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Changes of Ureum-Creatinin Level in Acute Stroke Patients Treated with Mannitol in Department of Neurology, Medical Faculty University of Sumatera Utara Haji Adam Malik Hospital Medan – Indonesia

Changes of Ureum-Creatinin Level in Acute Stroke Patients Treated with
Mannitol in Department of Neurology, Medical Faculty University of
Sumatera Utara Haji Adam Malik Hospital Medan – Indonesia
Dalton Silaban, Rusli Dhanu, dan Darulkutni Nasution
Department of Neurology, Medical School,
University of Sumatera Utara/H. Adam Malik Hospital, Medan, Indonesia

nd

day, and on the
5th day after administration. Result: of 25 patients (16 males, 9 females); 9 patients had acute
ischemic stroke and 16 had acute hemorrhage stroke. Increasing of serum ureum level 1,40 times
was observed on the 2nd day (p< 0.05) and 2.01 times on the 5th day (p< 0.05) and serum creatinin
level was increased 1.32 times on the 2nd day (p< 0.05) and 1.85 times on the 5th day (p < 0.05)
compared with the value before administration. Conclusion: mannitol 20% administration for
acute stroke patients with increased intracranial pressure showed increasing of serum ureumcreatinin level significantly (p

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