Crude Palm Oil Consumption Was Accepted and Improved Lipid Profile and Reduced C Reactive Protein Content in Plasma of Childbearing Age Women In Sub District Dramaga Bogor
KONSUMSI MINYAK SAWIT MENTAH (MSMn) DAPAT DITERIMA
DAN MEMPERBAIKI PROFIL LIPID SERTA MENURUNKAN KADAR
C-REACTIVE PROTEIN (C-RP) PLASMA IBU USIA PRODUKTIF
DI KECAMATAN DRAMAGA KABUPATEN BOGOR
NURSALIM
SEKOLAH PASCASARJANA
INSTITUT PERTANIAN BOGOR
BOGOR
2012
PERNYATAAN MENGENAI TESIS
DAN SUMBER INFORMASI
Dengan ini saya menyatakan bahwa tesis berjudul Konsumsi Minyak
Sawit Mentah (MSMn) Dapat Diterima dan Memperbaiki Profil Lipid serta
Menurunakan Kadar C-Reactive Protein (C-RP) Ibu Usia Produktif di Kecamatan
Dramaga Kabupaten Bogor adalah karya saya dengan arahan dari komisi
pembimbing dan belum diajukan dalam bentuk apapun kepada perguruan tinggi
manapun. Sumber informasi yang berasal atau dikutip dari karya yang diterbitkan
dari penulis lain telah disebutkan dalam teks dan dicantumkan dalam Daftar
Pustaka di bagian akhir tesis ini.
Bogor Juni 2012
Nursalim
F 251100261
ABSTRACT
NURSALIM. Crude Palm Oil Consumption Was Accepted and Improved Lipid
Profile and Reduced C-Reactive Protein Content in Plasma of Childbearing Age
Women In Sub District Dramaga Bogor. Under direction of ENDANG
PRANGDIMURTI and FRANSISKA RUNGKAT- ZAKARIA .
Crude palm oil (CPO) contains carotenoids, including beta carotene around
400-1000 ppm as provitamin A and vitamin E (tocopherol and tocotrienol)
around 559-1000 ppm. Fatty acid composition of red palm oil consists of 50%
saturated fatty acids and 50% unsaturated fatty acids. Unsaturated fatty acids in
red palm oil can up regulate LDL cholesterol receptors there by increasing
catabolism of LDL cholesterol. Tocotrienols in palm oil can inhibit 3-hydroxy-3methylglutaryl coenzyme A (HMG-CoA) reductase in cholesterol biosynthetic
pathway. Beta carotene and vitamin E in red palm oil are powerful antioxidant
against free radicals. C-reactive protein (C-RP) is a marker of inflammation, the
antioxidants in red palm oil can reduce the incidence of inflammation. The
purpose of this study was to determine the acceptance of CPO as cooking oil and
the effect of its consumption on lipid profile and C-reactive protein. Subjects total
of 151 families, including 508 respondents were given 140 ml CPO in plastic
bottle weekly for 2 months freely. The distribution was accompanied with
socialization of oil benefit and utilization with five types of questionnaires. For
plasma analysis, blood from 33 mothers of childbearing age were withdrawn
before and after oil distribution and analyzed for C-reactive protein and lipid
profile. The oil was accepted by the respondent and used as cooking oil. The
results showed that consumption of red palm oil reduce absorbance levels of CRP from 0,111 to 0,103, total cholesterol from 168,3 mg/dL to 158,0 mg/dL, LDL
cholesterol from 98,7 mg/dL to 81,1 mg/dL, ratio total cholesterol:HDL from 4,3
to 3,5 and increase HDL cholesterol from 41,5 mg/dL to 45,6 mg/dL was
significantly (p
DAN MEMPERBAIKI PROFIL LIPID SERTA MENURUNKAN KADAR
C-REACTIVE PROTEIN (C-RP) PLASMA IBU USIA PRODUKTIF
DI KECAMATAN DRAMAGA KABUPATEN BOGOR
NURSALIM
SEKOLAH PASCASARJANA
INSTITUT PERTANIAN BOGOR
BOGOR
2012
PERNYATAAN MENGENAI TESIS
DAN SUMBER INFORMASI
Dengan ini saya menyatakan bahwa tesis berjudul Konsumsi Minyak
Sawit Mentah (MSMn) Dapat Diterima dan Memperbaiki Profil Lipid serta
Menurunakan Kadar C-Reactive Protein (C-RP) Ibu Usia Produktif di Kecamatan
Dramaga Kabupaten Bogor adalah karya saya dengan arahan dari komisi
pembimbing dan belum diajukan dalam bentuk apapun kepada perguruan tinggi
manapun. Sumber informasi yang berasal atau dikutip dari karya yang diterbitkan
dari penulis lain telah disebutkan dalam teks dan dicantumkan dalam Daftar
Pustaka di bagian akhir tesis ini.
Bogor Juni 2012
Nursalim
F 251100261
ABSTRACT
NURSALIM. Crude Palm Oil Consumption Was Accepted and Improved Lipid
Profile and Reduced C-Reactive Protein Content in Plasma of Childbearing Age
Women In Sub District Dramaga Bogor. Under direction of ENDANG
PRANGDIMURTI and FRANSISKA RUNGKAT- ZAKARIA .
Crude palm oil (CPO) contains carotenoids, including beta carotene around
400-1000 ppm as provitamin A and vitamin E (tocopherol and tocotrienol)
around 559-1000 ppm. Fatty acid composition of red palm oil consists of 50%
saturated fatty acids and 50% unsaturated fatty acids. Unsaturated fatty acids in
red palm oil can up regulate LDL cholesterol receptors there by increasing
catabolism of LDL cholesterol. Tocotrienols in palm oil can inhibit 3-hydroxy-3methylglutaryl coenzyme A (HMG-CoA) reductase in cholesterol biosynthetic
pathway. Beta carotene and vitamin E in red palm oil are powerful antioxidant
against free radicals. C-reactive protein (C-RP) is a marker of inflammation, the
antioxidants in red palm oil can reduce the incidence of inflammation. The
purpose of this study was to determine the acceptance of CPO as cooking oil and
the effect of its consumption on lipid profile and C-reactive protein. Subjects total
of 151 families, including 508 respondents were given 140 ml CPO in plastic
bottle weekly for 2 months freely. The distribution was accompanied with
socialization of oil benefit and utilization with five types of questionnaires. For
plasma analysis, blood from 33 mothers of childbearing age were withdrawn
before and after oil distribution and analyzed for C-reactive protein and lipid
profile. The oil was accepted by the respondent and used as cooking oil. The
results showed that consumption of red palm oil reduce absorbance levels of CRP from 0,111 to 0,103, total cholesterol from 168,3 mg/dL to 158,0 mg/dL, LDL
cholesterol from 98,7 mg/dL to 81,1 mg/dL, ratio total cholesterol:HDL from 4,3
to 3,5 and increase HDL cholesterol from 41,5 mg/dL to 45,6 mg/dL was
significantly (p