PREFACE LIST OF CONTENT PLANNERS AND LECTURERS TEAM FACILITATORS

Pharmacology is simply defined as the study of drugs. Pharmacology can also be defined as the study of substances that interact with living systems through chemical processes, especially by binding to regulatory molecules and activating or inhibiting normal body processes. These substances are generally known as drugs. Drugs as we know including any substances that bring about a change in biologic function through its chemical actions or produce effect on living organism. According to definition from the Indonesian Ministry of Health, drugs included not only any substances that used for treating diseases, but also substances for preventing diseases and for confirming diagnosis of such diseases. These substances commonly produce more than one effect, it can be beneficial therapeutic effects or, in the other hand, undesirable effects on living systems adverse or toxic effects. All substances drugs can be toxic under certain circumstances. Pharmacology refers to a very broad area of study. Pharmacokinetics and pharmacodynamics are two basic subject area of pharmacology. Pharmacokinetics concern about the actions of the body on drug or the fate of drug in our body, including absorption, distribution, metabolism, and elimination; whereas pharmacodynamics concern about the action of drug in our body, including receptor interaction, as well as mechanism of therapeutic and toxic action. In this block, we will learn about the basic concept of pharmacology, including drug development and regulation, drug category, drug pharmacokinetics, drug pharmacodynamics, drug interaction, adverse drug effects, and rational drug use, as well as some basic concepts of several important drugs including drugs act on autonomic nervous system, antibiotics and analgesic antiinflammation. This block will take 10 meeting to be completed, each meeting consist of introductory lecture continued by independent learning, small group discussion SGD, ending with plenary session. In each topic there will be a list of tasks to discuss on SGD which some of them are based on a case that commonly find in clinical practice. There will also a student project assignment that should be fulfilled by all students in group. Each group will be given one topic for student project and this has to be presented at the end of block based on schedule. There will be also practical session related to basic pharmacology. Evaluation in this block will be formative and summative. The formative evaluation is directive and will take as checklist and peer assessment, while summative will be conducted at the end of this block. We believe that the basic of pharmacology that you will learn in this block will impulse you to learn more about it to help you managing patients in your next clinical practice. Good luck, Planner team Udayana University Faculty of Medicine, DME, 2016 1

1. PREFACE

No List Page no. 1. Cover 2. Preface 1 3. List of Content 2 4. Planners and Lecturers Team 3 5. Facilitators 4 6. Curriculum Block: Basic Pharmacology 5 7. Time Table 6 8. Meeting of Student Representatives 8 9. Student Project 8 10. Assessment Method 9 11. References 9 12. Content Outline and Learning Task 10 13. Guideline for Practical Session 17 14. Curriculum Map 22 PLANNERS AND LECTURERS No. NAME DEPARTEMENT PHONE 1. dr. I Gusti Ayu Artini, M.Sc. Head Pharmacology 08123650481 2. Desak Ketut Ernawati, S.Si, Apt, M.Pharm. Secretary Pharmacology 081236753646 3. dr. Agung Nova Mahendra, M.Sc. Pharmacology 087861030195 4. Prof. dr. IGM Aman, SpFK Pharmacology 081338770650 5. Dr. dr. I Made Jawi, M.Kes. Pharmacology 08179787972 Udayana University Faculty of Medicine, DME, 2016 2

2. LIST OF CONTENT

3. PLANNERS AND LECTURERS TEAM

6. Dr. dr. BK Satriyasa, M.Repro Pharmacology 081237166686 7. dr. Ida Bagus Ngurah, M.FOr Pharmacology 08123687288 REGULAR CLASS NO NAME GROUP DEPT PHONE ROOM 1 Dr.dr. I Made Jawi, M.Kes A1 Pharmacology 08179787972 2 nd floor: R.2.01 2 dr. Ni Ketut Putri Ariani, Sp.KJ A2 Psychiatry 082237817384 2 nd floor: R.2.02 3 dr. IGA Ratnayanti, M.Biomed A3 Histology 085104550344 2 nd floor: R.2.03 4 dr. I B Darma Putra, Sp.B- KBD A4 Surgery 08123600552 2 nd floor: R.2.04 5 dr. I Gde Haryo Ganesha, S.Ked A5 DME 081805391039 2 nd floor: R.2.05 6 dr. Gusti Ngurah Mayun, Sp.HK A6 Histology 08155715359 2 nd floor: R.2.06 7 dr. I Ketut Wibawa Nada, Sp.An A7 Anasthesi 087860602995 2 nd floor: R.2.07 8 dr. I Wayan Weta, MS, Sp.GK A8 Public Health 081337003560 2 nd floor: R.2.08 9 dr. Muliani, M.Biomed A9 Anatomy 085103043575 2 nd floor: R.2.21 10 dr. Putu Patriawan, Sp.Rad, A10 Radiology 08123956636 2 nd floor: Udayana University Faculty of Medicine, DME, 2016 3

4. FACILITATORS

MSc R.2.22 ENGLISH CLASS NO NAME GROUP DEPT PHONE ROOM 1 dr. I Wayan Surudarma, M.Si B1 Biochemistry 081338486589 2 nd floor: R.2.01 2 dr. I Wayan Losen Adnyana, Sp PD B2 Interna 08123995536 2 nd floor: R.2.02 3 Dr. dr. Sianny Herawati, Sp.PK B3 Clinical Pathology 081236172840 2 nd floor: R.2.03 4 dr. Yuliana, M.Biomed B4 Anatomy 085792652363 2 nd floor: R.2.04 5 dr. Made Agus Hendrayana , M.Ked B5 Microbiology 08123921590 2 nd floor: R.2.05 6 dr. I Nyoman Semadi, Sp.B, Sp.BTKV B6 Surgery 08123838654 2 nd floor: R.2.06 7 dr. I Wayan Eka Sutyawan, Sp.M B7 Opthalmology 081338538499 2 nd floor: R.2.07 8 dr. Kadek Budi Santosa, Sp.U B8 Surgery 081339977799 2 nd floor: R.2.08 9 dr. Sri Laksminingsih Sp. Rad B9 Radiology 08164745561 2 nd floor: R.2.21 10 dr. I Gede Suwedagatha, Sp.B K Trauma B10 Surgery 0811387720 2 nd floor: R.2.22 LEARNING OUTCOME 1. Comprehend the basic concept of pharmacology including concept of drug pharmacokinetics and pharmacodynamics. 2. Comprehend the process of drug development. 3. Comprehend the principle of drug interaction. 4. Comprehend the principle of rational drug use. 5. Comprehend the basic concept of pharmacology for some drugs used in many system disorders autonomic drugs, antibiotics and analgesics antiinflammation. LEARNING OBJECTIVE 1. Describe the concept of drug pharmacokinetics. 2. Describe the concept of drug pharmacodynamics. 3. Define the process of drug development. 4. Identify the classification of drug. 5. Define the principle of drug interaction. 6. Define the principle of rational drug use. 7. Describe the concept of pharmacology for autonomic drugs. 8. Describe the concept of pharmacology for antibiotics. 9. Describe the concept of pharmacology for analgesics antiinflammation. LEARNING STRATEGY : Udayana University Faculty of Medicine, DME, 2016 4

5. CURRICULUM BLOCK: BASIC PHARMACOLOGY