The Relationship consumption of alcohol with chronic kidney failure.

12 Clinically patients aged ≥60 years had a risk 2.2 times greater than suffering from chronic kidney failure patients aged 60 years Pranandari Supadmi, 2014. Chronic kidney failure is influenced by age occurs naturally or is called the aging process in which all organs function decline. In the process also decreased kidney function by slowing the process of filtration and excretion of glomerular and tubular worsening. The function decline is a normal process but due to the presence of risk factors or other external causes abnormalities in the kidneys and renal function decline rapidly or progressively, causing complaints and symptoms were abnormal in kidney condition is called chronic renal failure. 3.1.2 The relationship of hypertension with chronic kidney failure Bivariate statistical test results above showed that there is significant relationship between the incidence of hypertension and chronic renal failure p = 0.001. Statistical test results show that respondents who have a history of hypertension more at risk of suffering chronic renal failure than those not suffering from hypertension. Retrieved OR 55.59 which means that respondents who have a history of hypertension 55.59 times likely to suffer from chronic kidney failure than those without a history of hypertension. The results of this study are also consistent with several previous studies Tjekyan 2014 states that there is a significant relationship between hypertension with chronic renal failure p=0.001. In clinic patients with a history of hypertension at risk of suffering from chronic renal failure is greater 4.04 compared with patients who did not have a history of hypertension. Nurjanah, 2012 in his research she state that the longer respondents have hypertension then the chances of risk of suffering from chronic kidney failure is increasing. Hypertension is a risk factor for chronic kidney disease. Increased blood pressure can aggravate the kidneys and made more severe damage to the kidneys caused intraglomeruler increasing pressure, causing disturbances in glomerular function. The conditions that make hypertension as a risk factor for chronic renal failure. 3.3.3 the relationship between the incidence of diabetes mellitus with chronic failed kidney The results of the bivariate analysis showed there is relationship between the incidence of diabetes mellitus with chronic renal failure p=0.001. The results of this analysis showed respondents with diabetes mellitus is more risk of suffering from chronic renal failure compared to those without diabetes mellitus. Retrieved OR=3.29, which means that respondents who had a history of diabetes mellitus 3.29 times the chance of suffering from chronic kidney failure than those without a history of diabetes mellitus. The results of this study supported previous research conducted by Dewayani 2007 suggested a link between diabetes mellitus who significant kidney failure conical. Respondents who have a history of diabetes mellitus are at risk was 5.39 times greater than the subject the study who had no history of diabetes mellitus. Afolabi 2009 stated that the subject of a study with diabetes mellitus decreased higher GFR 60ml min 173m2 than respondents without diabetes mellitus. Chronic renal failure patients with diabetes mellitus ESRD more than renal chronic failure patients without diabetes mellitus. The physical condition with high blood sugar can lead to fibrosis and inflammation in the kidney tubules. This condition causes a decline and progressive renal damage Nicholas, 2013

3.3.4 The Relationship consumption of alcohol with chronic kidney failure.

Bivariate statistical test results above showed that there is significant relationship between alcohol consumption with the incidence of chronic renal failure p = 0.003. Results of the analysis showed 13 that the more the amount of consumption of alcoholic drinks per day, the risk of suffering from chronic renal failure will be higher than those who did not. Retrieved OR 7.45, which means that the respondents in the last 2 years had a history of consuming alcoholic beverage s ≥3x week by 7.45 times likely to suffer from chronic kidney failure compared to respondents who consume alcohol 3x week. Results of other studies that support this research conducted by Lipworth et al., 2012 states that consuming alcohol continuously improve the level of creatinine. Excessive alcohol drinkers have higher creatinine levels than those not consuming alcohol. So we can conclude respondents who consumed alcohol continuously tend risk of suffering from chronic renal failure compared to respondents who did not consume alcohol. 3.3.5 The Relationship consumption of Energy Drink with chronic kidney failure Bivariate statistical test results showed that there is a significant relationship between beverage consumption energy drink with the incidence of chronic renal failure p = 0.001. Results of the analysis showed that the more the amount of consumption of energy drinks per day, the risk of suffering from chronic renal failure will be higher than those who did not. Retrieved OR 11.49, which means that the respondents in the last 2 years who had a history of consuming energy drinks ≥3x week 11.49 times likely to suffer from chronic kidney failure compared to respondents who consumed energy drinks 3x week. Results of other studies that support this research conducted by Puspitasari and Kusnadi 2012 states that there is a significant relationship between the consumption of energy drinks with chronic kidney failure. Respondents who consumed energy drinks containing caffeine 1 bottle or 1 pack of sports drink supplement 2 times more risk of suffering from chronic renal failure compared to respondents who did not consume Hidayati, Kushadiwijaya Suhardi, 2008. Some of the substances contained in energy drinks or drink supplements such as caffeine, amphetamines and taurine can affect the working system and kidney function. These substances cause blood vessels to the kidney arteries narrowed so that the blood to the kidneys is reduced. This condition causes the kidneys deprived of oxygen and nutrition to the cells of the kidney were deprived of oxygen and will get ischemia and trigger inflammation that can cause damage to the kidney, so the kidneys ability to filter blood decreases Strippoli, 2011.

3.3.6 The Relationship consumption of NSAID with chronic kidney failure.