ASSESSMENT METHOD REFERENCES Study guide blok farmakologi sem II 28 maret 2016

Abbas AK, Lichtman AH, Pober JS. 2011. Cellular and Molecular Immunology. 4 th ed. Pennysylvania: WB Saunders Co. Pp 1636-1642. Assessment in this block consists of: SGD : 5 Final Exam : 80 Student Project : 15 Total result will contribute as much as 40 to overall score of Medical Communication Block Final exam will be carried out at the end of block using Multiple Choice Questions MCQ type. The minimal passing score for the assessment is 70. Every student should pass the minimum passing score for both Medical Communication and Basic Pharmacology Block. The requirement for taking the final exam: - join 75 of total student activities - bring student ID card with photo 1. Katzung BG, Masters SB, Trevor AJ. 2012. Basic and Clinical Pharmacology. 12 th ed. New York: McGraw Hill. 2. Trevor AJ, Katzung BG, Masters SB. 2005. Pharmacology Examination and Board Review. 7 th ed. New York: McGraw Hill. 3. Brunton LL and Parker KL. 2008. Goodman and Gilman’s Manual of Pharmacology and Therapeutics. New York: McGraw Hill. 4. Lullman H, Mohr K, Hein L, Bieger D. 2005. Color Atlas of Pharmacology. 3 rd ed. New York: Thieme Stutgart. 5. Hitner H and Nagle B. 2002. Glencoe Basic Pharmacology. 4 th ed. New York: McGraw Hill. Udayana University Faculty of Medicine, DME, 2016 9

9. ASSESSMENT METHOD

10. REFERENCES

Pharmacology is defined as the study of substances that interact with living systems through chemical processes, especially by binding to regulatory molecules and activating or inhibiting normal body processes. These substances commonly known as drugs. Drugs might produce more than one effect, beneficial therapeutic effects or, in the other hand, undesirable effects on living systems adverse or toxic effects. Pharmacology refers to a very broad area of study. Pharmacokinetics and pharmacodynamics are two basic subject area of pharmacology. There are several sources of drugs, including plant, animal, microorganism and chemical synthesis. Drug candidates undergo several tests for screening their pharmacologic profile and activity as well as their selectivity. The safety and efficacy of drugs must be defined before they can be marketed; therefore some preclinical pharmacologic and toxicity testing including invitro and animal studies, as well as clinical study phase 1 – 4 must be performed. Many factors affecting the action of drug in our body including the route of drug administration which is related to drug preparation or drug form, age, sex, weight, genetic variation, the presence of other disease or interaction with other drug drug interaction. Drug interaction refers to the effects that occur when the actions of one drug are affected by another drug. Drug interaction might affect the pharmacokinetic or pharmacodynamics process of drug that subsequently affects the drug action or effect. Related to the regulation of drug distribution in Indonesia, Indonesian Ministry of Health has already classified marketed drugs into five groups of drugs free drug, limited free drug, hard drug, psychotropic drug and narcotics. Generally, in the world, drugs are divided into prescription and nonprescription drugs over the counter drugs OTC drugs. Drugs can also be classified into patent drugs, generic drugs and branded generic drugs. Vignete A 25 years old woman came to public health center PHC complaining fever since 3 days ago. Patients also complained sore throat, cough, cold and headache. After doing anamnesis and physical examination, doctor decided to prescribe Demacolin® and Amoxsan® tablet. Learning Task 1 1. What are the categories of those two drugs? 2. What are the advantages and disadvantages of this route of administration? 3. What processes undergone by such oral drug in our body? Learning Task 2 A few hours later, patient came back to PHC complaining rash and itchy in her whole body. 1. What condition possibly happened to this patient? 2. What information should be given to the patient related to her condition? Udayana University Faculty of Medicine, DME, 2016 10

11. CONTENT OUTLINE AND LEARNING TASK