PRELIMINARY REPORT: APRIL 2009 - AUGUST 2010 National Infl ammatory Arthritis Registry NIAR
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3. CHARACTERISTICS OF PATIENTS
3.1 NUMBER OF PATIENTS FULFILLING AMERICAN COLLEGE OF RHEUMATOLOGY ACR CRITERIA
The tradi onal defi ni on for Rheumatoid Arthri s has been defi ned as pa ents fulfi lling 4 or more of the 7 criteria listed in the 1987 ACR criteria Table 2 3.
This criteria has been revised in the new ACR-EULAR criteria published in 2010 4.
Morning s ff ness 1 hour
≥ 3 joints arthri s Arthri s in a wrist, MCP or PIP joint
Symmetrical arthri s Factor
Posi ve rheumatoid factor Erosions or osteopenia on hand or wrist radiograph
symptoms present for at least 6 weeks
Table 2: 1987 ACR criteria for Rheumatoid Arthri s
The propor on of pa ents fulfi lling each criterion is shown in Table 3. ACR criteria
of pa ents fulfi lling criteria ≥ 3 joints arthri s
94.4 Symmetrical arthri s
92.8 Arthri s in a wrist, MCP or PIP joint
70.5 Morning s
ff ness 1 hour 70.5
Posi ve rheumatoid factor 68.5
Erosions or osteopaenia on hand or wrist radiograph
41.0 Rheumatoid factor
6.1 Table 3: Percentage of pa ents fulfi lling each ACR criteria
PRELIMINARY REPORT: APRIL 2009 - AUGUST 2010 National Infl ammatory Arthritis Registry NIAR
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The percentage of pa ents fulfi lling the 1987 ACR criteria is shown in Figure 9. 78.3 fulfi ll the ACR criteria defi ni on for Rheumatoid Arthri s however a
signifi cant propor on fulfi ll less than 4 of the criteria.
5 10
15 20
25 30
35
4 22.5
34
1.8 20
5 6
7
21.7
78.3
≥ 4 ≥ 4
o f
p a
e n
ts
Number of ACR Criteria fulfi lled
Figure 9: Percentage of pa ents fulfi lling ACR criteria
3.2 DURATION OF DISEASE BEFORE DIAGNOSIS
Almost half of the pa ents were diagnosed late, that is more than a year a er the onset of symptoms. However, a signifi cant propor on of pa ents were
diagnosed between 1 to 6 months from symptom onset.
10 20
30 40
50
37.3
6 months 6 months
12 months
14 48.7
Number of months from symptom onset to diagnosis Figure 10: Distribu on of pa ents according to dura on of disease
before diagnosis