTIVITY
MACRONUTRIENT ANALYSIS, GLYCEMIC INDEX AND ANTI'CHOLESTEROL
OF ARROWRO Of (Mo ro ntoo ru ndi no ce ol.)

Fodliloturrahmah, Rumiyoti, tka Puspito

Sori, Endong

-97

93

98

-

103

Lio

lvt,rlirfr.lo

Lukitoningsih

TYPE WITH
PROCESS VALIDATION OF DICLOFENAC SODIUM PATCH MEMBRANE
MENTHOL AS ENHANCER

104

-

109

tLo

-

Lt7

Dewi Rashoti, Esti Hendrodi, Yuwono

tocAt"tYs(xn(
OF THE ETHANOLIC EXTRACT OF

FORMULATION AND EFFECTS OF THE ADDITION
MANGOSTEEN RIND TOWARDS THE CHEMICAL PROPERTIES OF THE TRANSPARENT

QuodriW-G,Ct
OPTIMEANO'
MUtTrRESrlXf

SOLID BATH SOAP
NPCS.

TOXOTY TEST I
AND FRACIXtrd

Bhuono, NPAD. Wiioyonti, IGNAD. Putro

Setyo

RNA
ACT|V|TY OF MANGOSTEEN lGorcinio mongostono L.) PERICARP EXTRACT AS
HELICASE INHIBITOR OF HEPATITIS C VIRUS

ttg -

,

Pritolilia

723
PREUMINARY

HYD,RAZIDE DCN

Lino Elfito, A. Zaenol Mustopo, Putri Syoiorwot

Noveen Kurrml

FORMULATION PROCESS VALIDATION OF DICLOFENAC SODIUM TRANSDERMAL
PATCH MATRIX TYPE

Cynthia Marisco Muntu, Esti Hendradi, Riesto Primohorinostiti
Vi

124

-

129

lbmhim,

turirir

Tbe

FOR

ANTIOXIDANT ACTIVIIY AND TOTAL FLAVONOID CONTENT IN SOME
BITTER MELON (Momordicacharantia L.) FRUIT EXTRACIS
loko Tri Wibowo, Supormi, Evo Rotno Sari

50-67

IN VIVO IMMUNOMODULATORY EFFECT OF TWO COMPOUNDS ISOLATED FROM
RED BETEL (ptpER CROCATUM RUIZ & pAV.l ON BABVC M|CE TNFECTED W|TH
LISTERIA MONOCYTOGEN

130

-

134

135

-

141

ES

68-72

oonum

73-77

FOR

78-84

OF

85-87

wouc

ETHANOLIC

Yustina Sri Hartini, Subogus Wohyuono, Sitorino Widyorini, Ag. Yuswonto

L.

HT

Conlennce on Phannacy aalAduanced Pltannaceutical Sciences

56-59

Riltl,

cs

Jil Inlematiotal

ANTIOXIDANT CAPACITY OF STEM BARK EXTRACT OF ANTIDESMA NEUROCARPUM
MIQ (EUPHORBIACEAE FAMILY) USING 2,2'-DIPHENYL-I-PICRYLHYDRAZYL (DPPH)
RADICAL SCAVENGING METHOD
Rosmoleno, Suryo Dwiro, Zokioh lJlfoh, Berno Elyo, Tioh Rochmotioh

742- 148

THE COST ANALYSIS OF HEPATOCELLUI.AR CARCINOMA SURVEILIXNCE PROGRAM
IN THAILAND
Ponnopa Songmola, Uso Choikledkoew, Towesok Tonwondee

149

-

153

154

-

159

160

-

164

VITAMIN D: BEYOND THE BONE
Annette d'Arqom, M.D.

165

-

170

TOXTCTTY TEST OF SOURSOP LEAVES (AN/VONA MURTCATA L.) ETHANOL EXTRACT

L7t

-

t74

175

-

180

181

-

187

188

-

194

195

-

203

SYNTHESIS

OF

2,5-Bts-(4-NITROBENZyLtDENE)CyCLOpENTANONE

vtA cLAtSEN

SCHMIDT CON DENSATION REACTION
Fronsisko Ayuningtyos Widyastoni, Moywon Horiono

THE INFLUENCE OF GINGER VARIETIES, COMPARISONS OF
88

-

92

HERBS.SOLVENT
MATERIALS AND TECHNIQUE OF DRYING HERBS TO THE QUANTITY OF SEDIMENTS
FROM GINGER RHIZOME ESSENTIAL OILS (Zingiberis Officinole)

Septiono Lokmi Ramayoni, Sri Widyostuti ond Eufrosio Astrid

XTRACT 93-97

fivrTY

WITH

98

-

103

@9

AND FRACTTONS USTNG BSLT (BR|NE SHRtMp LETHALTW TEST) METHODE
Lio Morlioni , Yoppi lskondor, lon Fiter lrowon
SELF.NANOEMULSIFYING DRUG DELIVERY SYSTEM PREPARATION FOR CURCUMIN
ANALOGUES GAMAVUTON-O AN D PENTAGAMAVUNON-O

Erno Wulondori, Nurul Rohmo Fitriani, Hildo lsmoil, Ronny Martien
LOCALLY SOURCED MAIZE HUSK CELLULOSE AS COMPRESSED TABLET EXCIPIENT

ACT OF

7LO

)ARENT

-

Lt1

Quodri W. G., Bokre Loteel G ond Bamiro O.A
OPTIMIZATION OF HEADSPACE-GAS CHROMATOGRAPHY CONDITION FOR THE

AS

RNA

MULTIRESIDUE ANALYSIS OF ORGANOPHOSPHATE PESTICIDES IN VEGETABLES
Setyo P rihoti ni ngtyo s, Riesto P rimo ha ri no stiti

1L8-T23
PRELIMINARY

/N

Y/IRO ANTI.CANCER ACTIVITIES ON ISONICOTINIC

ACID

HYDRAZIDE DERIVATIVES

Noveen Kumor H.S, Thoigorojan Porumosivom, Mohd.Zoini Asmawi, paziloh

)ERMAL

124

-

129

Ib

rohim, Ami rin Sodikun

vil

Tbe

id

Intematictnal Confennn on Pharrary

DRUG-POLYMER INTERACTION

FORMUL
ETHANOLI,

And Adunced PlLamtacetttical Sciences

AND

BIOACTIVITY

OF

IBUPROFEN-LOADED

204

-

270

ALGINATE MICROSPHERES

Dewi M. Horiyodi, Mork S. Turner, Bhesh Bhondori, Allon G.A. Coombes
KETOPROFEN.CARBOXYMETHYL

CHITOSAN MICROPARTICLES PREPARED BY SPRAY

A.Karim Zull
21'L

-

215

ABSTRACT
Phaleria

DRYING : OPTIMIZATION AND EVALUATION

Retno Sori, Melotino Mogdo, Wini Lestori, M. Agus Syamsur Riial

-

FORMULATION AND EVALUATION OF PREPARATION LIPBALM CONTAINING
BANANA LEATHER OIL (Musa paradisiacal oil)
Titta H Sutorno, Hestiary Rotih, Elso Nurfitriani

216

SYNTHESIS RADIOIMMUNOCONJUGATE OF 1771u-DOTA-F(ab')2-TRASTUZUMAB
FOR RADIOIMMUNOTHERAPY OF BREAST CANCER
Sondro Hermonto, Ratno Dini Horyuni, Mortoleno Romli, Abdul Mutolib, ond Sumi

221-230

220

The purt

Hudiyono
FORMULATION AND EVALUATION OF TRANSDERMAL PATCH OF IBUPROFEN

phalerin and ha!
used as active
phalerin to servr
harmful subtan
Most of facial lir
both UV-A and
melanoma.

23L-

235

creams from Phi
This research m
the leaves with
skin.

Hestiory Ratih, Fikri Alatas, Sinto Rondini
A MONOHYDROXYCHALCONE
Melonny tko Sulistyowaty, Kholis Amalio Nofionti, Suzono, Wiwied Ekosori, Tutuk
SYNTHESIS AND ANTIPLASMODIUM ACTIVITY OF

236

-239

Budioti
A SIMPLE SYNTHESIS OF ISATIN DERIVATIVES WITH 3.HYDROXY-3.(lH.PYRROLE-2YL)tN DOLTN E-2-ONE CORE

Budi Proyitno, Mardi Sontoso

240-248

The resr
frorn ethanolic e
prevent skin en
extract of Phah
of ethanolic o