ANINDARAMADHIANI 22010110110065 BAB8KTI
DAFTAR PUSTAKA
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dan
Kombinasi
Parasetamol+Kodein.
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Anestesiologi
Fakultas
Kedokteran Universitas Diponegoro. Semarang, 2000; 4-14
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Kadar Il-6 dan Intensitas Nyeri Pascabedah Laparotomi Ginekologi. Jurnal
Anestesiologi Indonesia Volume V. Nomor 2. 2013. Diakses tanggal: 29 Nov
2013
3. Soenarjo, Jatmiko H & dkk. Anestesiologi. Masalah nyeri. Semarang: Bagian
Anestesiologi dan Terapi Intensif Fakultas Kedokteran Undip/RSUP Dr.
Kariadi Semarang, 2013
-4. Wilmana, PF. Farmakologi dan terapi edisi 5. Jakarta: Balai Penerbit FKUI,
2007
5. Bedah info. Parasetamol mampukah mengatasi nyeri pasca operasi [internet].
2011.
Diakses
tanggal:
29
Nov
2013.
Available
from:
http://bedah.info/2011/03/parasetamol-mampukah-mengatasi-nyeri-pascaoperasi/
6. L Toms, et al. Single dose oral paracetamol (acetaminophen) for postoperative
pain in adults (Review). The Cochrane Library [internet]. 2012. Diakses
tanggal: 29 Nov 2013. Available from: http://www.thecochranelibrary.com
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vecuronium in cardiac surgical patients. Anesth Analg, 1988; 67: 161 – 5
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New York: Grune & Stratton Inc, 1979: 71 ‐ 110
9. Gwinnutt, CL. Anestesi Klinis. Catatan Kuliah (3 ed.). (D. Susanto, Trans.)
Jakarta: Penerbit Buku Kedokteran EGC, 2013; 89
10. Price, SA & Wilson, LM. Patofisiologi (6 ed.). Jakarta: Penerbit Buku
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12. Marsaban A ME, Bagianto H. Ilmu Pengetahuan Dasar Mekanisme Fisiologi
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13. Constanzo, LS. Essential Fisiologi Kedokteran (kelima ed.). Tangerang
Selatan: Binarupa Aksara. 2012; 119-121
14. Corwin, EJ. Buku Saku Patofisiologi (3rd revisi ed.). Jakarta: Penerbit Buku
Kedokteran EGC. 2009; 455
15. Gunawan, SG. Famakologi dan Terapi (5 ed.). Jakarta: Departemen
Farmakologi dan Terapeutik Fakultas Kedokteran Universitas Indonesia. 2011;
237-239
16. Nasution, YA. Penetapan Kadar Zat Aktif Parasetamol Dalam Obat Sediaan
Oral Dengan Metode Kromatografi Cair Kinerja Tinggi (KCKT). 2009.
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18. Duggan ST And Scott LJ. Intravenous Paracetamol(Acetaminophen).Drugs
2009;69:101-13
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21. Darmojo, RB. Ilmu Penyakit Dalam. Diagnosis Fisik dan Kardiologi.(Catatan
Kuliah). Semarang: Fakultas Kedokteran Universitas Diponegoro. 46-47
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abdominal hysterectomy. Pubmed: 2009. Diakses tanggal: 16 Juni 2014.
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Liver Functions and the Postoperative Analgesia in the Patients Underwent
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paracetamol – pethidin sebagai multimodal analgesia pada pasca bedah section
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Fakultas Kedokteran Universita Hasanudin Makasar. 2013. Diakses tanggal: 28
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Nov 2013.
LAMPIRAN
BIODATA MAHASISWA
Nama
:
Aninda Ramadhiani
NIM
:
22010110110065
Tempat/tanggal lahir :
Tegal/5 Maret 1993
Jenis Kelamin
:
Perempuan
Alamat
:
Tamansari Majapahit Grand Amarta A510 Smg
Nomor Telepon
:
081226412247
e-mail
:
anindara@ymail.com
Riwayat Pendidikan Formal
1. SD
:
SD Negeri 2 Brebes
Lulus tahun: 2004
2. SMP
:
SMP N 2 Brebes
Lulus tahun: 2007
3. SMA
:
SMA N 1 Brebes
Lulus tahun: 2010
4. FK UNDIP
:
Masuk tahun: 2010
JUDUL PENELITIAN
: Perubahan Hemodinamik Pada Pasien Post
Operative yang Diberi Paracetamol untuk
Menghilangkan Nyeri
INSTANSI PELAKSANA
: Fakultas Kedokteran Universitas Diponegoro
PENELITI
: Aninda Ramadhiani
Persetujuan Setelah Penjelasan
(INFORMED CONSENT)
Berikut ini naskah yang akan dibacakan pada Responden / Ibu Responden
Penelitian :
(a.l. berisi penjelasan apa yang akan dialami oleh responden mis : diambil
darah & diwawancarai)
Bapak/Ibu Yth :
Peneliti yang tersebut di atas adalah Mahasiswa Fakultas Kedokteran
Universitas Diponegoro yang bermaksud ingin menggunakan data rekam
medik
dalam
penelitian
ini
dengan
tujuan
mengetahui
perubahan
hemodinamik pada pasien post operative yang diberi parasetamol untuk
menghilangkan nyeri. Peneliti akan mengambil data identitas dan status
hemodinamik pasien. Peneliti menjamin kerahasiaan identitas dan informasi
yang diberikan. Informasi tersebut hanya digunakan untuk kepentingan
penelitian. Bapak/Ibu berhak menolak dan keluar dari penelitian sesuai dengan
keinginan.
Terima kasih atas kerjasama Bapak/Ibu/Sdr.
Setelah mendengar dan memahami penjelasan Penelitian, dengan ini saya
menyatakan
SETUJU / TIDAK SETUJU
Untuk ikut sebagai responden / sampel penelitian.
Semarang,………………
Saksi :
Nama Terang
:
Nama Terang :
Alamat
:
Alamat
:
Ethical Clearance
Surat ijin Penelitian
Form Anestesi
Umur
Case Summaries
Umur
Kelompok
Perlakuan
Kontrol
Total
N
20
20
40
Mean
44.15
44.40
44.28
Std. Deviation
8.993
9.676
9.221
Median
45.50
44.00
45.00
Minimum
24
28
24
Maximum
57
58
58
Tests of Normality
a
Umur
Kelompok
Perlakuan
Kontrol
Kolmogorov-Smirnov
Statistic
df
Sig.
.127
20
.200*
.184
20
.075
Statistic
.959
.927
*. This is a lower bound of the true significance.
a. Lilliefors Significance Correction
60
Umur
50
40
30
20
Perlakuan
Kontrol
Kelompok
Shapiro-Wilk
df
20
20
Sig.
.516
.137
T-Test
Group Statistics
Umur
Kelompok
Perlakuan
Kontrol
N
20
20
Mean
44.15
44.40
Std. Deviation
8.993
9.676
Std. Error
Mean
2.011
2.164
Independent Samples Test
Levene's Test for
Equality of Variances
t-test for Equality of
Means
Umur
Equal variances
Equal variances
assumed
not assumed
.602
.443
-.085
-.085
38
37.798
.933
.933
F
Sig.
t
df
Sig. (2-tailed)
Mean Difference
Std. Error Difference
95% Confidence Interval
of the Difference
Lower
Upper
-.250
-.250
2.954
2.954
-6.230
5.730
-6.231
5.731
Crosstabs
Jenis kelamin * Kelompok Crosstabulation
Jenis kelamin
Laki-laki
Perempuan
Total
Count
Expected Count
% within Kelompok
% of Total
Count
Expected Count
% within Kelompok
% of Total
Count
Expected Count
% within Kelompok
% of Total
Kelompok
Perlakuan
Kontrol
4
8
6.0
6.0
20.0%
40.0%
10.0%
20.0%
16
12
14.0
14.0
80.0%
60.0%
40.0%
30.0%
20
20
20.0
20.0
100.0%
100.0%
50.0%
50.0%
Total
12
12.0
30.0%
30.0%
28
28.0
70.0%
70.0%
40
40.0
100.0%
100.0%
Chi-Square Tests
Pearson Chi-Square
Continuity Correctiona
Likelihood Ratio
Fisher's Exact Test
Linear-by-Linear
Association
N of Valid Cases
Value
1.905b
1.071
1.933
1.857
df
1
1
1
1
Asymp. Sig.
(2-sided)
.168
.301
.164
Exact Sig.
(2-sided)
Exact Sig.
(1-sided)
.301
.150
.173
40
a. Computed only for a 2x2 table
b. 0 cells (.0%) have expected count less than 5. The minimum expected count is 6.
00.
Kelompok
Case Summaries
Kelompok
Perlakuan
Kontrol
Total
N
Mean
Std. Deviation
Median
Minimum
Maximum
N
Mean
Std. Deviation
Median
Minimum
Maximum
N
Mean
Std. Deviation
Median
Minimum
Maximum
Sistolik jam-1
20
139.95
23.502
134.50
105
176
20
136.20
23.574
132.00
100
171
40
138.07
23.312
132.00
100
176
Sistolik
jam-12
20
123.05
21.432
119.50
88
170
20
132.90
22.508
130.50
98
170
40
127.98
22.259
120.00
88
170
Tests of Normality
a
Sistolik jam-1
Sistolik jam-12
Kelompok
Perlakuan
Kontrol
Perlakuan
Kontrol
Kolmogorov-Smirnov
Statistic
df
Sig.
.164
20
.164
.139
20
.200*
.207
20
.025
.118
20
.200*
*. This is a lower bound of the true significance.
a. Lilliefors Significance Correction
Statistic
.916
.930
.932
.948
Shapiro-Wilk
df
20
20
20
20
Sig.
.082
.157
.168
.332
Sistolik jam-1
180
Sistolik jam-1
160
140
120
100
Perlakuan
Kontrol
Kelompok
Sistolik jam-12
180
Sistolik jam-12
160
140
120
100
80
Perlakuan
Kontrol
Kelompok
Perlakuan
T-Test
Paired Samples Statistics
Pair
1
Sistolik jam-1
Sistolik jam-12
Mean
139.95
123.05
N
20
20
Std. Deviation
23.502
21.432
Std. Error
Mean
5.255
4.792
Paired Samples Correlations
N
Pair
1
Sistolik jam-1 &
Sistolik jam-12
Correlation
20
.770
Sig.
.000
Paired Samples Test
Paired Differences
Mean
Std. Deviation
Std. Error Mean
95% Confidence Interval
of the Difference
t
df
Sig. (2-tailed)
Pair 1
Sistolik jam-1 Sistolik jam-12
16.900
15.376
3.438
Lower
Upper
9.704
24.096
4.916
19
.000
Kontrol
T-Test
Paired Samples Statistics
Pair
1
Sistolik jam-1
Sistolik jam-12
Mean
136.20
132.90
N
20
20
Std. Deviation
23.574
22.508
Std. Error
Mean
5.271
5.033
Paired Samples Correlations
N
Pair
1
Sistolik jam-1 &
Sistolik jam-12
Correlation
20
.995
Sig.
.000
Paired Samples Test
Paired Differences
Mean
Std. Deviation
Std. Error Mean
95% Confidence Interval
of the Difference
t
df
Sig. (2-tailed)
Pair 1
Sistolik jam-1 Sistolik jam-12
3.300
2.452
.548
Lower
Upper
2.153
4.447
6.020
19
.000
T-Test
Group Statistics
Sistolik jam-1
Kelompok
Perlakuan
Kontrol
N
20
20
Mean
139.95
136.20
Std. Deviation
23.502
23.574
Std. Error
Mean
5.255
5.271
Independent Samples Test
Levene's Test for
Equality of Variances
t-test for Equality of
Means
Sistolik jam-1
Equal variances
Equal variances
assumed
not assumed
.066
.798
.504
.504
38
38.000
.617
.617
F
Sig.
t
df
Sig. (2-tailed)
Mean Difference
Std. Error Difference
95% Confidence Interval
of the Difference
Lower
Upper
3.750
3.750
7.443
7.443
-11.319
18.819
-11.319
18.819
T-Test
Group Statistics
Sistolik jam-12
Kelompok
Perlakuan
Kontrol
N
20
20
Mean
123.05
132.90
Std. Deviation
21.432
22.508
Std. Error
Mean
4.792
5.033
Independent Samples Test
Levene's Test for
Equality of Variances
t-test for Equality of
Means
Sistolik jam-12
Equal variances
Equal variances
assumed
not assumed
.161
.690
-1.417
-1.417
38
37.909
.165
.165
F
Sig.
t
df
Sig. (2-tailed)
Mean Difference
Std. Error Difference
95% Confidence Interval
of the Difference
Lower
Upper
-9.850
-9.850
6.950
6.950
-23.919
4.219
-23.920
4.220
Kelompok
Case Summaries
Kelompok
Perlakuan
Kontrol
Total
Diastolik
jam-1
20
79.05
10.787
80.00
60
97
20
74.70
9.200
74.00
60
90
40
76.88
10.138
78.00
60
97
N
Mean
Std. Deviation
Median
Minimum
Maximum
N
Mean
Std. Deviation
Median
Minimum
Maximum
N
Mean
Std. Deviation
Median
Minimum
Maximum
Diastolik
jam-12
20
71.80
8.063
70.00
54
90
20
70.85
8.683
70.00
57
87
40
71.32
8.285
70.00
54
90
Tests of Normality
a
Diastolik jam-1
Diastolik jam-12
Kelompok
Perlakuan
Kontrol
Perlakuan
Kontrol
Kolmogorov-Smirnov
Statistic
df
Sig.
.145
20
.200*
.104
20
.200*
.188
20
.061
.117
20
.200*
*. This is a lower bound of the true significance.
a. Lilliefors Significance Correction
Statistic
.952
.961
.958
.959
Shapiro-Wilk
df
20
20
20
20
Sig.
.403
.567
.497
.525
Diastolik jam-1
100
Diastolik jam-1
90
80
70
60
Perlakuan
Kontrol
Kelompok
Diastolik jam-12
90
Diastolik jam-12
80
70
60
50
Perlakuan
Kontrol
Kelompok
Perlakuan
T-Test
Paired Samples Statistics
Pair
1
Diastolik jam-1
Diastolik jam-12
Mean
79.05
71.80
N
20
20
Std. Deviation
10.787
8.063
Std. Error
Mean
2.412
1.803
Paired Samples Correlations
N
Pair
1
Diastolik jam-1 &
Diastolik jam-12
Correlation
20
.659
Sig.
.002
Paired Samples Test
Paired Differences
Mean
Std. Deviation
Std. Error Mean
95% Confidence Interval
of the Difference
t
df
Sig. (2-tailed)
Pair 1
Diastolik jam-1 Diastolik jam-12
7.250
8.168
1.827
Lower
Upper
3.427
11.073
3.969
19
.001
Kontrol
T-Test
Paired Samples Statistics
Pair
1
Diastolik jam-1
Diastolik jam-12
Mean
74.70
70.85
N
20
20
Std. Deviation
9.200
8.683
Std. Error
Mean
2.057
1.942
Paired Samples Correlations
N
Pair
1
Diastolik jam-1 &
Diastolik jam-12
Correlation
20
.953
Sig.
.000
Paired Samples Test
Paired Differences
Mean
Std. Deviation
Std. Error Mean
95% Confidence Interval
of the Difference
t
df
Sig. (2-tailed)
Pair 1
Diastolik jam-1 Diastolik jam-12
3.850
2.796
.625
Lower
Upper
2.541
5.159
6.158
19
.000
T-Test
Group Statistics
Diastolik jam-1
Kelompok
Perlakuan
Kontrol
N
20
20
Mean
79.05
74.70
Std. Deviation
10.787
9.200
Std. Error
Mean
2.412
2.057
Independent Samples Test
Levene's Test for
Equality of Variances
t-test for Equality of
Means
Diastolik jam-1
Equal variances
Equal variances
assumed
not assumed
.435
.514
1.372
1.372
38
37.076
.178
.178
F
Sig.
t
df
Sig. (2-tailed)
Mean Difference
Std. Error Difference
95% Confidence Interval
of the Difference
Lower
Upper
4.350
4.350
3.170
3.170
-2.068
10.768
-2.073
10.773
T-Test
Group Statistics
Diastolik jam-12
Kelompok
Perlakuan
Kontrol
N
20
20
Mean
71.80
70.85
Std. Deviation
8.063
8.683
Std. Error
Mean
1.803
1.942
Independent Samples Test
Levene's Test for
Equality of Variances
t-test for Equality of
Means
Diastolik jam-12
Equal variances
Equal variances
assumed
not assumed
.241
.626
.359
.359
38
37.793
.722
.722
F
Sig.
t
df
Sig. (2-tailed)
Mean Difference
Std. Error Difference
95% Confidence Interval
of the Difference
Lower
Upper
.950
.950
2.650
2.650
-4.414
6.314
-4.415
6.315
Kelompok
Case Summaries
Kelompok
Perlakuan
Kontrol
Total
N
Mean
Std. Deviation
Median
Minimum
Maximum
N
Mean
Std. Deviation
Median
Minimum
Maximum
N
Mean
Std. Deviation
Median
Minimum
Maximum
Nadi jam-1
20
79.90
14.804
74.50
60
125
20
73.60
6.692
74.50
63
84
40
76.75
11.779
74.50
60
125
Nadi jam-12
20
75.40
14.259
72.00
58
120
20
72.00
6.798
73.00
61
82
40
73.70
11.159
72.50
58
120
Tests of Normality
a
Nadi jam-1
Nadi jam-12
Kelompok
Perlakuan
Kontrol
Perlakuan
Kontrol
Kolmogorov-Smirnov
Statistic
df
Sig.
.215
20
.016
.181
20
.087
.223
20
.010
.161
20
.184
a. Lilliefors Significance Correction
Statistic
.826
.925
.831
.922
Shapiro-Wilk
df
20
20
20
20
Sig.
.002
.124
.003
.110
Nadi jam-1
20
120
Nadi jam-1
2
100
80
60
Perlakuan
Kontrol
Kelompok
Nadi jam-12
120
20
Nadi jam-12
100
80
60
Perlakuan
Kontrol
Kelompok
Perlakuan
NPar Tests
Wilcoxon Signed Ranks Test
Ranks
N
Nadi jam-12 - Nadi jam-1
Negative Ranks
Positive Ranks
Ties
Total
a. Nadi jam-12 < Nadi jam-1
b. Nadi jam-12 > Nadi jam-1
c. Nadi jam-12 = Nadi jam-1
Test Statisticsb
Z
Asymp. Sig. (2-tailed)
Nadi jam-12
- Nadi jam-1
-3.998a
.000
a. Based on positive ranks.
b. Wilcoxon Signed Ranks Test
20a
0b
0c
20
Mean Rank
10.50
.00
Sum of Ranks
210.00
.00
Kontrol
T-Test
Paired Samples Statistics
Pair
1
Mean
73.60
72.00
Nadi jam-1
Nadi jam-12
N
Std. Deviation
6.692
6.798
20
20
Std. Error
Mean
1.496
1.520
Paired Samples Correlations
N
Pair
1
Nadi jam-1 &
Nadi jam-12
Correlation
20
.996
Sig.
.000
Paired Samples Test
Paired Differences
Mean
Std. Deviation
Std. Error Mean
95% Confidence Interval
of the Difference
t
df
Sig. (2-tailed)
Pair 1
Nadi jam-1 - Nadi jam-12
1.600
.598
.134
Lower
Upper
1.320
1.880
11.961
19
.000
NPar Tests
Mann-Whitney Test
Ranks
Nadi jam-1
Nadi jam-12
Kelompok
Perlakuan
Kontrol
Total
Perlakuan
Kontrol
Total
N
20
20
40
20
20
40
Mean Rank
22.70
18.30
Sum of Ranks
454.00
366.00
20.73
20.28
414.50
405.50
Test Statisticsb
Mann-Whitney U
Wilcoxon W
Z
Asymp. Sig. (2-tailed)
Exact Sig. [2*(1-tailed
Sig.)]
Nadi jam-1
156.000
366.000
-1.194
.232
a
.242
a. Not corrected for ties.
b. Grouping Variable: Kelompok
Nadi jam-12
195.500
405.500
-.122
.903
a
.904
Kelompok
Case Summaries
Kelompok
Perlakuan
Kontrol
Total
N
Mean
Std. Deviation
Median
Minimum
Maximum
N
Mean
Std. Deviation
Median
Minimum
Maximum
N
Mean
Std. Deviation
Median
Minimum
Maximum
Tekanan
nadi jam-1
20
42.45
9.536
42.81
24
59
20
44.40
6.421
45.13
30
54
40
43.43
8.085
43.69
24
59
Tekanan
nadi jam-12
20
40.59
8.544
38.41
27
54
20
45.92
6.835
46.76
30
57
40
43.25
8.100
42.09
27
57
Tests of Normality
a
Tekanan nadi jam-1
Tekanan nadi jam-12
Kelompok
Perlakuan
Kontrol
Perlakuan
Kontrol
Kolmogorov-Smirnov
Statistic
df
Sig.
.098
20
.200*
.154
20
.200*
.140
20
.200*
.124
20
.200*
*. This is a lower bound of the true significance.
a. Lilliefors Significance Correction
Statistic
.968
.958
.929
.946
Shapiro-Wilk
df
20
20
20
20
Sig.
.715
.506
.146
.311
Tekanan nadi jam-1
60
Tekanan nadi jam-1
50
40
30
20
Perlakuan
Kontrol
Kelompok
Tekanan nadi jam-12
60
Tekanan nadi jam-12
50
40
30
20
Perlakuan
Kontrol
Kelompok
Perlakuan
T-Test
Paired Samples Statistics
Pair
1
Tekanan nadi jam-1
Tekanan nadi jam-12
Mean
42.45
40.59
N
20
20
Std. Deviation
9.536
8.544
Std. Error
Mean
2.132
1.911
Paired Samples Correlations
N
Pair
1
Tekanan nadi jam-1 &
Tekanan nadi jam-12
Correlation
20
.632
Sig.
.003
Paired Samples Test
Paired Differences
Mean
Std. Deviation
Std. Error Mean
95% Confidence Interval
of the Difference
t
df
Sig. (2-tailed)
Pair 1
Tekanan nadi jam-1 Tekanan nadi jam-12
1.861
7.809
1.746
Lower
Upper
-1.794
5.516
1.066
19
.300
Kontrol
T-Test
Paired Samples Statistics
Pair
1
Tekanan nadi jam-1
Tekanan nadi jam-12
Mean
44.40
45.92
N
20
20
Std. Deviation
6.421
6.835
Std. Error
Mean
1.436
1.528
Paired Samples Correlations
N
Pair
1
Tekanan nadi jam-1 &
Tekanan nadi jam-12
Correlation
20
.980
Sig.
.000
Paired Samples Test
Paired Differences
Mean
Std. Deviation
Std. Error Mean
95% Confidence Interval
of the Difference
t
df
Sig. (2-tailed)
Pair 1
Tekanan nadi jam-1 Tekanan nadi jam-12
-1.515
1.373
.307
Lower
Upper
-2.158
-.872
-4.934
19
.000
T-Test
Group Statistics
Kelompok
Perlakuan
Kontrol
Tekanan nadi jam-1
N
20
20
Mean
42.45
44.40
Std. Deviation
9.536
6.421
Std. Error
Mean
2.132
1.436
Independent Samples Test
Levene's Test for
Equality of Variances
t-test for Equality of
Means
Tekanan nadi jam-1
Equal variances
Equal variances
assumed
not assumed
2.157
.150
-.760
-.760
38
33.291
.452
.453
F
Sig.
t
df
Sig. (2-tailed)
Mean Difference
Std. Error Difference
95% Confidence Interval
of the Difference
Lower
Upper
-1.954
-1.954
2.571
2.571
-7.158
3.250
-7.182
3.274
T-Test
Group Statistics
Tekanan nadi jam-12
Kelompok
Perlakuan
Kontrol
N
20
20
Mean
40.59
45.92
Std. Deviation
8.544
6.835
Std. Error
Mean
1.911
1.528
Independent Samples Test
Levene's Test for
Equality of Variances
t-test for Equality of
Means
Tekanan nadi jam-12
Equal variances
Equal variances
assumed
not assumed
1.987
.167
-2.178
-2.178
38
36.252
.036
.036
F
Sig.
t
df
Sig. (2-tailed)
Mean Difference
Std. Error Difference
95% Confidence Interval
of the Difference
Lower
Upper
-5.330
-5.330
2.447
2.447
-10.283
-.377
-10.291
-.369
Kelompok
Case Summaries
Kelompok
Perlakuan
Kontrol
Total
N
Mean
Std. Deviation
Median
Minimum
Maximum
N
Mean
Std. Deviation
Median
Minimum
Maximum
N
Mean
Std. Deviation
Median
Minimum
Maximum
MAP jam-1
20
99.35
12.306
102.50
75
121
20
95.20
13.084
93.67
73
115
40
97.27
12.712
99.00
73
121
MAP jam-12
20
89.38
11.296
90.00
65
117
20
91.63
12.129
91.67
71
110
40
90.51
11.625
90.17
65
117
Tests of Normality
a
MAP jam-1
MAP jam-12
Kelompok
Perlakuan
Kontrol
Perlakuan
Kontrol
Kolmogorov-Smirnov
Statistic
df
Sig.
.128
20
.200*
.142
20
.200*
.181
20
.086
.111
20
.200*
*. This is a lower bound of the true significance.
a. Lilliefors Significance Correction
Statistic
.962
.944
.954
.956
Shapiro-Wilk
df
20
20
20
20
Sig.
.590
.287
.439
.467
MAP jam-1
130
120
MAP jam-1
110
100
90
80
70
Perlakuan
Kontrol
Kelompok
MAP jam-12
120
11
110
MAP jam-12
100
90
80
70
16
60
Perlakuan
Kontrol
Kelompok
Perlakuan
T-Test
Paired Samples Statistics
Pair
1
MAP jam-1
MAP jam-12
Mean
99.35
89.38
N
20
20
Std. Deviation
12.306
11.296
Std. Error
Mean
2.752
2.526
Paired Samples Correlations
N
Pair 1
MAP jam-1 & MAP jam-12
20
Correlation
.745
Sig.
.000
Paired Samples Test
Paired Differences
Mean
Std. Deviation
Std. Error Mean
95% Confidence Interval
of the Difference
t
df
Sig. (2-tailed)
Pair 1
MAP jam-1 - MAP jam-12
9.968
8.479
1.896
Lower
Upper
5.999
13.936
5.257
19
.000
Kontrol
T-Test
Paired Samples Statistics
Pair
1
MAP jam-1
MAP jam-12
Mean
95.20
91.63
N
20
20
Std. Deviation
13.084
12.129
Std. Error
Mean
2.926
2.712
Paired Samples Correlations
N
Pair 1
MAP jam-1 & MAP jam-12
20
Correlation
.982
Sig.
.000
Paired Samples Test
Paired Differences
Mean
Std. Deviation
Std. Error Mean
95% Confidence Interval
of the Difference
t
df
Sig. (2-tailed)
Pair 1
MAP jam-1 - MAP jam-12
3.567
2.576
.576
Lower
Upper
2.361
4.773
6.192
19
.000
T-Test
Group Statistics
MAP jam-1
Kelompok
Perlakuan
Kontrol
N
20
20
Mean
99.35
95.20
Std. Error
Mean
2.752
2.926
Std. Deviation
12.306
13.084
Independent Samples Test
Levene's Test for
Equality of Variances
t-test for Equality of
Means
MAP jam-1
Equal variances
Equal variances
assumed
not assumed
.400
.531
1.033
1.033
38
37.858
.308
.308
F
Sig.
t
df
Sig. (2-tailed)
Mean Difference
Std. Error Difference
95% Confidence Interval
of the Difference
Lower
Upper
4.149
4.149
4.016
4.016
-3.982
12.280
-3.983
12.281
T-Test
Group Statistics
MAP jam-12
Kelompok
Perlakuan
Kontrol
N
20
20
Mean
89.38
91.63
Std. Deviation
11.296
12.129
Std. Error
Mean
2.526
2.712
Independent Samples Test
Levene's Test for
Equality of Variances
t-test for Equality of
Means
MAP jam-12
Equal variances
Equal variances
assumed
not assumed
.876
.355
-.608
-.608
38
37.809
.547
.547
F
Sig.
t
df
Sig. (2-tailed)
Mean Difference
Std. Error Difference
95% Confidence Interval
of the Difference
Lower
Upper
-2.252
-2.252
3.706
3.706
-9.754
5.251
-9.755
5.252
Dokumentasi
1. Medisono, W. Nyeri Pasca Herniorafi: Analgesi antara Meperidin, Parasetamol
dan
Kombinasi
Parasetamol+Kodein.
Bagian
Anestesiologi
Fakultas
Kedokteran Universitas Diponegoro. Semarang, 2000; 4-14
2. Haerudin H, Ahmad MR. Penelitian Pengaruh Pemberian Parecoxib Terhadap
Kadar Il-6 dan Intensitas Nyeri Pascabedah Laparotomi Ginekologi. Jurnal
Anestesiologi Indonesia Volume V. Nomor 2. 2013. Diakses tanggal: 29 Nov
2013
3. Soenarjo, Jatmiko H & dkk. Anestesiologi. Masalah nyeri. Semarang: Bagian
Anestesiologi dan Terapi Intensif Fakultas Kedokteran Undip/RSUP Dr.
Kariadi Semarang, 2013
-4. Wilmana, PF. Farmakologi dan terapi edisi 5. Jakarta: Balai Penerbit FKUI,
2007
5. Bedah info. Parasetamol mampukah mengatasi nyeri pasca operasi [internet].
2011.
Diakses
tanggal:
29
Nov
2013.
Available
from:
http://bedah.info/2011/03/parasetamol-mampukah-mengatasi-nyeri-pascaoperasi/
6. L Toms, et al. Single dose oral paracetamol (acetaminophen) for postoperative
pain in adults (Review). The Cochrane Library [internet]. 2012. Diakses
tanggal: 29 Nov 2013. Available from: http://www.thecochranelibrary.com
7. Gallo JA, Cork RC, Puchi P. Comparison of effects of atracurium and
vecuronium in cardiac surgical patients. Anesth Analg, 1988; 67: 161 – 5
8. Kaplan JA. Hemodynamic monitoring. In: Kaplan JA, ed. Cardiac anesthesia.
New York: Grune & Stratton Inc, 1979: 71 ‐ 110
9. Gwinnutt, CL. Anestesi Klinis. Catatan Kuliah (3 ed.). (D. Susanto, Trans.)
Jakarta: Penerbit Buku Kedokteran EGC, 2013; 89
10. Price, SA & Wilson, LM. Patofisiologi (6 ed.). Jakarta: Penerbit Buku
Kedokteran EGC, 2006
11. Morgan , E. Clinical Anestesiology (4 ed.). New York: Lang, 2006; 367
12. Marsaban A ME, Bagianto H. Ilmu Pengetahuan Dasar Mekanisme Fisiologi
Nyeri In: S C ed. Jakarta: Perhimpunan Dokter Spesialis Anestesiologi dan
Reanimasi Indonesia, 2009
13. Constanzo, LS. Essential Fisiologi Kedokteran (kelima ed.). Tangerang
Selatan: Binarupa Aksara. 2012; 119-121
14. Corwin, EJ. Buku Saku Patofisiologi (3rd revisi ed.). Jakarta: Penerbit Buku
Kedokteran EGC. 2009; 455
15. Gunawan, SG. Famakologi dan Terapi (5 ed.). Jakarta: Departemen
Farmakologi dan Terapeutik Fakultas Kedokteran Universitas Indonesia. 2011;
237-239
16. Nasution, YA. Penetapan Kadar Zat Aktif Parasetamol Dalam Obat Sediaan
Oral Dengan Metode Kromatografi Cair Kinerja Tinggi (KCKT). 2009.
Diakses tanggal: 29 Nov 2013
17. Tan I. Farmakologi dan Terapi.Jakarta: Balai Penerbit FKUI, 2007.
18. Duggan ST And Scott LJ. Intravenous Paracetamol(Acetaminophen).Drugs
2009;69:101-13
19. Guyton, Hall. Buku Ajar Fisiologi Kedokteran. Jakarta: EGC Medical
Publisher. 2008: 180
20. Dahlan MS. Statistik untuk Kedokteran dan Kesehatan. Jakarta: Salemba
Medika. 2011
21. Darmojo, RB. Ilmu Penyakit Dalam. Diagnosis Fisik dan Kardiologi.(Catatan
Kuliah). Semarang: Fakultas Kedokteran Universitas Diponegoro. 46-47
22. Arici S, et al. Preemptive Analgesic effects of intravenous paracetamol in total
abdominal hysterectomy. Pubmed: 2009. Diakses tanggal: 16 Juni 2014.
23. Harun A, et al. The Effect of IV Paracetamol on the Hemodynamic Indices,
Liver Functions and the Postoperative Analgesia in the Patients Underwent
Major Orthopaedic Surgery. Erciyes Medical Journal: 2008. Diakses tanggal:
16 Juni 2014.
24. Faisal dkk, Perbandingan efek kombinasi paracetamol – ketamin dengan
paracetamol – pethidin sebagai multimodal analgesia pada pasca bedah section
caesaria. Bagian Anaestesiolog, Perawatan Intensif dan Manajemen Nyeri
Fakultas Kedokteran Universita Hasanudin Makasar. 2013. Diakses tanggal: 28
Nov 2013.
25. A. Zeidan et al, Median effective dose (ED50) of paracetamol and morphine
for postoperative pain. British Journal of Anaesthesia Page 1 of 6. 2013.
Diakses tanggal: 28 Nov 2013.
26. Ong, Cliff K. S et al, Combining Paracetamol (Acetaminophen) with Nonsteroidal
Antiinflammatory Drugs. Anesth Analg 110:1170–9. 2010. Diakses tanggal: 28
Nov 2013.
LAMPIRAN
BIODATA MAHASISWA
Nama
:
Aninda Ramadhiani
NIM
:
22010110110065
Tempat/tanggal lahir :
Tegal/5 Maret 1993
Jenis Kelamin
:
Perempuan
Alamat
:
Tamansari Majapahit Grand Amarta A510 Smg
Nomor Telepon
:
081226412247
:
anindara@ymail.com
Riwayat Pendidikan Formal
1. SD
:
SD Negeri 2 Brebes
Lulus tahun: 2004
2. SMP
:
SMP N 2 Brebes
Lulus tahun: 2007
3. SMA
:
SMA N 1 Brebes
Lulus tahun: 2010
4. FK UNDIP
:
Masuk tahun: 2010
JUDUL PENELITIAN
: Perubahan Hemodinamik Pada Pasien Post
Operative yang Diberi Paracetamol untuk
Menghilangkan Nyeri
INSTANSI PELAKSANA
: Fakultas Kedokteran Universitas Diponegoro
PENELITI
: Aninda Ramadhiani
Persetujuan Setelah Penjelasan
(INFORMED CONSENT)
Berikut ini naskah yang akan dibacakan pada Responden / Ibu Responden
Penelitian :
(a.l. berisi penjelasan apa yang akan dialami oleh responden mis : diambil
darah & diwawancarai)
Bapak/Ibu Yth :
Peneliti yang tersebut di atas adalah Mahasiswa Fakultas Kedokteran
Universitas Diponegoro yang bermaksud ingin menggunakan data rekam
medik
dalam
penelitian
ini
dengan
tujuan
mengetahui
perubahan
hemodinamik pada pasien post operative yang diberi parasetamol untuk
menghilangkan nyeri. Peneliti akan mengambil data identitas dan status
hemodinamik pasien. Peneliti menjamin kerahasiaan identitas dan informasi
yang diberikan. Informasi tersebut hanya digunakan untuk kepentingan
penelitian. Bapak/Ibu berhak menolak dan keluar dari penelitian sesuai dengan
keinginan.
Terima kasih atas kerjasama Bapak/Ibu/Sdr.
Setelah mendengar dan memahami penjelasan Penelitian, dengan ini saya
menyatakan
SETUJU / TIDAK SETUJU
Untuk ikut sebagai responden / sampel penelitian.
Semarang,………………
Saksi :
Nama Terang
:
Nama Terang :
Alamat
:
Alamat
:
Ethical Clearance
Surat ijin Penelitian
Form Anestesi
Umur
Case Summaries
Umur
Kelompok
Perlakuan
Kontrol
Total
N
20
20
40
Mean
44.15
44.40
44.28
Std. Deviation
8.993
9.676
9.221
Median
45.50
44.00
45.00
Minimum
24
28
24
Maximum
57
58
58
Tests of Normality
a
Umur
Kelompok
Perlakuan
Kontrol
Kolmogorov-Smirnov
Statistic
df
Sig.
.127
20
.200*
.184
20
.075
Statistic
.959
.927
*. This is a lower bound of the true significance.
a. Lilliefors Significance Correction
60
Umur
50
40
30
20
Perlakuan
Kontrol
Kelompok
Shapiro-Wilk
df
20
20
Sig.
.516
.137
T-Test
Group Statistics
Umur
Kelompok
Perlakuan
Kontrol
N
20
20
Mean
44.15
44.40
Std. Deviation
8.993
9.676
Std. Error
Mean
2.011
2.164
Independent Samples Test
Levene's Test for
Equality of Variances
t-test for Equality of
Means
Umur
Equal variances
Equal variances
assumed
not assumed
.602
.443
-.085
-.085
38
37.798
.933
.933
F
Sig.
t
df
Sig. (2-tailed)
Mean Difference
Std. Error Difference
95% Confidence Interval
of the Difference
Lower
Upper
-.250
-.250
2.954
2.954
-6.230
5.730
-6.231
5.731
Crosstabs
Jenis kelamin * Kelompok Crosstabulation
Jenis kelamin
Laki-laki
Perempuan
Total
Count
Expected Count
% within Kelompok
% of Total
Count
Expected Count
% within Kelompok
% of Total
Count
Expected Count
% within Kelompok
% of Total
Kelompok
Perlakuan
Kontrol
4
8
6.0
6.0
20.0%
40.0%
10.0%
20.0%
16
12
14.0
14.0
80.0%
60.0%
40.0%
30.0%
20
20
20.0
20.0
100.0%
100.0%
50.0%
50.0%
Total
12
12.0
30.0%
30.0%
28
28.0
70.0%
70.0%
40
40.0
100.0%
100.0%
Chi-Square Tests
Pearson Chi-Square
Continuity Correctiona
Likelihood Ratio
Fisher's Exact Test
Linear-by-Linear
Association
N of Valid Cases
Value
1.905b
1.071
1.933
1.857
df
1
1
1
1
Asymp. Sig.
(2-sided)
.168
.301
.164
Exact Sig.
(2-sided)
Exact Sig.
(1-sided)
.301
.150
.173
40
a. Computed only for a 2x2 table
b. 0 cells (.0%) have expected count less than 5. The minimum expected count is 6.
00.
Kelompok
Case Summaries
Kelompok
Perlakuan
Kontrol
Total
N
Mean
Std. Deviation
Median
Minimum
Maximum
N
Mean
Std. Deviation
Median
Minimum
Maximum
N
Mean
Std. Deviation
Median
Minimum
Maximum
Sistolik jam-1
20
139.95
23.502
134.50
105
176
20
136.20
23.574
132.00
100
171
40
138.07
23.312
132.00
100
176
Sistolik
jam-12
20
123.05
21.432
119.50
88
170
20
132.90
22.508
130.50
98
170
40
127.98
22.259
120.00
88
170
Tests of Normality
a
Sistolik jam-1
Sistolik jam-12
Kelompok
Perlakuan
Kontrol
Perlakuan
Kontrol
Kolmogorov-Smirnov
Statistic
df
Sig.
.164
20
.164
.139
20
.200*
.207
20
.025
.118
20
.200*
*. This is a lower bound of the true significance.
a. Lilliefors Significance Correction
Statistic
.916
.930
.932
.948
Shapiro-Wilk
df
20
20
20
20
Sig.
.082
.157
.168
.332
Sistolik jam-1
180
Sistolik jam-1
160
140
120
100
Perlakuan
Kontrol
Kelompok
Sistolik jam-12
180
Sistolik jam-12
160
140
120
100
80
Perlakuan
Kontrol
Kelompok
Perlakuan
T-Test
Paired Samples Statistics
Pair
1
Sistolik jam-1
Sistolik jam-12
Mean
139.95
123.05
N
20
20
Std. Deviation
23.502
21.432
Std. Error
Mean
5.255
4.792
Paired Samples Correlations
N
Pair
1
Sistolik jam-1 &
Sistolik jam-12
Correlation
20
.770
Sig.
.000
Paired Samples Test
Paired Differences
Mean
Std. Deviation
Std. Error Mean
95% Confidence Interval
of the Difference
t
df
Sig. (2-tailed)
Pair 1
Sistolik jam-1 Sistolik jam-12
16.900
15.376
3.438
Lower
Upper
9.704
24.096
4.916
19
.000
Kontrol
T-Test
Paired Samples Statistics
Pair
1
Sistolik jam-1
Sistolik jam-12
Mean
136.20
132.90
N
20
20
Std. Deviation
23.574
22.508
Std. Error
Mean
5.271
5.033
Paired Samples Correlations
N
Pair
1
Sistolik jam-1 &
Sistolik jam-12
Correlation
20
.995
Sig.
.000
Paired Samples Test
Paired Differences
Mean
Std. Deviation
Std. Error Mean
95% Confidence Interval
of the Difference
t
df
Sig. (2-tailed)
Pair 1
Sistolik jam-1 Sistolik jam-12
3.300
2.452
.548
Lower
Upper
2.153
4.447
6.020
19
.000
T-Test
Group Statistics
Sistolik jam-1
Kelompok
Perlakuan
Kontrol
N
20
20
Mean
139.95
136.20
Std. Deviation
23.502
23.574
Std. Error
Mean
5.255
5.271
Independent Samples Test
Levene's Test for
Equality of Variances
t-test for Equality of
Means
Sistolik jam-1
Equal variances
Equal variances
assumed
not assumed
.066
.798
.504
.504
38
38.000
.617
.617
F
Sig.
t
df
Sig. (2-tailed)
Mean Difference
Std. Error Difference
95% Confidence Interval
of the Difference
Lower
Upper
3.750
3.750
7.443
7.443
-11.319
18.819
-11.319
18.819
T-Test
Group Statistics
Sistolik jam-12
Kelompok
Perlakuan
Kontrol
N
20
20
Mean
123.05
132.90
Std. Deviation
21.432
22.508
Std. Error
Mean
4.792
5.033
Independent Samples Test
Levene's Test for
Equality of Variances
t-test for Equality of
Means
Sistolik jam-12
Equal variances
Equal variances
assumed
not assumed
.161
.690
-1.417
-1.417
38
37.909
.165
.165
F
Sig.
t
df
Sig. (2-tailed)
Mean Difference
Std. Error Difference
95% Confidence Interval
of the Difference
Lower
Upper
-9.850
-9.850
6.950
6.950
-23.919
4.219
-23.920
4.220
Kelompok
Case Summaries
Kelompok
Perlakuan
Kontrol
Total
Diastolik
jam-1
20
79.05
10.787
80.00
60
97
20
74.70
9.200
74.00
60
90
40
76.88
10.138
78.00
60
97
N
Mean
Std. Deviation
Median
Minimum
Maximum
N
Mean
Std. Deviation
Median
Minimum
Maximum
N
Mean
Std. Deviation
Median
Minimum
Maximum
Diastolik
jam-12
20
71.80
8.063
70.00
54
90
20
70.85
8.683
70.00
57
87
40
71.32
8.285
70.00
54
90
Tests of Normality
a
Diastolik jam-1
Diastolik jam-12
Kelompok
Perlakuan
Kontrol
Perlakuan
Kontrol
Kolmogorov-Smirnov
Statistic
df
Sig.
.145
20
.200*
.104
20
.200*
.188
20
.061
.117
20
.200*
*. This is a lower bound of the true significance.
a. Lilliefors Significance Correction
Statistic
.952
.961
.958
.959
Shapiro-Wilk
df
20
20
20
20
Sig.
.403
.567
.497
.525
Diastolik jam-1
100
Diastolik jam-1
90
80
70
60
Perlakuan
Kontrol
Kelompok
Diastolik jam-12
90
Diastolik jam-12
80
70
60
50
Perlakuan
Kontrol
Kelompok
Perlakuan
T-Test
Paired Samples Statistics
Pair
1
Diastolik jam-1
Diastolik jam-12
Mean
79.05
71.80
N
20
20
Std. Deviation
10.787
8.063
Std. Error
Mean
2.412
1.803
Paired Samples Correlations
N
Pair
1
Diastolik jam-1 &
Diastolik jam-12
Correlation
20
.659
Sig.
.002
Paired Samples Test
Paired Differences
Mean
Std. Deviation
Std. Error Mean
95% Confidence Interval
of the Difference
t
df
Sig. (2-tailed)
Pair 1
Diastolik jam-1 Diastolik jam-12
7.250
8.168
1.827
Lower
Upper
3.427
11.073
3.969
19
.001
Kontrol
T-Test
Paired Samples Statistics
Pair
1
Diastolik jam-1
Diastolik jam-12
Mean
74.70
70.85
N
20
20
Std. Deviation
9.200
8.683
Std. Error
Mean
2.057
1.942
Paired Samples Correlations
N
Pair
1
Diastolik jam-1 &
Diastolik jam-12
Correlation
20
.953
Sig.
.000
Paired Samples Test
Paired Differences
Mean
Std. Deviation
Std. Error Mean
95% Confidence Interval
of the Difference
t
df
Sig. (2-tailed)
Pair 1
Diastolik jam-1 Diastolik jam-12
3.850
2.796
.625
Lower
Upper
2.541
5.159
6.158
19
.000
T-Test
Group Statistics
Diastolik jam-1
Kelompok
Perlakuan
Kontrol
N
20
20
Mean
79.05
74.70
Std. Deviation
10.787
9.200
Std. Error
Mean
2.412
2.057
Independent Samples Test
Levene's Test for
Equality of Variances
t-test for Equality of
Means
Diastolik jam-1
Equal variances
Equal variances
assumed
not assumed
.435
.514
1.372
1.372
38
37.076
.178
.178
F
Sig.
t
df
Sig. (2-tailed)
Mean Difference
Std. Error Difference
95% Confidence Interval
of the Difference
Lower
Upper
4.350
4.350
3.170
3.170
-2.068
10.768
-2.073
10.773
T-Test
Group Statistics
Diastolik jam-12
Kelompok
Perlakuan
Kontrol
N
20
20
Mean
71.80
70.85
Std. Deviation
8.063
8.683
Std. Error
Mean
1.803
1.942
Independent Samples Test
Levene's Test for
Equality of Variances
t-test for Equality of
Means
Diastolik jam-12
Equal variances
Equal variances
assumed
not assumed
.241
.626
.359
.359
38
37.793
.722
.722
F
Sig.
t
df
Sig. (2-tailed)
Mean Difference
Std. Error Difference
95% Confidence Interval
of the Difference
Lower
Upper
.950
.950
2.650
2.650
-4.414
6.314
-4.415
6.315
Kelompok
Case Summaries
Kelompok
Perlakuan
Kontrol
Total
N
Mean
Std. Deviation
Median
Minimum
Maximum
N
Mean
Std. Deviation
Median
Minimum
Maximum
N
Mean
Std. Deviation
Median
Minimum
Maximum
Nadi jam-1
20
79.90
14.804
74.50
60
125
20
73.60
6.692
74.50
63
84
40
76.75
11.779
74.50
60
125
Nadi jam-12
20
75.40
14.259
72.00
58
120
20
72.00
6.798
73.00
61
82
40
73.70
11.159
72.50
58
120
Tests of Normality
a
Nadi jam-1
Nadi jam-12
Kelompok
Perlakuan
Kontrol
Perlakuan
Kontrol
Kolmogorov-Smirnov
Statistic
df
Sig.
.215
20
.016
.181
20
.087
.223
20
.010
.161
20
.184
a. Lilliefors Significance Correction
Statistic
.826
.925
.831
.922
Shapiro-Wilk
df
20
20
20
20
Sig.
.002
.124
.003
.110
Nadi jam-1
20
120
Nadi jam-1
2
100
80
60
Perlakuan
Kontrol
Kelompok
Nadi jam-12
120
20
Nadi jam-12
100
80
60
Perlakuan
Kontrol
Kelompok
Perlakuan
NPar Tests
Wilcoxon Signed Ranks Test
Ranks
N
Nadi jam-12 - Nadi jam-1
Negative Ranks
Positive Ranks
Ties
Total
a. Nadi jam-12 < Nadi jam-1
b. Nadi jam-12 > Nadi jam-1
c. Nadi jam-12 = Nadi jam-1
Test Statisticsb
Z
Asymp. Sig. (2-tailed)
Nadi jam-12
- Nadi jam-1
-3.998a
.000
a. Based on positive ranks.
b. Wilcoxon Signed Ranks Test
20a
0b
0c
20
Mean Rank
10.50
.00
Sum of Ranks
210.00
.00
Kontrol
T-Test
Paired Samples Statistics
Pair
1
Mean
73.60
72.00
Nadi jam-1
Nadi jam-12
N
Std. Deviation
6.692
6.798
20
20
Std. Error
Mean
1.496
1.520
Paired Samples Correlations
N
Pair
1
Nadi jam-1 &
Nadi jam-12
Correlation
20
.996
Sig.
.000
Paired Samples Test
Paired Differences
Mean
Std. Deviation
Std. Error Mean
95% Confidence Interval
of the Difference
t
df
Sig. (2-tailed)
Pair 1
Nadi jam-1 - Nadi jam-12
1.600
.598
.134
Lower
Upper
1.320
1.880
11.961
19
.000
NPar Tests
Mann-Whitney Test
Ranks
Nadi jam-1
Nadi jam-12
Kelompok
Perlakuan
Kontrol
Total
Perlakuan
Kontrol
Total
N
20
20
40
20
20
40
Mean Rank
22.70
18.30
Sum of Ranks
454.00
366.00
20.73
20.28
414.50
405.50
Test Statisticsb
Mann-Whitney U
Wilcoxon W
Z
Asymp. Sig. (2-tailed)
Exact Sig. [2*(1-tailed
Sig.)]
Nadi jam-1
156.000
366.000
-1.194
.232
a
.242
a. Not corrected for ties.
b. Grouping Variable: Kelompok
Nadi jam-12
195.500
405.500
-.122
.903
a
.904
Kelompok
Case Summaries
Kelompok
Perlakuan
Kontrol
Total
N
Mean
Std. Deviation
Median
Minimum
Maximum
N
Mean
Std. Deviation
Median
Minimum
Maximum
N
Mean
Std. Deviation
Median
Minimum
Maximum
Tekanan
nadi jam-1
20
42.45
9.536
42.81
24
59
20
44.40
6.421
45.13
30
54
40
43.43
8.085
43.69
24
59
Tekanan
nadi jam-12
20
40.59
8.544
38.41
27
54
20
45.92
6.835
46.76
30
57
40
43.25
8.100
42.09
27
57
Tests of Normality
a
Tekanan nadi jam-1
Tekanan nadi jam-12
Kelompok
Perlakuan
Kontrol
Perlakuan
Kontrol
Kolmogorov-Smirnov
Statistic
df
Sig.
.098
20
.200*
.154
20
.200*
.140
20
.200*
.124
20
.200*
*. This is a lower bound of the true significance.
a. Lilliefors Significance Correction
Statistic
.968
.958
.929
.946
Shapiro-Wilk
df
20
20
20
20
Sig.
.715
.506
.146
.311
Tekanan nadi jam-1
60
Tekanan nadi jam-1
50
40
30
20
Perlakuan
Kontrol
Kelompok
Tekanan nadi jam-12
60
Tekanan nadi jam-12
50
40
30
20
Perlakuan
Kontrol
Kelompok
Perlakuan
T-Test
Paired Samples Statistics
Pair
1
Tekanan nadi jam-1
Tekanan nadi jam-12
Mean
42.45
40.59
N
20
20
Std. Deviation
9.536
8.544
Std. Error
Mean
2.132
1.911
Paired Samples Correlations
N
Pair
1
Tekanan nadi jam-1 &
Tekanan nadi jam-12
Correlation
20
.632
Sig.
.003
Paired Samples Test
Paired Differences
Mean
Std. Deviation
Std. Error Mean
95% Confidence Interval
of the Difference
t
df
Sig. (2-tailed)
Pair 1
Tekanan nadi jam-1 Tekanan nadi jam-12
1.861
7.809
1.746
Lower
Upper
-1.794
5.516
1.066
19
.300
Kontrol
T-Test
Paired Samples Statistics
Pair
1
Tekanan nadi jam-1
Tekanan nadi jam-12
Mean
44.40
45.92
N
20
20
Std. Deviation
6.421
6.835
Std. Error
Mean
1.436
1.528
Paired Samples Correlations
N
Pair
1
Tekanan nadi jam-1 &
Tekanan nadi jam-12
Correlation
20
.980
Sig.
.000
Paired Samples Test
Paired Differences
Mean
Std. Deviation
Std. Error Mean
95% Confidence Interval
of the Difference
t
df
Sig. (2-tailed)
Pair 1
Tekanan nadi jam-1 Tekanan nadi jam-12
-1.515
1.373
.307
Lower
Upper
-2.158
-.872
-4.934
19
.000
T-Test
Group Statistics
Kelompok
Perlakuan
Kontrol
Tekanan nadi jam-1
N
20
20
Mean
42.45
44.40
Std. Deviation
9.536
6.421
Std. Error
Mean
2.132
1.436
Independent Samples Test
Levene's Test for
Equality of Variances
t-test for Equality of
Means
Tekanan nadi jam-1
Equal variances
Equal variances
assumed
not assumed
2.157
.150
-.760
-.760
38
33.291
.452
.453
F
Sig.
t
df
Sig. (2-tailed)
Mean Difference
Std. Error Difference
95% Confidence Interval
of the Difference
Lower
Upper
-1.954
-1.954
2.571
2.571
-7.158
3.250
-7.182
3.274
T-Test
Group Statistics
Tekanan nadi jam-12
Kelompok
Perlakuan
Kontrol
N
20
20
Mean
40.59
45.92
Std. Deviation
8.544
6.835
Std. Error
Mean
1.911
1.528
Independent Samples Test
Levene's Test for
Equality of Variances
t-test for Equality of
Means
Tekanan nadi jam-12
Equal variances
Equal variances
assumed
not assumed
1.987
.167
-2.178
-2.178
38
36.252
.036
.036
F
Sig.
t
df
Sig. (2-tailed)
Mean Difference
Std. Error Difference
95% Confidence Interval
of the Difference
Lower
Upper
-5.330
-5.330
2.447
2.447
-10.283
-.377
-10.291
-.369
Kelompok
Case Summaries
Kelompok
Perlakuan
Kontrol
Total
N
Mean
Std. Deviation
Median
Minimum
Maximum
N
Mean
Std. Deviation
Median
Minimum
Maximum
N
Mean
Std. Deviation
Median
Minimum
Maximum
MAP jam-1
20
99.35
12.306
102.50
75
121
20
95.20
13.084
93.67
73
115
40
97.27
12.712
99.00
73
121
MAP jam-12
20
89.38
11.296
90.00
65
117
20
91.63
12.129
91.67
71
110
40
90.51
11.625
90.17
65
117
Tests of Normality
a
MAP jam-1
MAP jam-12
Kelompok
Perlakuan
Kontrol
Perlakuan
Kontrol
Kolmogorov-Smirnov
Statistic
df
Sig.
.128
20
.200*
.142
20
.200*
.181
20
.086
.111
20
.200*
*. This is a lower bound of the true significance.
a. Lilliefors Significance Correction
Statistic
.962
.944
.954
.956
Shapiro-Wilk
df
20
20
20
20
Sig.
.590
.287
.439
.467
MAP jam-1
130
120
MAP jam-1
110
100
90
80
70
Perlakuan
Kontrol
Kelompok
MAP jam-12
120
11
110
MAP jam-12
100
90
80
70
16
60
Perlakuan
Kontrol
Kelompok
Perlakuan
T-Test
Paired Samples Statistics
Pair
1
MAP jam-1
MAP jam-12
Mean
99.35
89.38
N
20
20
Std. Deviation
12.306
11.296
Std. Error
Mean
2.752
2.526
Paired Samples Correlations
N
Pair 1
MAP jam-1 & MAP jam-12
20
Correlation
.745
Sig.
.000
Paired Samples Test
Paired Differences
Mean
Std. Deviation
Std. Error Mean
95% Confidence Interval
of the Difference
t
df
Sig. (2-tailed)
Pair 1
MAP jam-1 - MAP jam-12
9.968
8.479
1.896
Lower
Upper
5.999
13.936
5.257
19
.000
Kontrol
T-Test
Paired Samples Statistics
Pair
1
MAP jam-1
MAP jam-12
Mean
95.20
91.63
N
20
20
Std. Deviation
13.084
12.129
Std. Error
Mean
2.926
2.712
Paired Samples Correlations
N
Pair 1
MAP jam-1 & MAP jam-12
20
Correlation
.982
Sig.
.000
Paired Samples Test
Paired Differences
Mean
Std. Deviation
Std. Error Mean
95% Confidence Interval
of the Difference
t
df
Sig. (2-tailed)
Pair 1
MAP jam-1 - MAP jam-12
3.567
2.576
.576
Lower
Upper
2.361
4.773
6.192
19
.000
T-Test
Group Statistics
MAP jam-1
Kelompok
Perlakuan
Kontrol
N
20
20
Mean
99.35
95.20
Std. Error
Mean
2.752
2.926
Std. Deviation
12.306
13.084
Independent Samples Test
Levene's Test for
Equality of Variances
t-test for Equality of
Means
MAP jam-1
Equal variances
Equal variances
assumed
not assumed
.400
.531
1.033
1.033
38
37.858
.308
.308
F
Sig.
t
df
Sig. (2-tailed)
Mean Difference
Std. Error Difference
95% Confidence Interval
of the Difference
Lower
Upper
4.149
4.149
4.016
4.016
-3.982
12.280
-3.983
12.281
T-Test
Group Statistics
MAP jam-12
Kelompok
Perlakuan
Kontrol
N
20
20
Mean
89.38
91.63
Std. Deviation
11.296
12.129
Std. Error
Mean
2.526
2.712
Independent Samples Test
Levene's Test for
Equality of Variances
t-test for Equality of
Means
MAP jam-12
Equal variances
Equal variances
assumed
not assumed
.876
.355
-.608
-.608
38
37.809
.547
.547
F
Sig.
t
df
Sig. (2-tailed)
Mean Difference
Std. Error Difference
95% Confidence Interval
of the Difference
Lower
Upper
-2.252
-2.252
3.706
3.706
-9.754
5.251
-9.755
5.252
Dokumentasi