Uji In Vitro Aktivitas Antelmintik Ekstrak Etanol Daun Pugun Tanoh [Curanga fel-terrae (Lour.) Merr.]
DAFTAR PUSTAKA
Agung dan Tinton (eds). (2008). Buku Pintar Tanaman Obat. Cetakan 1, Jakarta :
Agromedia Pustaka. Halaman 64-65.
Asih, A. (2014). Antihelmintik Infusa Daun Andong (Cordyline fruticosa)
Terhadap Ascaridia galli secara in vitro. Jurnal. Universitas Atma Jaya
Yogyakarta. Halaman 1-10.
Albonico, M., Bickle, Q., Ramsan, M., Montresor, A., Savioli, L., Taylor, M.
(2003). Efficacy of Mebendazole and Levamisole Alone or In
Combination Against Intestinal Nematode Infections After Repeated
Targeted Mebendazole Treatment In Zanzibar. Bull. World Health
Organanization. 1(81): 343–352.
Bairagi, A.O., Kabra, dan R.J., Mandade. (2011). Anthelmintic Activity of
Lawsonia inermis L. Leaves in Indian Adult Earthworm. Int of Res Pharm
Biol Sci. 2(01): 237-240.
Bhawan, S., Hemalata, S., Sarla, S., Prakash, C.B., Somesh, T. (2011).
Anthelmintic Potential of Certain Ethano Medical Plants of Uttarakhand
State, India. J Chem Pharm Res. 3(5): 465-467.
Bidkar, J.S., Bhujbal, M.D., Ghanwa, D.D., Dama, G. Y. (2011). Antihelmintic
Activity of Citras aurantium Linn. Int J Pharm Res Dev. 3(3): 67-72.
Borah, S., Kakoti, B. B., Mahato, K., dan Kumar, M. (2013). Investigation of invitro Anthelmintic Acitivity of Calamus leptospadix Griff. Shoot in Indian
Adult Earthworm (Pheretima posthuma). J App Sci 3(06): 156-159.
Budiyanti, R.T. (2010). Efek Antihelmintik Infusa Herba Sambiloto
(Andrographis paniculata , Nees) Terhadap Ascaris suum Secara In
vitro.Skripsi. Universitas Sebelas Maret, Surakarta. Halaman 1-56.
Choudhary, G.P. (2013). Anthelmintic Activity of Leaves of Coleus aromaticus
Benth. Int. J Adv Pharm Bio Chem. 2(4): 609-610.
Dhaked, P.S., Ponigrahy, R.N., Kshirsagar, S. (2011). In-vitro Evaluation of
Anthelmintic Activity of Caesalpinia pulcherima (Linn.) Flowers Extracts
in Indian Earth Worms. Int J Pharm Sci Rev Res. 7(1): 89-91.
Data, SC. (2003). Fourth Edition Sistematic Botany. New Delhi: New age
international (P) ltd. Publishers. Halaman 446.
Direktorat Jenderal Pengawasan Obat dan Makanan. (1995). Farmakope
Indonesia . Edisi IV. Jakarta: Departemen Kesehatan RI. Halaman 10301031.
47
Universitas Sumatera Utara
Direktorat Jenderal Pengawasan Obat dan Makanan. (1995). Materia Medika
Indonesia . Jilid VI. Jakarta: Departemen Kesehatan RI. Halaman 319-320.
Direktorat Jenderal Pengawasan Obat dan Makanan. (2000). Parameter Standar
Umum Ekstrak Tumbuhan Obat. Jakarta: Departemen Kesehatan
RI.Halaman 3, 7-8, 10, dan 11.
Djatmiko, M., Purnowati, L.D., dan Suhardjono. (2009). Uji Daya Antelmintik
Biji Waluh (Cucurbita moschata Durch) Terhadap Cacing Ascaridia galli
Secara In Vitro. Jurnal Ilmu Farmasi dan Farmasi Klinik. 6(1): 12-17.
Dorland, W.A.N (2012). Kamus Saku Kedokteran Dorland Edisi Ke XXVII.
Jakarta: Penerbit Buku Kedokteran EGC. Halaman 581.
Entjang, I. (2003). Mikrobiologi dan Parasitologi untuk Akademi Keperawatan
dan Sekolah Tenaga Kesehatan yang Sederajat . Bandung: PT. Citra
Aditya Bakti. Halaman 229-230.
Fang, H, Ning, D.S., and Liang, X.Y. (2009). Studies on Technology
Optimization for Extracting Triterpenoid Saponins from Picria felterrae by
Multi-target Grading Method. Zhong Yao Cai. 32(12): 1902-1905.
Fithra, R.S. (2013). Efek Penyembuhan Luka Bakar dari Sediaan Gel Ekstrak
Etanol Daun Puguh Tanoh (Curanga fel-terrae (Lour.) Merr.). Skripsi.
Medan: Fakultas Farmasi USU. Halaman 10-12.
Fitri, Sri, A. (2005). Uji In Vivo Efek Antelmintik Serbuk Kulit Buah Nanas
Bogor Tua Terhadap cacing Lambung Domba. Seminar Nasional
Teknologi Peternakan dan Veteiner. Halaman 724-731.
Flohr, C., Tuyen, L.N., Lewis, S., Minh, T.T., Campbell, J., Britton, J., Williams,
H., Hien, T.T., Farrar, J., Quinnell, R.J. (2007). Low Efficacy of
Mebendazole Against Hook Worm in Vietnam: Two Randomized
Controlled Trials. Am. J. Trop. Med. Hyg. Halaman 76, 732–736.
Farnsworth, N.R. (1966). Biological and phytochemical screening of plants. J
Pharm Sci. 55(3): 99; 225-276.
Githiori, J.B., Athanasiadou, S., Thamsborg, S.M. (2006). Use of Plants in Novel
Approaches for Control of Gastrointestinal Helminths in Livestock with
Emphasis on Small Ruminants. Veterinary Parasitology. 139:308-20.
Globinmed. (2015). Detil Data Picria fel-terrae. [Diakses 15 Maret 2015];
Diambil dari file:///H:/penelitian/web/Globinmed%20%20Globinmed.htm.
Gunawan dan Sulistia (eds). (2011). Farmakologi dan Terapi. Cetakan Kelima.
Jakarta: Badan Penerbit FKUI. Halaman 545-546.
48
Universitas Sumatera Utara
Harahap, U., Patilaya, P., Marianne, Yuliasmi, S., Husori, D.I., Prasetyo, B.E.,
Laila, L., Sumantri, I.B., dan Wahyuni, H.S. (2013). Profil Fitokimia
Ekstrak Etanol Daun Puguntano [Curanga fel-terrae (Merr.) Lour.)] yang
Berpotensi Sebagai Antiasma. Prosiding Seminar Nasional Sains dan
Teknologi V Lembaga Penelitian Universitas Lampung.Halaman 422-426.
Harborne, J.B. (1987). Metode Fitokimia . Penerjemah: Kosasih Padmawinata dan
Iwang Soediro. Edisi II. Bandung: Penerbit ITB. Halaman 102-103, 152.
Harfina, F., Bahri, S., dan Saragih, A. (2012). Pengaruh Serbuk Daun Puguntano
(Curanga fel-terrae Merr.) Pada Pasien Diabetes Mellitus. Journal of
Pharmaceutics and Pharmacology. 2(1): 112-118.
Hoste, H., Jackson, F., Athanasiadou, S., Thamsborg, S.M., dan Hoskin, S.O.
(2006). The Effects of Tannin-rich Plants on Parasitic Nematodes in
Ruminants. Trends in Parasitology. 22:253-61.
Huang Y, de Bruyne T, Apers S, Ma Y, Claeys M, Pieters L, Vlietinck A. (1999).
Flavonoid Glucuronides from Picria fel-terrae. Phytochemistry. 62(8):
1701- 1703.
Huang Y, de Bruyne T, Apers S, Ma Y, Claeys M, van den Berghe D, Pieters L,
Vlietinck, A. (1998). Complement-Inhibiting Cucurbitacin Glycosides
from Picria felterrae. Journal of Natural Products. 61(6): 757-761.
Humphries, D., Mosites, E., Otchere, J., Twum, W.A., Woo, L., Jones-Sanpei, H.,
Harrison, L.M., Bungiro, R.D., Benham-Pyle, B., Bimi, L., Edoh, D.,
Bosompem, K., Wilson, L.M., Cappello, M.. (2011). Epidemiology of
Hookworm Infection in Kintampo North Municipality, Ghana: Patterns of
Malaria Coinfection, Anaemia, and Albendazole Treatment Failure. Am. J.
Trop. Med. Hyg. Halaman 84, 792–800.
Irianto, K. (2013). Parasitologi Medis. Bandung: Alfabeta. Halaman 350-351.
Jie, M.Z., Li, S.W., Ya, J.G., Zheng, W., and Rui, Z.W., A. (2005). New
Picfeltarraenone Glycoside from Picria fel-terrae Merr. Guilin Sanjin
Pharmaceutical Co. Ltd. 3:12.
Jeyathilakan, N., Murali, K., Anandaraj, A., Latha, B.R. dan Basith, S.A. (2010).
Anthelmintic Activity of Essential Oils of Cymbopogan nardus and
Azadirachta indica on Fasciola gigantica. Tamilnadu J Veterinary and
Animal Sciences.6(5): 204-209.
Joseph, T.S.O., Ofodile, L.N. dan Oguntoke, T. (2013). In Vitro evaluation of
anthelmintic activity of crude extract of the leaves of Dalberqiella
welwitschii. Int J Pharm Pharm Sci. 5(1): 33-34.
49
Universitas Sumatera Utara
Juwita, N. A. (2009). Karakterisasi simplisia dan uji efek antiinflamasi ekstrak
etanol daun pugun tanoh (Curanga fel-terrae Merr.) terhadap mencit
jantan. Skripsi. Medan: Fakultas Farmasi USU. Halaman 43-46.
Katikia, L.M., Chagasb, A.C.S., Bizzoc, H.R. (2011). Anthelmintic Activity of
Cymbopogon martini, Cymbopogon schoenanthus and Mentha piperita
Essential Oils Evaluated in Four Different In Vitro Test. Veterinary
Parasitology. 183: 103-108.
Kementrian Kesehatan Republik Indonesia. (2015). Kemenkes Berkomitmen
Eliminasi Filariasis dan Kecacingan. [diakses 6 Agustus 2015];
Diambil
dari
:http://www.depkes.go.id/article/view/2382/kemenkesberkomitmen- eliminasi-filariasis-dan-kecacingan.html.
Kotze, A.C., Cowling, K., Bagnall, N.H., Hines, B.M., Ruffell, A.P., Hunt, P.W.,
Coleman, G.T. (2009). Relative level of thiabendazole resistance
associated with the E198A and F200Y SNPs in larvae of a multi-drug
resistant isolate of Haemonchus contortus. Int. J. Parasitol. Drugs Drug.
Resist. Halaman 2, 92–97.
Lalchhandama, K. (2010). Anthelmintic Resistance: The Song Remains The
Same. Research Review Sa Vis, 10(4): 111-122.
Lansdown, R.V. (2011). Curanga amara. The IUCN Red List of Threatened
Species:http://dx.doi.org/10.2305/IUCN.UK.20112.RLTS.T199703A9120
155.en.
Lewis, W. (2003). Medical botany. Plants affecting human health . John Wiley
and sons, Inc, Halaman 515.
Leo, L.X. and Weller, P.F. (1996). An update on antiparasitic drugs. N Engl J
Med, 334(18): 1178-1184.
Makkar, H. P. S. (1993). Antinutritional Factor in Food for Livestock in Animal
Producting in Developing Country. British Society of Animal Production.
16: 69-85.
Mokoginta, E.P., Runtuwene, M.R.J., Wehantow, F. (2013). Pengaruh Ekstraksi
Terhadap Aktivitas Penangkal Radikal Bebas Ekstrak Metanol Kulit Biji
Pinang (Areca vestriaria Giselie). Pharmacon Jurnal Ilmiah Farmasi.
2(4).
Mughal, T.A., Arshad, S., and Mahboob, S. (2013). Evaluation of Anthelmintic
Activity of Some Members of Family Moraceae. J Med Plants Res.
7(30): 2275-2279.
Mukherjee, P. dan Houghton, P.J. (2009). Evaluation of Herbal Medicinal
Products. USA: Pharmaceutical Press. Halaman 86.
50
Universitas Sumatera Utara
Nitave, S.A., Patil, V.A. (2014). Comparative Evaluation of Anthelmintic Activity
of Nerium indicum, Mill Flower Extract and Punica granatum, Linn peel
and seed eztract in 1:1 Ratio and their Phytochemical Screening. Wrld J
Pharm Pharm Sci. 3(06): 1438-1447.
Padal, S.B., Satyavathi, D. Sandhyadeepika. (2014). Ethnomedical Plants Used
For
Anthelmintic/Helminthiasis
in
Visakhapatnam
District,
Andhrapradesh, India. Int J Ethno Ethno. 1(02): 1-5.
Pagariya, A., Chatur, S., dan Nawab, F. (2013). In Vitro anthelmintic activity of
root extract of Murraya koenigii (Linn) Spreng. Int J Pharmaceut Innov.
3(1): 111-114.
Patilaya, P., Husori, D.I. (2015). Preliminary Study on the Anthelmintic Activity
of the leaf ethanolic extract of Indonesian Curanga fe-terrae (Lour.) Merr.
Int J PharmTech Res. 8(3): 347-351.
Perry, L.M. (1980). Medicinal Plants of East and Southeast Asia . London: The
MIT Press. Halaman 384.
Prichard, R.K. (2007). Parasitology: Markers for benzimidazole resistance in
human parasitic nematodes? . United Kingdom: Cambridge University
Press. 134: 1087-1092.
Prohati. (2015). Detil Data Picria fel-terrae Lour . [Diakses 6 Maret 2015];
Diambil dari http://www.proseanet.org/prohati2/browser.php?docsid=459.
Quattrocchi, F.L.S., Umberto. (2012). CRC World Dictionary of Medicinal and
Poisonous Plants, Common Names, Scientific Names, Eponyms,
Synonyms, and Etymology. Francis: CRC Press. Halaman 2925.
Ramadhani, D. (2014). Efek relaksasi ekstrak etanol daun pugun tanoh (Curanga
fel-terrae (Lour.) Merr.) terhadap otot polos trakea marmut terisolasi dan
pengaruhnya pada fosfodiesterase. Skripsi. Medan: Fakultas Farmasi USU.
Halaman 36-38.
Rajani, A., Hemamalini, K., Satyavati, D., Begum, A.S.K., Saradhi., N.D.V.R.
(2013). Anthelmintic Activity of Methanolic Extract of Rhizomes of
Picrorrhiza kurroa Royal Ex. Benth. Int Res J Pharm 4(8): 143-144.
Ratnawati, D., Supriyati, R., dan Ispamuji, D. (2013). Aktivitas antelmintik
ekstrak tanaman putri malu (Mimosa pudicia L) terhadap cacing gelang
babi (Ascaris suum L). Posiding Semirata FMIPA Universitas Lampung :
Halaman 87-91.
Reynoldson JA, Behnke JM, Pallant LJ, Macnish MG, Gilbert F, Giles S, Spargo
RJ & Thompson RC (1997). Failure of pyrantel in treatment of human
51
Universitas Sumatera Utara
hookworm infections (Ancylostoma duodenale) in the Kimberley region of
North West Australia. Acta Trop. Halaman 68, 301-312.
Sanbayu, M.N.F. (2005) Efek Anthelmintik Ekstrak Air Kulit Buah Delima
(Punica granatum L.) Terhadap Cacing Gelang (Ascaris Lumbricoides
var. suum) Secara In Vitro dan In Vivo.Tesis. Universitas Surabaya.
Halaman 19.
Senja, R.Y., Issusilaningtyas, E., Nugroho, A.K., Setyowati, E.P. (2014). The
Comparison of Extraction Method and Solvent Variation on Yield and
Antioxidant Activity of Brassica oleracea L. Var capitata f. Rubra Extract.
Trad Med J. 19(1): 43-48.
Shahidi, F and M. Naczk. (1995). Food Phenolics. Technomic Inc, Basel.
Halaman 302.
Sharma, A., Gupta, S., Sachan, S., Mishra, A., Banarji, A. (2011). Anthelmintic
Activity of Leaf of Saraca indica Linn. As J Pharm Life Sci.1(4): 391395.
Sharma. S.K. (2010). Objective Zoology. India: KHRISHNA Prakash Media.
Halaman 2200-2261.
Shri, V.K., Senthamarai, R., Vasuki, K., Venkateswara, R.A., Selvadurai, S.
(2011). Anthelmintic Activity of Roots and Rhizomes of Corallocarpus
epigaeus. J Nat Prod Plant Resour . 1(1): 81-84.
Sitorus, P., Harahap, U., Pandapotan, M., dan Barus, T. (2014). Isolation Of βSitosterol From n-Hexane of Picria fel-terrae Lour. Leave and Study Of Its
Antidiabetic Effect in Alloxan Induced Diabetic Mice. International
Journal of PharmTech Research. 6(1): 137-141.
Soedarto. (2008). Parasitologi Klinik. Surabaya: Airlangga University Press.
Halaman 11.
Subash, K.R., Rao, N.J., Cheriyan, B.V., Bhaarati, G.M., Kumar, K. S. (2012).
The Antelmintic Activity of Eupatorium triplinerve and Alpinia galanga
in Pheretima posthuma and Ascardia galli: A Comparative Study. J Clin
Diag Res. 6(06): 947-950.
Sutherland, I.A., Leathwick, D.M. (2011). Anthelmintic Resistance in Nematode
Parasites of Cattle: A Global Issue? Trends Parasitol. Halaman 27, 176–
181.
Sykur, C. Dan Hernani. (2002). Budidaya Tanaman Obat Komersial. Penebar
Swadaya, Jakarta. Halaman 136.
Tekeshwar, K., Amit, A., Ajazuddin, Dhansay, D., Kushangra, N. (2011).
Anthelmintic Activity of the Whole Plant of Bauhinia purpurea (Linn.).
Asian Journal of Pharmaceutical and Clinical Research . 4(3): 110-111).
52
Universitas Sumatera Utara
Tiwow, D., Bodhi, W., dan Kojong, N.S. (2013). Uji Efek Antelmintik Ekstrak
Etanol Biji Pinang (Areca catechu)
Terhadap Cacing Ascaris
Lumbricoides dan Ascaridia Galii secara In Vitro. Pharmacon jurnal
ilmiah farmasi UNSRAT.2(2): 79-80.
Tjay, T.H., dan Rahardja, K. (2002). Obat Obat Penting Khasiat, Penggunaan
dan Efek-Efek Sampingnya . Edisi keempat. Jakarta.PT Elexmedia
komputindo kelompok gramedia. Halaman 196 – 205.
Tjahyanto, A. Dan Salim, C. (eds). (2013). Farmakologi Ulasan Bergambar .
Jakarta: EGC. Halaman 513-520.
Tjokropranoto, R., Rosnaeni, Nathania. M.Y. (2011). Anthelmintic Effect of
Ethanol Extract of Pare Leaf (Momordica charantia L.) Against Female
Ascaris suum Worm In Vitro, Jurnal Medika Planta . 1(4): 1334-1336.
Tyler , V.E. (1976). Pharmacognosy. Lea & Febiger, Philadelphia. Halaman 8789.
Urban, J., Kokoska, L., Langrova, I., and Matejkova, J. (2015). In Vitro
Anthelmintic Effects of Medicinal Plants Used in Czech Republic. 46(1011): 808-813.
Vennila V and Nivetha R. (2015). Screening The In vitro anthelmintic activity of
Alternanthera sessilis Leaves. Wrld J Pharm Pharm Sci. 4(04): 14021415.
Vercruysse, J., Behnke, J.M., Albonico, M., Ame, S.M., Angebault, C., Bethony,
J.M., Engels, D., Guillard, B., Hoa, N.T., Kang, G., Kattula, D., Kotze,
A.C., McCarthy, J.S., Mekonnen, Z., Montresor, A., Periago, M.V., Sumo,
L., Tchuem Tchuenté, L.A., Thach, D.T., Zeynudin, A., Levecke, B.
(2011). Assessment of The Anthelmintic Efficacy of Albendazole in
School Children in Seven Countries Where Soiltransmitted Helminths Are
Endemic. P Lo S Negl. Trop. Dis. Halaman 29, e948.
Vercruysse, J., Albonico, M., Behnke, J.M., Kotze, A.C., Prichard, R.K.,
McCarthy, J.S., Montresor, A., Levecke, B. (2011). Is Anthelmintic
Resistance a Concern For The Control of Human Soil-Transmitted
Helminths?. Int J Paras: Drug and Drug Resistance. 1(2011): 14-27.
Vincent, S., Vijayamirtharaj, R., Wilson, P., Saravanan, B., Jeevantham, R.,
Ramesh, R. (2011). Anthelmintic potential of Aerial Part of Clerodendrum
phlomidis Linn, Research Journal of Pharmaceutical, Biological and
Chemical Sciences. 2(2): 329-333.
Wang LS, Li SH, Zou JM, Guo YJ, Sun HD. (2006). Two New Terpenoids from
Picria fel-terrae. Journal of Asian Natural Product Research . 8(6): 491 494.
Wolstenholme, A.J., Fairweather, I., Prichard, R., von Samson-Himmelstjerna, G.,
Sangster, N.C. (2004). Drug resistance in veterinary helminths. Trends
Parasitol. Halaman 20, 469–476
53
Universitas Sumatera Utara
World Health Organization. (2015). Soil-Transmitted Helminth Infections.
[Diakses 18 Juli 2015]; diambil dari http://www.who.int/media
centre/factsheets/fs366/en/.
World Health Organization. (2011). Quality Control Methods For Medicinal
Plant Material. Switzherland: WHO. Halaman 19-25.
Wink, M. (2012). Medical plants: A Source of Anti Parasitic Secondary
Metabolites. Molecules. 17: 12771-12791.
Wynn, S.G., Fougere, B.J. (2007). Introduction: Why Use Herbal Medicine.
Dalam: Wynn, S.G., Fougere, B.J. (Ed). Veterinary Herbal Medicine:
Library of Congress Cataloging-in Publication Data . ISBN: 10:0-323029981.
Zhong, S.Q., Zhang, B.N., dan Huang, F.X. (1979). An Anti-Tumor Herb Cucao.
China: Chin Tradit Herb Drugs Lett 3 . Halaman 45–46.
Zou JM, Wang LS, Ma XM, Shi RB, Guo YJ. (2004). Isolation and Identification
of A New Cucurbitacin from Picria fel-terrae. Acta Pharmacutica Sinica .
39(11): 910-912.
Zou JM, Wang LS, Niu XM, Sun HD, Guo YJ. (2005). Phenylethanoid
Glycosides from Picria felterrae Lour. Journal of Integrative Plant
Biology. 47(5): 632-636.
Zulkoni, H. Akhsin. (2010). Parasitologi. Yogyakarta: Nuha Medika. Halaman
71-72.
54
Universitas Sumatera Utara
Agung dan Tinton (eds). (2008). Buku Pintar Tanaman Obat. Cetakan 1, Jakarta :
Agromedia Pustaka. Halaman 64-65.
Asih, A. (2014). Antihelmintik Infusa Daun Andong (Cordyline fruticosa)
Terhadap Ascaridia galli secara in vitro. Jurnal. Universitas Atma Jaya
Yogyakarta. Halaman 1-10.
Albonico, M., Bickle, Q., Ramsan, M., Montresor, A., Savioli, L., Taylor, M.
(2003). Efficacy of Mebendazole and Levamisole Alone or In
Combination Against Intestinal Nematode Infections After Repeated
Targeted Mebendazole Treatment In Zanzibar. Bull. World Health
Organanization. 1(81): 343–352.
Bairagi, A.O., Kabra, dan R.J., Mandade. (2011). Anthelmintic Activity of
Lawsonia inermis L. Leaves in Indian Adult Earthworm. Int of Res Pharm
Biol Sci. 2(01): 237-240.
Bhawan, S., Hemalata, S., Sarla, S., Prakash, C.B., Somesh, T. (2011).
Anthelmintic Potential of Certain Ethano Medical Plants of Uttarakhand
State, India. J Chem Pharm Res. 3(5): 465-467.
Bidkar, J.S., Bhujbal, M.D., Ghanwa, D.D., Dama, G. Y. (2011). Antihelmintic
Activity of Citras aurantium Linn. Int J Pharm Res Dev. 3(3): 67-72.
Borah, S., Kakoti, B. B., Mahato, K., dan Kumar, M. (2013). Investigation of invitro Anthelmintic Acitivity of Calamus leptospadix Griff. Shoot in Indian
Adult Earthworm (Pheretima posthuma). J App Sci 3(06): 156-159.
Budiyanti, R.T. (2010). Efek Antihelmintik Infusa Herba Sambiloto
(Andrographis paniculata , Nees) Terhadap Ascaris suum Secara In
vitro.Skripsi. Universitas Sebelas Maret, Surakarta. Halaman 1-56.
Choudhary, G.P. (2013). Anthelmintic Activity of Leaves of Coleus aromaticus
Benth. Int. J Adv Pharm Bio Chem. 2(4): 609-610.
Dhaked, P.S., Ponigrahy, R.N., Kshirsagar, S. (2011). In-vitro Evaluation of
Anthelmintic Activity of Caesalpinia pulcherima (Linn.) Flowers Extracts
in Indian Earth Worms. Int J Pharm Sci Rev Res. 7(1): 89-91.
Data, SC. (2003). Fourth Edition Sistematic Botany. New Delhi: New age
international (P) ltd. Publishers. Halaman 446.
Direktorat Jenderal Pengawasan Obat dan Makanan. (1995). Farmakope
Indonesia . Edisi IV. Jakarta: Departemen Kesehatan RI. Halaman 10301031.
47
Universitas Sumatera Utara
Direktorat Jenderal Pengawasan Obat dan Makanan. (1995). Materia Medika
Indonesia . Jilid VI. Jakarta: Departemen Kesehatan RI. Halaman 319-320.
Direktorat Jenderal Pengawasan Obat dan Makanan. (2000). Parameter Standar
Umum Ekstrak Tumbuhan Obat. Jakarta: Departemen Kesehatan
RI.Halaman 3, 7-8, 10, dan 11.
Djatmiko, M., Purnowati, L.D., dan Suhardjono. (2009). Uji Daya Antelmintik
Biji Waluh (Cucurbita moschata Durch) Terhadap Cacing Ascaridia galli
Secara In Vitro. Jurnal Ilmu Farmasi dan Farmasi Klinik. 6(1): 12-17.
Dorland, W.A.N (2012). Kamus Saku Kedokteran Dorland Edisi Ke XXVII.
Jakarta: Penerbit Buku Kedokteran EGC. Halaman 581.
Entjang, I. (2003). Mikrobiologi dan Parasitologi untuk Akademi Keperawatan
dan Sekolah Tenaga Kesehatan yang Sederajat . Bandung: PT. Citra
Aditya Bakti. Halaman 229-230.
Fang, H, Ning, D.S., and Liang, X.Y. (2009). Studies on Technology
Optimization for Extracting Triterpenoid Saponins from Picria felterrae by
Multi-target Grading Method. Zhong Yao Cai. 32(12): 1902-1905.
Fithra, R.S. (2013). Efek Penyembuhan Luka Bakar dari Sediaan Gel Ekstrak
Etanol Daun Puguh Tanoh (Curanga fel-terrae (Lour.) Merr.). Skripsi.
Medan: Fakultas Farmasi USU. Halaman 10-12.
Fitri, Sri, A. (2005). Uji In Vivo Efek Antelmintik Serbuk Kulit Buah Nanas
Bogor Tua Terhadap cacing Lambung Domba. Seminar Nasional
Teknologi Peternakan dan Veteiner. Halaman 724-731.
Flohr, C., Tuyen, L.N., Lewis, S., Minh, T.T., Campbell, J., Britton, J., Williams,
H., Hien, T.T., Farrar, J., Quinnell, R.J. (2007). Low Efficacy of
Mebendazole Against Hook Worm in Vietnam: Two Randomized
Controlled Trials. Am. J. Trop. Med. Hyg. Halaman 76, 732–736.
Farnsworth, N.R. (1966). Biological and phytochemical screening of plants. J
Pharm Sci. 55(3): 99; 225-276.
Githiori, J.B., Athanasiadou, S., Thamsborg, S.M. (2006). Use of Plants in Novel
Approaches for Control of Gastrointestinal Helminths in Livestock with
Emphasis on Small Ruminants. Veterinary Parasitology. 139:308-20.
Globinmed. (2015). Detil Data Picria fel-terrae. [Diakses 15 Maret 2015];
Diambil dari file:///H:/penelitian/web/Globinmed%20%20Globinmed.htm.
Gunawan dan Sulistia (eds). (2011). Farmakologi dan Terapi. Cetakan Kelima.
Jakarta: Badan Penerbit FKUI. Halaman 545-546.
48
Universitas Sumatera Utara
Harahap, U., Patilaya, P., Marianne, Yuliasmi, S., Husori, D.I., Prasetyo, B.E.,
Laila, L., Sumantri, I.B., dan Wahyuni, H.S. (2013). Profil Fitokimia
Ekstrak Etanol Daun Puguntano [Curanga fel-terrae (Merr.) Lour.)] yang
Berpotensi Sebagai Antiasma. Prosiding Seminar Nasional Sains dan
Teknologi V Lembaga Penelitian Universitas Lampung.Halaman 422-426.
Harborne, J.B. (1987). Metode Fitokimia . Penerjemah: Kosasih Padmawinata dan
Iwang Soediro. Edisi II. Bandung: Penerbit ITB. Halaman 102-103, 152.
Harfina, F., Bahri, S., dan Saragih, A. (2012). Pengaruh Serbuk Daun Puguntano
(Curanga fel-terrae Merr.) Pada Pasien Diabetes Mellitus. Journal of
Pharmaceutics and Pharmacology. 2(1): 112-118.
Hoste, H., Jackson, F., Athanasiadou, S., Thamsborg, S.M., dan Hoskin, S.O.
(2006). The Effects of Tannin-rich Plants on Parasitic Nematodes in
Ruminants. Trends in Parasitology. 22:253-61.
Huang Y, de Bruyne T, Apers S, Ma Y, Claeys M, Pieters L, Vlietinck A. (1999).
Flavonoid Glucuronides from Picria fel-terrae. Phytochemistry. 62(8):
1701- 1703.
Huang Y, de Bruyne T, Apers S, Ma Y, Claeys M, van den Berghe D, Pieters L,
Vlietinck, A. (1998). Complement-Inhibiting Cucurbitacin Glycosides
from Picria felterrae. Journal of Natural Products. 61(6): 757-761.
Humphries, D., Mosites, E., Otchere, J., Twum, W.A., Woo, L., Jones-Sanpei, H.,
Harrison, L.M., Bungiro, R.D., Benham-Pyle, B., Bimi, L., Edoh, D.,
Bosompem, K., Wilson, L.M., Cappello, M.. (2011). Epidemiology of
Hookworm Infection in Kintampo North Municipality, Ghana: Patterns of
Malaria Coinfection, Anaemia, and Albendazole Treatment Failure. Am. J.
Trop. Med. Hyg. Halaman 84, 792–800.
Irianto, K. (2013). Parasitologi Medis. Bandung: Alfabeta. Halaman 350-351.
Jie, M.Z., Li, S.W., Ya, J.G., Zheng, W., and Rui, Z.W., A. (2005). New
Picfeltarraenone Glycoside from Picria fel-terrae Merr. Guilin Sanjin
Pharmaceutical Co. Ltd. 3:12.
Jeyathilakan, N., Murali, K., Anandaraj, A., Latha, B.R. dan Basith, S.A. (2010).
Anthelmintic Activity of Essential Oils of Cymbopogan nardus and
Azadirachta indica on Fasciola gigantica. Tamilnadu J Veterinary and
Animal Sciences.6(5): 204-209.
Joseph, T.S.O., Ofodile, L.N. dan Oguntoke, T. (2013). In Vitro evaluation of
anthelmintic activity of crude extract of the leaves of Dalberqiella
welwitschii. Int J Pharm Pharm Sci. 5(1): 33-34.
49
Universitas Sumatera Utara
Juwita, N. A. (2009). Karakterisasi simplisia dan uji efek antiinflamasi ekstrak
etanol daun pugun tanoh (Curanga fel-terrae Merr.) terhadap mencit
jantan. Skripsi. Medan: Fakultas Farmasi USU. Halaman 43-46.
Katikia, L.M., Chagasb, A.C.S., Bizzoc, H.R. (2011). Anthelmintic Activity of
Cymbopogon martini, Cymbopogon schoenanthus and Mentha piperita
Essential Oils Evaluated in Four Different In Vitro Test. Veterinary
Parasitology. 183: 103-108.
Kementrian Kesehatan Republik Indonesia. (2015). Kemenkes Berkomitmen
Eliminasi Filariasis dan Kecacingan. [diakses 6 Agustus 2015];
Diambil
dari
:http://www.depkes.go.id/article/view/2382/kemenkesberkomitmen- eliminasi-filariasis-dan-kecacingan.html.
Kotze, A.C., Cowling, K., Bagnall, N.H., Hines, B.M., Ruffell, A.P., Hunt, P.W.,
Coleman, G.T. (2009). Relative level of thiabendazole resistance
associated with the E198A and F200Y SNPs in larvae of a multi-drug
resistant isolate of Haemonchus contortus. Int. J. Parasitol. Drugs Drug.
Resist. Halaman 2, 92–97.
Lalchhandama, K. (2010). Anthelmintic Resistance: The Song Remains The
Same. Research Review Sa Vis, 10(4): 111-122.
Lansdown, R.V. (2011). Curanga amara. The IUCN Red List of Threatened
Species:http://dx.doi.org/10.2305/IUCN.UK.20112.RLTS.T199703A9120
155.en.
Lewis, W. (2003). Medical botany. Plants affecting human health . John Wiley
and sons, Inc, Halaman 515.
Leo, L.X. and Weller, P.F. (1996). An update on antiparasitic drugs. N Engl J
Med, 334(18): 1178-1184.
Makkar, H. P. S. (1993). Antinutritional Factor in Food for Livestock in Animal
Producting in Developing Country. British Society of Animal Production.
16: 69-85.
Mokoginta, E.P., Runtuwene, M.R.J., Wehantow, F. (2013). Pengaruh Ekstraksi
Terhadap Aktivitas Penangkal Radikal Bebas Ekstrak Metanol Kulit Biji
Pinang (Areca vestriaria Giselie). Pharmacon Jurnal Ilmiah Farmasi.
2(4).
Mughal, T.A., Arshad, S., and Mahboob, S. (2013). Evaluation of Anthelmintic
Activity of Some Members of Family Moraceae. J Med Plants Res.
7(30): 2275-2279.
Mukherjee, P. dan Houghton, P.J. (2009). Evaluation of Herbal Medicinal
Products. USA: Pharmaceutical Press. Halaman 86.
50
Universitas Sumatera Utara
Nitave, S.A., Patil, V.A. (2014). Comparative Evaluation of Anthelmintic Activity
of Nerium indicum, Mill Flower Extract and Punica granatum, Linn peel
and seed eztract in 1:1 Ratio and their Phytochemical Screening. Wrld J
Pharm Pharm Sci. 3(06): 1438-1447.
Padal, S.B., Satyavathi, D. Sandhyadeepika. (2014). Ethnomedical Plants Used
For
Anthelmintic/Helminthiasis
in
Visakhapatnam
District,
Andhrapradesh, India. Int J Ethno Ethno. 1(02): 1-5.
Pagariya, A., Chatur, S., dan Nawab, F. (2013). In Vitro anthelmintic activity of
root extract of Murraya koenigii (Linn) Spreng. Int J Pharmaceut Innov.
3(1): 111-114.
Patilaya, P., Husori, D.I. (2015). Preliminary Study on the Anthelmintic Activity
of the leaf ethanolic extract of Indonesian Curanga fe-terrae (Lour.) Merr.
Int J PharmTech Res. 8(3): 347-351.
Perry, L.M. (1980). Medicinal Plants of East and Southeast Asia . London: The
MIT Press. Halaman 384.
Prichard, R.K. (2007). Parasitology: Markers for benzimidazole resistance in
human parasitic nematodes? . United Kingdom: Cambridge University
Press. 134: 1087-1092.
Prohati. (2015). Detil Data Picria fel-terrae Lour . [Diakses 6 Maret 2015];
Diambil dari http://www.proseanet.org/prohati2/browser.php?docsid=459.
Quattrocchi, F.L.S., Umberto. (2012). CRC World Dictionary of Medicinal and
Poisonous Plants, Common Names, Scientific Names, Eponyms,
Synonyms, and Etymology. Francis: CRC Press. Halaman 2925.
Ramadhani, D. (2014). Efek relaksasi ekstrak etanol daun pugun tanoh (Curanga
fel-terrae (Lour.) Merr.) terhadap otot polos trakea marmut terisolasi dan
pengaruhnya pada fosfodiesterase. Skripsi. Medan: Fakultas Farmasi USU.
Halaman 36-38.
Rajani, A., Hemamalini, K., Satyavati, D., Begum, A.S.K., Saradhi., N.D.V.R.
(2013). Anthelmintic Activity of Methanolic Extract of Rhizomes of
Picrorrhiza kurroa Royal Ex. Benth. Int Res J Pharm 4(8): 143-144.
Ratnawati, D., Supriyati, R., dan Ispamuji, D. (2013). Aktivitas antelmintik
ekstrak tanaman putri malu (Mimosa pudicia L) terhadap cacing gelang
babi (Ascaris suum L). Posiding Semirata FMIPA Universitas Lampung :
Halaman 87-91.
Reynoldson JA, Behnke JM, Pallant LJ, Macnish MG, Gilbert F, Giles S, Spargo
RJ & Thompson RC (1997). Failure of pyrantel in treatment of human
51
Universitas Sumatera Utara
hookworm infections (Ancylostoma duodenale) in the Kimberley region of
North West Australia. Acta Trop. Halaman 68, 301-312.
Sanbayu, M.N.F. (2005) Efek Anthelmintik Ekstrak Air Kulit Buah Delima
(Punica granatum L.) Terhadap Cacing Gelang (Ascaris Lumbricoides
var. suum) Secara In Vitro dan In Vivo.Tesis. Universitas Surabaya.
Halaman 19.
Senja, R.Y., Issusilaningtyas, E., Nugroho, A.K., Setyowati, E.P. (2014). The
Comparison of Extraction Method and Solvent Variation on Yield and
Antioxidant Activity of Brassica oleracea L. Var capitata f. Rubra Extract.
Trad Med J. 19(1): 43-48.
Shahidi, F and M. Naczk. (1995). Food Phenolics. Technomic Inc, Basel.
Halaman 302.
Sharma, A., Gupta, S., Sachan, S., Mishra, A., Banarji, A. (2011). Anthelmintic
Activity of Leaf of Saraca indica Linn. As J Pharm Life Sci.1(4): 391395.
Sharma. S.K. (2010). Objective Zoology. India: KHRISHNA Prakash Media.
Halaman 2200-2261.
Shri, V.K., Senthamarai, R., Vasuki, K., Venkateswara, R.A., Selvadurai, S.
(2011). Anthelmintic Activity of Roots and Rhizomes of Corallocarpus
epigaeus. J Nat Prod Plant Resour . 1(1): 81-84.
Sitorus, P., Harahap, U., Pandapotan, M., dan Barus, T. (2014). Isolation Of βSitosterol From n-Hexane of Picria fel-terrae Lour. Leave and Study Of Its
Antidiabetic Effect in Alloxan Induced Diabetic Mice. International
Journal of PharmTech Research. 6(1): 137-141.
Soedarto. (2008). Parasitologi Klinik. Surabaya: Airlangga University Press.
Halaman 11.
Subash, K.R., Rao, N.J., Cheriyan, B.V., Bhaarati, G.M., Kumar, K. S. (2012).
The Antelmintic Activity of Eupatorium triplinerve and Alpinia galanga
in Pheretima posthuma and Ascardia galli: A Comparative Study. J Clin
Diag Res. 6(06): 947-950.
Sutherland, I.A., Leathwick, D.M. (2011). Anthelmintic Resistance in Nematode
Parasites of Cattle: A Global Issue? Trends Parasitol. Halaman 27, 176–
181.
Sykur, C. Dan Hernani. (2002). Budidaya Tanaman Obat Komersial. Penebar
Swadaya, Jakarta. Halaman 136.
Tekeshwar, K., Amit, A., Ajazuddin, Dhansay, D., Kushangra, N. (2011).
Anthelmintic Activity of the Whole Plant of Bauhinia purpurea (Linn.).
Asian Journal of Pharmaceutical and Clinical Research . 4(3): 110-111).
52
Universitas Sumatera Utara
Tiwow, D., Bodhi, W., dan Kojong, N.S. (2013). Uji Efek Antelmintik Ekstrak
Etanol Biji Pinang (Areca catechu)
Terhadap Cacing Ascaris
Lumbricoides dan Ascaridia Galii secara In Vitro. Pharmacon jurnal
ilmiah farmasi UNSRAT.2(2): 79-80.
Tjay, T.H., dan Rahardja, K. (2002). Obat Obat Penting Khasiat, Penggunaan
dan Efek-Efek Sampingnya . Edisi keempat. Jakarta.PT Elexmedia
komputindo kelompok gramedia. Halaman 196 – 205.
Tjahyanto, A. Dan Salim, C. (eds). (2013). Farmakologi Ulasan Bergambar .
Jakarta: EGC. Halaman 513-520.
Tjokropranoto, R., Rosnaeni, Nathania. M.Y. (2011). Anthelmintic Effect of
Ethanol Extract of Pare Leaf (Momordica charantia L.) Against Female
Ascaris suum Worm In Vitro, Jurnal Medika Planta . 1(4): 1334-1336.
Tyler , V.E. (1976). Pharmacognosy. Lea & Febiger, Philadelphia. Halaman 8789.
Urban, J., Kokoska, L., Langrova, I., and Matejkova, J. (2015). In Vitro
Anthelmintic Effects of Medicinal Plants Used in Czech Republic. 46(1011): 808-813.
Vennila V and Nivetha R. (2015). Screening The In vitro anthelmintic activity of
Alternanthera sessilis Leaves. Wrld J Pharm Pharm Sci. 4(04): 14021415.
Vercruysse, J., Behnke, J.M., Albonico, M., Ame, S.M., Angebault, C., Bethony,
J.M., Engels, D., Guillard, B., Hoa, N.T., Kang, G., Kattula, D., Kotze,
A.C., McCarthy, J.S., Mekonnen, Z., Montresor, A., Periago, M.V., Sumo,
L., Tchuem Tchuenté, L.A., Thach, D.T., Zeynudin, A., Levecke, B.
(2011). Assessment of The Anthelmintic Efficacy of Albendazole in
School Children in Seven Countries Where Soiltransmitted Helminths Are
Endemic. P Lo S Negl. Trop. Dis. Halaman 29, e948.
Vercruysse, J., Albonico, M., Behnke, J.M., Kotze, A.C., Prichard, R.K.,
McCarthy, J.S., Montresor, A., Levecke, B. (2011). Is Anthelmintic
Resistance a Concern For The Control of Human Soil-Transmitted
Helminths?. Int J Paras: Drug and Drug Resistance. 1(2011): 14-27.
Vincent, S., Vijayamirtharaj, R., Wilson, P., Saravanan, B., Jeevantham, R.,
Ramesh, R. (2011). Anthelmintic potential of Aerial Part of Clerodendrum
phlomidis Linn, Research Journal of Pharmaceutical, Biological and
Chemical Sciences. 2(2): 329-333.
Wang LS, Li SH, Zou JM, Guo YJ, Sun HD. (2006). Two New Terpenoids from
Picria fel-terrae. Journal of Asian Natural Product Research . 8(6): 491 494.
Wolstenholme, A.J., Fairweather, I., Prichard, R., von Samson-Himmelstjerna, G.,
Sangster, N.C. (2004). Drug resistance in veterinary helminths. Trends
Parasitol. Halaman 20, 469–476
53
Universitas Sumatera Utara
World Health Organization. (2015). Soil-Transmitted Helminth Infections.
[Diakses 18 Juli 2015]; diambil dari http://www.who.int/media
centre/factsheets/fs366/en/.
World Health Organization. (2011). Quality Control Methods For Medicinal
Plant Material. Switzherland: WHO. Halaman 19-25.
Wink, M. (2012). Medical plants: A Source of Anti Parasitic Secondary
Metabolites. Molecules. 17: 12771-12791.
Wynn, S.G., Fougere, B.J. (2007). Introduction: Why Use Herbal Medicine.
Dalam: Wynn, S.G., Fougere, B.J. (Ed). Veterinary Herbal Medicine:
Library of Congress Cataloging-in Publication Data . ISBN: 10:0-323029981.
Zhong, S.Q., Zhang, B.N., dan Huang, F.X. (1979). An Anti-Tumor Herb Cucao.
China: Chin Tradit Herb Drugs Lett 3 . Halaman 45–46.
Zou JM, Wang LS, Ma XM, Shi RB, Guo YJ. (2004). Isolation and Identification
of A New Cucurbitacin from Picria fel-terrae. Acta Pharmacutica Sinica .
39(11): 910-912.
Zou JM, Wang LS, Niu XM, Sun HD, Guo YJ. (2005). Phenylethanoid
Glycosides from Picria felterrae Lour. Journal of Integrative Plant
Biology. 47(5): 632-636.
Zulkoni, H. Akhsin. (2010). Parasitologi. Yogyakarta: Nuha Medika. Halaman
71-72.
54
Universitas Sumatera Utara