DAFTAR PUSTAKA Pemodelan Tiga Dimensi (3D) Ikatan Hasil Docking Molekular Turunan Diketopiperazin (DKP) Dengan Bcl-2 Pada Sel Mcf-7.
25
DAFTAR PUSTAKA
American Cancer Society. Breast Cancer. documents.cancer.org/104.00/104.
00.pdf (diakses tanggal 25 Juli 2012).
Amundson, S.A., Myers, T.G., Scudiero, D., Kitada, S., Reed, J.C., and
Fornace, A.J., 2000, An Informatics Approach Identifying Markers of
Chemosensitivity in Human Cancer Cell Lines, Cancer Res, 60, 61016110.
Andreani, A., Burnelli, S., Granaiola, M., Leoni, A.,Locatelli, A. & Morigi, R.
et al., 2008, Antitumor Activity of Bis-indole Derivates, J. Med.
Chem, 51, 4563-4570.
Annis, M.G., Soucie, E.L., Dlugosz, P.J., Cruz-Aguado, J.A., Penn, L.Z., &
Leber, B. et al., 2005, Bax forms multispanning monomers that
oligomerize to permeabilize membranes during apoptosis , EMBO J,
24, 2096-2103.
Anonim, 2008, Cell Biology, ATCC® Number: HTB-22TM, Designations:
MCF-7, http://www.atcc.org/ATCCAdvancedCatalogSearch/Product
Details/tabid/452/Default.aspx?ATCCNum=HTB22&Template=cellBi
ology (diakses pada tanggal 25 Juli 2012).
Anonim, 2010, MCF-7/GFP Cell Line, http://www.cellbiolabs.com/
sites/default/files/AKR-211-gfp-mcf-7-cell-line.pdf (diakses pada
tanggal 25 Juli 2012).
Aoki, T., Ohnishi, K., Kimoto, M., Fujieda, S., Kuramochi, K., & Takeuchi,
T. et al., 2010, Synthesis and Neuroprotective Action of Optically Pure
Neoechinulin A and Its Analogs, Pharmaceuticals, 3, 1063-1069.
Aouali, N., Morjani, H., Trussardi, A., Soma, E., Giroux, B., and Manfait, M.,
2003, Enhanced Cytotoxicity and Nuclear Accumulation of
Doxorubicin-loaded Nanospheres in Human Breast Cancer MCF-7
Cells Expressing MRP1, International Journal of Oncology, 23, 11951201.
Asiri, A.M., 2000, New Conjugated Systems Derived from Piperazine-2,5dione, Molecules, 5, 629-636.
Butt, A.J., Firth, S.M., King, M.A., and Baxter, R.C., 2000, Insulin-Like
Growth Factor-Binding Protein-3 Modulates Expression of Bax and
Bcl-2 and Potentiates P53-Independent Radiation-Induced Apoptosis
In Human Breast Cancer Cells, J. Biol Chem, 275 (50), 39174-39181.
26
Chan, M.M., Huang, H.I., Fenton, M.R., & Fong, D., 1998, In vivo inhibition
of nitric oxide synthase gene expression by curcumin, a cancer
preventive natural product with anti-inflammatory properties, Biochem
Pharmacol, 55, 1955–1962.
Dale, I.L., Tuffley, W., Callaghan, R., Holmes, J.A., Martin, K., & Luscombe,
M. et al., 1998, Reversal of P-glycoprotein-mediated multidrug
resistance by XR9051, a novel diketopiperazine derivative, British
Journal of Cancer, 78 (7), 885-892.
Deveau, A.M., Costa, N.E., Joshi, E.M., & Macdonald, T.L., 2008, Synthesis
of diketopiperazine-based carboline homodimers and in vitro growth
inhibition of human carcinomas, Bioorganic & Medicinal Chemistry
Letters, 18, 3522–3525.
Firozi, P.F., Aboobaker, V.S., & Bhattacharya, R.K., 1996, Action of
curcumin on the cytochrome P450-system catalyzing the activation of
aflatoxin B1, Chem-Biol Interact, 100, 41–51.
Fitria, M., Armandari, I., Septhea, DB., Ikawati, A.H.M., and Meiyanto, E.,
2011, Ekstrak etanolik Herba Ciplukan (Physalis angulata L.) Berefek
Sitotoksik dan Menginduksi Apoptosis pada Sel Kanker Payudara
MCF-7, Bionatura Jurnal Ilmu-Ilmu Hayati dan Fisik, 13 (2), 101107.
Graz, C.J.M., Grant, G.D., Brauns, S.C., Hunt, A., Jamie, H., & Milne, P.J.
Cyclic dipeptides in the induction of maturation for cancer therapy,
2000, http://onlinelibrary.wiley.com/doi/10.1211/0022357001773535/
abstract (diakses tanggal 8 Mei 2012).
Houston, D.R., Synstad, B., Eijsink, V.G.H., Stark, M.J.R., Eggleston, I.M., &
van Aalten,D.M.F., 2004, Structure-based exploration of cyclic
dipeptide chitinase inhibitors. J. Med. Chem., 47, 5713-5720.
Janssen, C.O., Lim, S., Lo, E.P., Wan, K.F.,Yu, V.C., Lee, M.A. et al., 2008,
Interaction of kendomycin and semi-synthetic analogues with the antiapoptotic protein Bcl-xl, Bioorganic & Medicinal Chemistry Letters,
18, 5771-5773.
Kaapro, A. dan Ojanen, J., 2002, Protein docking, http://www.lce.hut.fi/
teaching/S-114.500/k2002/Protdock (diakses tanggal 10 Mei 2012).
Kuo, M.L., Huang, T.S., & Lin, J.K., 1996, Curcumin, an antioxidant and antitumor promoter, induces apoptosis in human leukemia cells, Biochim
Biophys Acta, 1317, 95–100.
27
Lumongga, F., 2008, Apoptosis, Departemen Patologi Anatomi, Fakultas
Kedokteran, Universitas Sumatera Utara, Medan.
Marleen, F.S., Syahruddin, E., Hudoyo, A., Endarjo, S., Hidayat, H., &
Suzanna, E. et al., 2008, Ekspresi protein Bcl-2 pada sediaan blok
parafin jaringan kanker paru, Departemen Pulmonologi & Ilmu
Kedokteran Respirasi FKUI, Jakarta.
Menchetner, E., Kyshtoobayeva, A., Zonis, S., Kim, H., Stroup, R., Garcia,
R., Parker, R.J., and Fruehauf, J.P., 1998, Levels of Multidrug
Resistance (MDR1) P-Glycoprotein Expression by Human Breast
Cancer Correlate with in Vitro Resistance to Taxol and Doxorubicin,
Clinical Cancer Research, 4, 389-398.
Mooney, L.M., Al-Sakkaf, K.A, Brown, B.L., & Dobson, P.R.M., 2002,
Apoptotic Mechanisms in T47D and MCF-7 Human Breast Cancer
Cells, British Journal of Cancer, 87, 909 – 917.
National Cancer Institute. Breast Cancer.
http://www.cancer.gov/cancertopics/types/breast (diakses tanggal 25
Juli 2012).
Onuki, R., Kawasaki, H., Baba, T., dan Taira, K., 2003, Analysis of A
Mitochondrial Apoptotic Pathway Using Bid-Targeted Ribozymes in
Human MCF7 Cells in the Absence of A Caspase-3-Dependent
Pathway, Antisense and Nucleic Acid Drug Development, 13 (2), 7582.
Ovenden, S.P.B., Nielson, J.L., Liptrot C.H., Willis, R.H., Tapiolas, D.M., &
Wright A.D. et al, 2011, A New Diketopiperazine, Cyclo-(4-Shydroxy-R-proline- Risoleucine), from an Australian Specimen of the
Sponge Stelletta sp, Mar. Drugs, 9, 2469-2478.
Perkins, S., Verschoyle, R.D., Hill, K.A., & Parveen, I.,
2002,
Chemopreventive efficacy and pharmacokinetics of curcumin in the
Min/+ mouse, a model of familial adenomatous polyposis, Cancer
Epidem Biomar Prevent, 11, 535–540.
Petros, A.M., Huth, J.R., Oost, T., Park, C.M., Ding, H., & Wzng X. et al.,
2010, Discovery of potent and selective Bcl-2 inhibitor using SAR by
NMR, Bioorganic & Medicinal Chemistry Letters, 20, 6587-6591.
Porter, J., Payne, A., Candole, B., Ford, D., Hutchinson, B., & Trevitt, G., et
al., 2008, Tetrahydroisoquinoline amide substituedphenyl pyrazoles as
selective Bcl-2 inhibitors, Bioorganic & Medicinal Chemistry Letters,
19, 230-233.
28
Pranowo, H.D & Abdul, K.R.H., 2011, Pengantar Kimia Komputasi,
Bandung, Lubuk Agung.
Prunet, C., Lemaire-Ewing, S., Ménétrier, F., Néel, D., dan Lizard, G., 2005,
Activation of Caspase-3-Dependent and -Independent Pathways
During 7-Ketocholesterol- and 7β-Hydroxycholesterol-Induced Cell
Death: A Morphological and Biochemical Study, Journal of
Biochemical and Molecular Toxicology, 19 (5), 311-326.
Pyrkov, T.V., Priestle, J.P., Jacoby, E., & Efremov, R.G., 2008, Ligandspecific scoringfunctions: improved ranking of docking solutions,
http://www.ncbi.nlm.nih.gov/pubmed/18311637 (diakses tanggal 8
Mei 2012).
Shallal, H., Faridi, J.S., & Russu, W.A., 2011, Anti-tumor
pyrimidinylpiperazines bind to prosurvivalBcl-2 protein family
member Bcl-XL, Bioorganic & Medicinal Chemistry Letters, 21,
1325-1328.
Sharma, R.A., Harris, A.L., Dalgleish, A.G., Steward, W.P., & O’Byrne.,
2001, Angiogenesis as a biomarker and target in cancer
chemoprevention, Lancet Oncol, 2, 726–732.
Sharma, R.A., Gescher, A.J., & Steward, W.P., 2005, Curcumin: The story so
far, European Journal of Cancer, 41, 1955–1968.
Shina, R., Vidyarthi, A.S, & Shankaracharya, 2011, A molecular docking
study of anticancer drug paclitaxel and its analogues, Indian Journal of
Biochemistry and Biophisics, 48, 101-105.
Singh, S.V., Hu, X., Srivastava, S.K., Singh, M., Xia, H., & Orchard, J.L., et
al.., 1998, Mechanism of inhibition of benzoapyrene-induced
forestomach cancer in mice by dietary curcumin, Carcinogenesis, 19,
1357–1360.
Sumantran, V.N., Ealovega, M.W., Nunez, G., Clarke, M.F., & Wicha, M.S.,
1995, Overexpression of Bcl-xs Sensitizes MCF-7 Cells to
Chemotherapy-induced Apoptosis, Cancer Research, 55, 2507-2510.
Syaifudin, M., 2007, Gen Penekan Tumor p53, Kanker dan Radiasi Pengion,
Buletin Alara, 3 (8), 119 – 128.
Wilson, W.H., O’Connor, O.A., Czuczman, M.S., LaCasce, A.S., Gerecitano,
J.F., Leonard, J.P., et al., 2010, Navitoclax, a targeted high-affi nity
inhibitor of BCL-2, in lymphoidmalignancies: a phase 1 dose-
29
escalation study of safety, pharmacokinetics, pharmacodynamics, and
antitumour activity, Lancet Oncol, 11, 1149-1159.
Youle, R.J. & Stasser, A., 2008, The BCL-2 protein family: opposing
activities that mediate cell death, Nature Reviews, 9, 47-59.
Zampieri, L., Bianchi, P., Ruff, P., dan Arbuthnot, P., 2002, Differential
Modulation by Estradiol of P-glycoprotein Drug Resistance Protein
Expression in Cultured MCF7 and T47D Breast Cancer Cells,
Anticancer Res., 22 (4), 2253-9.
Zheng, C.H., Zhou, Y.J., Zhu, J., Ji, H.T., Chen, J. & Li, Y.W. et al., 2007,
Construction of three-dimensional pharmacophore for Bcl-2 inhibitors
by flexible docking and multiple copy simultaneous search method,
Bioorganic & Medicinal Chemistry, 15, 6407-6417.
DAFTAR PUSTAKA
American Cancer Society. Breast Cancer. documents.cancer.org/104.00/104.
00.pdf (diakses tanggal 25 Juli 2012).
Amundson, S.A., Myers, T.G., Scudiero, D., Kitada, S., Reed, J.C., and
Fornace, A.J., 2000, An Informatics Approach Identifying Markers of
Chemosensitivity in Human Cancer Cell Lines, Cancer Res, 60, 61016110.
Andreani, A., Burnelli, S., Granaiola, M., Leoni, A.,Locatelli, A. & Morigi, R.
et al., 2008, Antitumor Activity of Bis-indole Derivates, J. Med.
Chem, 51, 4563-4570.
Annis, M.G., Soucie, E.L., Dlugosz, P.J., Cruz-Aguado, J.A., Penn, L.Z., &
Leber, B. et al., 2005, Bax forms multispanning monomers that
oligomerize to permeabilize membranes during apoptosis , EMBO J,
24, 2096-2103.
Anonim, 2008, Cell Biology, ATCC® Number: HTB-22TM, Designations:
MCF-7, http://www.atcc.org/ATCCAdvancedCatalogSearch/Product
Details/tabid/452/Default.aspx?ATCCNum=HTB22&Template=cellBi
ology (diakses pada tanggal 25 Juli 2012).
Anonim, 2010, MCF-7/GFP Cell Line, http://www.cellbiolabs.com/
sites/default/files/AKR-211-gfp-mcf-7-cell-line.pdf (diakses pada
tanggal 25 Juli 2012).
Aoki, T., Ohnishi, K., Kimoto, M., Fujieda, S., Kuramochi, K., & Takeuchi,
T. et al., 2010, Synthesis and Neuroprotective Action of Optically Pure
Neoechinulin A and Its Analogs, Pharmaceuticals, 3, 1063-1069.
Aouali, N., Morjani, H., Trussardi, A., Soma, E., Giroux, B., and Manfait, M.,
2003, Enhanced Cytotoxicity and Nuclear Accumulation of
Doxorubicin-loaded Nanospheres in Human Breast Cancer MCF-7
Cells Expressing MRP1, International Journal of Oncology, 23, 11951201.
Asiri, A.M., 2000, New Conjugated Systems Derived from Piperazine-2,5dione, Molecules, 5, 629-636.
Butt, A.J., Firth, S.M., King, M.A., and Baxter, R.C., 2000, Insulin-Like
Growth Factor-Binding Protein-3 Modulates Expression of Bax and
Bcl-2 and Potentiates P53-Independent Radiation-Induced Apoptosis
In Human Breast Cancer Cells, J. Biol Chem, 275 (50), 39174-39181.
26
Chan, M.M., Huang, H.I., Fenton, M.R., & Fong, D., 1998, In vivo inhibition
of nitric oxide synthase gene expression by curcumin, a cancer
preventive natural product with anti-inflammatory properties, Biochem
Pharmacol, 55, 1955–1962.
Dale, I.L., Tuffley, W., Callaghan, R., Holmes, J.A., Martin, K., & Luscombe,
M. et al., 1998, Reversal of P-glycoprotein-mediated multidrug
resistance by XR9051, a novel diketopiperazine derivative, British
Journal of Cancer, 78 (7), 885-892.
Deveau, A.M., Costa, N.E., Joshi, E.M., & Macdonald, T.L., 2008, Synthesis
of diketopiperazine-based carboline homodimers and in vitro growth
inhibition of human carcinomas, Bioorganic & Medicinal Chemistry
Letters, 18, 3522–3525.
Firozi, P.F., Aboobaker, V.S., & Bhattacharya, R.K., 1996, Action of
curcumin on the cytochrome P450-system catalyzing the activation of
aflatoxin B1, Chem-Biol Interact, 100, 41–51.
Fitria, M., Armandari, I., Septhea, DB., Ikawati, A.H.M., and Meiyanto, E.,
2011, Ekstrak etanolik Herba Ciplukan (Physalis angulata L.) Berefek
Sitotoksik dan Menginduksi Apoptosis pada Sel Kanker Payudara
MCF-7, Bionatura Jurnal Ilmu-Ilmu Hayati dan Fisik, 13 (2), 101107.
Graz, C.J.M., Grant, G.D., Brauns, S.C., Hunt, A., Jamie, H., & Milne, P.J.
Cyclic dipeptides in the induction of maturation for cancer therapy,
2000, http://onlinelibrary.wiley.com/doi/10.1211/0022357001773535/
abstract (diakses tanggal 8 Mei 2012).
Houston, D.R., Synstad, B., Eijsink, V.G.H., Stark, M.J.R., Eggleston, I.M., &
van Aalten,D.M.F., 2004, Structure-based exploration of cyclic
dipeptide chitinase inhibitors. J. Med. Chem., 47, 5713-5720.
Janssen, C.O., Lim, S., Lo, E.P., Wan, K.F.,Yu, V.C., Lee, M.A. et al., 2008,
Interaction of kendomycin and semi-synthetic analogues with the antiapoptotic protein Bcl-xl, Bioorganic & Medicinal Chemistry Letters,
18, 5771-5773.
Kaapro, A. dan Ojanen, J., 2002, Protein docking, http://www.lce.hut.fi/
teaching/S-114.500/k2002/Protdock (diakses tanggal 10 Mei 2012).
Kuo, M.L., Huang, T.S., & Lin, J.K., 1996, Curcumin, an antioxidant and antitumor promoter, induces apoptosis in human leukemia cells, Biochim
Biophys Acta, 1317, 95–100.
27
Lumongga, F., 2008, Apoptosis, Departemen Patologi Anatomi, Fakultas
Kedokteran, Universitas Sumatera Utara, Medan.
Marleen, F.S., Syahruddin, E., Hudoyo, A., Endarjo, S., Hidayat, H., &
Suzanna, E. et al., 2008, Ekspresi protein Bcl-2 pada sediaan blok
parafin jaringan kanker paru, Departemen Pulmonologi & Ilmu
Kedokteran Respirasi FKUI, Jakarta.
Menchetner, E., Kyshtoobayeva, A., Zonis, S., Kim, H., Stroup, R., Garcia,
R., Parker, R.J., and Fruehauf, J.P., 1998, Levels of Multidrug
Resistance (MDR1) P-Glycoprotein Expression by Human Breast
Cancer Correlate with in Vitro Resistance to Taxol and Doxorubicin,
Clinical Cancer Research, 4, 389-398.
Mooney, L.M., Al-Sakkaf, K.A, Brown, B.L., & Dobson, P.R.M., 2002,
Apoptotic Mechanisms in T47D and MCF-7 Human Breast Cancer
Cells, British Journal of Cancer, 87, 909 – 917.
National Cancer Institute. Breast Cancer.
http://www.cancer.gov/cancertopics/types/breast (diakses tanggal 25
Juli 2012).
Onuki, R., Kawasaki, H., Baba, T., dan Taira, K., 2003, Analysis of A
Mitochondrial Apoptotic Pathway Using Bid-Targeted Ribozymes in
Human MCF7 Cells in the Absence of A Caspase-3-Dependent
Pathway, Antisense and Nucleic Acid Drug Development, 13 (2), 7582.
Ovenden, S.P.B., Nielson, J.L., Liptrot C.H., Willis, R.H., Tapiolas, D.M., &
Wright A.D. et al, 2011, A New Diketopiperazine, Cyclo-(4-Shydroxy-R-proline- Risoleucine), from an Australian Specimen of the
Sponge Stelletta sp, Mar. Drugs, 9, 2469-2478.
Perkins, S., Verschoyle, R.D., Hill, K.A., & Parveen, I.,
2002,
Chemopreventive efficacy and pharmacokinetics of curcumin in the
Min/+ mouse, a model of familial adenomatous polyposis, Cancer
Epidem Biomar Prevent, 11, 535–540.
Petros, A.M., Huth, J.R., Oost, T., Park, C.M., Ding, H., & Wzng X. et al.,
2010, Discovery of potent and selective Bcl-2 inhibitor using SAR by
NMR, Bioorganic & Medicinal Chemistry Letters, 20, 6587-6591.
Porter, J., Payne, A., Candole, B., Ford, D., Hutchinson, B., & Trevitt, G., et
al., 2008, Tetrahydroisoquinoline amide substituedphenyl pyrazoles as
selective Bcl-2 inhibitors, Bioorganic & Medicinal Chemistry Letters,
19, 230-233.
28
Pranowo, H.D & Abdul, K.R.H., 2011, Pengantar Kimia Komputasi,
Bandung, Lubuk Agung.
Prunet, C., Lemaire-Ewing, S., Ménétrier, F., Néel, D., dan Lizard, G., 2005,
Activation of Caspase-3-Dependent and -Independent Pathways
During 7-Ketocholesterol- and 7β-Hydroxycholesterol-Induced Cell
Death: A Morphological and Biochemical Study, Journal of
Biochemical and Molecular Toxicology, 19 (5), 311-326.
Pyrkov, T.V., Priestle, J.P., Jacoby, E., & Efremov, R.G., 2008, Ligandspecific scoringfunctions: improved ranking of docking solutions,
http://www.ncbi.nlm.nih.gov/pubmed/18311637 (diakses tanggal 8
Mei 2012).
Shallal, H., Faridi, J.S., & Russu, W.A., 2011, Anti-tumor
pyrimidinylpiperazines bind to prosurvivalBcl-2 protein family
member Bcl-XL, Bioorganic & Medicinal Chemistry Letters, 21,
1325-1328.
Sharma, R.A., Harris, A.L., Dalgleish, A.G., Steward, W.P., & O’Byrne.,
2001, Angiogenesis as a biomarker and target in cancer
chemoprevention, Lancet Oncol, 2, 726–732.
Sharma, R.A., Gescher, A.J., & Steward, W.P., 2005, Curcumin: The story so
far, European Journal of Cancer, 41, 1955–1968.
Shina, R., Vidyarthi, A.S, & Shankaracharya, 2011, A molecular docking
study of anticancer drug paclitaxel and its analogues, Indian Journal of
Biochemistry and Biophisics, 48, 101-105.
Singh, S.V., Hu, X., Srivastava, S.K., Singh, M., Xia, H., & Orchard, J.L., et
al.., 1998, Mechanism of inhibition of benzoapyrene-induced
forestomach cancer in mice by dietary curcumin, Carcinogenesis, 19,
1357–1360.
Sumantran, V.N., Ealovega, M.W., Nunez, G., Clarke, M.F., & Wicha, M.S.,
1995, Overexpression of Bcl-xs Sensitizes MCF-7 Cells to
Chemotherapy-induced Apoptosis, Cancer Research, 55, 2507-2510.
Syaifudin, M., 2007, Gen Penekan Tumor p53, Kanker dan Radiasi Pengion,
Buletin Alara, 3 (8), 119 – 128.
Wilson, W.H., O’Connor, O.A., Czuczman, M.S., LaCasce, A.S., Gerecitano,
J.F., Leonard, J.P., et al., 2010, Navitoclax, a targeted high-affi nity
inhibitor of BCL-2, in lymphoidmalignancies: a phase 1 dose-
29
escalation study of safety, pharmacokinetics, pharmacodynamics, and
antitumour activity, Lancet Oncol, 11, 1149-1159.
Youle, R.J. & Stasser, A., 2008, The BCL-2 protein family: opposing
activities that mediate cell death, Nature Reviews, 9, 47-59.
Zampieri, L., Bianchi, P., Ruff, P., dan Arbuthnot, P., 2002, Differential
Modulation by Estradiol of P-glycoprotein Drug Resistance Protein
Expression in Cultured MCF7 and T47D Breast Cancer Cells,
Anticancer Res., 22 (4), 2253-9.
Zheng, C.H., Zhou, Y.J., Zhu, J., Ji, H.T., Chen, J. & Li, Y.W. et al., 2007,
Construction of three-dimensional pharmacophore for Bcl-2 inhibitors
by flexible docking and multiple copy simultaneous search method,
Bioorganic & Medicinal Chemistry, 15, 6407-6417.