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Efek MAA tehadap Embrio Praimplantasi Mus musculus lektor

Majalah Sriwijaya, Volume 36, Nomor 1 April 2003 Hal 67-72

ISSN 0126-4680

Efek Asam Metoksiasetat (MAA) Terhadap Perkembangan Embrio Tahap
Praimplantasi Mencit (Mus musculus) Swiss Webster
The Effects of Methoxyacetid Acid On Developmental Preimplantation Stage
Embryos of Swiss Webster Mice (Mus musculus)
Riyanto*)

Abstract
The effects of methoxyacetic acid on preimplantation stage embryos of Swiss Webster
mice (Mus musculus) have been studied. Female mice were superovulated with 5 I.U. of
PMSG (Folligon) and 5 I.U. of hCG (Chorulon) and were mated with male mice overnight. A
veginal plug detected at the following morning was confirmed as day 0 of gestation. On
gestation day 2, mice were administered with MAA dose 2.5 mmol/kg bw by gevage. On
gestation day 3.5 mice were sacrificed for embryo collection. The result showed that MAA
could decrease significantly (p

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