Gambaran Penyakit Kanker Ovarium Di Rumah Sakit Hasan Sadikin Bandung Periode Januari 2011 - Desember 2011.

ABSTRAK
GAMBARAN PENYAKIT KANKER OVARIUM DI RUMAH SAKIT
HASAN SADIKIN BANDUNG PERIODE JANUARI 2011-DESEMBER
2011
Adindha, 2012; Pembimbing I : Laella K. Liana, dr., Sp. PA., M. Kes.
Pembimbing II : Rimonta F. Gunanegara, dr., Sp.OG.
American Cancer Society (ACS) memperkirakan akan terdapat 22.880 kasus
baru kanker ovarium pada tahun 2012 dan 15.500 diperkirakan meninggal.
Kanker ovarium termasuk lima penyebab utama kematian pada wanita. Biasanya
mengenai wanita usia 40-65 tahun dan jarang pada usia dibawah 40 tahun.
Kelainan ini jarang memberi gejala pada stadium awal dan sering kali ditemukan
pada stadium lanjut sehingga diagnosis dini sangatlah penting.
Tujuan penelitian ini adalah untuk mengetahui gambaran pasien kanker
ovarium dengan karakteristik distribusi menurut golongan usia, jumlah paritas,
keluhan utama, jenis kanker ovarium, stadium dan terapi yang dilakukan di
Rumah Sakit Hasan Sadikin Bandung periode Januari 2011-Desember 2011.
Metode penelitian dilakukan secara survey deskriptif dengan rancangan
penelitian retrospektif terhadap data rekam medik pasien rawat inap penderita
kanker ovarium di Rumah Sakit Hasan Sadikin Bandung periode Januari 2011Desember 2011.
Hasil yang diperoleh menunjukkan pada periode Januari 2011-Desember 2011
terdapat 72 kasus kanker ovarium. Kelompok usia terbanyak terdapat pada

rentang usia 41-50 tahun (38,9%), dengan paritas 0 (22,2%), dan keluhan utama
terbanyak berupa benjolan di perut (86,1%). Jenis terbanyak didapatkan
kistadenokarsinoma musinosum (48,6%) dan 40,3% penderita ditemukan pada
stadium IIIC. Empat puluh empat koma empat persen penderita dilakukan terapi
surgical staging.
Kata Kunci: kanker ovarium, gambaran, Rumah Sakit Hasan Sadikin

vi

ABSTRACT

THE OVERVIEW OF OVARIAN CANCER AT HASAN SADIKIN
HOSPITAL BANDUNG PERIOD JANUARY 2011–DESEMBER 2011
Adindha, 2012; Tutor I : Laella K. Liana, dr.,Sp.PA., M. Kes.
Tutor II : Rimonta F. Gunanegara, dr., Sp.OG.
American Cancer Society (ACS) estimates that there will be 22.880 new cases
of ovarian cancer in 2012 and 15.500 predicted to die. Ovarian cancer includes
five major causes of death in women, usually women aged 40-65 years and rare
below 40 years old. The disorder is rarely gives symptoms in its early stages and
often found at an advanced stage, so early diagnosis is important.

The purpose of this study was to determine the image characteristics of
ovarian cancer patients according to age group distribution, the number of parity,
major complaint, type of ovarian cancer, stage and treatment performed in Hasan
Sadikin Hospital Bandung period January 2011-December 2011.
The research method is a descriptive survey with retrospective design of the
medical record of inpatients with ovarian cancer at Hasan Sadikin Hospital
Bandung, for period January 2011-Desember 2011.
The results obtained from the period January 2011-December 2011 were 72
cases of ovarian cancer. Most age groups are in the age range 41-50 years
(38.9%), with parity 0 (22.2%), and most of the major complaints is a lump in the
abdomen (86.1%). The most frequent histopathological type is mucinous
cystadenocarcinoma (48.6%) and 40.3% of patients found in stage IIIC. Fourtyfour point four percent of patients were treated with surgical therapy staging.
Keyword : ovarian cancer, overview, Hasan Sadikin Hospital

vii

DAFTAR ISI
JUDUL............................................................................................................
LEMBAR PERSETUJUAN...........................................................................
SURAT PERNYATAAN...............................................................................

KATA PENGANTAR....................................................................................
ABSTRAK......................................................................................................
ABSTRACT....................................................................................................
DAFTAR ISI...................................................................................................
DAFTAR TABEL...........................................................................................
DAFTAR GAMBAR......................................................................................
DAFTAR LAMPIRAN...................................................................................

i
ii
iii
iv
vi
vii
viii
x
xi
xii

BAB I PENDAHULUAN

1.1.
Latar Belakang.........................................................................
1.2.
Identifikasi Masalah.................................................................
1.3.
Maksud dan Tujuan Penelitian...........................................
1.3.1. Maksud Penelitian...............................................................
1.3.2. Tujuan Penelitian................................................................
1.4.
Manfaat Penelitian ............................................................
1.4.1 Manfaat Akademis...............................................................
1.4.2. Manfaat praktis...................................................................
1.5.
Landasan Teoritis...............................................................
1.6.
Metodologi.....................................................................................
1.7.
Lokasi dan Waktu Penelitian..............................................

1

1
2
2
2
3
3
3
3
4
4

BAB II TINJAUAN PUSTAKA
2.1.
Ovarium.............................................................................
2.1.1. Anatomi Ovarium..................................................................
2.1.2. Histologi ...............................................................................
2.2.
Kanker Ovarium.................................................................
2.2.1. Definisi.................................................................................
2.2.2. Insidensi dan Epidemiologi..................................................

2.2.3. Etiologi.................................................................................
2.2.4. Faktor Risiko........................................................................
2.2.5. Klasifikasi.............................................................................
2.2.5.1. Neoplasma Sel Epitel (Epithelial Neoplasms).......
2.2.5.2. Neoplasma Sel Germinal.......................................
2.2.5.3. Neoplasma Sex-cord stromal.................................
2.2.5.4. Metastase Kanker ke Ovarium..............................
2.2.6. Gejala Klinik........................................................................
2.2.7. Diagnosis..............................................................................
2.2.8. Stadium Klinik......................................................................
2.2.9. Terapi....................................................................................
2.2.10. Prognosis............................................................................

5
5
8
10
10
10
11

12
15
16
17
20
21
22
23
24
26
27

viii

BAB III METODE PENELITIAN
3.1.
Metode Penelitian...........................................................................
3.2.
Rancangan Penelitian.....................................................................
3.3.

Teknik Pengambilan Data..............................................................
3.4.
Instrumen Penelitian.......................................................................
3.5.
Sampel Penelitian...........................................................................
3.6.
Kriteria Sampel Penelitian..............................................................
3.6.1. Kriteria Inklusi......................................................................
3.6.2. Kriteria Ekslusi.....................................................................
3.7. Alur Penelitian.................................................................................
3.8. Teknik Analisis Data.......................................................................
BAB IV HASIL DAN PEMBAHASAN
4.1.
Distribusi Kanker Ovarium Berdasarkan Golongan Usia..............
4.2.
Distribusi Kanker Ovarium Berdasarkan Paritas...........................
4.3.
Distribusi Kanker Ovarium Berdasarkan Keluhan Utama
Penderita.........................................................................................
4.4.

Distribusi Kanker Ovarium Berdasarkan Jenis Kanker
Ovarium..........................................................................................
4.5.
Distribusi Kanker Ovarium Berdasarkan Stadium Kanker
Ovarium yang Diderita...................................................................
4.6.
Distribusi Kanker Ovarium Berdasarkan terapi yang
Diberikan........................................................................................

29
29
29
29
29
30
30
30
30
30

31
32
33
35
36
37

BAB V SIMPULAN DAN SARAN
5.1.
Simpulan.........................................................................................
5.2.
Saran...............................................................................................

39
39

DAFTAR PUSTAKA.....................................................................................
LAMPIRAN....................................................................................................
RIWAYAT PENULIS....................................................................................

40
41
52

ix

DAFTAR TABEL
Halaman
Tabel 2.1
Tabel 2.2.
Tabel 4.1.
Tabel 4.2.
Tabel 4.3.
Tabel 4.4.
Tabel 4.5.
Tabel 4.6.

Kriteria Stadium Kanker Ovarium menurut FIGO....
5-year survival rate Kanker Epitel Ovarium
menurut Stadium FIGO.........................................
Distribusi Kanker Ovarium Berdasarkan Golongan
Usia.....................................................................
Distribusi Kanker Ovarium Berdasarkan Paritas.......
Distribusi Kanker Ovarium Berdasarkan Keluhan
Utama Penderita...................................................
Distribusi Kanker Ovarium Berdasarkan Jenis
Kanker Ovarium...................................................
Distribusi Kanker Ovarium Berdasarkan Stadium
Kanker Ovarium yang Diderita..............................
Distribusi Kanker Ovarium Berdasarkan terapi yang
Diberikan.............................................................

x

25
28
31
32
33
35
36
37

DAFTAR GAMBAR
Halaman
Gambar 2.1.
Gambar 2.2.
Gambar 2.3.

Ovarium dan hubungannya dengan ligamentum
latum...................................................................
Pembuluh darah ovarium.......................................
Klasifikasi keganasan ovarium dan distribusi
frekuensi kejadian dan umur penderita....................

xi

6
7
15

DAFTAR LAMPIRAN
Halaman
Lampiran 1 Data Rekam Medik Pasien Kanker Ovarium di Rumah
Sakit Hasan Sadikin Bandung Periode Januari 2011Desember 2011....................................................
Lampiran 2 Surat Izin Pengambilan Data di Bagian Rekam Medik
Rumah Sakit Hasan Sadikin Bandung..........................

xii

43
51

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