PENGARUH VITAMIN E TERHADAP KADAR SGOT DAN SGPT PADA TIKUS YANG DIBERI PARASETAMOL - Diponegoro University | Institutional Repository (UNDIP-IR)

LAMPIRAN
1. Foto kandang tikus

2. Sonde oro esofageal untuk memasukkan vitamin E dan PCT

3. Anastesi sebelum pengambilan darah

4. Analisis statistik
Tests of Normality
a
Kolmogorov-Smirnov
Statistic
Df
Sig.
Statistic
sgotpre
.184
26
.023
.885
sgot24

.291
26
.000
.640
sgot48
.284
26
.000
.734
*
sgptpre
.129
26
.200
.934
sgpt24
.329
26
.000
.571

sgpt48
.324
26
.000
.693
a. Lilliefors Significance Correction
*. This is a lower bound of the true significance.

Shapiro-Wilk
df
26
26
26
26
26
26

Sig.
.007
.000

.000
.099
.000
.000

T-Test
Paired Samples Statistics
Mean
Pair 1

N

Std. Deviation

Std. Error Mean

sgotpre

158.0231


26

46.77919

9.17415

sgot24

7368.8269

26

12035.97183

2360.44828

Paired Samples Correlations
N
Pair 1


Pair 1 sgo
tpre
sgo
t24

sgotpre & sgot24

Mean
-7210.80385

Correlation
26

Sig.

-.310

.124

Paired Samples Test

Paired Differences
95% Confidence Interval of
the Difference
Std.
Std. Error
Deviation
Mean
Lower
Upper
12050.54312
2363.30594 -12078.12355
-2343.48414

t
-3.051

Sig. (2tailed)
.005

ANOVA

Sgotpre
Sum of Squares
48381.554
6325.752
54707.306

Between Groups
Within Groups
Total

df
4
21
25

Mean Square
12095.388
301.226

F

40.154

Sig.
.000

Post Hoc Tests
Multiple Comparisons
Dependent Variable:sgotpre

Tukey HSD

(I) grup
1.00

2.00

3.00

4.00


5.00

LSD

1.00

(J) grup
2.00
3.00
4.00
5.00
1.00
3.00
4.00
5.00
1.00
2.00
4.00
5.00
1.00

2.00
3.00
5.00
1.00
2.00
3.00
4.00
2.00
3.00
4.00

Mean
Difference (I-J)
*
-69.65833
3.10833
-11.74167
*
-112.97500
*

69.65833
*
72.76667
*
57.91667
*
-43.31667
-3.10833
*
-72.76667
-14.85000
*
-116.08333
11.74167
*
-57.91667
14.85000
*
-101.23333
*
112.97500
*
43.31667
*
116.08333
*
101.23333
*
-69.65833
3.10833
-11.74167

Std. Error
11.20317
11.20317
11.20317
12.27246
11.20317
10.02042
10.02042
11.20317
11.20317
10.02042
10.02042
11.20317
11.20317
10.02042
10.02042
11.20317
12.27246
11.20317
11.20317
11.20317
11.20317
11.20317
11.20317

Sig.
.000
.999
.830
.000
.000
.000
.000
.007
.999
.000
.585
.000
.830
.000
.585
.000
.000
.007
.000
.000
.000
.784
.307

95% Confidence Interval
Lower Bound
Upper Bound
-103.0330
-36.2837
-30.2663
36.4830
-45.1163
21.6330
-149.5351
-76.4149
36.2837
103.0330
42.9155
102.6179
28.0655
87.7679
-76.6913
-9.9420
-36.4830
30.2663
-102.6179
-42.9155
-44.7012
15.0012
-149.4580
-82.7087
-21.6330
45.1163
-87.7679
-28.0655
-15.0012
44.7012
-134.6080
-67.8587
76.4149
149.5351
9.9420
76.6913
82.7087
149.4580
67.8587
134.6080
-92.9566
-46.3601
-20.1899
26.4066
-35.0399
11.5566

*

5.00
-112.97500
*
2.00
1.00
69.65833
*
3.00
72.76667
*
4.00
57.91667
*
5.00
-43.31667
3.00
1.00
-3.10833
*
2.00
-72.76667
4.00
-14.85000
*
5.00
-116.08333
4.00
1.00
11.74167
*
2.00
-57.91667
3.00
14.85000
*
5.00
-101.23333
*
5.00
1.00
112.97500
*
2.00
43.31667
*
3.00
116.08333
*
4.00
101.23333
*
Bonferroni
1.00
2.00
-69.65833
3.00
3.10833
4.00
-11.74167
*
5.00
-112.97500
*
2.00
1.00
69.65833
*
3.00
72.76667
*
4.00
57.91667
*
5.00
-43.31667
3.00
1.00
-3.10833
*
2.00
-72.76667
4.00
-14.85000
*
5.00
-116.08333
4.00
1.00
11.74167
*
2.00
-57.91667
3.00
14.85000
*
5.00
-101.23333
*
5.00
1.00
112.97500
*
2.00
43.31667
*
3.00
116.08333
*
4.00
101.23333
*. The mean difference is significant at the 0.05 level.

12.27246
11.20317
10.02042
10.02042
11.20317
11.20317
10.02042
10.02042
11.20317
11.20317
10.02042
10.02042
11.20317
12.27246
11.20317
11.20317
11.20317
11.20317
11.20317
11.20317
12.27246
11.20317
10.02042
10.02042
11.20317
11.20317
10.02042
10.02042
11.20317
11.20317
10.02042
10.02042
11.20317
12.27246
11.20317
11.20317
11.20317

.000
.000
.000
.000
.001
.784
.000
.153
.000
.307
.000
.153
.000
.000
.001
.000
.000
.000
1.000
1.000
.000
.000
.000
.000
.009
1.000
.000
1.000
.000
1.000
.000
1.000
.000
.000
.009
.000
.000

-138.4970
46.3601
51.9281
37.0781
-66.6149
-26.4066
-93.6053
-35.6886
-139.3816
-11.5566
-78.7553
-5.9886
-124.5316
87.4530
20.0184
92.7851
77.9351
-104.7826
-32.0159
-46.8659
-151.4517
34.5341
41.3506
26.5006
-78.4409
-38.2326
-104.1827
-46.2661
-151.2076
-23.3826
-89.3327
-16.5661
-136.3576
74.4983
8.1924
80.9591
66.1091

-87.4530
92.9566
93.6053
78.7553
-20.0184
20.1899
-51.9281
5.9886
-92.7851
35.0399
-37.0781
35.6886
-77.9351
138.4970
66.6149
139.3816
124.5316
-34.5341
38.2326
23.3826
-74.4983
104.7826
104.1827
89.3327
-8.1924
32.0159
-41.3506
16.5661
-80.9591
46.8659
-26.5006
46.2661
-66.1091
151.4517
78.4409
151.2076
136.3576

Oneway
ANOVA
sgot24
Sum of Squares
9.477E8
2.674E9
3.622E9

Between Groups
Within Groups
Total

df
4
21
25

Mean Square
2.369E8
1.273E8

F

Sig.
1.861

.155

Post Hoc Tests
Multiple Comparisons
Dependent Variable:sgot24

Tukey HSD

(I) grup
1.00

(J) grup
2.00
3.00

Mean
Difference (I-J)
10630.95833
8271.49167

Std. Error
7283.77769
7283.77769

Sig.
.598
.786

95% Confidence Interval
Lower Bound
Upper Bound
-11067.6879
32329.6045
-13427.1545
29970.1379

2.00

3.00

4.00

5.00

LSD

1.00

2.00

3.00

4.00

5.00

Bonferroni

1.00

2.00

3.00

4.00

5.00

4.00
5.00
1.00
3.00
4.00
5.00
1.00
2.00
4.00
5.00
1.00
2.00
3.00
5.00
1.00
2.00
3.00
4.00
2.00
3.00
4.00
5.00
1.00
3.00
4.00
5.00
1.00
2.00
4.00
5.00
1.00
2.00
3.00
5.00
1.00
2.00
3.00
4.00
2.00
3.00
4.00
5.00
1.00
3.00
4.00
5.00
1.00
2.00
4.00
5.00
1.00
2.00
3.00
5.00
1.00

-4988.50833
6598.07500
-10630.95833
-2359.46667
-15619.46667
-4032.88333
-8271.49167
2359.46667
-13260.00000
-1673.41667
4988.50833
15619.46667
13260.00000
11586.58333
-6598.07500
4032.88333
1673.41667
-11586.58333
10630.95833
8271.49167
-4988.50833
6598.07500
-10630.95833
-2359.46667
*
-15619.46667
-4032.88333
-8271.49167
2359.46667
-13260.00000
-1673.41667
4988.50833
*
15619.46667
13260.00000
11586.58333
-6598.07500
4032.88333
1673.41667
-11586.58333
10630.95833
8271.49167
-4988.50833
6598.07500
-10630.95833
-2359.46667
-15619.46667
-4032.88333
-8271.49167
2359.46667
-13260.00000
-1673.41667
4988.50833
15619.46667
13260.00000
11586.58333
-6598.07500

7283.77769
7978.97869
7283.77769
6514.80882
6514.80882
7283.77769
7283.77769
6514.80882
6514.80882
7283.77769
7283.77769
6514.80882
6514.80882
7283.77769
7978.97869
7283.77769
7283.77769
7283.77769
7283.77769
7283.77769
7283.77769
7978.97869
7283.77769
6514.80882
6514.80882
7283.77769
7283.77769
6514.80882
6514.80882
7283.77769
7283.77769
6514.80882
6514.80882
7283.77769
7978.97869
7283.77769
7283.77769
7283.77769
7283.77769
7283.77769
7283.77769
7978.97869
7283.77769
6514.80882
6514.80882
7283.77769
7283.77769
6514.80882
6514.80882
7283.77769
7283.77769
6514.80882
6514.80882
7283.77769
7978.97869

.958
.919
.598
.996
.155
.980
.786
.996
.284
.999
.958
.155
.284
.519
.919
.980
.999
.519
.159
.269
.501
.418
.159
.721
.026
.586
.269
.721
.055
.821
.501
.026
.055
.127
.418
.586
.821
.127
1.000
1.000
1.000
1.000
1.000
1.000
.259
1.000
1.000
1.000
.546
1.000
1.000
.259
.546
1.000
1.000

-26687.1545
-17171.6010
-32329.6045
-21767.3258
-35027.3258
-25731.5295
-29970.1379
-17048.3925
-32667.8592
-23372.0629
-16710.1379
-3788.3925
-6147.8592
-10112.0629
-30367.7510
-17665.7629
-20025.2295
-33285.2295
-4516.4866
-6875.9533
-20135.9533
-9995.1195
-25778.4033
-15907.7533
-29167.7533
-19180.3283
-23418.9366
-11188.8199
-26808.2866
-16820.8616
-10158.9366
2071.1801
-288.2866
-3560.8616
-23191.2695
-11114.5616
-13474.0283
-26734.0283
-12205.1870
-14564.6536
-27824.6536
-18417.6688
-33467.1036
-22784.7360
-36044.7360
-26869.0286
-31107.6370
-18065.8026
-33685.2693
-24509.5620
-17847.6370
-4805.8026
-7165.2693
-11249.5620
-31613.8188

16710.1379
30367.7510
11067.6879
17048.3925
3788.3925
17665.7629
13427.1545
21767.3258
6147.8592
20025.2295
26687.1545
35027.3258
32667.8592
33285.2295
17171.6010
25731.5295
23372.0629
10112.0629
25778.4033
23418.9366
10158.9366
23191.2695
4516.4866
11188.8199
-2071.1801
11114.5616
6875.9533
15907.7533
288.2866
13474.0283
20135.9533
29167.7533
26808.2866
26734.0283
9995.1195
19180.3283
16820.8616
3560.8616
33467.1036
31107.6370
17847.6370
31613.8188
12205.1870
18065.8026
4805.8026
18803.2620
14564.6536
22784.7360
7165.2693
21162.7286
27824.6536
36044.7360
33685.2693
34422.7286
18417.6688

2.00
4032.88333
3.00
1673.41667
4.00
-11586.58333
*. The mean difference is significant at the 0.05 level.

7283.77769
7283.77769
7283.77769

1.000
1.000
1.000

-18803.2620
-21162.7286
-34422.7286

26869.0286
24509.5620
11249.5620

ANOVA
delta24pre
Between Groups
Within Groups
Total

Sum of Squares
9.538E8
2.677E9
3.630E9

df
4
21
25

Mean Square
2.385E8
1.275E8

F

Mean Square
2837473.082
2292170.222

F

Mean Square
75.435
57.402

F

Sig.
1.871

.153

Oneway
ANOVA
sgot48
Between Groups
Within Groups
Total

Sum of Squares
11349892.327
48135574.657
59485466.983

df
4
21
25

Sig.
1.238

.325

Oneway
ANOVA SGPT PRE
ANOVA
sgptpre
Between Groups
Within Groups
Total

Sum of Squares
301.739
1205.444
1507.183

df
4
21
25

Sig.
1.314

.297

T-Test

Pair 1

Pair 1

sgotpre
sgot24

Paired Samples Statistics
Mean
N
Std. Deviation
122.5750
4
12.40763
11594.8250
4
19599.63113

Paired Samples Correlations
N
Correlation
sgotpre & sgot24
4
-.455

Pair 1 sgotpre sgot24

Mean
-11472.25000

Std. Error Mean
6.20381
9799.81557

Sig.
.545

Paired Samples Test
Paired Differences
95% Confidence Interval
of the Difference
Std.
Std. Error
Deviation
Mean
Lower
Upper
19605.28538 9802.64269 -42668.63401 19724.13
401

t
-1.170

df
3

Sig. (2tailed)
.326

NPar Tests
SGOT PRE DAN 24 JAM P0

Wilcoxon Signed Ranks Test
Ranks
Mean Rank

N
sgot24 - sgotpre

Sum of Ranks

a

Negative Ranks

0

Positive Ranks

4

Ties

0

.00

.00

2.50

10.00

b

c

Total

4

a. sgot24 < sgotpre
b. sgot24 > sgotpre
c. sgot24 = sgotpre
b

Test Statistics

sgot24 - sgotpre
a
-1.826
.068

Z
Asymp. Sig. (2-tailed)
a. Based on negative ranks.
b. Wilcoxon Signed Ranks Test

SGOT PRE DAN 24 P1

Wilcoxon Signed Ranks Test
Ranks
N
sgot24 - sgotpre

a

Negative Ranks
Positive Ranks
Ties
Total

0
b
6
c
0
6

Mean Rank
.00
3.50

Sum of Ranks

Mean Rank
1.00

Sum of Ranks
1.00

.00
21.00

a. sgot24 < sgotpre
b. sgot24 > sgotpre
c. sgot24 = sgotpre
b

Test Statistics
Z
Asymp. Sig. (2-tailed)
a. Based on negative ranks.
b. Wilcoxon Signed Ranks Test

sgot24 - sgotpre
a
-2.201
.028

SGOT PRE DAN 24 P2

Wilcoxon Signed Ranks Test
Ranks
N
sgot24 - sgotpre

Negative Ranks

a

1

b

Positive Ranks
Ties
Total

5
c
0
6

4.00

20.00

a. sgot24 < sgotpre
b. sgot24 > sgotpre
c. sgot24 = sgotpre
b

Test Statistics

sgot24 - sgotpre
a
-1.992
.046

Z
Asymp. Sig. (2-tailed)
a. Based on negative ranks.
b. Wilcoxon Signed Ranks Test

SGOT PRE DAN 24 P3

Wilcoxon Signed Ranks Test
Ranks
N
sgot24 - sgotpre

a

Negative Ranks
Positive Ranks
Ties
Total

0
b
6
c
0
6

Mean Rank
.00
3.50

Sum of Ranks

Mean Rank
.00
2.50

Sum of Ranks

.00
21.00

a. sgot24 < sgotpre
b. sgot24 > sgotpre
c. sgot24 = sgotpre
b

Test Statistics

sgot24 - sgotpre
a
-2.201
.028

Z
Asymp. Sig. (2-tailed)
a. Based on negative ranks.
b. Wilcoxon Signed Ranks Test

SGOT PRE DAN 24 P4
Wilcoxon Signed Ranks Test
Ranks
N
sgot24 - sgotpre

Negative Ranks
Positive Ranks
Ties
Total

a. sgot24 < sgotpre
b. sgot24 > sgotpre
c. sgot24 = sgotpre
b

Test Statistics
Z
Asymp. Sig. (2-tailed)
a. Based on negative ranks.
b. Wilcoxon Signed Ranks Test

sgpt24

sgot24 - sgotpre
a
-1.826
.068

a

0
b
4
c
0
4

.00
10.00

Sum of Squares
3.585E8
6.222E8
9.807E8

Between Groups
Within Groups
Total

df
4
21
25

Mean Square
89631824.312
29628309.099

F

Sig.
3.025

Post Hoc Tests
Multiple Comparisons
Dependent Variable:sgpt24

Tukey HSD

(I) grup
1.00

2.00

3.00

1.00
2.00
4.00
5.00

4.00

1.00
2.00
3.00
5.00
1.00
2.00
3.00
4.00
2.00
3.00
4.00
5.00
1.00
3.00
4.00
5.00

5.00

LSD

1.00

2.00

3.00

1.00
2.00
4.00
5.00

4.00

1.00
2.00
3.00
5.00
1.00
2.00
3.00
4.00
2.00
3.00

5.00

Bonferroni

(J) grup
2.00
3.00
4.00
5.00
1.00
3.00
4.00
5.00

1.00

Mean
Difference (IJ)
5082.26667
5120.00000
4330.16667
-5121.47500
-5082.26667
37.73333
-752.10000
10203.74167
-5120.00000
-37.73333
-789.83333
10241.47500
-4330.16667
752.10000
789.83333
-9451.64167
5121.47500
10203.74167
10241.47500
9451.64167
5082.26667
5120.00000
4330.16667
-5121.47500
-5082.26667
37.73333
-752.10000
*
10203.74167
-5120.00000
-37.73333
-789.83333
*
10241.47500
-4330.16667
752.10000
789.83333
*
-9451.64167
5121.47500
*
10203.74167
*
10241.47500
*
9451.64167
5082.26667
5120.00000

95% Confidence Interval
Std. Error
3513.56355
3513.56355
3513.56355
3848.91602
3513.56355
3142.62677
3142.62677
3513.56355

Sig.
.606
.600
.733
.676
.606
1.000
.999
.058

Lower Bound
-5384.7706
-5347.0372
-6136.8706
-16587.5398
-15549.3039
-9324.2694
-10114.1027
-20670.7789

Upper Bound
15549.3039
15587.0372
14797.2039
6344.5898
5384.7706
9399.7360
8609.9027
263.2956

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