KINETICS OF ANTI CANINE PARVOVIRUS IgY IN DOGS.

THE 6.,'
lNTERNATIONAL CONI,ER FNCF
OIIV I]IOSC,]ENCE AND BIOTECHNOI OGY
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THE 6th
INTERNATIONAL CONFERENCE ON

BIOSCIENCE AND BIOTECHNOLOGY
"Bioscietrce & Biotcchnology for Maintairing Wortd prosperi(y,

BOOK OF ABSTRACT

B.li INDONtrSrA.18 - t9

Sept€mber 2015

PROGRAM
|EE €\ ]NIEXNINONAL

CONFERENCE ON BNS1ENCE AXD

R IOTECENOIOG|

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Kin€tics of Anti Corire

?anolils

IgY in Dogs


A A Sudinti, s ldra(atiL, N L.p Asuiinir, A suprarcsi.
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tnreml t\ledicine, Fmtty ot vcrc.in:ry Medicine.
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Ab*ract
KDcric iudyorAnti CPv IgY h6 befl perfomed on ex dogs aeed 1-5 monrhr. The
leY s.s inlekd mtaveDnsly rhcdoseol2t,l mgr lokgtodyweigtu. Igy levek

tri rl'. blood

Hs ddemined by ELISA


The kinetics of lgYdissemrndnJn was
caLcnlrtd byrlgr.sio. aMl)ris to d.r.dine the ElatioNhip bel*een dre lerek ot
lgYii se'lna$sr rine at injection Kincrc palmerec Nere .atcutaGd hNd on

Itr*ord ki'r.ric. TheresulrsshosedrhrthccoslanielininalonftreotlgYwas{

0r5 /h) (0.0t1a 0.001/ h) tqy co.scnrabon in ihe btood
ordoss eas a hc mnse (0.?46 ro 0 ee2 ms / mD (0 95 + 0 009 h!/ mt). The har lite
oosYin blood $as d rhc ranse (3960 to 96.25 / h) (60 t0 + 13.96 / ho t lgy
volune distributionr'6 ar rhe ranle &on {21,17 to 23.55 / nt)(22.72 + ? 6t I mt)
TohlIgY m the b.dies dog (AUC) *as at ft from (4260 r. 11200 mS / hl.lam)
(3,1.79 = ll 23 niB / mtjafr). The dumiion of$e lgy in the dogs bod) las ar dr
ranSe from (7133 b 204 3 hou6)(130 7l1al.3a houi!).leY ckaraDce line *as ai
thc mige lrom (0 Ii ro 0.50 nl/ h) (0 29 + 0 lt nlr h). In conctusjon the kincljcs ot
uri cf\i rgY iD d.3 s bodJr toltou one compdhe .nd fiEt o.d nodcl. onty
diribuled in rhe brood, sith lhe h'lflife ar 25 dal , md IgY posibiLly to
rccunuhle in rhe bodr is smalle. nhln lhose ol IgG.
Ihe nnge from (0 007 ro 0

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