Review Of Nasa Fibromyxoma: Aggressive Behaviour? (Case Report)
Editor-in-Chief
Prof. Dr. Sri Maliawan, SpBS
(Scopus ID= 15738530400, h-index= 3, [email protected])
Department of Neuro Surgery, Udayana University
Sanglah General Hospital
Bali - Indonesia
Associate Editor
Prof. Putra Manuaba, M.Phil
(Scopus ID= 8412278400, h-index= 1, [email protected])
Biomedicine Postgraduate Program, Udayana University
Bali - Indonesia
Editorial Board for Regional America
Ankit Sakhuja, M.B.B.S., F.A.C.P., F.A.S.N.
(Scopus ID= 16744977200, h-index= 8, [email protected])
Nephrology and Hypertension Cleveland Clinic (United States)
Editorial Board for Regional Australia
Prof. John Svigos, MB. BS. DRCOG., FRCOG., RANZCOG
(Scopus ID= 6603773825, h-index= 7 ,[email protected])
Ashford Hospital & Faculty of Health Sciences, University of Adelaide, Australia
Editorial Board for Regional Europa
Prof. Harald Hoekstra
(Scopus ID= 36038081900, h-index= 53 ,[email protected])
Universitair Medisch Centrum Groningen, Division of Surgical Oncology, Groningen the
Netherland
Prof. A. A. W. Peters, MD., PhD
(Scopus ID= 7402105952, h-index= 18, [email protected])
Leiden University Medical Center - LUMC, Department of Gynecology, Leiden, Netherland
Editorial Board for Regional Asia
Prof Huang Qin
(Scopus ID= 8570628900, h-index= 1, [email protected])
Chairman Dept. of Neurosurgery, Guangdong 999 Hospital Guangzhou China
Dr. P.S. Ramani M.D
(Scopus ID= 7003454654, h-index= 5, [email protected])
Professor and Head Dept. of Neurospinal Surgery, University of Mumbai-India
Prof. Soo Khee Chee
(Scopus ID= 7005885770, h-index= 8, [email protected])
SGH (Singapore General Hospital), National University Hospital, Duke Medical Center
Singapore
Prof. Shukla
(Scopus ID= 7103167378, h-index= 29, [email protected])
Banaras Hindu University Institute of Medical Sciences, Varanasi India
Dr. Junichi Mizuno, Ph.D
(Scopus ID= 7006425415, h-index= 16, [email protected])
Southern Tohoku General Hospital, Department of Neurosurgery, Iwanuma, Miyagi, Japan
Dr. G Sai sailesh Kumar, Ph.D
(Scopus ID= 56176035300, h-index= 5, [email protected])
Department of Physiology, Little Flower Institute of Medical Sciences and Research,
Angamaly, Kerala, India
Assoc. Prof. Mohammad Amin Bahrami
(Scopus ID= 55524082200, [email protected])
Head of healthcare management department, Shahid Sadoughi University of Medical
Sciences, Yazd, Iran
Editorial Board Members
Prof. Dr. dr. I Made Bakta, Sp.PD(KHOM)
(Scopus ID= 6603197439, h-index= 3, [email protected])
Udayana University, Sanglah General Hospital, Bali-Indonesia
Prof. Dr. dr. A. A. Raka Sudewi, Sp.S(K)
(Scopus ID= 12140226200, h-index= 2, [email protected])
Postgraduate Program Udayana University, Sanglah Hospital, Bali-Indonesia
Prof . Dr. dr. IB Tjakra Wibawa Manuaba SpB K.Onk MPH
(Scopus ID= 22953883500, h-index= 2, [email protected])
Udayana University, Sanglah General Hospital, Bali-Indonesia
Prof. Ketut Suwiyoga, SpOG
([email protected])
Faculty of Medicine, Udayana University, Sanglah Hospital Denpasar, Bali-Indonesia
Prof. Andi Asadul Islam
([email protected])
Faculty of Medicine Hasanudin University, Makasar-Indonesia
Prof. Dr. dr. Abdul Hafid Bajamal, Sp.BS
([email protected])
Faculty of Medicine Airlangga University, Surabaya-Indonesia
Prof. I Ketut Siki Kawiyana SpB, SpOrtho
([email protected])
Faculty of Medicine Udayana University, Sanglah General Hospital, Bali-Indonesia
Dr. AAGede Oka
([email protected])
Sanglah General Hospital, Bali-Indonesia
Dr. Sudarsa SpB
([email protected])
Sanglah General Hospital, Bali-Indonesia
Dr Steven Christian SPB
([email protected])
Sanglah General Hospital, Bali-Indonesia
Dr. Nyoman Semadi SpB
([email protected])
Thorax and Cardiovascular Surgery, Sanglah General Hospital, Bali-Indonesia
Dr. Wayan Sutarga
([email protected])
Sanglah General Hospital, Bali-Indonesia
Dr. dr. Tjokorda Gde Bagus Mahadewa, SpBS., M.Kes
(Scopus ID= 6507494320, h-index= 2, [email protected])
Sanglah General Hospital, Department of Neurosurgery, Indonesia
Prof. Dr. dr. Raka Widiana, SpPD KGH
([email protected])
Sanglah General Hospital, Bali-Indonesia
dr. I.B. Amertha P. Manuaba, SKed, MBiomed.
([email protected])
Biomedicine Magister Program, Udayana University, Indonesia
Editorial inquiries to be addressed to: [email protected]
ISSN: 2302-2914
Bali Medical Journal (Bali Med J) 2015, Volume 4, Number 3: 132-135
P-ISSN.2089-1180, E-ISSN.2302-2914
REVIEW OF NASA FIBROMYXOMA: Aggressive Behaviour?
(Case Report)
Rr. Suzy Indharty
Department of Neurosurgery, Faculty of Medicine, Sumatera Utara University/
Haji Adam Malik Hospital, Sumatra-Indonesia
Background: Myxomas are rare benign tumors arising from mesenchymal tissues throughout the
body. These tumors are usually seen in the atrium of the heart and the jawbone. Involvement of the
skull base with intracranial extension is extremely rare, and only a few cases of primary intracranial
myxomas have been described in the literature. This article presents a rare case of primary myxoma of
the nasal bone. Methods: The patient underwent a skull base surgery with a pre-diagnosis of possible
fibromyxomas. The tumor pathology revealed a diagnosis of myxoma with bone and meningeal
involvement. Despite the debulking surgery, the tumor showed a local recurrence in five month. A
second debulking surgery in piece meal was required. In the article, the etiology, histological and
radiological findings as well as treatment options of this rare entity were briefly discussed under the
highlights of the relevant literature. Such a localization and intracranial extension of myxomas is
extremely unusual in clinical practice; the diagnosis therefore requires a high degree of suspicion and
detailed histopathological examination. The differential diagnosis frequently includes
chondrosarcomas, chordoma, metastatic tumors of the skull, hemangiopericytoma, meningioma and
other neoplasms of the dura and skull base in this location.
KEYWORDS: Myxoma, Skull base, Temporal bone, Neoplasm.
INTRODUCTION
Myxomas are benign tumors of primitive
mesenchymal tissue, and are usually found in the
heart, skin, certain bones and genitalia.1 Myxomas
are locally invasive, benign mesenchymal neoplasms
with odontogenic, osteogenic, or soft tissue origin.
Facial myxomas probably account for less than 0.5%
of all paranasal sinus and nasal tumors. These
tumors may be primary or embolic from an
underlying cardiac myxoma. Primary myxomas of
the head and neck are rare lesions in clinical
practice, and usually involve the maxillofacial
skeleton. Myxomas are rare in children under 10
years of age. Although this tumor is reported most
frequently in the mandible for the general
population, it has rarely been reported in the
mandible in children
Prof. Dr. Sri Maliawan, SpBS
(Scopus ID= 15738530400, h-index= 3, [email protected])
Department of Neuro Surgery, Udayana University
Sanglah General Hospital
Bali - Indonesia
Associate Editor
Prof. Putra Manuaba, M.Phil
(Scopus ID= 8412278400, h-index= 1, [email protected])
Biomedicine Postgraduate Program, Udayana University
Bali - Indonesia
Editorial Board for Regional America
Ankit Sakhuja, M.B.B.S., F.A.C.P., F.A.S.N.
(Scopus ID= 16744977200, h-index= 8, [email protected])
Nephrology and Hypertension Cleveland Clinic (United States)
Editorial Board for Regional Australia
Prof. John Svigos, MB. BS. DRCOG., FRCOG., RANZCOG
(Scopus ID= 6603773825, h-index= 7 ,[email protected])
Ashford Hospital & Faculty of Health Sciences, University of Adelaide, Australia
Editorial Board for Regional Europa
Prof. Harald Hoekstra
(Scopus ID= 36038081900, h-index= 53 ,[email protected])
Universitair Medisch Centrum Groningen, Division of Surgical Oncology, Groningen the
Netherland
Prof. A. A. W. Peters, MD., PhD
(Scopus ID= 7402105952, h-index= 18, [email protected])
Leiden University Medical Center - LUMC, Department of Gynecology, Leiden, Netherland
Editorial Board for Regional Asia
Prof Huang Qin
(Scopus ID= 8570628900, h-index= 1, [email protected])
Chairman Dept. of Neurosurgery, Guangdong 999 Hospital Guangzhou China
Dr. P.S. Ramani M.D
(Scopus ID= 7003454654, h-index= 5, [email protected])
Professor and Head Dept. of Neurospinal Surgery, University of Mumbai-India
Prof. Soo Khee Chee
(Scopus ID= 7005885770, h-index= 8, [email protected])
SGH (Singapore General Hospital), National University Hospital, Duke Medical Center
Singapore
Prof. Shukla
(Scopus ID= 7103167378, h-index= 29, [email protected])
Banaras Hindu University Institute of Medical Sciences, Varanasi India
Dr. Junichi Mizuno, Ph.D
(Scopus ID= 7006425415, h-index= 16, [email protected])
Southern Tohoku General Hospital, Department of Neurosurgery, Iwanuma, Miyagi, Japan
Dr. G Sai sailesh Kumar, Ph.D
(Scopus ID= 56176035300, h-index= 5, [email protected])
Department of Physiology, Little Flower Institute of Medical Sciences and Research,
Angamaly, Kerala, India
Assoc. Prof. Mohammad Amin Bahrami
(Scopus ID= 55524082200, [email protected])
Head of healthcare management department, Shahid Sadoughi University of Medical
Sciences, Yazd, Iran
Editorial Board Members
Prof. Dr. dr. I Made Bakta, Sp.PD(KHOM)
(Scopus ID= 6603197439, h-index= 3, [email protected])
Udayana University, Sanglah General Hospital, Bali-Indonesia
Prof. Dr. dr. A. A. Raka Sudewi, Sp.S(K)
(Scopus ID= 12140226200, h-index= 2, [email protected])
Postgraduate Program Udayana University, Sanglah Hospital, Bali-Indonesia
Prof . Dr. dr. IB Tjakra Wibawa Manuaba SpB K.Onk MPH
(Scopus ID= 22953883500, h-index= 2, [email protected])
Udayana University, Sanglah General Hospital, Bali-Indonesia
Prof. Ketut Suwiyoga, SpOG
([email protected])
Faculty of Medicine, Udayana University, Sanglah Hospital Denpasar, Bali-Indonesia
Prof. Andi Asadul Islam
([email protected])
Faculty of Medicine Hasanudin University, Makasar-Indonesia
Prof. Dr. dr. Abdul Hafid Bajamal, Sp.BS
([email protected])
Faculty of Medicine Airlangga University, Surabaya-Indonesia
Prof. I Ketut Siki Kawiyana SpB, SpOrtho
([email protected])
Faculty of Medicine Udayana University, Sanglah General Hospital, Bali-Indonesia
Dr. AAGede Oka
([email protected])
Sanglah General Hospital, Bali-Indonesia
Dr. Sudarsa SpB
([email protected])
Sanglah General Hospital, Bali-Indonesia
Dr Steven Christian SPB
([email protected])
Sanglah General Hospital, Bali-Indonesia
Dr. Nyoman Semadi SpB
([email protected])
Thorax and Cardiovascular Surgery, Sanglah General Hospital, Bali-Indonesia
Dr. Wayan Sutarga
([email protected])
Sanglah General Hospital, Bali-Indonesia
Dr. dr. Tjokorda Gde Bagus Mahadewa, SpBS., M.Kes
(Scopus ID= 6507494320, h-index= 2, [email protected])
Sanglah General Hospital, Department of Neurosurgery, Indonesia
Prof. Dr. dr. Raka Widiana, SpPD KGH
([email protected])
Sanglah General Hospital, Bali-Indonesia
dr. I.B. Amertha P. Manuaba, SKed, MBiomed.
([email protected])
Biomedicine Magister Program, Udayana University, Indonesia
Editorial inquiries to be addressed to: [email protected]
ISSN: 2302-2914
Bali Medical Journal (Bali Med J) 2015, Volume 4, Number 3: 132-135
P-ISSN.2089-1180, E-ISSN.2302-2914
REVIEW OF NASA FIBROMYXOMA: Aggressive Behaviour?
(Case Report)
Rr. Suzy Indharty
Department of Neurosurgery, Faculty of Medicine, Sumatera Utara University/
Haji Adam Malik Hospital, Sumatra-Indonesia
Background: Myxomas are rare benign tumors arising from mesenchymal tissues throughout the
body. These tumors are usually seen in the atrium of the heart and the jawbone. Involvement of the
skull base with intracranial extension is extremely rare, and only a few cases of primary intracranial
myxomas have been described in the literature. This article presents a rare case of primary myxoma of
the nasal bone. Methods: The patient underwent a skull base surgery with a pre-diagnosis of possible
fibromyxomas. The tumor pathology revealed a diagnosis of myxoma with bone and meningeal
involvement. Despite the debulking surgery, the tumor showed a local recurrence in five month. A
second debulking surgery in piece meal was required. In the article, the etiology, histological and
radiological findings as well as treatment options of this rare entity were briefly discussed under the
highlights of the relevant literature. Such a localization and intracranial extension of myxomas is
extremely unusual in clinical practice; the diagnosis therefore requires a high degree of suspicion and
detailed histopathological examination. The differential diagnosis frequently includes
chondrosarcomas, chordoma, metastatic tumors of the skull, hemangiopericytoma, meningioma and
other neoplasms of the dura and skull base in this location.
KEYWORDS: Myxoma, Skull base, Temporal bone, Neoplasm.
INTRODUCTION
Myxomas are benign tumors of primitive
mesenchymal tissue, and are usually found in the
heart, skin, certain bones and genitalia.1 Myxomas
are locally invasive, benign mesenchymal neoplasms
with odontogenic, osteogenic, or soft tissue origin.
Facial myxomas probably account for less than 0.5%
of all paranasal sinus and nasal tumors. These
tumors may be primary or embolic from an
underlying cardiac myxoma. Primary myxomas of
the head and neck are rare lesions in clinical
practice, and usually involve the maxillofacial
skeleton. Myxomas are rare in children under 10
years of age. Although this tumor is reported most
frequently in the mandible for the general
population, it has rarely been reported in the
mandible in children