Reference Efek Jamur Tiram Putih (Pleurotus Ostreatus) Terhadap Sel Beta Pankreas Tikus Wistar Jantan Model Diabetes Mellitus Tipe 2 Yang Diberi Pakan Tinggi Lemak Dan Dosis Rendah
73
DAFTAR PUSTAKA
Abrefah, R G, E Mensimah, N S Opata, and K Gyamfi. 2011. “Determination of
the Concentration of Essential Elements in Pleurotus Ostreatus Cultivated on
Valisneria Arthiopica as a Supplementary Substrate to Sawdust Using
Instrumental Neutron Activation Analyses”. Res. J. Appl. Sci. Eng. Technol 3
(11): 1296–1301.
Al-Dahr, MHS, and EH Jiffri. 2010. “Increased Adipose Tissue Expression of
Tumor Necrosis Factor-alpha and Insulin Resistance in Obese Subjects with
Type II Diabetes.” World Journal of Medical Sciences 5 (2): 30–35.
Alam, Nuhu, Ki Nam Yoon, Tae Soo Lee, and U Youn Lee. 2011.
“Hypolipidemic Activities of Dietary Pleurotus Ostreatus in
Hypercholesterolemic Rats.” Mycobiology 39 (1) (March): 45–51.
Alam, Nuhu, KN Yoon, and KR Lee. 2010. “Antioxidant Activities and
Tyrosinase Inhibitory Effects of Different Extracts from Pleurotus Ostreatus
Fruiting Bodies.” Mycobiology 38 (4): 295–301.
Alberti, KGMM, P Zimmet, and J Shaw. 2007. “International Diabetes
Federation: A Consensus on Type 2 Diabetes Prevention.” Diabetic
Medicine, 451–63.
Al-deen, Ihsan HS, Husni AA Twaij, Ammar A AL-Badr, and Tahsin AW
Istarabadi. 1987. “Toxicologic and Histopathologic Studies of Pleurotus
Ostreatus Mushroom in Mice”. Journal of Ethnopharmacology 21: 297–305.
Agrawal, R. & Chopra, A., 2010. Effect of oyster mushroom on glycemia, lipid
profile and quality of life in type 2 diabetic patients. Australian Journal of
Medical Herbalism 22(2).
Barag, SH. 2011. “Insulin Therapy for Management of Type 2 Diabetes Mellitus:
Strategies for Initiation and Long-Term Patient Adherence.” JAOA: Journal
of the American Osteopathic … 111 (7): 13–19.
Bhattacharya, Samir, Debleena Dey, and Sib Sankar Roy. 2007. “Molecular
Mechanism of Insulin Resistance.” Journal of Biosciences 32 (2) (March):
405–13.
Bhatti, MI, MM Jiskani, and KH Wagan. 2007. “Growth, Development and Yield
of Oyster Mushroom, Pleurotus Ostreatus (JACQ. EX. FR.) Kummer as
Affected by Different Spawn Rates.” Pak. J. Bot 39 (7): 2685–2692.
Universitas Sumatera Utara
74
Bi, Yufang, Tiange Wang, Min Xu, Y Xu, and Mian Li. 2012. “Advanced
Research on Risk Factors of Type 2 Diabetes.” Diabetes Metab Res Rev 28
(February): 32–39.
Chen, Lei, DJ Magliano, and PZ Zimmet. 2011. “The Worldwide Epidemiology
of Type 2 Diabetes Mellitus—present and Future Perspectives.” Nature
Reviews Endocrinology 8 (4): 228–236.
Chirinang, Pornariya, and Kanok-orn Intarapichet. 2009. “Amino Acids and
Antioxidant Properties of the Oyster Mushrooms , Pleurotus Ostreatus and
Pleurotus Sajor-caju.” Science Asia 35: 326–331.
Choi, Hyon K., Walter C. Willett, Meir J. Stampfer, Eric Rimm, and Frank B. Hu.
2005. “Dairy Consumption and Risk of Type 2 Diabetes Mellitus in Men.”
Arch Intern Med 165: 997–1003.
Choudhury, MBK, and T Rahman. 2013. “Effects of Pleurotus Ostreatus on Blood
Pressure and Glycemic Status of Hypertensive Diabetic Male Volunteers.”
Bangladesh Journal of Med Biochem: 5–10.
Drake, Richard L, Wayne Vogl, and Adam M W Mitchell. 2007. Gray’s Anatomy
for Students. Elsevier.
DeFronzo, R. (1999). Pharmacologic therapy for type 2 diabetes mellitus. Annals
of internal medicine, 281–303.
Eckel, R.H. et al., 2011. Obesity and type 2 diabetes: what can be unified and
what needs to be individualized? Diabetes care, 34(6), pp.1424–30.
Ellis, Harold. 2006. Clinical Anatomy. Annals of Surgery. 11th ed. Vol. 159.
Oxford: Blackwell Publishing.
Evans, J. L., Ira D Goldfine, Betty A Maddux, and Gerold M Grodsky. 2002.
“Oxidative Stress and Stress-Activated Signaling Pathways: A Unifying
Hypothesis of Type 2 Diabetes.” Endocrine Reviews 23 (5) (October 1): 599–
622.
Faller, Adolf, Michael Schünke, and Gabriele Schünke. 2004. The Human Body.
New York: Thieme.
Fernández-Mejía, C. 2013. “Oxidative Stress in Diabetes Mellitus and the Role Of
Vitamins with Antioxidant Actions.” Diseases-A Role For Antioxidants.
Finkel, T. (2011). Signal transduction by reactive oxygen species. The Journal of
cell biology, 194(1), 7–15.
Universitas Sumatera Utara
75
Gardner, David G., and Dolores Shoback. 2007. Greenspan’s Basic & Clinical
Endocrinology. Ed. James F. Shanahan and Peter J. Boyle. 9th ed. San
Fransisco: The McGraw-Hill Companies.
Ghaly, IS, ES Ahmed, and HF Booles. 2011. “Oyster Mushroom (Pleurotus
Ostreatus) and Its Effect on DNA Damage, Chromosome Aberrations and
Sperm Abnormalities in Streptozotocin-induced Diabetic Rats.” Global
Veterinaria 7 (6): 532–544.
Glass, C. & Olefsky, J., 2012. Inflammation and lipid signaling in the etiology of
insulin resistance. Cell Metabolism, 15(5), pp.635–645.
Goldman, Lee, and J. Claude Bennet. 2000. Cecil Textbook of Medicine. 21st Ed.
Jeffrey M. Drazen, Gordon L. Gill, Robert C. Griggs, Juha P. Kokko, Gerald
L. Mandell, Don W. Powell, and Andrew I. Schafer. 21st ed. Philadelphia:
W.B. Saunders Company.
Gunawan, Agustin Widya. 2008. Usaha Pembibitan Jamur. Jakarta: PT Penebar
Swadaya.
Guyton, Arthur C, and John E Hall. 2006. Text Book of Medical Physiology. 11th
ed. Philadelphia, Pennsylvania: Elsevier Saunders.
Hajer, Gideon R, Timon W van Haeften, and Frank L J Visseren. 2008. “Adipose
Tissue Dysfunction in Obesity, Diabetes, and Vascular Diseases.” European
Heart Journal 29 (24) (December): 2959–71.
Harris, M.I., 2004. Definition and Classification of Diabetes Mellitus and The
Criteria for Diagnosis. In: D. LeRoith, S.I. Taylor, J.M. Olefsky (Eds.).
Diabetes Mellitus, A Fundamental and Clinical Text, Ed. 3rd, Lippincott
Williams & Wilkins, Philadelphia, pp.458–72
Harrison, Tinsley R. 2005. Harrison’s Principles of Internal Medicine. Ed. Dennis
L. Kasper, Anthony S. Fauci, Dan L. Longo, Eugene Braunwald, Stephen L.
Hauser, and J. Larry Jameson. 16th ed. San Fransisco: The McGraw-Hill
Companies, Inc.
Ibrahim, M Mohsen. 2010. “Subcutaneous and Visceral Adipose Tissue:
Structural and Functional Differences.” Obesity Reviews : an Official Journal
of the International Association for the Study of Obesity 11 (1) (January): 11–
8.
Ikrimah, D. & Permatasari, N., 2012. Inovasi Pengembangan Terapi AutoRegenerasi Berbasis Mobilisasi Hematopoietic Stem Cell Pada Mencit Model
DM Menggunakan Ekstrak Jamur Tiram (Pleurotus ostreatus).
Universitas Sumatera Utara
76
Isai, M, R Elanchezhian, M Sakthivel, a Chinnakkaruppan, M Rajamohan, C
Nelson Jesudasan, P a Thomas, and P Geraldine. 2009. “Anticataractogenic
Effect of an Extract of the Oyster Mushroom, Pleurotus Ostreatus, in an
Experimental Animal Model.” Current Eye Research 34 (4) (April): 264–73.
Ismail-Beigi, F. 2012. “Glycemic Management of Type 2 Diabetes Mellitus.”
New England Journal of Medicine.
http://www.nejm.org/doi/full/10.1056/nejmcp1013127
Iwalokun, BA, and UA Usen. 2007. “Comparative Phytochemical Evaluation,
Antimicrobial and Antioxidant Properties of Pleurotus Ostreatus.” African
Journal of Biotechnology 6 (August): 1732–1739.
Jayakumar, T, E Ramesh, and P Geraldine. 2006. “Antioxidant Activity of the
Oyster Mushroom, Pleurotus Ostreatus, on CCl(4)-Induced Liver Injury in
Rats.” Food and Chemical Toxicology : An International Journal Published
for the British Industrial Biological Research Association 44 (12): 1989–96.
doi:10.1016/j.fct.2006.06.025.
Jayakumar, Thanasekaran, Philip Aloysius Thomas, Mathivanan Isai, and
Pitchairaj Geraldine. 2010. “An Extract of the Oyster Mushroom, Pleurotus
Ostreatus, Increases Catalase Gene Expression and Reduces Protein
Oxidation During Aging in Rats.” Zhong Xi Yi Jie He Xue Bao = Journal of
Chinese Integrative Medicine.
Jonathan, SG, and CB Oko. 2012. “Nutritional Values of Oyster Mushroom
(Pleurotus ostreatus)(Jacq. Fr.) Kumm. Cultivated on Different Agricultural
Wastes.” Nature and Science 10 (9).
Jung, Ji Young, Yeni Lim, Min Sun Moon, Ji Yeon Kim, and Oran Kwon. 2011.
“Onion Peel Extracts Ameliorate Hyperglycemia and Insulin Resistance in
High Fat Diet/streptozotocin-induced Diabetic Rats.” Nutrition & Metabolism
8 (1) (January): 18.
Kakkar, Rakesh, SV Mantha, and Jasim Radhi. 1998. “Increased Oxidative Stress
in Rat Liver and Pancreas during Progression of Streptozotocin-Induced
Diabetes.” Clinical Science 632 (94): 623–32.
Kaneto, Hideaki, Naoto Katakami, Munehide Matsuhisa, and Taka-aki Matsuoka.
2010. “Role of Reactive Oxygen Species in the Progression of Type 2
Diabetes and Atherosclerosis.” Mediators of Inflammation 2010 (January):
453892.
Kasuga, Masato. 2006. “Insulin Resistance and Pancreatic
of Clinical Investigation 116 (7).
Cell Failure.” Journal
Universitas Sumatera Utara
77
El Khoury, D, C Cuda, B L Luhovyy, and G H Anderson. 2012. “Beta Glucan:
Health Benefits in Obesity and Metabolic Syndrome.” Journal of Nutrition
and Metabolism 2012 (January): 851362.
Kim, JH, SJ Kim, and HR Park. 2009. “The Different Antioxidant and Anticancer
Activities Depending on the Color of Oyster Mushrooms.” Journal of
Medicinal Plants Research 3 (12): 1016–1020.
Kim, HS, JA Shin, and JS Chang. 2012. “Continuous Glucose Monitoring:
Current Clinical Use.” Diabetes/metabolism … 28 (December 2011): 73–78.
Klein, Samuel, Nancy F Sheard, Xavier Pi-Sunyer, Anne Daly, Judith WylieRosett, Karmeen Kulkarni, and Nathaniel G Clark. 2005. “Weight
Management Using Lifestyle Modification in the Prevention and
Management of Type 2 Diabetes: Rationale and Strategies.” … Diabetes 27
(8): 2067–73.
Koolman, Jan, and KH Röhm. 2005. Color Atlas of Biochemistry. Ed. Jan
Koolman and Klaus-Heinrich Roehm. 2nd ed. New York: Thieme.
Krishna, LS, PTA Usha, and AM Nair. 2009. “Hypoglycaemic Effect of Pleurotus
Ostreatus in Rats.” Indian Journal of Animal Research 43 (2): 139–141.
Kuehnel, Wolfgang. 2003. Cytology, Histology and Microscopic Anatomy of
Humans. Ed. Wolfgang Kuehnel. Berne, Switzerland: Hans Huber. 4th ed.
Stuttgart: Thieme.
Kumar, Vinay, Abul K Abbas, Nelson Fausto, and Jon C Aster. 2010. Robbins &
Cotran Pathologic Basis of Disease. 8th ed. Saunders Elsevier.
Kurniasari, D. 2012. “Perbedaan Kadar Glukosa Darah pada Tikus Wistar Jantan
(Rattus norvegicus) Setelah Terpapar Stresor Renjatan Listrik.”
Lenzen, Sigurd. 2007. “Alloxan and Streptozotocin Diabetes.” Endokrinologie III
Vorträge Im Rahmen Des Projektes.
Li, X, X Wang, S Chen, and D Chen. 2011. “Antioxidant Activity and Mechanism
of Protocatechuic Acid in Vitro.” Functional Foods in Health and Disease 50:
232–244.
Lichtenstein, A H, and U S Schwab. 2000. “Relationship of Dietary Fat to
Glucose Metabolism.” Atherosclerosis 150 (2) (June): 227–43.
Lin, Hui-Hsuan, Jing-Hsien Chen, Fen-Pi Chou, and Chau-Jong Wang. 2011.
“Protocatechuic Acid Inhibits Cancer Cell Metastasis Involving the Downregulation of Ras/Akt/NF- B Pathway and MMP-2 Production by Targeting
Universitas Sumatera Utara
78
RhoB Activation.” British Journal of Pharmacology 162 (1) (January): 237–
54.
Marshall, JA, and DH Bessesen. 2002. “Dietary Fat and the Development of Type
2 Diabetes.” Diabetes Care 25 (3).
McPhee, Stephen J., and William F. Ganong. 2006. Pathophysiology of Disease:
An Introduction to Clinical Medicine. 5th ed. The McGraw-Hill Companies,
Inc.
Meyer, KA, LH Kushi, DR Jacobs, and AR Folsom. 2001. “Dietary Fat and
Incidence of Type 2 Diabetes in Older Iowa Women.” Diabetes Care (June
2000).
Moore, Keith L, and Anne M R Agur. 2007. Essential Clinical Anatomy. 3rd ed.
Toronto, Canada: Lippincot William & Wilkins.
Murray, Robert K, Daryl K Granner, and Victor W Rodwell. 2006. Harpers
Illustrated Biochemistry. 27th ed. McGraw Hill.
Nakamura, Tomonori, Tomoko Terajima, Taeko Ogata, Koichi Ueno, Naotake
Hashimoto, Kageyoshi Ono, and Shingo Yano. 2006. “Establishment and
Pathophysiological Characterization of Type 2 Diabetic Mouse Model
Produced by Streptozotocin and Nicotinamide.” Biological & Pharmaceutical
Bulletin 29 (6) (June): 1167–74.
Nathan, DM, JB Buse, and MB Davidson. 2009. “Medical Management of
Hyperglycaemia in Type 2 Diabetes Mellitus: A Consensus Algorithm for the
Initiation and Adjustment of Therapy.” Diabetologia, 17–30.
Neelam, Sridevi, and Summer Singh. 2013. “Comparative Studies on Antioxidant
Capacity of Ethanol Extracts of Pleurotus Florida and Pleurotus Ostreatus.”
Scholarsresearchlibrary.com 4 (4): 77–82.
Neldawati. 2006. “Studi Senyawa Bioaktif Eksopolisakarida Pleurotus Ostreatus
Pada Media Cair Dengan Berbagai Macam Sumber Karbon.”
Niemelä, S., & Miettinen, S. (2008). Adipose tissue and adipocyte differentiation:
Molecular and cellular aspects and tissue engineering applications. Topics in
Tissue Engineering, 4.
Nosál’ová, V, P Bobek, S Cerná, S Galbavý, and S Stvrtina. 2001. “Effects of
Pleuran (beta-glucan Isolated from Pleurotus Ostreatus) on Experimental
Colitis in Rats.” Physiological Research / Academia Scientiarum
Bohemoslovaca 50 (6) (January): 575–81.
Universitas Sumatera Utara
79
Ong, Khang Wei, Annie Hsu, and Benny Kwong Huat Tan. 2012. “Chlorogenic
Acid Stimulates Glucose Transport in Skeletal Muscle via AMPK Activation:
a Contributor to the Beneficial Effects of Coffee on Diabetes.” PloS One 7 (3)
(January): e32718.
Patel, Y., Naraian, R. & Singh, V., 2012. Medicinal Properties of Pleurotus
Species (Oyster Mushroom): A Review. World, 3(1), pp.1–12.
Parveen, Kehkashan, Rashid Khan, and WA Siddiqui. 2011. “Antidiabetic Effects
Afforded by Terminalia Arjuna in High Fat-fed and Streptozotocin-induced
Type 2 Diabetic Rats.” International Journal of Diabetes : 23–33
Ragbetli, Cennet, and Ceylan. Ebubekir. 2010. “Effect of Streptozotocin on
Biochemical Parameters in Rats.” Asian Journal of Chemistry 22 (3): 2375–
2378.
Ramachandran, A. & Snehalatha, C., 2012. Trends in prevalence of diabetes in
Asian countries. World Journal of Diabetes, 3(6), pp.110–117.
Rathee, S. & Rathee, D., 2012. Mushrooms as therapeutic agents. Revista
Brasileira de Farmacognosia, pp.459–474.
Rato, LM, and F Capela e Silva. 2013. “Analysis of Pancreas Histological Images
for Glucose Intolerance Identificationusing ImageJ-Preliminary Results.”
Reis, Filipa S, Anabela Martins, Lillian Barros, and Isabel C F R Ferreira. 2012.
“Antioxidant Properties and Phenolic Profile of the Most Widely Appreciated
Cultivated Mushrooms: a Comparative Study Between in Vivo and in Vitro
Samples.” Food and Chemical Toxicology : an International Journal
Published for the British Industrial Biological Research Association 50 (5)
(May): 1201–7.
Risérus, U., Willett, W. & Hu, F., 2009. Dietary fats and prevention of type 2
diabetes. Progress in lipid research, 48(1), pp.44–51.
Rovenský, Jozef, M Stan íkova, K Svík, K Bauerová, and J Jur ovi ová. 2011.
“The Effects of -glucan Isolated from Pleurotus Ostreatus on Methotrexate
Treatment in Rats with Adjuvant Arthritis.” Rheumatology International.
Saini, Vandana. 2010. “Molecular Mechanisms of Insulin Resistance in Type 2
Diabetes Mellitus.” World Journal of Diabetes 1 (3) (July 15): 68–75.
Schneider, Inga, Gaby Kressel, Annette Meyer, Ulrich Krings, Ralf G Berger, and
Andreas Hahn. 2011. “Lipid Lowering Effects of Oyster Mushroom
(Pleurotus Ostreatus) in Humans.” Journal of Functional Foods 3 (1)
(January): 17–24.
Universitas Sumatera Utara
80
Silva, D. De et al., 2012. Medicinal mushrooms in prevention and control of
diabetes mellitus. Fungal Diversity, pp.1–29.
Szkudelski, T. 2001. “The Mechanism of Alloxan and Streptozotocin Action in B
Cells of the Rat Pancreas.” Physiological Research 50: 536–46.
Smirnov, AV, GL Snigur, and MP Voronkova. 2012. “Pancreatic Islet Beta-Cell
Apoptosis in Experimental Diabetes Mellitus”, 225–46. doi:10.5772/51411.
Snel, M., Jonker, J. & Schoones, J., 2012. Ectopic fat and insulin resistance:
pathophysiology and effect of diet and lifestyle interventions. International
Journal of Endocrinology, 2012.
Son, Seok Man. 2012. “Reactive Oxygen and Nitrogen Species in Pathogenesis of
Vascular Complications of Diabetes.” Diabetes & Metabolism Journal 36 (3)
(June): 190–8.
Srinivasan, K., Viswanad, B. & Asrat, L., 2005. Combination of high-fat diet-fed
and low-dose streptozotocin-treated rat: a model for type 2 diabetes and
pharmacological screening. Pharmacological Research, 52, pp.313–320.
Syariefa, Evi, Destika Cahyana, Dian Adijaya Susanto, Sardi Duryatmo, and
Imam Wiguna. 2010. Jamur Tiram Dua Alam. Vol. 5. Jakarta: PT Trubus
Swadaya.
Synytsya, Andriy, Kate ina Mí ková, Alla Synytsya, Ivan Jablonský, Ji í
Sp vá ek, Vladimír Erban, Eliška Ková íková, and Jana opíková. 2009.
“Glucans from Fruit Bodies of Cultivated Mushrooms Pleurotus Ostreatus
and Pleurotus Eryngii: Structure and Potential Prebiotic Activity.”
Carbohydrate Polymers 76 (4) (May): 548–556.
Tataranni, P., 2002. Pathophysiology of obesity-induced insulin resistance and
type 2 diabetes mellitus. European review for medical and pharmacological
sciences, pp.27–32.
Tian, HL, LS Wei, ZX Xu, RT Zhao, DL Jin, and JS Gao. 2010. “Correlations
Between Blood Glucose Level and Diabetes Signs in Streptozotocin Induced
Diabetic Mice.” Global J Pharmacol.
Trayhurn, Paul, and I Stuart Wood. 2004. “Adipokines: Inflammation and the
Pleiotropic Role of White Adipose Tissue.” The British Journal of Nutrition
92 (3) (September): 347–55.
Ugarte, Marta, Marie Brown, and KA Hollywood. 2012. “Metabolomic Analysis
of Rat Serum in Streptozotocin-Induced Diabetes and after Treatment with
Universitas Sumatera Utara
81
Oral Triethylenetetramine (TETA).” Genome … 4 (4). BioMed Central Ltd:
AA. http://genomemedicine.com/content/4/4/AA
Vamanu, E, M Ene, and A Vamanu. 2011. “Antioxidant and Antibacterial
Properties of the Extracts from Pleurotus Ostreatus EVFB1 and EVFB4.”
Romanian Biotechnological Letters 16 (1): 40–46.
Wang, Hui Jie, Yuan Xiang Jin, Wan Shen, Jing Neng, Tao Wu, Yong Jie Li, and
Zheng Wei Fu. 2007. “Low Dose Streptozotocin (STZ) Combined with High
Energy Intake Can Effectively Induce Type 2 Diabetes Through Altering the
Related Gene Expression.” Asia Pacific Journal of Clinical Nutrition 16
Suppl 1 (Suppl 1) (January): 412–7.
Wang, Zhiyong, and Helga Gleichmann. 1998. “GLUT2 in Pancreatic Islets:
Crucial Target Molecule in Diabetes Induced with Multiple Low Doses of
Streptozotocin in Mice.” Diabetes 47 (January).
Wei, Michael, Leslie Ong, Maree T Smith, Fraser B Ross, Katrina Schmid,
Andrew J Hoey, Darryl Burstow, and Lindsay Brown. 2003. “The
Streptozotocin-diabetic Rat as a Model of the Chronic Complications of
Human Diabetes.” Heart, Lung & Circulation 12 (1) (January): 44–50.
[WHO]. World Health Organization. 2013, March.
Wilcox, Gisela. 2005. “Insulin and Insulin Resistance.” The Clinical Biochemist.
Reviews / Australian Association of Clinical Biochemists 26 (2) (May): 19–
39.
Wild, S. et al., 2004. Global prevalence of diabetes estimates for the year 2000
and projections for 2030. Diabetes care, 27(5).
Wolf, G., 2008. Role of fatty acids in the development of insulin resistance and
type 2 diabetes mellitus. Nutrition reviews, 66(10), pp.597–600.
Wyness, Laura. 2009. “Understanding the Role of Diet in Type 2 Diabetes
Prevention.” British Journal of Community Nursing 14 (9).
Yoon, Kun-ho, Jin-hee Lee, Ji-won Kim, Jae Hyoung Cho, Yoon-hee Choi,
Seung-hyun Ko, Paul Zimmet, and Ho-young Son. 2006. “Epidemic Obesity
and Type 2 Diabetes in Asia” www.thelancet.com 368: 1681–1688.
Zhang, Ming, Xiao-Yan Lv, Jing Li, Zhi-Gang Xu, and Li Chen. 2008. “The
Characterization of High-Fat Diet and Multiple Low-Dose Streptozotocin
Induced Type 2 Diabetes Rat Model.” Experimental Diabetes Research 2008
(January): 704045. doi:10.1155/2008/704045.
Universitas Sumatera Utara
DAFTAR PUSTAKA
Abrefah, R G, E Mensimah, N S Opata, and K Gyamfi. 2011. “Determination of
the Concentration of Essential Elements in Pleurotus Ostreatus Cultivated on
Valisneria Arthiopica as a Supplementary Substrate to Sawdust Using
Instrumental Neutron Activation Analyses”. Res. J. Appl. Sci. Eng. Technol 3
(11): 1296–1301.
Al-Dahr, MHS, and EH Jiffri. 2010. “Increased Adipose Tissue Expression of
Tumor Necrosis Factor-alpha and Insulin Resistance in Obese Subjects with
Type II Diabetes.” World Journal of Medical Sciences 5 (2): 30–35.
Alam, Nuhu, Ki Nam Yoon, Tae Soo Lee, and U Youn Lee. 2011.
“Hypolipidemic Activities of Dietary Pleurotus Ostreatus in
Hypercholesterolemic Rats.” Mycobiology 39 (1) (March): 45–51.
Alam, Nuhu, KN Yoon, and KR Lee. 2010. “Antioxidant Activities and
Tyrosinase Inhibitory Effects of Different Extracts from Pleurotus Ostreatus
Fruiting Bodies.” Mycobiology 38 (4): 295–301.
Alberti, KGMM, P Zimmet, and J Shaw. 2007. “International Diabetes
Federation: A Consensus on Type 2 Diabetes Prevention.” Diabetic
Medicine, 451–63.
Al-deen, Ihsan HS, Husni AA Twaij, Ammar A AL-Badr, and Tahsin AW
Istarabadi. 1987. “Toxicologic and Histopathologic Studies of Pleurotus
Ostreatus Mushroom in Mice”. Journal of Ethnopharmacology 21: 297–305.
Agrawal, R. & Chopra, A., 2010. Effect of oyster mushroom on glycemia, lipid
profile and quality of life in type 2 diabetic patients. Australian Journal of
Medical Herbalism 22(2).
Barag, SH. 2011. “Insulin Therapy for Management of Type 2 Diabetes Mellitus:
Strategies for Initiation and Long-Term Patient Adherence.” JAOA: Journal
of the American Osteopathic … 111 (7): 13–19.
Bhattacharya, Samir, Debleena Dey, and Sib Sankar Roy. 2007. “Molecular
Mechanism of Insulin Resistance.” Journal of Biosciences 32 (2) (March):
405–13.
Bhatti, MI, MM Jiskani, and KH Wagan. 2007. “Growth, Development and Yield
of Oyster Mushroom, Pleurotus Ostreatus (JACQ. EX. FR.) Kummer as
Affected by Different Spawn Rates.” Pak. J. Bot 39 (7): 2685–2692.
Universitas Sumatera Utara
74
Bi, Yufang, Tiange Wang, Min Xu, Y Xu, and Mian Li. 2012. “Advanced
Research on Risk Factors of Type 2 Diabetes.” Diabetes Metab Res Rev 28
(February): 32–39.
Chen, Lei, DJ Magliano, and PZ Zimmet. 2011. “The Worldwide Epidemiology
of Type 2 Diabetes Mellitus—present and Future Perspectives.” Nature
Reviews Endocrinology 8 (4): 228–236.
Chirinang, Pornariya, and Kanok-orn Intarapichet. 2009. “Amino Acids and
Antioxidant Properties of the Oyster Mushrooms , Pleurotus Ostreatus and
Pleurotus Sajor-caju.” Science Asia 35: 326–331.
Choi, Hyon K., Walter C. Willett, Meir J. Stampfer, Eric Rimm, and Frank B. Hu.
2005. “Dairy Consumption and Risk of Type 2 Diabetes Mellitus in Men.”
Arch Intern Med 165: 997–1003.
Choudhury, MBK, and T Rahman. 2013. “Effects of Pleurotus Ostreatus on Blood
Pressure and Glycemic Status of Hypertensive Diabetic Male Volunteers.”
Bangladesh Journal of Med Biochem: 5–10.
Drake, Richard L, Wayne Vogl, and Adam M W Mitchell. 2007. Gray’s Anatomy
for Students. Elsevier.
DeFronzo, R. (1999). Pharmacologic therapy for type 2 diabetes mellitus. Annals
of internal medicine, 281–303.
Eckel, R.H. et al., 2011. Obesity and type 2 diabetes: what can be unified and
what needs to be individualized? Diabetes care, 34(6), pp.1424–30.
Ellis, Harold. 2006. Clinical Anatomy. Annals of Surgery. 11th ed. Vol. 159.
Oxford: Blackwell Publishing.
Evans, J. L., Ira D Goldfine, Betty A Maddux, and Gerold M Grodsky. 2002.
“Oxidative Stress and Stress-Activated Signaling Pathways: A Unifying
Hypothesis of Type 2 Diabetes.” Endocrine Reviews 23 (5) (October 1): 599–
622.
Faller, Adolf, Michael Schünke, and Gabriele Schünke. 2004. The Human Body.
New York: Thieme.
Fernández-Mejía, C. 2013. “Oxidative Stress in Diabetes Mellitus and the Role Of
Vitamins with Antioxidant Actions.” Diseases-A Role For Antioxidants.
Finkel, T. (2011). Signal transduction by reactive oxygen species. The Journal of
cell biology, 194(1), 7–15.
Universitas Sumatera Utara
75
Gardner, David G., and Dolores Shoback. 2007. Greenspan’s Basic & Clinical
Endocrinology. Ed. James F. Shanahan and Peter J. Boyle. 9th ed. San
Fransisco: The McGraw-Hill Companies.
Ghaly, IS, ES Ahmed, and HF Booles. 2011. “Oyster Mushroom (Pleurotus
Ostreatus) and Its Effect on DNA Damage, Chromosome Aberrations and
Sperm Abnormalities in Streptozotocin-induced Diabetic Rats.” Global
Veterinaria 7 (6): 532–544.
Glass, C. & Olefsky, J., 2012. Inflammation and lipid signaling in the etiology of
insulin resistance. Cell Metabolism, 15(5), pp.635–645.
Goldman, Lee, and J. Claude Bennet. 2000. Cecil Textbook of Medicine. 21st Ed.
Jeffrey M. Drazen, Gordon L. Gill, Robert C. Griggs, Juha P. Kokko, Gerald
L. Mandell, Don W. Powell, and Andrew I. Schafer. 21st ed. Philadelphia:
W.B. Saunders Company.
Gunawan, Agustin Widya. 2008. Usaha Pembibitan Jamur. Jakarta: PT Penebar
Swadaya.
Guyton, Arthur C, and John E Hall. 2006. Text Book of Medical Physiology. 11th
ed. Philadelphia, Pennsylvania: Elsevier Saunders.
Hajer, Gideon R, Timon W van Haeften, and Frank L J Visseren. 2008. “Adipose
Tissue Dysfunction in Obesity, Diabetes, and Vascular Diseases.” European
Heart Journal 29 (24) (December): 2959–71.
Harris, M.I., 2004. Definition and Classification of Diabetes Mellitus and The
Criteria for Diagnosis. In: D. LeRoith, S.I. Taylor, J.M. Olefsky (Eds.).
Diabetes Mellitus, A Fundamental and Clinical Text, Ed. 3rd, Lippincott
Williams & Wilkins, Philadelphia, pp.458–72
Harrison, Tinsley R. 2005. Harrison’s Principles of Internal Medicine. Ed. Dennis
L. Kasper, Anthony S. Fauci, Dan L. Longo, Eugene Braunwald, Stephen L.
Hauser, and J. Larry Jameson. 16th ed. San Fransisco: The McGraw-Hill
Companies, Inc.
Ibrahim, M Mohsen. 2010. “Subcutaneous and Visceral Adipose Tissue:
Structural and Functional Differences.” Obesity Reviews : an Official Journal
of the International Association for the Study of Obesity 11 (1) (January): 11–
8.
Ikrimah, D. & Permatasari, N., 2012. Inovasi Pengembangan Terapi AutoRegenerasi Berbasis Mobilisasi Hematopoietic Stem Cell Pada Mencit Model
DM Menggunakan Ekstrak Jamur Tiram (Pleurotus ostreatus).
Universitas Sumatera Utara
76
Isai, M, R Elanchezhian, M Sakthivel, a Chinnakkaruppan, M Rajamohan, C
Nelson Jesudasan, P a Thomas, and P Geraldine. 2009. “Anticataractogenic
Effect of an Extract of the Oyster Mushroom, Pleurotus Ostreatus, in an
Experimental Animal Model.” Current Eye Research 34 (4) (April): 264–73.
Ismail-Beigi, F. 2012. “Glycemic Management of Type 2 Diabetes Mellitus.”
New England Journal of Medicine.
http://www.nejm.org/doi/full/10.1056/nejmcp1013127
Iwalokun, BA, and UA Usen. 2007. “Comparative Phytochemical Evaluation,
Antimicrobial and Antioxidant Properties of Pleurotus Ostreatus.” African
Journal of Biotechnology 6 (August): 1732–1739.
Jayakumar, T, E Ramesh, and P Geraldine. 2006. “Antioxidant Activity of the
Oyster Mushroom, Pleurotus Ostreatus, on CCl(4)-Induced Liver Injury in
Rats.” Food and Chemical Toxicology : An International Journal Published
for the British Industrial Biological Research Association 44 (12): 1989–96.
doi:10.1016/j.fct.2006.06.025.
Jayakumar, Thanasekaran, Philip Aloysius Thomas, Mathivanan Isai, and
Pitchairaj Geraldine. 2010. “An Extract of the Oyster Mushroom, Pleurotus
Ostreatus, Increases Catalase Gene Expression and Reduces Protein
Oxidation During Aging in Rats.” Zhong Xi Yi Jie He Xue Bao = Journal of
Chinese Integrative Medicine.
Jonathan, SG, and CB Oko. 2012. “Nutritional Values of Oyster Mushroom
(Pleurotus ostreatus)(Jacq. Fr.) Kumm. Cultivated on Different Agricultural
Wastes.” Nature and Science 10 (9).
Jung, Ji Young, Yeni Lim, Min Sun Moon, Ji Yeon Kim, and Oran Kwon. 2011.
“Onion Peel Extracts Ameliorate Hyperglycemia and Insulin Resistance in
High Fat Diet/streptozotocin-induced Diabetic Rats.” Nutrition & Metabolism
8 (1) (January): 18.
Kakkar, Rakesh, SV Mantha, and Jasim Radhi. 1998. “Increased Oxidative Stress
in Rat Liver and Pancreas during Progression of Streptozotocin-Induced
Diabetes.” Clinical Science 632 (94): 623–32.
Kaneto, Hideaki, Naoto Katakami, Munehide Matsuhisa, and Taka-aki Matsuoka.
2010. “Role of Reactive Oxygen Species in the Progression of Type 2
Diabetes and Atherosclerosis.” Mediators of Inflammation 2010 (January):
453892.
Kasuga, Masato. 2006. “Insulin Resistance and Pancreatic
of Clinical Investigation 116 (7).
Cell Failure.” Journal
Universitas Sumatera Utara
77
El Khoury, D, C Cuda, B L Luhovyy, and G H Anderson. 2012. “Beta Glucan:
Health Benefits in Obesity and Metabolic Syndrome.” Journal of Nutrition
and Metabolism 2012 (January): 851362.
Kim, JH, SJ Kim, and HR Park. 2009. “The Different Antioxidant and Anticancer
Activities Depending on the Color of Oyster Mushrooms.” Journal of
Medicinal Plants Research 3 (12): 1016–1020.
Kim, HS, JA Shin, and JS Chang. 2012. “Continuous Glucose Monitoring:
Current Clinical Use.” Diabetes/metabolism … 28 (December 2011): 73–78.
Klein, Samuel, Nancy F Sheard, Xavier Pi-Sunyer, Anne Daly, Judith WylieRosett, Karmeen Kulkarni, and Nathaniel G Clark. 2005. “Weight
Management Using Lifestyle Modification in the Prevention and
Management of Type 2 Diabetes: Rationale and Strategies.” … Diabetes 27
(8): 2067–73.
Koolman, Jan, and KH Röhm. 2005. Color Atlas of Biochemistry. Ed. Jan
Koolman and Klaus-Heinrich Roehm. 2nd ed. New York: Thieme.
Krishna, LS, PTA Usha, and AM Nair. 2009. “Hypoglycaemic Effect of Pleurotus
Ostreatus in Rats.” Indian Journal of Animal Research 43 (2): 139–141.
Kuehnel, Wolfgang. 2003. Cytology, Histology and Microscopic Anatomy of
Humans. Ed. Wolfgang Kuehnel. Berne, Switzerland: Hans Huber. 4th ed.
Stuttgart: Thieme.
Kumar, Vinay, Abul K Abbas, Nelson Fausto, and Jon C Aster. 2010. Robbins &
Cotran Pathologic Basis of Disease. 8th ed. Saunders Elsevier.
Kurniasari, D. 2012. “Perbedaan Kadar Glukosa Darah pada Tikus Wistar Jantan
(Rattus norvegicus) Setelah Terpapar Stresor Renjatan Listrik.”
Lenzen, Sigurd. 2007. “Alloxan and Streptozotocin Diabetes.” Endokrinologie III
Vorträge Im Rahmen Des Projektes.
Li, X, X Wang, S Chen, and D Chen. 2011. “Antioxidant Activity and Mechanism
of Protocatechuic Acid in Vitro.” Functional Foods in Health and Disease 50:
232–244.
Lichtenstein, A H, and U S Schwab. 2000. “Relationship of Dietary Fat to
Glucose Metabolism.” Atherosclerosis 150 (2) (June): 227–43.
Lin, Hui-Hsuan, Jing-Hsien Chen, Fen-Pi Chou, and Chau-Jong Wang. 2011.
“Protocatechuic Acid Inhibits Cancer Cell Metastasis Involving the Downregulation of Ras/Akt/NF- B Pathway and MMP-2 Production by Targeting
Universitas Sumatera Utara
78
RhoB Activation.” British Journal of Pharmacology 162 (1) (January): 237–
54.
Marshall, JA, and DH Bessesen. 2002. “Dietary Fat and the Development of Type
2 Diabetes.” Diabetes Care 25 (3).
McPhee, Stephen J., and William F. Ganong. 2006. Pathophysiology of Disease:
An Introduction to Clinical Medicine. 5th ed. The McGraw-Hill Companies,
Inc.
Meyer, KA, LH Kushi, DR Jacobs, and AR Folsom. 2001. “Dietary Fat and
Incidence of Type 2 Diabetes in Older Iowa Women.” Diabetes Care (June
2000).
Moore, Keith L, and Anne M R Agur. 2007. Essential Clinical Anatomy. 3rd ed.
Toronto, Canada: Lippincot William & Wilkins.
Murray, Robert K, Daryl K Granner, and Victor W Rodwell. 2006. Harpers
Illustrated Biochemistry. 27th ed. McGraw Hill.
Nakamura, Tomonori, Tomoko Terajima, Taeko Ogata, Koichi Ueno, Naotake
Hashimoto, Kageyoshi Ono, and Shingo Yano. 2006. “Establishment and
Pathophysiological Characterization of Type 2 Diabetic Mouse Model
Produced by Streptozotocin and Nicotinamide.” Biological & Pharmaceutical
Bulletin 29 (6) (June): 1167–74.
Nathan, DM, JB Buse, and MB Davidson. 2009. “Medical Management of
Hyperglycaemia in Type 2 Diabetes Mellitus: A Consensus Algorithm for the
Initiation and Adjustment of Therapy.” Diabetologia, 17–30.
Neelam, Sridevi, and Summer Singh. 2013. “Comparative Studies on Antioxidant
Capacity of Ethanol Extracts of Pleurotus Florida and Pleurotus Ostreatus.”
Scholarsresearchlibrary.com 4 (4): 77–82.
Neldawati. 2006. “Studi Senyawa Bioaktif Eksopolisakarida Pleurotus Ostreatus
Pada Media Cair Dengan Berbagai Macam Sumber Karbon.”
Niemelä, S., & Miettinen, S. (2008). Adipose tissue and adipocyte differentiation:
Molecular and cellular aspects and tissue engineering applications. Topics in
Tissue Engineering, 4.
Nosál’ová, V, P Bobek, S Cerná, S Galbavý, and S Stvrtina. 2001. “Effects of
Pleuran (beta-glucan Isolated from Pleurotus Ostreatus) on Experimental
Colitis in Rats.” Physiological Research / Academia Scientiarum
Bohemoslovaca 50 (6) (January): 575–81.
Universitas Sumatera Utara
79
Ong, Khang Wei, Annie Hsu, and Benny Kwong Huat Tan. 2012. “Chlorogenic
Acid Stimulates Glucose Transport in Skeletal Muscle via AMPK Activation:
a Contributor to the Beneficial Effects of Coffee on Diabetes.” PloS One 7 (3)
(January): e32718.
Patel, Y., Naraian, R. & Singh, V., 2012. Medicinal Properties of Pleurotus
Species (Oyster Mushroom): A Review. World, 3(1), pp.1–12.
Parveen, Kehkashan, Rashid Khan, and WA Siddiqui. 2011. “Antidiabetic Effects
Afforded by Terminalia Arjuna in High Fat-fed and Streptozotocin-induced
Type 2 Diabetic Rats.” International Journal of Diabetes : 23–33
Ragbetli, Cennet, and Ceylan. Ebubekir. 2010. “Effect of Streptozotocin on
Biochemical Parameters in Rats.” Asian Journal of Chemistry 22 (3): 2375–
2378.
Ramachandran, A. & Snehalatha, C., 2012. Trends in prevalence of diabetes in
Asian countries. World Journal of Diabetes, 3(6), pp.110–117.
Rathee, S. & Rathee, D., 2012. Mushrooms as therapeutic agents. Revista
Brasileira de Farmacognosia, pp.459–474.
Rato, LM, and F Capela e Silva. 2013. “Analysis of Pancreas Histological Images
for Glucose Intolerance Identificationusing ImageJ-Preliminary Results.”
Reis, Filipa S, Anabela Martins, Lillian Barros, and Isabel C F R Ferreira. 2012.
“Antioxidant Properties and Phenolic Profile of the Most Widely Appreciated
Cultivated Mushrooms: a Comparative Study Between in Vivo and in Vitro
Samples.” Food and Chemical Toxicology : an International Journal
Published for the British Industrial Biological Research Association 50 (5)
(May): 1201–7.
Risérus, U., Willett, W. & Hu, F., 2009. Dietary fats and prevention of type 2
diabetes. Progress in lipid research, 48(1), pp.44–51.
Rovenský, Jozef, M Stan íkova, K Svík, K Bauerová, and J Jur ovi ová. 2011.
“The Effects of -glucan Isolated from Pleurotus Ostreatus on Methotrexate
Treatment in Rats with Adjuvant Arthritis.” Rheumatology International.
Saini, Vandana. 2010. “Molecular Mechanisms of Insulin Resistance in Type 2
Diabetes Mellitus.” World Journal of Diabetes 1 (3) (July 15): 68–75.
Schneider, Inga, Gaby Kressel, Annette Meyer, Ulrich Krings, Ralf G Berger, and
Andreas Hahn. 2011. “Lipid Lowering Effects of Oyster Mushroom
(Pleurotus Ostreatus) in Humans.” Journal of Functional Foods 3 (1)
(January): 17–24.
Universitas Sumatera Utara
80
Silva, D. De et al., 2012. Medicinal mushrooms in prevention and control of
diabetes mellitus. Fungal Diversity, pp.1–29.
Szkudelski, T. 2001. “The Mechanism of Alloxan and Streptozotocin Action in B
Cells of the Rat Pancreas.” Physiological Research 50: 536–46.
Smirnov, AV, GL Snigur, and MP Voronkova. 2012. “Pancreatic Islet Beta-Cell
Apoptosis in Experimental Diabetes Mellitus”, 225–46. doi:10.5772/51411.
Snel, M., Jonker, J. & Schoones, J., 2012. Ectopic fat and insulin resistance:
pathophysiology and effect of diet and lifestyle interventions. International
Journal of Endocrinology, 2012.
Son, Seok Man. 2012. “Reactive Oxygen and Nitrogen Species in Pathogenesis of
Vascular Complications of Diabetes.” Diabetes & Metabolism Journal 36 (3)
(June): 190–8.
Srinivasan, K., Viswanad, B. & Asrat, L., 2005. Combination of high-fat diet-fed
and low-dose streptozotocin-treated rat: a model for type 2 diabetes and
pharmacological screening. Pharmacological Research, 52, pp.313–320.
Syariefa, Evi, Destika Cahyana, Dian Adijaya Susanto, Sardi Duryatmo, and
Imam Wiguna. 2010. Jamur Tiram Dua Alam. Vol. 5. Jakarta: PT Trubus
Swadaya.
Synytsya, Andriy, Kate ina Mí ková, Alla Synytsya, Ivan Jablonský, Ji í
Sp vá ek, Vladimír Erban, Eliška Ková íková, and Jana opíková. 2009.
“Glucans from Fruit Bodies of Cultivated Mushrooms Pleurotus Ostreatus
and Pleurotus Eryngii: Structure and Potential Prebiotic Activity.”
Carbohydrate Polymers 76 (4) (May): 548–556.
Tataranni, P., 2002. Pathophysiology of obesity-induced insulin resistance and
type 2 diabetes mellitus. European review for medical and pharmacological
sciences, pp.27–32.
Tian, HL, LS Wei, ZX Xu, RT Zhao, DL Jin, and JS Gao. 2010. “Correlations
Between Blood Glucose Level and Diabetes Signs in Streptozotocin Induced
Diabetic Mice.” Global J Pharmacol.
Trayhurn, Paul, and I Stuart Wood. 2004. “Adipokines: Inflammation and the
Pleiotropic Role of White Adipose Tissue.” The British Journal of Nutrition
92 (3) (September): 347–55.
Ugarte, Marta, Marie Brown, and KA Hollywood. 2012. “Metabolomic Analysis
of Rat Serum in Streptozotocin-Induced Diabetes and after Treatment with
Universitas Sumatera Utara
81
Oral Triethylenetetramine (TETA).” Genome … 4 (4). BioMed Central Ltd:
AA. http://genomemedicine.com/content/4/4/AA
Vamanu, E, M Ene, and A Vamanu. 2011. “Antioxidant and Antibacterial
Properties of the Extracts from Pleurotus Ostreatus EVFB1 and EVFB4.”
Romanian Biotechnological Letters 16 (1): 40–46.
Wang, Hui Jie, Yuan Xiang Jin, Wan Shen, Jing Neng, Tao Wu, Yong Jie Li, and
Zheng Wei Fu. 2007. “Low Dose Streptozotocin (STZ) Combined with High
Energy Intake Can Effectively Induce Type 2 Diabetes Through Altering the
Related Gene Expression.” Asia Pacific Journal of Clinical Nutrition 16
Suppl 1 (Suppl 1) (January): 412–7.
Wang, Zhiyong, and Helga Gleichmann. 1998. “GLUT2 in Pancreatic Islets:
Crucial Target Molecule in Diabetes Induced with Multiple Low Doses of
Streptozotocin in Mice.” Diabetes 47 (January).
Wei, Michael, Leslie Ong, Maree T Smith, Fraser B Ross, Katrina Schmid,
Andrew J Hoey, Darryl Burstow, and Lindsay Brown. 2003. “The
Streptozotocin-diabetic Rat as a Model of the Chronic Complications of
Human Diabetes.” Heart, Lung & Circulation 12 (1) (January): 44–50.
[WHO]. World Health Organization. 2013, March.
Wilcox, Gisela. 2005. “Insulin and Insulin Resistance.” The Clinical Biochemist.
Reviews / Australian Association of Clinical Biochemists 26 (2) (May): 19–
39.
Wild, S. et al., 2004. Global prevalence of diabetes estimates for the year 2000
and projections for 2030. Diabetes care, 27(5).
Wolf, G., 2008. Role of fatty acids in the development of insulin resistance and
type 2 diabetes mellitus. Nutrition reviews, 66(10), pp.597–600.
Wyness, Laura. 2009. “Understanding the Role of Diet in Type 2 Diabetes
Prevention.” British Journal of Community Nursing 14 (9).
Yoon, Kun-ho, Jin-hee Lee, Ji-won Kim, Jae Hyoung Cho, Yoon-hee Choi,
Seung-hyun Ko, Paul Zimmet, and Ho-young Son. 2006. “Epidemic Obesity
and Type 2 Diabetes in Asia” www.thelancet.com 368: 1681–1688.
Zhang, Ming, Xiao-Yan Lv, Jing Li, Zhi-Gang Xu, and Li Chen. 2008. “The
Characterization of High-Fat Diet and Multiple Low-Dose Streptozotocin
Induced Type 2 Diabetes Rat Model.” Experimental Diabetes Research 2008
(January): 704045. doi:10.1155/2008/704045.
Universitas Sumatera Utara