Pengaruh Pemberian Vitamin D Terhadap Perbaikan Foto Toraks Pada Pasien TB Paru Etnik Batak Di Kota Medan Dihubungkan Dengan Polimorfisme ApaI Gen Reseptor Vitamin D
106
LAMPIRAN
Universitas Sumatera Utara
107
LAMPIRAN DOKUMEN PENELITIAN
Gmbr 1. Isolasi DNA
Gambar 4. KIT Vitamin D
Gambar 2. RFLP
Gambar 5. KIT Vitamin D
Universitas Sumatera Utara
108
Gambar 7. Penomoran sampel
Gambar 6. Persiapan RFLP
Gambar 8: Kit Vitamin D
Gambar 9 Buffer
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109
Gambar10. Meemberikan vitamin D ke sampel
Gambar 11. Sampel Minum Vitamin D
Gambar: PCR
Gambar : Hasil RFLP Polimorfisme
Gambar: RFLP Polimorfisme Apa1
Universitas Sumatera Utara
110
LAMPIRAN : PENGOLAHAN DATA BERDASARKAN SPSS
1. KARAKTERISTIK RESPONDEN
Umur Responden Kelompok Vitamin D
Frequency
Percent
Valid Percent
Valid
1
2
11
9
52.4
42.9
52.4
42.9
3
Total
1
21
4.8
100.0
4.8
100.0
Cumulative
Percent
52.4
95.2
100.0
Statistics
Umur Responden Kelompok Vitamin D
N
Valid
Missing
21
0
34.00
31.00
12.128
Mean
Median
Std. Deviation
Umur Responden Kelompok Plasebo
Frequency
Percent
Valid Percent
18-34
35-52
Valid
53-69
4
9
8
19.0
42.9
38.1
19.0
42.9
38.1
Total
21
100.0
100.0
Statistics
Umur Responden Kelompok Plasebo
Valid
N
Missing
Mean
Median
Std. Deviation
Cumulative
Percent
19.0
61.9
100.0
21
0
46.19
49.00
14.500
Universitas Sumatera Utara
111
Jenis kelamin responden Kelompok Vitamin D
Frequency
Percent
Valid Percent
laki-laki
Valid perempuan
Total
13
8
21
61.9
38.1
100.0
Cumulative
Percent
61.9
61.9
38.1
100.0
100.0
Jenis Kelamin Responden Kelompok Plasebo
Frequency
Percent
Valid Percent
Cumulative
Percent
laki-laki
Valid
perempuan
Total
13
61.9
61.9
61.9
8
38.1
38.1
100.0
21
100.0
100.0
Pekerjaan Responden Kelompok Vitamin D
Frequency
mahasiswa
bekerja
Valid tidak
bekerja
Total
Percent
Valid Percent
3
13
14.3
61.9
14.3
61.9
Cumulative
Percent
14.3
76.2
5
23.8
23.8
100.0
21
100.0
100.0
Pekerjaan Responden Kelompok Plasebo
Frequency
Percent
Valid Percent
Cumulative
Percent
mahasiswa
bekerja
1
4.8
4.8
4.8
13
61.9
61.9
66.7
7
33.3
33.3
100.0
21
100.0
100.0
Valid
tidak bekerja
Total
Universitas Sumatera Utara
112
2. STATUS VITAMIN D
Kadar Vitamin D Sebelum intervensi Pada Kelompok Vitamin D
Frequency
Percent
Valid Percent
Cumulative
Percent
Defisiensi
3
14.3
14.3
14.3
insufisiensi
6
28.6
28.6
42.9
Valid
optimal
12
57.1
57.1
100.0
Total
21
100.0
100.0
Kadar Vitamin D Sebelum Intervensi Kelompok Plasebo
Frequency
Percent
Valid Percent
Cumulative
Percent
Defisiensi
2
9.5
9.5
9.5
insufisiensi
8
38.1
38.1
47.6
Valid
optimal
11
52.4
52.4
100.0
Total
21
100.0
100.0
3. KADAR VITAMIN D PADA KELOMPOK YANG DIBERIKAN VITAMIN D
Descriptives Kadar Vitamin D
Statistic
Mean
31.3524
95% Confidence Interval for
Lower Bound
27.1875
Mean
Upper Bound
35.5173
5% Trimmed Mean
31.4721
Median
32.6700
kadar vitamin d sebelum
Variance
intervensi
Std. Deviation
Std. Error
1.99664
83.718
9.14977
Minimum
13.26
Maximum
47.19
Range
33.93
Interquartile Range
11.06
Skewness
-.203
.501
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113
Kurtosis
Mean
kadar vitamin d sesudah
intervensi
-.163
.972
60.6257
4.63580
95% Confidence Interval for
Lower Bound
50.9556
Mean
Upper Bound
70.2958
5% Trimmed Mean
59.6246
Median
59.9500
Variance
451.303
Std. Deviation
21.24390
Minimum
25.58
Maximum
114.46
Range
88.88
Interquartile Range
28.72
Skewness
.685
.501
Kurtosis
.574
.972
Rerata Kadar Vitamin D
Mean
kadar vitamin d sebelum
intervensi
N
Std. Deviation
Std. Error Mean
31.3524
21
9.14977
1.99664
60.6257
21
21.24390
4.63580
Pair 1
kadar vitamin d sesudah
intervensi
Uji Statistik T Berpasangan
Paired Differences
Mean
t
Std.
Std.
95% Confidence
Deviation
Error
Interval of the
Mean
Difference
Lower
df
Sig. (2tailed)
Upper
kadar vitamin d
sebelum
Pair 1
intervensi - kadar
-29.27333 22.09079
4.82061 -39.32894 -19.21773
-6.073
20
.000
vitamin d sesudah
intervensi
Universitas Sumatera Utara
114
4. KADAR VITAMIN D PADA KELOMPOK PLASEBO
Kadar Vitamin D Pada Kelompok Plasebo Descriptives
Statistic
Mean
29.8148
95% Confidence Interval for
Lower Bound
26.3820
Mean
Upper Bound
33.2475
5% Trimmed Mean
29.8950
Median
30.5200
Variance
kadar vitamin d sebelum
intervensi
Std. Deviation
7.54126
Minimum
15.68
Maximum
42.60
Range
26.92
Interquartile Range
12.28
Skewness
-.183
Mean
intervensi
-.889
.972
1.79675
Lower Bound
27.4330
Mean
Upper Bound
34.9289
5% Trimmed Mean
31.1696
Median
30.2700
Std. Deviation
67.794
8.23372
Minimum
16.52
Maximum
45.92
Range
29.40
Interquartile Range
11.46
Skewness
Kurtosis
.501
31.1810
95% Confidence Interval for
Variance
1.64564
56.871
Kurtosis
kadar vitamin d sesudah
Std. Error
.297
.501
-.561
.972
Universitas Sumatera Utara
115
Paired Samples Statistics
Mean
kadar vitamin d sebelum
intervensi
N
Std. Deviation
Std. Error Mean
29.8148
21
7.54126
1.64564
31.1810
21
8.23372
1.79675
Pair 1
kadar vitamin d sesudah
intervensi
Paired Samples Test
Paired Differences
Mean
t
Std.
Std.
95% Confidence
Deviation
Error
Interval of the
Mean
Difference
df
Sig. (2tailed)
Lower
Upper
-3.88571
1.15333
kadar vitamin d
sebelum
Pair 1
intervensi kadar vitamin d
-1.36619
5.53503
1.20784
-1.131
20
.271
sesudah
intervensi
Universitas Sumatera Utara
116
5. PERBANDINGAN KADAR VITAMIN D
Descriptive Statistics Sebelum Pemberian Vitamin D
N
Mean
Std.
Minimum
Maximum
Percentiles
Deviation
25th
50th
75th
(Median)
kadar vitamin
d sebelum
42
30.5836
8.31778
13.26
47.19
24.3675
31.9250
36.2100
42
1.50
.506
1
2
1.00
1.50
2.00
intervensi
no
responden
Uji Test Statistics
a,b
kadar vitamin d sebelum intervensi
Chi-Square
.320
df
1
Asymp. Sig.
.571
a. Kruskal Wallis Test
b. Grouping Variable: no responden
Descriptive Statistics Sesudah Pemberian Vitamin D
N
Mean
Std.
Minimum
Maximum
Deviation
Percentiles
25th
50th
75
th
(Median)
kadar vitamin d
sesudah
42
45.9033
21.80031
16.52
42
1.50
.506
1
114.46 29.1300
40.5850
60.6325
1.50
2.00
intervensi
no responden
2
1.00
Universitas Sumatera Utara
117
Test Statistics
a,b
kadar vitamin d sesudah intervensi
Chi-Square
22.726
Df
1
Asymp. Sig.
.000
a. Kruskal Wallis Test
6. PERBEDAAN ZONA
JUMLAH ZONA TERLIBAT SEBELUM INTERVENSI VIT D PADA KELOMPOK VITAMIN D
Frequency
Percent
Valid Percent
Cumulative
Percent
Dua Zona Terlibat
2
9.5
9.5
9.5
Tiga Zona Terlibat
6
28.6
28.6
38.1
Empat Zona Terlibat
8
38.1
38.1
76.2
Lima Zona Terlibat
2
9.5
9.5
85.7
Enam Zona Terlibat
3
14.3
14.3
100.0
21
100.0
100.0
Valid
Total
JUMLAH ZONA TERLIBAT SESUDAH INTERVENSI VIT D PADA KELOMPOK VITAMIN D
Frequency
Percent
Valid Percent
Cumulative
Percent
Valid
Satu Zona Terlibat
2
9.5
9.5
9.5
Dua Zona Terlibat
5
23.8
23.8
33.3
Tiga Zona Terlibat
7
33.3
33.3
66.7
Empat Zona Terlibat
5
23.8
23.8
90.5
Lima Zona Terlibat
1
4.8
4.8
95.2
Enam Zona Terlibat
1
4.8
4.8
100.0
21
100.0
100.0
Total
Universitas Sumatera Utara
118
PRE ZONA TERHADAP POLIMORFISME PADA KELOMPOK VITAMIN D
polimorfisme gen rvd
AA
0
1
1
2
Dua
Expected Count
.1
.8
1.1
2.0
Zona
% within jumlah zona terlibat
Terlibat
sebelum intervensi vit d
0.0%
50.0%
50.0%
100.0%
0.0%
12.5%
8.3%
9.5%
Count
0
1
5
6
Tiga
Expected Count
.3
2.3
3.4
6.0
Zona
% within jumlah zona terlibat
Terlibat
sebelum intervensi vit d
0.0%
16.7%
83.3%
100.0%
0.0%
12.5%
41.7%
28.6%
Count
0
4
4
8
Empat
Expected Count
.4
3.0
4.6
8.0
Zona
% within jumlah zona terlibat
Terlibat
sebelum intervensi vit d
0.0%
50.0%
50.0%
100.0%
0.0%
50.0%
33.3%
38.1%
Count
0
2
0
2
Lima
Expected Count
.1
.8
1.1
2.0
Zona
% within jumlah zona terlibat
Terlibat
sebelum intervensi vit d
0.0%
100.0%
0.0%
100.0%
0.0%
25.0%
0.0%
9.5%
Count
1
0
2
3
Enam
Expected Count
.1
1.1
1.7
3.0
Zona
% within jumlah zona terlibat
Terlibat
sebelum intervensi vit d
33.3%
0.0%
66.7%
100.0%
100.0%
0.0%
16.7%
14.3%
1
8
12
21
1.0
8.0
12.0
21.0
4.8%
38.1%
57.1%
100.0%
100.0%
100.0%
100.0%
100.0%
% within polimorfisme gen rvd
jumlah
terlibat
sebelum
intervensi
% within polimorfisme gen rvd
vit d
% within polimorfisme gen rvd
% within polimorfisme gen rvd
Count
Expected Count
Total
aa
Count
% within polimorfisme gen rvd
zona
Aa
Total
% within jumlah zona terlibat
sebelum intervensi vit d
% within polimorfisme gen rvd
Universitas Sumatera Utara
119
POST ZONA TERHADAP POLIMORFISME PADA KELOMPOK VITAMIN D
polimorfisme gen rvd
AA
Satu Zona
Terlibat
Dua Zona
Terlibat
jumlah
zona
Tiga Zona
Terlibat
terlibat
sesudah
intervensi
vit d
Empat Zona
Terlibat
Lima Zona
Terlibat
Enam Zona
Terlibat
Total
Count
Expected Count
% within jumlah zona terlibat
sesudah intervensi vit d
% within polimorfisme gen rvd
Count
Expected Count
% within jumlah zona terlibat
sesudah intervensi vit d
% within polimorfisme gen rvd
Count
Expected Count
% within jumlah zona terlibat
sesudah intervensi vit d
% within polimorfisme gen rvd
Count
Expected Count
% within jumlah zona terlibat
sesudah intervensi vit d
% within polimorfisme gen rvd
Count
Expected Count
% within jumlah zona terlibat
sesudah intervensi vit d
% within polimorfisme gen rvd
Count
Expected Count
% within jumlah zona terlibat
sesudah intervensi vit d
% within polimorfisme gen rvd
Count
Expected Count
% within jumlah zona terlibat
sesudah intervensi vit d
% within polimorfisme gen rvd
Aa
Total
aa
0
.1
1
.8
1
1.1
2
2.0
0.0%
50.0%
50.0%
100.0%
0.0%
0
.2
12.5%
1
1.9
8.3%
4
2.9
9.5%
5
5.0
0.0%
20.0%
80.0%
100.0%
0.0%
0
.3
12.5%
2
2.7
33.3%
5
4.0
23.8%
7
7.0
0.0%
28.6%
71.4%
100.0%
0.0%
1
.2
25.0%
4
1.9
41.7%
0
2.9
33.3%
5
5.0
20.0%
80.0%
0.0%
100.0%
100.0%
0
.0
50.0%
0
.4
0.0%
1
.6
23.8%
1
1.0
0.0%
0.0%
100.0%
100.0%
0.0%
0
.0
0.0%
0
.4
8.3%
1
.6
4.8%
1
1.0
0.0%
0.0%
100.0%
100.0%
0.0%
1
1.0
0.0%
8
8.0
8.3%
12
12.0
4.8%
21
21.0
4.8%
38.1%
57.1%
100.0%
100.0%
100.0%
100.0%
100.0%
Universitas Sumatera Utara
120
jumlah zona terlibat sebelum intervensi vit d * luas lesi pre thoraks
luas lesi pre thoraks
moderate
Count
Expected Count
Total
far advance
2
0
2
1.0
1.0
2.0
100.0%
0.0%
100.0%
18.2%
0.0%
9.5%
5
1
6
3.1
2.9
6.0
83.3%
16.7%
100.0%
45.5%
10.0%
28.6%
4
4
8
4.2
3.8
8.0
50.0%
50.0%
100.0%
36.4%
40.0%
38.1%
0
2
2
1.0
1.0
2.0
0.0%
100.0%
100.0%
0.0%
20.0%
9.5%
0
3
3
Dua Zona
Terlibat
% within jumlah zona terlibat
sebelum intervensi vit d
% within luas lesi pre thoraks
Count
Expected Count
Tiga Zona
Terlibat
% within jumlah zona terlibat
sebelum intervensi vit d
% within luas lesi pre thoraks
Count
jumlah zona
terlibat
Empat
Expected Count
sebelum
Zona
% within jumlah zona terlibat
intervensi vit d Terlibat
sebelum intervensi vit d
% within luas lesi pre thoraks
Count
Expected Count
Lima Zona
Terlibat
% within jumlah zona terlibat
sebelum intervensi vit d
% within luas lesi pre thoraks
Count
Expected Count
Enam Zona
% within jumlah zona terlibat
Terlibat
sebelum intervensi vit d
1.6
1.4
3.0
0.0%
100.0%
100.0%
% within luas lesi pre thoraks
0.0%
30.0%
14.3%
11
10
21
Count
Expected Count
Total
11.0
10.0
21.0
% within jumlah zona terlibat
sebelum intervensi vit d
52.4%
47.6%
100.0%
% within luas lesi pre thoraks
100.0%
100.0%
100.0%
Universitas Sumatera Utara
121
jumlah zona terlibat sesudah intervensi vit d * luasl lesi post thoraks
luasl lesi post thoraks
minimal
far advance
Count
2
0
0
2
Expected Count
.7
1.0
.4
2.0
100.0%
0.0%
0.0%
100.0%
28.6%
0.0%
0.0%
9.5%
3
1
1
5
1.7
2.4
1.0
5.0
60.0%
20.0%
20.0%
100.0%
42.9%
10.0%
25.0%
23.8%
2
5
0
7
2.3
3.3
1.3
7.0
28.6%
71.4%
0.0%
100.0%
28.6%
50.0%
0.0%
33.3%
0
4
1
5
1.7
2.4
1.0
5.0
0.0%
80.0%
20.0%
100.0%
0.0%
40.0%
25.0%
23.8%
Count
0
0
1
1
Expected Count
.3
.5
.2
1.0
0.0%
0.0%
100.0%
100.0%
0.0%
0.0%
25.0%
4.8%
0
0
1
1
.3
.5
.2
1.0
0.0%
0.0%
100.0%
100.0%
Satu Zona
% within jumlah zona terlibat
Terlibat
sesudah intervensi vit d
% within luasl lesi post
thoraks
Count
Expected Count
Dua Zona
% within jumlah zona terlibat
Terlibat
sesudah intervensi vit d
% within luasl lesi post
thoraks
Count
Expected Count
jumlah
Tiga Zona
% within jumlah zona terlibat
zona
Terlibat
sesudah intervensi vit d
terlibat
% within luasl lesi post
sesudah
thoraks
intervens
Count
i vit d
moderate
Total
Expected Count
Empat
Zona
Terlibat
% within jumlah zona terlibat
sesudah intervensi vit d
% within luasl lesi post
thoraks
Lima Zona
% within jumlah zona terlibat
Terlibat
sesudah intervensi vit d
% within luasl lesi post
thoraks
Count
Enam Zona Expected Count
Terlibat
% within jumlah zona terlibat
sesudah intervensi vit d
Universitas Sumatera Utara
122
% within luasl lesi post
thoraks
Count
Expected Count
% within jumlah zona terlibat
Total
sesudah intervensi vit d
% within luasl lesi post
thoraks
0.0%
0.0%
25.0%
4.8%
7
10
4
21
7.0
10.0
4.0
21.0
33.3%
47.6%
19.0%
100.0%
100.0%
100.0%
100.0%
100.0%
PADA KELOMPOK PLASEBO
jumlah zona terlibat sebelum intervensi vit d
Frequency
Percent
Valid Percent
Cumulative
Percent
Valid
Satu Zona Terlibat
1
4.8
4.8
4.8
Dua Zona Terlibat
5
23.8
23.8
28.6
Tiga Zona Terlibat
2
9.5
9.5
38.1
Empat Zona Terlibat
2
9.5
9.5
47.6
Lima Zona Terlibat
8
38.1
38.1
85.7
Enam Zona Terlibat
3
14.3
14.3
100.0
21
100.0
100.0
Total
jumlah zona terlibat sesudah intervensi vit d
Frequency
Percent
Valid Percent
Cumulative
Percent
Bersih
1
4.8
4.8
4.8
Satu Zona Terlibat
1
4.8
4.8
9.5
Dua Zona Terlibat
7
33.3
33.3
42.9
Tiga Zona Terlibat
2
9.5
9.5
52.4
Empat Zona Terlibat
2
9.5
9.5
61.9
Lima Zona Terlibat
6
28.6
28.6
90.5
Enam Zona Terlibat
2
9.5
9.5
100.0
21
100.0
100.0
Valid
Total
Universitas Sumatera Utara
123
KELOMPOK PLASEBO PADA POLIMORFISME
Crosstab SEBELUM PEMBERIAN PLASEBO
polimorfisme gen rvd
AA
Aa
Total
aa
Count
0
1
0
1
Expected Count
.1
.3
.5
1.0
0.0%
100.0%
0.0%
100.0%
0.0%
14.3%
0.0%
4.8%
Count
1
0
4
5
Expected Count
.7
1.7
2.6
5.0
20.0%
0.0%
80.0%
100.0%
33.3%
0.0%
36.4%
23.8%
Count
0
1
1
2
Expected Count
.3
.7
1.0
2.0
0.0%
50.0%
50.0%
100.0%
0.0%
14.3%
9.1%
9.5%
Count
2
0
0
2
Expected Count
.3
.7
1.0
2.0
100.0%
0.0%
0.0%
100.0%
66.7%
0.0%
0.0%
9.5%
0
4
4
8
1.1
2.7
4.2
8.0
0.0%
50.0%
50.0%
100.0%
0.0%
57.1%
36.4%
38.1%
Count
0
1
2
3
Expected Count
.4
1.0
1.6
3.0
0.0%
33.3%
66.7%
100.0%
0.0%
14.3%
18.2%
14.3%
3
7
11
21
Satu Zona
Terlibat
% within jumlah zona terlibat
sebelum intervensi vit d
% within polimorfisme gen rvd
Dua Zona
Terlibat
% within jumlah zona terlibat
sebelum intervensi vit d
% within polimorfisme gen rvd
Tiga Zona
Terlibat
% within jumlah zona terlibat
sebelum intervensi vit d
jumlah zona
% within polimorfisme gen rvd
terlibat sebelum
intervensi vit d
Empat Zona
Terlibat
% within jumlah zona terlibat
sebelum intervensi vit d
% within polimorfisme gen rvd
Count
Expected Count
Lima Zona
Terlibat
% within jumlah zona terlibat
sebelum intervensi vit d
% within polimorfisme gen rvd
Enam Zona
Terlibat
% within jumlah zona terlibat
sebelum intervensi vit d
% within polimorfisme gen rvd
Total
Count
Universitas Sumatera Utara
124
Expected Count
% within jumlah zona terlibat
sebelum intervensi vit d
% within polimorfisme gen rvd
3.0
7.0
11.0
21.0
14.3%
33.3%
52.4%
100.0%
100.0%
100.0%
100.0%
100.0%
Crosstab SESUDAH PEMBERIAN PLASEBO
polimorfisme gen rvd
AA
Aa
Total
aa
Count
0
0
1
1
Expected Count
.1
.3
.5
1.0
0.0%
0.0%
100.0%
100.0%
0.0%
0.0%
9.1%
4.8%
Count
0
1
0
1
Expected Count
.1
.3
.5
1.0
0.0%
100.0%
0.0%
100.0%
0.0%
14.3%
0.0%
4.8%
2
1
4
7
1.0
2.3
3.7
7.0
28.6%
14.3%
57.1%
100.0%
66.7%
14.3%
36.4%
33.3%
Count
0
1
1
2
Expected Count
.3
.7
1.0
2.0
0.0%
50.0%
50.0%
100.0%
0.0%
14.3%
9.1%
9.5%
% within jumlah zona
Bersih
terlibat sesudah intervensi
vit d
% within polimorfisme gen
rvd
Satu Zona
Terlibat
% within jumlah zona
terlibat sesudah intervensi
vit d
jumlah zona
% within polimorfisme gen
terlibat
rvd
sesudah
Count
intervensi vit d
Expected Count
Dua Zona
Terlibat
% within jumlah zona
terlibat sesudah intervensi
vit d
% within polimorfisme gen
rvd
Tiga Zona
Terlibat
% within jumlah zona
terlibat sesudah intervensi
vit d
% within polimorfisme gen
rvd
Universitas Sumatera Utara
125
Empat Zona
Terlibat
Count
1
1
0
2
Expected Count
.3
.7
1.0
2.0
50.0%
50.0%
0.0%
100.0%
33.3%
14.3%
0.0%
9.5%
Count
0
3
3
6
Expected Count
.9
2.0
3.1
6.0
0.0%
50.0%
50.0%
100.0%
0.0%
42.9%
27.3%
28.6%
Count
0
0
2
2
Expected Count
.3
.7
1.0
2.0
0.0%
0.0%
100.0%
100.0%
0.0%
0.0%
18.2%
9.5%
3
7
11
21
3.0
7.0
11.0
21.0
14.3%
33.3%
52.4%
100.0%
100.0%
100.0%
100.0%
100.0%
% within jumlah zona
terlibat sesudah intervensi
vit d
% within polimorfisme gen
rvd
Lima Zona
Terlibat
% within jumlah zona
terlibat sesudah intervensi
vit d
% within polimorfisme gen
rvd
Enam Zona
Terlibat
% within jumlah zona
terlibat sesudah intervensi
vit d
% within polimorfisme gen
rvd
Count
Expected Count
% within jumlah zona
Total
terlibat sesudah intervensi
vit d
% within polimorfisme gen
rvd
Universitas Sumatera Utara
126
JUMLAH ZONA BERDASARKAN LESI PRE PADA PLASEBO
jumlah zona terlibat sebelum intervensi vit d pada kelompok plasebo * luas lesi pre thoraks
Crosstabulation
luas lesi pre thoraks
minimal
Satu Zona
Terlibat
moderate
Total
far advance
Count
1
0
0
1
Expected Count
.0
.5
.5
1.0
100.0%
0.0%
0.0%
100.0%
100.0%
0.0%
0.0%
4.8%
Count
0
5
0
5
Expected Count
.2
2.4
2.4
5.0
0.0%
100.0%
0.0%
100.0%
0.0%
50.0%
0.0%
23.8%
Count
0
1
1
2
Expected Count
.1
1.0
1.0
2.0
0.0%
50.0%
50.0%
100.0%
0.0%
10.0%
10.0%
9.5%
Count
0
1
1
2
Expected Count
.1
1.0
1.0
2.0
0.0%
50.0%
50.0%
100.0%
0.0%
10.0%
10.0%
9.5%
% within jumlah zona
terlibat sebelum
intervensi vit d
% within luas lesi pre
thoraks
Dua Zona
Terlibat
% within jumlah zona
terlibat sebelum
intervensi vit d
% within luas lesi pre
thoraks
jumlah zona
terlibat sebelum
intervensi vit d
Tiga Zona
Terlibat
% within jumlah zona
terlibat sebelum
intervensi vit d
% within luas lesi pre
thoraks
Empat Zona
Terlibat
% within jumlah zona
terlibat sebelum
intervensi vit d
% within luas lesi pre
thoraks
Lima Zona
Count
0
3
5
8
Terlibat
Expected Count
.4
3.8
3.8
8.0
Universitas Sumatera Utara
127
% within jumlah zona
terlibat sebelum
0.0%
37.5%
62.5%
100.0%
0.0%
30.0%
50.0%
38.1%
Count
0
0
3
3
Expected Count
.1
1.4
1.4
3.0
0.0%
0.0%
100.0%
100.0%
0.0%
0.0%
30.0%
14.3%
1
10
10
21
1.0
10.0
10.0
21.0
4.8%
47.6%
47.6%
100.0%
100.0%
100.0%
100.0%
100.0%
intervensi vit d
% within luas lesi pre
thoraks
Enam Zona
Terlibat
% within jumlah zona
terlibat sebelum
intervensi vit d
% within luas lesi pre
thoraks
Count
Expected Count
% within jumlah zona
Total
terlibat sebelum
intervensi vit d
% within luas lesi pre
thoraks
Universitas Sumatera Utara
128
jumlah zona terlibat sesudah intervensi PLASEBO * luasl lesi post thoraks Crosstabulation
luasl lesi post thoraks
bersih
minimal
moderate
Total
far advance
Count
1
0
0
0
1
Expected Count
.0
.0
.7
.2
1.0
100.0%
0.0%
0.0%
0.0%
100.0%
100.0%
0.0%
0.0%
0.0%
4.8%
Count
0
1
0
0
1
Expected Count
.0
.0
.7
.2
1.0
0.0%
100.0%
0.0%
0.0%
100.0%
0.0%
100.0%
0.0%
0.0%
4.8%
% within jumlah zona
Bersih
terlibat sesudah
intervensi vit d
% within luasl lesi post
thoraks
Satu Zona
Terlibat
% within jumlah zona
terlibat sesudah
intervensi vit d
% within luasl lesi post
thoraks
jumlah zona
Count
0
0
7
0
7
terlibat
Expected Count
.3
.3
4.7
1.7
7.0
0.0%
0.0%
100.0%
0.0%
100.0%
0.0%
0.0%
50.0%
0.0%
33.3%
Count
0
0
2
0
2
Expected Count
.1
.1
1.3
.5
2.0
0.0%
0.0%
100.0%
0.0%
100.0%
0.0%
0.0%
14.3%
0.0%
9.5%
Count
0
0
2
0
2
Expected Count
.1
.1
1.3
.5
2.0
0.0%
0.0%
100.0%
0.0%
100.0%
sesudah
intervensi
vit d
Dua Zona
Terlibat
% within jumlah zona
terlibat sesudah
intervensi vit d
% within luasl lesi post
thoraks
Tiga Zona
Terlibat
% within jumlah zona
terlibat sesudah
intervensi vit d
% within luasl lesi post
thoraks
Empat Zona
Terlibat
% within jumlah zona
terlibat sesudah
intervensi vit d
Universitas Sumatera Utara
129
% within luasl lesi post
0.0%
0.0%
14.3%
0.0%
9.5%
Count
0
0
2
4
6
Expected Count
.3
.3
4.0
1.4
6.0
0.0%
0.0%
33.3%
66.7%
100.0%
0.0%
0.0%
14.3%
80.0%
28.6%
Count
0
0
1
1
2
Expected Count
.1
.1
1.3
.5
2.0
0.0%
0.0%
50.0%
50.0%
100.0%
0.0%
0.0%
7.1%
20.0%
9.5%
1
1
14
5
21
1.0
1.0
14.0
5.0
21.0
4.8%
4.8%
66.7%
23.8%
100.0%
100.0%
100.0%
100.0%
100.0%
100.0%
thoraks
Lima Zona
Terlibat
% within jumlah zona
terlibat sesudah
intervensi vit d
% within luasl lesi post
thoraks
Enam Zona
Terlibat
% within jumlah zona
terlibat sesudah
intervensi vit d
% within luasl lesi post
thoraks
Count
Expected Count
% within jumlah zona
Total
terlibat sesudah
intervensi vit d
% within luasl lesi post
thoraks
Universitas Sumatera Utara
130
UJI PERBEDAAN HASIL FOTO THORAKS PADA KELOMPOK VITAMIN D
Paired Samples Test
Paired Differences
Mean
t
Std.
Std. Error
95% Confidence
Deviation
Mean
Interval of the
df
Sig. (2tailed)
Difference
Lower
Upper
jumlah zona
terlibat sebelum
Pair 1
intervensi vit d
- jumlah zona
.857
.727
.159
.526
1.188
5.403
20
.000
terlibat sesudah
intervensi vit d
Paired Samples Statistics
Mean
jumlah zona terlibat sebelum
intervensi vit d
N
Std. Deviation
Std. Error Mean
3.90
21
1.179
.257
3.05
21
1.244
.271
Pair 1
jumlah zona terlibat sesudah
intervensi vit d
Uji Beda keterlibatan zona
JUMLAH ZONA TERLIBAT
SEBELUM INTERVENSI
VIT D PADA KELOMPOK
VITAMIN D
Paired Differences
Mean
t
Std.
Std.
95% Confidence Interval
Deviatio
Error
of the Difference
n
Mean
Lower
df
Sig. (2tailed)
Upper
jumlah zona
terlibat sebelum
Pair 1
intervensi vit d jumlah zona
.571
.926
.202
.150
.993
2.828
20
terlibat sesudah
intervensi vit d
Universitas Sumatera Utara
.010
131
7. PERBAIKAN FOTO TORAKS
Crosstab kelompok vit d sesudah
perbaikan
tidak ada
satu
dua
perbaikan
perbaikan
perbaikan
Count
0
2
0
2
Expected Count
.7
1.0
.4
2.0
0.0%
100.0%
0.0%
100.0%
% within perbaikan
0.0%
20.0%
0.0%
9.5%
% of Total
0.0%
9.5%
0.0%
9.5%
0
3
2
5
1.7
2.4
1.0
5.0
0.0%
60.0%
40.0%
100.0%
% within perbaikan
0.0%
30.0%
50.0%
23.8%
% of Total
0.0%
14.3%
9.5%
23.8%
3
3
1
7
2.3
3.3
1.3
7.0
42.9%
42.9%
14.3%
100.0%
% within perbaikan
42.9%
30.0%
25.0%
33.3%
% of Total
14.3%
14.3%
4.8%
33.3%
3
1
1
5
1.7
2.4
1.0
5.0
60.0%
20.0%
20.0%
100.0%
% within perbaikan
42.9%
10.0%
25.0%
23.8%
% of Total
14.3%
4.8%
4.8%
23.8%
Count
0
1
0
1
Expected Count
.3
.5
.2
1.0
0.0%
100.0%
0.0%
100.0%
% within perbaikan
0.0%
10.0%
0.0%
4.8%
% of Total
0.0%
4.8%
0.0%
4.8%
1
0
0
1
Satu Zona
% within jumlah zona terlibat
Terlibat
sesudah intervensi vit d
Count
Expected Count
Dua Zona
% within jumlah zona terlibat
Terlibat
sesudah intervensi vit d
Count
jumlah
zona
terlibat
Total
Expected Count
Tiga Zona
% within jumlah zona terlibat
Terlibat
sesudah intervensi vit d
sesudah
intervensi
vit d
Count
Expected Count
Empat Zona
% within jumlah zona terlibat
Terlibat
sesudah intervensi vit d
Lima Zona
% within jumlah zona terlibat
Terlibat
sesudah intervensi vit d
Enam Zona
Count
Universitas Sumatera Utara
132
Terlibat
Expected Count
% within jumlah zona terlibat
sesudah intervensi vit d
% within perbaikan
% of Total
Count
Expected Count
% within jumlah zona terlibat
Total
sesudah intervensi vit d
% within perbaikan
% of Total
.3
.5
.2
1.0
100.0%
0.0%
0.0%
100.0%
14.3%
0.0%
0.0%
4.8%
4.8%
0.0%
0.0%
4.8%
7
10
4
21
7.0
10.0
4.0
21.0
33.3%
47.6%
19.0%
100.0%
100.0%
100.0%
100.0%
100.0%
33.3%
47.6%
19.0%
100.0%
Crosstab pada kelompok plasebo sesudah
perbaikan
Total
tidak ada
satu
dua
tiga
perbaikan
perbaikan
perbaika
perbaikan
n
Bersih
jumlah zona
Count
0
0
0
1
1
Expected Count
.6
.1
.2
.0
1.0
0.0%
0.0%
0.0%
100.0%
100.0%
% within perbaikan
0.0%
0.0%
0.0%
100.0%
4.8%
% of Total
0.0%
0.0%
0.0%
4.8%
4.8%
Count
1
0
0
0
1
Expected Count
.6
.1
.2
.0
1.0
100.0%
0.0%
0.0%
0.0%
100.0%
% within jumlah zona terlibat
sesudah intervensi vit d
terlibat
Satu Zona
% within jumlah zona terlibat
sesudah
Terlibat
sesudah intervensi vit d
intervensi vit
% within perbaikan
7.7%
0.0%
0.0%
0.0%
4.8%
d
% of Total
4.8%
0.0%
0.0%
0.0%
4.8%
4
1
2
0
7
4.3
1.0
1.3
.3
7.0
57.1%
14.3%
28.6%
0.0%
100.0%
% within perbaikan
30.8%
33.3%
50.0%
0.0%
33.3%
% of Total
19.0%
4.8%
9.5%
0.0%
33.3%
0
0
2
0
2
Count
Expected Count
Dua Zona
% within jumlah zona terlibat
Terlibat
sesudah intervensi vit d
Tiga Zona
Count
Universitas Sumatera Utara
133
Terlibat
Expected Count
1.2
.3
.4
.1
2.0
0.0%
0.0%
100.0%
0.0%
100.0%
% within perbaikan
0.0%
0.0%
50.0%
0.0%
9.5%
% of Total
0.0%
0.0%
9.5%
0.0%
9.5%
1
1
0
0
2
1.2
.3
.4
.1
2.0
50.0%
50.0%
0.0%
0.0%
100.0%
% within perbaikan
7.7%
33.3%
0.0%
0.0%
9.5%
% of Total
4.8%
4.8%
0.0%
0.0%
9.5%
5
1
0
0
6
3.7
.9
1.1
.3
6.0
83.3%
16.7%
0.0%
0.0%
100.0%
% within perbaikan
38.5%
33.3%
0.0%
0.0%
28.6%
% of Total
23.8%
4.8%
0.0%
0.0%
28.6%
2
0
0
0
2
1.2
.3
.4
.1
2.0
100.0%
0.0%
0.0%
0.0%
100.0%
15.4%
0.0%
0.0%
0.0%
9.5%
9.5%
0.0%
0.0%
0.0%
9.5%
13
3
4
1
21
13.0
3.0
4.0
1.0
21.0
61.9%
14.3%
19.0%
4.8%
100.0%
100.0%
100.0%
100.0%
100.0%
100.0%
61.9%
14.3%
19.0%
4.8%
100.0%
% within jumlah zona terlibat
sesudah intervensi vit d
Count
Expected Count
Empat
Zona
Terlibat
% within jumlah zona terlibat
sesudah intervensi vit d
Count
Expected Count
Lima Zona
% within jumlah zona terlibat
Terlibat
sesudah intervensi vit d
Count
Expected Count
Enam Zona % within jumlah zona terlibat
Terlibat
sesudah intervensi vit d
% within perbaikan
% of Total
Count
Expected Count
Total
% within jumlah zona terlibat
sesudah intervensi vit d
% within perbaikan
% of Total
Universitas Sumatera Utara
134
8. PERBEDAAN JUMLH ZONA BERDASARKAN POLIMORFISME
JUMLAH ZONA TERLIBAT PRE PADA KELOMPOK VIT D
polimorfisme gen rvd
AA
Dua
Zona
Terlibat
0
1
1
2
Expected Count
.1
.8
1.1
2.0
0.0%
50.0%
50.0%
100.0%
0.0%
12.5%
8.3%
9.5%
0.0%
4.8%
4.8%
9.5%
Count
0
1
5
6
Expected Count
.3
2.3
3.4
6.0
0.0%
16.7%
83.3%
100.0%
0.0%
12.5%
41.7%
28.6%
0.0%
4.8%
23.8%
28.6%
Count
0
4
4
8
Expected Count
.4
3.0
4.6
8.0
0.0%
50.0%
50.0%
100.0%
0.0%
50.0%
33.3%
38.1%
0.0%
19.0%
19.0%
38.1%
Count
0
2
0
2
Expected Count
.1
.8
1.1
2.0
0.0%
100.0%
0.0%
100.0%
0.0%
25.0%
0.0%
9.5%
0.0%
9.5%
0.0%
9.5%
% within jumlah zona
terlibat sebelum intervensi
vit d
rvd
% of Total
Zona
Terlibat
% within jumlah zona
terlibat sebelum intervensi
vit d
% within polimorfisme gen
rvd
jumlah zona
aa
Count
% within polimorfisme gen
Tiga
Aa
Total
% of Total
terlibat sebelum
intervensi vit d
Empat
Zona
Terlibat
% within jumlah zona
terlibat sebelum intervensi
vit d
% within polimorfisme gen
rvd
% of Total
Lima
Zona
Terlibat
% within jumlah zona
terlibat sebelum intervensi
vit d
% within polimorfisme gen
rvd
% of Total
Universitas Sumatera Utara
135
Enam
Zona
Terlibat
Count
1
0
2
3
Expected Count
.1
1.1
1.7
3.0
33.3%
0.0%
66.7%
100.0%
100.0%
0.0%
16.7%
14.3%
4.8%
0.0%
9.5%
14.3%
1
8
12
21
1.0
8.0
12.0
21.0
4.8%
38.1%
57.1%
100.0%
100.0%
100.0%
100.0%
100.0%
4.8%
38.1%
57.1%
100.0%
% within jumlah zona
terlibat sebelum intervensi
vit d
% within polimorfisme gen
rvd
% of Total
Count
Expected Count
% within jumlah zona
terlibat sebelum intervensi
Total
vit d
% within polimorfisme gen
rvd
% of Total
JUMLAH ZONA TERLIBAT PRE PADA KELOMPOK VIT D
polimorfisme gen rvd
AA
aa
Count
0
1
1
2
Expected Count
.1
.8
1.1
2.0
0.0%
50.0%
50.0%
100.0%
% within polimorfisme gen rvd
0.0%
12.5%
8.3%
9.5%
% of Total
0.0%
4.8%
4.8%
9.5%
Count
0
1
5
6
Expected Count
.3
2.3
3.4
6.0
0.0%
16.7%
83.3%
100.0%
% within polimorfisme gen rvd
0.0%
12.5%
41.7%
28.6%
% of Total
0.0%
4.8%
23.8%
28.6%
Count
0
4
4
8
Empat Zona
Expected Count
.4
3.0
4.6
8.0
Terlibat
% within jumlah zona terlibat
0.0%
50.0%
50.0%
100.0%
Dua Zona
% within jumlah zona terlibat
Terlibat
sebelum intervensi vit d
jumlah zona
terlibat sebelum
intervensi vit d
Aa
Total
Tiga Zona
% within jumlah zona terlibat
Terlibat
sebelum intervensi vit d
sebelum intervensi vit d
Universitas Sumatera Utara
136
% within polimorfisme gen rvd
0.0%
50.0%
33.3%
38.1%
% of Total
0.0%
19.0%
19.0%
38.1%
Count
0
2
0
2
Expected Count
.1
.8
1.1
2.0
0.0%
100.0%
0.0%
100.0%
% within polimorfisme gen rvd
0.0%
25.0%
0.0%
9.5%
% of Total
0.0%
9.5%
0.0%
9.5%
Count
1
0
2
3
Expected Count
.1
1.1
1.7
3.0
33.3%
0.0%
66.7%
100.0%
100.0%
0.0%
16.7%
14.3%
4.8%
0.0%
9.5%
14.3%
1
8
12
21
1.0
8.0
12.0
21.0
4.8%
38.1%
57.1%
100.0%
100.0%
100.0%
100.0%
100.0%
4.8%
38.1%
57.1%
100.0%
Lima Zona
% within jumlah zona terlibat
Terlibat
sebelum intervensi vit d
Enam Zona
% within jumlah zona terlibat
Terlibat
sebelum intervensi vit d
% within polimorfisme gen rvd
% of Total
Count
Expected Count
% within jumlah zona terlibat
Total
sebelum intervensi vit d
% within polimorfisme gen rvd
% of Total
PADA KELOMPOK PLASEBO
SEBELUM PADA KELOMPOK PLASEBO
polimorfisme gen rvd
AA
Aa
Total
aa
Count
0
1
0
1
Expected Count
.1
.3
.5
1.0
0.0%
100.0%
0.0%
100.0%
0.0%
14.3%
0.0%
4.8%
0.0%
4.8%
0.0%
4.8%
% within jumlah zona
jumlah zona
Satu Zona
terlibat sebelum
terlibat
Terlibat
intervensi vit d
sebelum
% within polimorfisme
intervensi vit d
gen rvd
% of Total
Dua Zona
Count
1
0
4
5
Terlibat
Expected Count
.7
1.7
2.6
5.0
Universitas Sumatera Utara
137
% within jumlah zona
terlibat sebelum
20.0%
0.0%
80.0%
100.0%
33.3%
0.0%
36.4%
23.8%
4.8%
0.0%
19.0%
23.8%
Count
0
1
1
2
Expected Count
.3
.7
1.0
2.0
0.0%
50.0%
50.0%
100.0%
0.0%
14.3%
9.1%
9.5%
0.0%
4.8%
4.8%
9.5%
Count
2
0
0
2
Expected Count
.3
.7
1.0
2.0
100.0%
0.0%
0.0%
100.0%
66.7%
0.0%
0.0%
9.5%
9.5%
0.0%
0.0%
9.5%
0
4
4
8
1.1
2.7
4.2
8.0
0.0%
50.0%
50.0%
100.0%
0.0%
57.1%
36.4%
38.1%
0.0%
19.0%
19.0%
38.1%
Count
0
1
2
3
Expected Count
.4
1.0
1.6
3.0
0.0%
33.3%
66.7%
100.0%
0.0%
14.3%
18.2%
14.3%
intervensi vit d
% within polimorfisme
gen rvd
% of Total
% within jumlah zona
Tiga Zona
terlibat sebelum
Terlibat
intervensi vit d
% within polimorfisme
gen rvd
% of Total
% within jumlah zona
Empat Zona
terlibat sebelum
Terlibat
intervensi vit d
% within polimorfisme
gen rvd
% of Total
Count
Expected Count
% within jumlah zona
Lima Zona
terlibat sebelum
Terlibat
intervensi vit d
% within polimorfisme
gen rvd
% of Total
Enam Zona
Terlibat
% within jumlah zona
terlibat sebelum
intervensi vit d
% within polimorfisme
gen rvd
Universitas Sumatera Utara
138
% of Total
0.0%
4.8%
9.5%
14.3%
3
7
11
21
3.0
7.0
11.0
21.0
14.3%
33.3%
52.4%
100.0%
100.0%
100.0%
100.0%
100.0%
14.3%
33.3%
52.4%
100.0%
Count
Expected Count
% within jumlah zona
terlibat sebelum
Total
intervensi vit d
% within polimorfisme
gen rvd
% of Total
SEBELUM PADA KELOMPOK PLASEBO
polimorfisme gen rvd
AA
Aa
Total
aa
Count
0
0
2
2
Expected Count
.3
.7
1.0
2.0
0.0%
0.0%
100.0%
100.0%
0.0%
0.0%
18.2%
9.5%
0.0%
0.0%
9.5%
9.5%
Count
0
1
0
1
Expected Count
.1
.3
.5
1.0
0.0%
100.0%
0.0%
100.0%
0.0%
14.3%
0.0%
4.8%
0.0%
4.8%
0.0%
4.8%
Count
2
1
3
6
Expected Count
.9
2.0
3.1
6.0
33.3%
16.7%
50.0%
100.0%
66.7%
14.3%
27.3%
28.6%
9.5%
4.8%
14.3%
28.6%
% within jumlah zona
Bersih
terlibat sesudah intervensi
vit d
% within polimorfisme gen
rvd
% of Total
jumlah zona
terlibat sesudah
intervensi vit d
% within jumlah zona
Satu Zona
terlibat sesudah intervensi
Terlibat
vit d
% within polimorfisme gen
rvd
% of Total
% within jumlah zona
Dua Zona
terlibat sesudah intervensi
Terlibat
vit d
% within polimorfisme gen
rvd
% of Total
Universitas Sumatera Utara
139
Count
0
1
1
2
Expected Count
.3
.7
1.0
2.0
0.0%
50.0%
50.0%
100.0%
0.0%
14.3%
9.1%
9.5%
0.0%
4.8%
4.8%
9.5%
Count
1
1
0
2
Expected Count
.3
.7
1.0
2.0
50.0%
50.0%
0.0%
100.0%
33.3%
14.3%
0.0%
9.5%
4.8%
4.8%
0.0%
9.5%
Count
0
3
3
6
Expected Count
.9
2.0
3.1
6.0
0.0%
50.0%
50.0%
100.0%
0.0%
42.9%
27.3%
28.6%
0.0%
14.3%
14.3%
28.6%
Count
0
0
2
2
Expected Count
.3
.7
1.0
2.0
0.0%
0.0%
100.0%
100.0%
0.0%
0.0%
18.2%
9.5%
0.0%
0.0%
9.5%
9.5%
3
7
11
21
3.0
7.0
11.0
21.0
14.3%
33.3%
52.4%
100.0%
% within jumlah zona
Tiga Zona
terlibat sesudah intervensi
Terlibat
vit d
% within polimorfisme gen
rvd
% of Total
% within jumlah zona
Empat Zona
terlibat sesudah intervensi
Terlibat
vit d
% within polimorfisme gen
rvd
% of Total
% within jumlah zona
Lima Zona
terlibat sesudah intervensi
Terlibat
vit d
% within polimorfisme gen
rvd
% of Total
% within jumlah zona
Enam Zona
terlibat sesudah intervensi
Terlibat
vit d
% within polimorfisme gen
rvd
% of Total
Count
Expected Count
Total
% within jumlah zona
terlibat sesudah intervensi
vit d
Universitas Sumatera Utara
140
% within polimorfisme gen
rvd
% of Total
100.0%
100.0%
100.0%
100.0%
14.3%
33.3%
52.4%
100.0%
9. PERBAIKAN TERHADAP POLIMORFISME
polimorfisme gen rvd * luas lesi pre thoraks Crosstabulation
luas lesi pre thoraks
moderate
Count
% within polimorfisme gen
rvd
Total
far advance
0
1
1
0.0%
100.0%
100.0%
0.0%
10.0%
4.8%
0.0%
4.8%
4.8%
5
3
8
62.5%
37.5%
100.0%
45.5%
30.0%
38.1%
23.8%
14.3%
38.1%
6
6
12
50.0%
50.0%
100.0%
54.5%
60.0%
57.1%
28.6%
28.6%
57.1%
11
10
21
52.4%
47.6%
100.0%
100.0%
100.0%
100.0%
52.4%
47.6%
100.0%
AA
% within luas lesi pre
thoraks
% of Total
Count
% within polimorfisme gen
rvd
polimorfisme gen rvd
Aa
% within luas lesi pre
thoraks
% of Total
Count
% within polimorfisme gen
rvd
aa
% within luas lesi pre
thoraks
% of Total
Count
% within polimorfisme gen
rvd
Total
% within luas lesi pre
thoraks
% of Total
polimorfisme gen rvd * luasl lesi post thoraks Crosstabulation
Universitas Sumatera Utara
141
luasl lesi post thoraks
minimal
Count
% within polimorfisme gen
rvd
moderate
Total
far advance
0
1
0
1
0.0%
100.0%
0.0%
100.0%
0.0%
10.0%
0.0%
4.8%
0.0%
4.8%
0.0%
4.8%
2
5
1
8
25.0%
62.5%
12.5%
100.0%
28.6%
50.0%
25.0%
38.1%
9.5%
23.8%
4.8%
38.1%
5
4
3
12
41.7%
33.3%
25.0%
100.0%
71.4%
40.0%
75.0%
57.1%
23.8%
19.0%
14.3%
57.1%
7
10
4
21
33.3%
47.6%
19.0%
100.0%
100.0%
100.0%
100.0%
100.0%
33.3%
47.6%
19.0%
100.0%
AA
% within luasl lesi post
thoraks
% of Total
Count
% within polimorfisme gen
rvd
polimorfisme gen rvd
Aa
% within luasl lesi post
thoraks
% of Total
Count
% within polimorfisme gen
rvd
aa
% within luasl lesi post
thoraks
% of Total
Count
% within polimorfisme gen
rvd
Total
% within luasl lesi post
thoraks
% of Total
polimorfisme gen rvd * luas lesi pre thoraks Crosstabulation
luas lesi pre thoraks
minimal
Count
AA
far advance
0
2
1
3
0.0%
66.7%
33.3%
100.0%
% within luas lesi pre thoraks
0.0%
20.0%
10.0%
14.3%
% of Total
0.0%
9.5%
4.8%
14.3%
% within polimorfisme gen
polimorfisme gen rvd
moderate
Total
rvd
Universitas Sumatera Utara
142
Count
1
3
3
7
14.3%
42.9%
42.9%
100.0%
100.0%
30.0%
30.0%
33.3%
4.8%
14.3%
14.3%
33.3%
0
5
6
11
0.0%
45.5%
54.5%
100.0%
% within luas lesi pre thoraks
0.0%
50.0%
60.0%
52.4%
% of Total
0.0%
23.8%
28.6%
52.4%
1
10
10
21
4.8%
47.6%
47.6%
100.0%
100.0%
100.0%
100.0%
100.0%
4.8%
47.6%
47.6%
100.0%
% within polimorfisme gen
Aa
rvd
% within luas lesi pre thoraks
% of Total
Count
% within polimorfisme gen
aa
rvd
Count
% within polimorfisme gen
rvd
Total
% within luas lesi pre thoraks
% of Total
polimorfisme gen rvd * luasl lesi post thoraks Crosstabulation
luasl lesi post thoraks
bersih
Count
% within polimorfisme gen rvd
AA
% within luasl lesi post
thoraks
% of Total
Count
% within polimorfisme gen rvd
polimorfisme
gen rvd
Aa
% within luasl lesi post
thoraks
% of Total
Count
% within polimorfisme gen rvd
aa
% within luasl lesi post
thoraks
% of Total
Total
Count
minimal
moderate
Total
far advance
0
0
3
0
3
0.0%
0.0%
100.0%
0.0%
100.0%
0.0%
0.0%
21.4%
0.0%
14.3%
0.0%
0.0%
14.3%
0.0%
14.3%
0
1
4
2
7
0.0%
14.3%
57.1%
28.6%
100.0%
0.0%
100.0%
28.6%
40.0%
33.3%
0.0%
4.8%
19.0%
9.5%
33.3%
1
0
7
3
11
9.1%
0.0%
63.6%
27.3%
100.0%
100.0%
0.0%
50.0%
60.0%
52.4%
4.8%
0.0%
33.3%
14.3%
52.4%
1
1
14
5
21
Universitas Sumatera Utara
143
% within polimorfisme gen rvd
% within luasl lesi post
thoraks
% of Total
4.8%
4.8%
66.7%
23.8%
100.0%
100.0%
100.0%
100.0%
100.0%
100.0%
4.8%
4.8%
66.7%
23.8%
100.0%
10. HUBUNGAN FOTO THORAKS DENGAN POLIMORFISME
perbaikan pada kelompok yang diberikan vitamin D * Polimorfis Crosstabulation
Polimorfis
AA+Aa
perbaikan pada kedua
tidak ada perbaikan foto
Count
thorax
Expected Count
kelompok
Total
aa
3
4
7
3.0
4.0
7.0
6
8
14
6.0
8.0
14.0
9
12
21
9.0
12.0
21.0
Count
ada perbaikan foto thorax
Expected Count
Count
Total
Expected Count
Chi-Square Tests
Value
Pearson Chi-Square
Continuity Correction
df
Likelihood Ratio
Exact Sig. (2-
Exact Sig. (1-
sided)
sided)
sided)
a
1
1.000
.000
1
1.000
.000
1
1.000
.000
b
Asymp. Sig. (2-
Fisher's Exact Test
Linear-by-Linear Association
N of Valid Cases
1.000
.000
1
.681
1.000
21
a. 2 cells (50.0%) have expected count less than 5. The minimum expected count is 3.00.
b. Computed only for a 2x2 table
Universitas Sumatera Utara
144
perbaikan pada kedua kelompok * Polimorfis Crosstabulation
Polimorfis
AA+Aa
perbaikan pada kedua
tidak ada perbaikan foto
Count
thorax
Expected Count
kelompok
Total
aa
5
8
13
6.2
6.8
13.0
5
3
8
Expected Count
3.8
4.2
8.0
Count
10
11
21
10.0
11.0
21.0
Count
ada perbaikan foto thorax
Total
Expected Count
Chi-Square Tests
Value
Pearson Chi-Square
Continuity Correction
df
Likelihood Ratio
Exact Sig. (2-
Exact Sig. (1-
sided)
sided)
sided)
a
1
.284
.386
1
.534
1.156
1
.282
1.147
b
Asymp. Sig. (2-
Fisher's Exact Test
Linear-by-Linear Association
N of Valid Cases
.387
1.093
1
.268
.296
21
a. 2 cells (50.0%) have expected count less than 5. The minimum expected count is 3.81.
b. Computed only for a 2x2 table
Universitas Sumatera Utara
145
Universitas Sumatera Utara
146
Universitas Sumatera Utara
LAMPIRAN
Universitas Sumatera Utara
107
LAMPIRAN DOKUMEN PENELITIAN
Gmbr 1. Isolasi DNA
Gambar 4. KIT Vitamin D
Gambar 2. RFLP
Gambar 5. KIT Vitamin D
Universitas Sumatera Utara
108
Gambar 7. Penomoran sampel
Gambar 6. Persiapan RFLP
Gambar 8: Kit Vitamin D
Gambar 9 Buffer
Universitas Sumatera Utara
109
Gambar10. Meemberikan vitamin D ke sampel
Gambar 11. Sampel Minum Vitamin D
Gambar: PCR
Gambar : Hasil RFLP Polimorfisme
Gambar: RFLP Polimorfisme Apa1
Universitas Sumatera Utara
110
LAMPIRAN : PENGOLAHAN DATA BERDASARKAN SPSS
1. KARAKTERISTIK RESPONDEN
Umur Responden Kelompok Vitamin D
Frequency
Percent
Valid Percent
Valid
1
2
11
9
52.4
42.9
52.4
42.9
3
Total
1
21
4.8
100.0
4.8
100.0
Cumulative
Percent
52.4
95.2
100.0
Statistics
Umur Responden Kelompok Vitamin D
N
Valid
Missing
21
0
34.00
31.00
12.128
Mean
Median
Std. Deviation
Umur Responden Kelompok Plasebo
Frequency
Percent
Valid Percent
18-34
35-52
Valid
53-69
4
9
8
19.0
42.9
38.1
19.0
42.9
38.1
Total
21
100.0
100.0
Statistics
Umur Responden Kelompok Plasebo
Valid
N
Missing
Mean
Median
Std. Deviation
Cumulative
Percent
19.0
61.9
100.0
21
0
46.19
49.00
14.500
Universitas Sumatera Utara
111
Jenis kelamin responden Kelompok Vitamin D
Frequency
Percent
Valid Percent
laki-laki
Valid perempuan
Total
13
8
21
61.9
38.1
100.0
Cumulative
Percent
61.9
61.9
38.1
100.0
100.0
Jenis Kelamin Responden Kelompok Plasebo
Frequency
Percent
Valid Percent
Cumulative
Percent
laki-laki
Valid
perempuan
Total
13
61.9
61.9
61.9
8
38.1
38.1
100.0
21
100.0
100.0
Pekerjaan Responden Kelompok Vitamin D
Frequency
mahasiswa
bekerja
Valid tidak
bekerja
Total
Percent
Valid Percent
3
13
14.3
61.9
14.3
61.9
Cumulative
Percent
14.3
76.2
5
23.8
23.8
100.0
21
100.0
100.0
Pekerjaan Responden Kelompok Plasebo
Frequency
Percent
Valid Percent
Cumulative
Percent
mahasiswa
bekerja
1
4.8
4.8
4.8
13
61.9
61.9
66.7
7
33.3
33.3
100.0
21
100.0
100.0
Valid
tidak bekerja
Total
Universitas Sumatera Utara
112
2. STATUS VITAMIN D
Kadar Vitamin D Sebelum intervensi Pada Kelompok Vitamin D
Frequency
Percent
Valid Percent
Cumulative
Percent
Defisiensi
3
14.3
14.3
14.3
insufisiensi
6
28.6
28.6
42.9
Valid
optimal
12
57.1
57.1
100.0
Total
21
100.0
100.0
Kadar Vitamin D Sebelum Intervensi Kelompok Plasebo
Frequency
Percent
Valid Percent
Cumulative
Percent
Defisiensi
2
9.5
9.5
9.5
insufisiensi
8
38.1
38.1
47.6
Valid
optimal
11
52.4
52.4
100.0
Total
21
100.0
100.0
3. KADAR VITAMIN D PADA KELOMPOK YANG DIBERIKAN VITAMIN D
Descriptives Kadar Vitamin D
Statistic
Mean
31.3524
95% Confidence Interval for
Lower Bound
27.1875
Mean
Upper Bound
35.5173
5% Trimmed Mean
31.4721
Median
32.6700
kadar vitamin d sebelum
Variance
intervensi
Std. Deviation
Std. Error
1.99664
83.718
9.14977
Minimum
13.26
Maximum
47.19
Range
33.93
Interquartile Range
11.06
Skewness
-.203
.501
Universitas Sumatera Utara
113
Kurtosis
Mean
kadar vitamin d sesudah
intervensi
-.163
.972
60.6257
4.63580
95% Confidence Interval for
Lower Bound
50.9556
Mean
Upper Bound
70.2958
5% Trimmed Mean
59.6246
Median
59.9500
Variance
451.303
Std. Deviation
21.24390
Minimum
25.58
Maximum
114.46
Range
88.88
Interquartile Range
28.72
Skewness
.685
.501
Kurtosis
.574
.972
Rerata Kadar Vitamin D
Mean
kadar vitamin d sebelum
intervensi
N
Std. Deviation
Std. Error Mean
31.3524
21
9.14977
1.99664
60.6257
21
21.24390
4.63580
Pair 1
kadar vitamin d sesudah
intervensi
Uji Statistik T Berpasangan
Paired Differences
Mean
t
Std.
Std.
95% Confidence
Deviation
Error
Interval of the
Mean
Difference
Lower
df
Sig. (2tailed)
Upper
kadar vitamin d
sebelum
Pair 1
intervensi - kadar
-29.27333 22.09079
4.82061 -39.32894 -19.21773
-6.073
20
.000
vitamin d sesudah
intervensi
Universitas Sumatera Utara
114
4. KADAR VITAMIN D PADA KELOMPOK PLASEBO
Kadar Vitamin D Pada Kelompok Plasebo Descriptives
Statistic
Mean
29.8148
95% Confidence Interval for
Lower Bound
26.3820
Mean
Upper Bound
33.2475
5% Trimmed Mean
29.8950
Median
30.5200
Variance
kadar vitamin d sebelum
intervensi
Std. Deviation
7.54126
Minimum
15.68
Maximum
42.60
Range
26.92
Interquartile Range
12.28
Skewness
-.183
Mean
intervensi
-.889
.972
1.79675
Lower Bound
27.4330
Mean
Upper Bound
34.9289
5% Trimmed Mean
31.1696
Median
30.2700
Std. Deviation
67.794
8.23372
Minimum
16.52
Maximum
45.92
Range
29.40
Interquartile Range
11.46
Skewness
Kurtosis
.501
31.1810
95% Confidence Interval for
Variance
1.64564
56.871
Kurtosis
kadar vitamin d sesudah
Std. Error
.297
.501
-.561
.972
Universitas Sumatera Utara
115
Paired Samples Statistics
Mean
kadar vitamin d sebelum
intervensi
N
Std. Deviation
Std. Error Mean
29.8148
21
7.54126
1.64564
31.1810
21
8.23372
1.79675
Pair 1
kadar vitamin d sesudah
intervensi
Paired Samples Test
Paired Differences
Mean
t
Std.
Std.
95% Confidence
Deviation
Error
Interval of the
Mean
Difference
df
Sig. (2tailed)
Lower
Upper
-3.88571
1.15333
kadar vitamin d
sebelum
Pair 1
intervensi kadar vitamin d
-1.36619
5.53503
1.20784
-1.131
20
.271
sesudah
intervensi
Universitas Sumatera Utara
116
5. PERBANDINGAN KADAR VITAMIN D
Descriptive Statistics Sebelum Pemberian Vitamin D
N
Mean
Std.
Minimum
Maximum
Percentiles
Deviation
25th
50th
75th
(Median)
kadar vitamin
d sebelum
42
30.5836
8.31778
13.26
47.19
24.3675
31.9250
36.2100
42
1.50
.506
1
2
1.00
1.50
2.00
intervensi
no
responden
Uji Test Statistics
a,b
kadar vitamin d sebelum intervensi
Chi-Square
.320
df
1
Asymp. Sig.
.571
a. Kruskal Wallis Test
b. Grouping Variable: no responden
Descriptive Statistics Sesudah Pemberian Vitamin D
N
Mean
Std.
Minimum
Maximum
Deviation
Percentiles
25th
50th
75
th
(Median)
kadar vitamin d
sesudah
42
45.9033
21.80031
16.52
42
1.50
.506
1
114.46 29.1300
40.5850
60.6325
1.50
2.00
intervensi
no responden
2
1.00
Universitas Sumatera Utara
117
Test Statistics
a,b
kadar vitamin d sesudah intervensi
Chi-Square
22.726
Df
1
Asymp. Sig.
.000
a. Kruskal Wallis Test
6. PERBEDAAN ZONA
JUMLAH ZONA TERLIBAT SEBELUM INTERVENSI VIT D PADA KELOMPOK VITAMIN D
Frequency
Percent
Valid Percent
Cumulative
Percent
Dua Zona Terlibat
2
9.5
9.5
9.5
Tiga Zona Terlibat
6
28.6
28.6
38.1
Empat Zona Terlibat
8
38.1
38.1
76.2
Lima Zona Terlibat
2
9.5
9.5
85.7
Enam Zona Terlibat
3
14.3
14.3
100.0
21
100.0
100.0
Valid
Total
JUMLAH ZONA TERLIBAT SESUDAH INTERVENSI VIT D PADA KELOMPOK VITAMIN D
Frequency
Percent
Valid Percent
Cumulative
Percent
Valid
Satu Zona Terlibat
2
9.5
9.5
9.5
Dua Zona Terlibat
5
23.8
23.8
33.3
Tiga Zona Terlibat
7
33.3
33.3
66.7
Empat Zona Terlibat
5
23.8
23.8
90.5
Lima Zona Terlibat
1
4.8
4.8
95.2
Enam Zona Terlibat
1
4.8
4.8
100.0
21
100.0
100.0
Total
Universitas Sumatera Utara
118
PRE ZONA TERHADAP POLIMORFISME PADA KELOMPOK VITAMIN D
polimorfisme gen rvd
AA
0
1
1
2
Dua
Expected Count
.1
.8
1.1
2.0
Zona
% within jumlah zona terlibat
Terlibat
sebelum intervensi vit d
0.0%
50.0%
50.0%
100.0%
0.0%
12.5%
8.3%
9.5%
Count
0
1
5
6
Tiga
Expected Count
.3
2.3
3.4
6.0
Zona
% within jumlah zona terlibat
Terlibat
sebelum intervensi vit d
0.0%
16.7%
83.3%
100.0%
0.0%
12.5%
41.7%
28.6%
Count
0
4
4
8
Empat
Expected Count
.4
3.0
4.6
8.0
Zona
% within jumlah zona terlibat
Terlibat
sebelum intervensi vit d
0.0%
50.0%
50.0%
100.0%
0.0%
50.0%
33.3%
38.1%
Count
0
2
0
2
Lima
Expected Count
.1
.8
1.1
2.0
Zona
% within jumlah zona terlibat
Terlibat
sebelum intervensi vit d
0.0%
100.0%
0.0%
100.0%
0.0%
25.0%
0.0%
9.5%
Count
1
0
2
3
Enam
Expected Count
.1
1.1
1.7
3.0
Zona
% within jumlah zona terlibat
Terlibat
sebelum intervensi vit d
33.3%
0.0%
66.7%
100.0%
100.0%
0.0%
16.7%
14.3%
1
8
12
21
1.0
8.0
12.0
21.0
4.8%
38.1%
57.1%
100.0%
100.0%
100.0%
100.0%
100.0%
% within polimorfisme gen rvd
jumlah
terlibat
sebelum
intervensi
% within polimorfisme gen rvd
vit d
% within polimorfisme gen rvd
% within polimorfisme gen rvd
Count
Expected Count
Total
aa
Count
% within polimorfisme gen rvd
zona
Aa
Total
% within jumlah zona terlibat
sebelum intervensi vit d
% within polimorfisme gen rvd
Universitas Sumatera Utara
119
POST ZONA TERHADAP POLIMORFISME PADA KELOMPOK VITAMIN D
polimorfisme gen rvd
AA
Satu Zona
Terlibat
Dua Zona
Terlibat
jumlah
zona
Tiga Zona
Terlibat
terlibat
sesudah
intervensi
vit d
Empat Zona
Terlibat
Lima Zona
Terlibat
Enam Zona
Terlibat
Total
Count
Expected Count
% within jumlah zona terlibat
sesudah intervensi vit d
% within polimorfisme gen rvd
Count
Expected Count
% within jumlah zona terlibat
sesudah intervensi vit d
% within polimorfisme gen rvd
Count
Expected Count
% within jumlah zona terlibat
sesudah intervensi vit d
% within polimorfisme gen rvd
Count
Expected Count
% within jumlah zona terlibat
sesudah intervensi vit d
% within polimorfisme gen rvd
Count
Expected Count
% within jumlah zona terlibat
sesudah intervensi vit d
% within polimorfisme gen rvd
Count
Expected Count
% within jumlah zona terlibat
sesudah intervensi vit d
% within polimorfisme gen rvd
Count
Expected Count
% within jumlah zona terlibat
sesudah intervensi vit d
% within polimorfisme gen rvd
Aa
Total
aa
0
.1
1
.8
1
1.1
2
2.0
0.0%
50.0%
50.0%
100.0%
0.0%
0
.2
12.5%
1
1.9
8.3%
4
2.9
9.5%
5
5.0
0.0%
20.0%
80.0%
100.0%
0.0%
0
.3
12.5%
2
2.7
33.3%
5
4.0
23.8%
7
7.0
0.0%
28.6%
71.4%
100.0%
0.0%
1
.2
25.0%
4
1.9
41.7%
0
2.9
33.3%
5
5.0
20.0%
80.0%
0.0%
100.0%
100.0%
0
.0
50.0%
0
.4
0.0%
1
.6
23.8%
1
1.0
0.0%
0.0%
100.0%
100.0%
0.0%
0
.0
0.0%
0
.4
8.3%
1
.6
4.8%
1
1.0
0.0%
0.0%
100.0%
100.0%
0.0%
1
1.0
0.0%
8
8.0
8.3%
12
12.0
4.8%
21
21.0
4.8%
38.1%
57.1%
100.0%
100.0%
100.0%
100.0%
100.0%
Universitas Sumatera Utara
120
jumlah zona terlibat sebelum intervensi vit d * luas lesi pre thoraks
luas lesi pre thoraks
moderate
Count
Expected Count
Total
far advance
2
0
2
1.0
1.0
2.0
100.0%
0.0%
100.0%
18.2%
0.0%
9.5%
5
1
6
3.1
2.9
6.0
83.3%
16.7%
100.0%
45.5%
10.0%
28.6%
4
4
8
4.2
3.8
8.0
50.0%
50.0%
100.0%
36.4%
40.0%
38.1%
0
2
2
1.0
1.0
2.0
0.0%
100.0%
100.0%
0.0%
20.0%
9.5%
0
3
3
Dua Zona
Terlibat
% within jumlah zona terlibat
sebelum intervensi vit d
% within luas lesi pre thoraks
Count
Expected Count
Tiga Zona
Terlibat
% within jumlah zona terlibat
sebelum intervensi vit d
% within luas lesi pre thoraks
Count
jumlah zona
terlibat
Empat
Expected Count
sebelum
Zona
% within jumlah zona terlibat
intervensi vit d Terlibat
sebelum intervensi vit d
% within luas lesi pre thoraks
Count
Expected Count
Lima Zona
Terlibat
% within jumlah zona terlibat
sebelum intervensi vit d
% within luas lesi pre thoraks
Count
Expected Count
Enam Zona
% within jumlah zona terlibat
Terlibat
sebelum intervensi vit d
1.6
1.4
3.0
0.0%
100.0%
100.0%
% within luas lesi pre thoraks
0.0%
30.0%
14.3%
11
10
21
Count
Expected Count
Total
11.0
10.0
21.0
% within jumlah zona terlibat
sebelum intervensi vit d
52.4%
47.6%
100.0%
% within luas lesi pre thoraks
100.0%
100.0%
100.0%
Universitas Sumatera Utara
121
jumlah zona terlibat sesudah intervensi vit d * luasl lesi post thoraks
luasl lesi post thoraks
minimal
far advance
Count
2
0
0
2
Expected Count
.7
1.0
.4
2.0
100.0%
0.0%
0.0%
100.0%
28.6%
0.0%
0.0%
9.5%
3
1
1
5
1.7
2.4
1.0
5.0
60.0%
20.0%
20.0%
100.0%
42.9%
10.0%
25.0%
23.8%
2
5
0
7
2.3
3.3
1.3
7.0
28.6%
71.4%
0.0%
100.0%
28.6%
50.0%
0.0%
33.3%
0
4
1
5
1.7
2.4
1.0
5.0
0.0%
80.0%
20.0%
100.0%
0.0%
40.0%
25.0%
23.8%
Count
0
0
1
1
Expected Count
.3
.5
.2
1.0
0.0%
0.0%
100.0%
100.0%
0.0%
0.0%
25.0%
4.8%
0
0
1
1
.3
.5
.2
1.0
0.0%
0.0%
100.0%
100.0%
Satu Zona
% within jumlah zona terlibat
Terlibat
sesudah intervensi vit d
% within luasl lesi post
thoraks
Count
Expected Count
Dua Zona
% within jumlah zona terlibat
Terlibat
sesudah intervensi vit d
% within luasl lesi post
thoraks
Count
Expected Count
jumlah
Tiga Zona
% within jumlah zona terlibat
zona
Terlibat
sesudah intervensi vit d
terlibat
% within luasl lesi post
sesudah
thoraks
intervens
Count
i vit d
moderate
Total
Expected Count
Empat
Zona
Terlibat
% within jumlah zona terlibat
sesudah intervensi vit d
% within luasl lesi post
thoraks
Lima Zona
% within jumlah zona terlibat
Terlibat
sesudah intervensi vit d
% within luasl lesi post
thoraks
Count
Enam Zona Expected Count
Terlibat
% within jumlah zona terlibat
sesudah intervensi vit d
Universitas Sumatera Utara
122
% within luasl lesi post
thoraks
Count
Expected Count
% within jumlah zona terlibat
Total
sesudah intervensi vit d
% within luasl lesi post
thoraks
0.0%
0.0%
25.0%
4.8%
7
10
4
21
7.0
10.0
4.0
21.0
33.3%
47.6%
19.0%
100.0%
100.0%
100.0%
100.0%
100.0%
PADA KELOMPOK PLASEBO
jumlah zona terlibat sebelum intervensi vit d
Frequency
Percent
Valid Percent
Cumulative
Percent
Valid
Satu Zona Terlibat
1
4.8
4.8
4.8
Dua Zona Terlibat
5
23.8
23.8
28.6
Tiga Zona Terlibat
2
9.5
9.5
38.1
Empat Zona Terlibat
2
9.5
9.5
47.6
Lima Zona Terlibat
8
38.1
38.1
85.7
Enam Zona Terlibat
3
14.3
14.3
100.0
21
100.0
100.0
Total
jumlah zona terlibat sesudah intervensi vit d
Frequency
Percent
Valid Percent
Cumulative
Percent
Bersih
1
4.8
4.8
4.8
Satu Zona Terlibat
1
4.8
4.8
9.5
Dua Zona Terlibat
7
33.3
33.3
42.9
Tiga Zona Terlibat
2
9.5
9.5
52.4
Empat Zona Terlibat
2
9.5
9.5
61.9
Lima Zona Terlibat
6
28.6
28.6
90.5
Enam Zona Terlibat
2
9.5
9.5
100.0
21
100.0
100.0
Valid
Total
Universitas Sumatera Utara
123
KELOMPOK PLASEBO PADA POLIMORFISME
Crosstab SEBELUM PEMBERIAN PLASEBO
polimorfisme gen rvd
AA
Aa
Total
aa
Count
0
1
0
1
Expected Count
.1
.3
.5
1.0
0.0%
100.0%
0.0%
100.0%
0.0%
14.3%
0.0%
4.8%
Count
1
0
4
5
Expected Count
.7
1.7
2.6
5.0
20.0%
0.0%
80.0%
100.0%
33.3%
0.0%
36.4%
23.8%
Count
0
1
1
2
Expected Count
.3
.7
1.0
2.0
0.0%
50.0%
50.0%
100.0%
0.0%
14.3%
9.1%
9.5%
Count
2
0
0
2
Expected Count
.3
.7
1.0
2.0
100.0%
0.0%
0.0%
100.0%
66.7%
0.0%
0.0%
9.5%
0
4
4
8
1.1
2.7
4.2
8.0
0.0%
50.0%
50.0%
100.0%
0.0%
57.1%
36.4%
38.1%
Count
0
1
2
3
Expected Count
.4
1.0
1.6
3.0
0.0%
33.3%
66.7%
100.0%
0.0%
14.3%
18.2%
14.3%
3
7
11
21
Satu Zona
Terlibat
% within jumlah zona terlibat
sebelum intervensi vit d
% within polimorfisme gen rvd
Dua Zona
Terlibat
% within jumlah zona terlibat
sebelum intervensi vit d
% within polimorfisme gen rvd
Tiga Zona
Terlibat
% within jumlah zona terlibat
sebelum intervensi vit d
jumlah zona
% within polimorfisme gen rvd
terlibat sebelum
intervensi vit d
Empat Zona
Terlibat
% within jumlah zona terlibat
sebelum intervensi vit d
% within polimorfisme gen rvd
Count
Expected Count
Lima Zona
Terlibat
% within jumlah zona terlibat
sebelum intervensi vit d
% within polimorfisme gen rvd
Enam Zona
Terlibat
% within jumlah zona terlibat
sebelum intervensi vit d
% within polimorfisme gen rvd
Total
Count
Universitas Sumatera Utara
124
Expected Count
% within jumlah zona terlibat
sebelum intervensi vit d
% within polimorfisme gen rvd
3.0
7.0
11.0
21.0
14.3%
33.3%
52.4%
100.0%
100.0%
100.0%
100.0%
100.0%
Crosstab SESUDAH PEMBERIAN PLASEBO
polimorfisme gen rvd
AA
Aa
Total
aa
Count
0
0
1
1
Expected Count
.1
.3
.5
1.0
0.0%
0.0%
100.0%
100.0%
0.0%
0.0%
9.1%
4.8%
Count
0
1
0
1
Expected Count
.1
.3
.5
1.0
0.0%
100.0%
0.0%
100.0%
0.0%
14.3%
0.0%
4.8%
2
1
4
7
1.0
2.3
3.7
7.0
28.6%
14.3%
57.1%
100.0%
66.7%
14.3%
36.4%
33.3%
Count
0
1
1
2
Expected Count
.3
.7
1.0
2.0
0.0%
50.0%
50.0%
100.0%
0.0%
14.3%
9.1%
9.5%
% within jumlah zona
Bersih
terlibat sesudah intervensi
vit d
% within polimorfisme gen
rvd
Satu Zona
Terlibat
% within jumlah zona
terlibat sesudah intervensi
vit d
jumlah zona
% within polimorfisme gen
terlibat
rvd
sesudah
Count
intervensi vit d
Expected Count
Dua Zona
Terlibat
% within jumlah zona
terlibat sesudah intervensi
vit d
% within polimorfisme gen
rvd
Tiga Zona
Terlibat
% within jumlah zona
terlibat sesudah intervensi
vit d
% within polimorfisme gen
rvd
Universitas Sumatera Utara
125
Empat Zona
Terlibat
Count
1
1
0
2
Expected Count
.3
.7
1.0
2.0
50.0%
50.0%
0.0%
100.0%
33.3%
14.3%
0.0%
9.5%
Count
0
3
3
6
Expected Count
.9
2.0
3.1
6.0
0.0%
50.0%
50.0%
100.0%
0.0%
42.9%
27.3%
28.6%
Count
0
0
2
2
Expected Count
.3
.7
1.0
2.0
0.0%
0.0%
100.0%
100.0%
0.0%
0.0%
18.2%
9.5%
3
7
11
21
3.0
7.0
11.0
21.0
14.3%
33.3%
52.4%
100.0%
100.0%
100.0%
100.0%
100.0%
% within jumlah zona
terlibat sesudah intervensi
vit d
% within polimorfisme gen
rvd
Lima Zona
Terlibat
% within jumlah zona
terlibat sesudah intervensi
vit d
% within polimorfisme gen
rvd
Enam Zona
Terlibat
% within jumlah zona
terlibat sesudah intervensi
vit d
% within polimorfisme gen
rvd
Count
Expected Count
% within jumlah zona
Total
terlibat sesudah intervensi
vit d
% within polimorfisme gen
rvd
Universitas Sumatera Utara
126
JUMLAH ZONA BERDASARKAN LESI PRE PADA PLASEBO
jumlah zona terlibat sebelum intervensi vit d pada kelompok plasebo * luas lesi pre thoraks
Crosstabulation
luas lesi pre thoraks
minimal
Satu Zona
Terlibat
moderate
Total
far advance
Count
1
0
0
1
Expected Count
.0
.5
.5
1.0
100.0%
0.0%
0.0%
100.0%
100.0%
0.0%
0.0%
4.8%
Count
0
5
0
5
Expected Count
.2
2.4
2.4
5.0
0.0%
100.0%
0.0%
100.0%
0.0%
50.0%
0.0%
23.8%
Count
0
1
1
2
Expected Count
.1
1.0
1.0
2.0
0.0%
50.0%
50.0%
100.0%
0.0%
10.0%
10.0%
9.5%
Count
0
1
1
2
Expected Count
.1
1.0
1.0
2.0
0.0%
50.0%
50.0%
100.0%
0.0%
10.0%
10.0%
9.5%
% within jumlah zona
terlibat sebelum
intervensi vit d
% within luas lesi pre
thoraks
Dua Zona
Terlibat
% within jumlah zona
terlibat sebelum
intervensi vit d
% within luas lesi pre
thoraks
jumlah zona
terlibat sebelum
intervensi vit d
Tiga Zona
Terlibat
% within jumlah zona
terlibat sebelum
intervensi vit d
% within luas lesi pre
thoraks
Empat Zona
Terlibat
% within jumlah zona
terlibat sebelum
intervensi vit d
% within luas lesi pre
thoraks
Lima Zona
Count
0
3
5
8
Terlibat
Expected Count
.4
3.8
3.8
8.0
Universitas Sumatera Utara
127
% within jumlah zona
terlibat sebelum
0.0%
37.5%
62.5%
100.0%
0.0%
30.0%
50.0%
38.1%
Count
0
0
3
3
Expected Count
.1
1.4
1.4
3.0
0.0%
0.0%
100.0%
100.0%
0.0%
0.0%
30.0%
14.3%
1
10
10
21
1.0
10.0
10.0
21.0
4.8%
47.6%
47.6%
100.0%
100.0%
100.0%
100.0%
100.0%
intervensi vit d
% within luas lesi pre
thoraks
Enam Zona
Terlibat
% within jumlah zona
terlibat sebelum
intervensi vit d
% within luas lesi pre
thoraks
Count
Expected Count
% within jumlah zona
Total
terlibat sebelum
intervensi vit d
% within luas lesi pre
thoraks
Universitas Sumatera Utara
128
jumlah zona terlibat sesudah intervensi PLASEBO * luasl lesi post thoraks Crosstabulation
luasl lesi post thoraks
bersih
minimal
moderate
Total
far advance
Count
1
0
0
0
1
Expected Count
.0
.0
.7
.2
1.0
100.0%
0.0%
0.0%
0.0%
100.0%
100.0%
0.0%
0.0%
0.0%
4.8%
Count
0
1
0
0
1
Expected Count
.0
.0
.7
.2
1.0
0.0%
100.0%
0.0%
0.0%
100.0%
0.0%
100.0%
0.0%
0.0%
4.8%
% within jumlah zona
Bersih
terlibat sesudah
intervensi vit d
% within luasl lesi post
thoraks
Satu Zona
Terlibat
% within jumlah zona
terlibat sesudah
intervensi vit d
% within luasl lesi post
thoraks
jumlah zona
Count
0
0
7
0
7
terlibat
Expected Count
.3
.3
4.7
1.7
7.0
0.0%
0.0%
100.0%
0.0%
100.0%
0.0%
0.0%
50.0%
0.0%
33.3%
Count
0
0
2
0
2
Expected Count
.1
.1
1.3
.5
2.0
0.0%
0.0%
100.0%
0.0%
100.0%
0.0%
0.0%
14.3%
0.0%
9.5%
Count
0
0
2
0
2
Expected Count
.1
.1
1.3
.5
2.0
0.0%
0.0%
100.0%
0.0%
100.0%
sesudah
intervensi
vit d
Dua Zona
Terlibat
% within jumlah zona
terlibat sesudah
intervensi vit d
% within luasl lesi post
thoraks
Tiga Zona
Terlibat
% within jumlah zona
terlibat sesudah
intervensi vit d
% within luasl lesi post
thoraks
Empat Zona
Terlibat
% within jumlah zona
terlibat sesudah
intervensi vit d
Universitas Sumatera Utara
129
% within luasl lesi post
0.0%
0.0%
14.3%
0.0%
9.5%
Count
0
0
2
4
6
Expected Count
.3
.3
4.0
1.4
6.0
0.0%
0.0%
33.3%
66.7%
100.0%
0.0%
0.0%
14.3%
80.0%
28.6%
Count
0
0
1
1
2
Expected Count
.1
.1
1.3
.5
2.0
0.0%
0.0%
50.0%
50.0%
100.0%
0.0%
0.0%
7.1%
20.0%
9.5%
1
1
14
5
21
1.0
1.0
14.0
5.0
21.0
4.8%
4.8%
66.7%
23.8%
100.0%
100.0%
100.0%
100.0%
100.0%
100.0%
thoraks
Lima Zona
Terlibat
% within jumlah zona
terlibat sesudah
intervensi vit d
% within luasl lesi post
thoraks
Enam Zona
Terlibat
% within jumlah zona
terlibat sesudah
intervensi vit d
% within luasl lesi post
thoraks
Count
Expected Count
% within jumlah zona
Total
terlibat sesudah
intervensi vit d
% within luasl lesi post
thoraks
Universitas Sumatera Utara
130
UJI PERBEDAAN HASIL FOTO THORAKS PADA KELOMPOK VITAMIN D
Paired Samples Test
Paired Differences
Mean
t
Std.
Std. Error
95% Confidence
Deviation
Mean
Interval of the
df
Sig. (2tailed)
Difference
Lower
Upper
jumlah zona
terlibat sebelum
Pair 1
intervensi vit d
- jumlah zona
.857
.727
.159
.526
1.188
5.403
20
.000
terlibat sesudah
intervensi vit d
Paired Samples Statistics
Mean
jumlah zona terlibat sebelum
intervensi vit d
N
Std. Deviation
Std. Error Mean
3.90
21
1.179
.257
3.05
21
1.244
.271
Pair 1
jumlah zona terlibat sesudah
intervensi vit d
Uji Beda keterlibatan zona
JUMLAH ZONA TERLIBAT
SEBELUM INTERVENSI
VIT D PADA KELOMPOK
VITAMIN D
Paired Differences
Mean
t
Std.
Std.
95% Confidence Interval
Deviatio
Error
of the Difference
n
Mean
Lower
df
Sig. (2tailed)
Upper
jumlah zona
terlibat sebelum
Pair 1
intervensi vit d jumlah zona
.571
.926
.202
.150
.993
2.828
20
terlibat sesudah
intervensi vit d
Universitas Sumatera Utara
.010
131
7. PERBAIKAN FOTO TORAKS
Crosstab kelompok vit d sesudah
perbaikan
tidak ada
satu
dua
perbaikan
perbaikan
perbaikan
Count
0
2
0
2
Expected Count
.7
1.0
.4
2.0
0.0%
100.0%
0.0%
100.0%
% within perbaikan
0.0%
20.0%
0.0%
9.5%
% of Total
0.0%
9.5%
0.0%
9.5%
0
3
2
5
1.7
2.4
1.0
5.0
0.0%
60.0%
40.0%
100.0%
% within perbaikan
0.0%
30.0%
50.0%
23.8%
% of Total
0.0%
14.3%
9.5%
23.8%
3
3
1
7
2.3
3.3
1.3
7.0
42.9%
42.9%
14.3%
100.0%
% within perbaikan
42.9%
30.0%
25.0%
33.3%
% of Total
14.3%
14.3%
4.8%
33.3%
3
1
1
5
1.7
2.4
1.0
5.0
60.0%
20.0%
20.0%
100.0%
% within perbaikan
42.9%
10.0%
25.0%
23.8%
% of Total
14.3%
4.8%
4.8%
23.8%
Count
0
1
0
1
Expected Count
.3
.5
.2
1.0
0.0%
100.0%
0.0%
100.0%
% within perbaikan
0.0%
10.0%
0.0%
4.8%
% of Total
0.0%
4.8%
0.0%
4.8%
1
0
0
1
Satu Zona
% within jumlah zona terlibat
Terlibat
sesudah intervensi vit d
Count
Expected Count
Dua Zona
% within jumlah zona terlibat
Terlibat
sesudah intervensi vit d
Count
jumlah
zona
terlibat
Total
Expected Count
Tiga Zona
% within jumlah zona terlibat
Terlibat
sesudah intervensi vit d
sesudah
intervensi
vit d
Count
Expected Count
Empat Zona
% within jumlah zona terlibat
Terlibat
sesudah intervensi vit d
Lima Zona
% within jumlah zona terlibat
Terlibat
sesudah intervensi vit d
Enam Zona
Count
Universitas Sumatera Utara
132
Terlibat
Expected Count
% within jumlah zona terlibat
sesudah intervensi vit d
% within perbaikan
% of Total
Count
Expected Count
% within jumlah zona terlibat
Total
sesudah intervensi vit d
% within perbaikan
% of Total
.3
.5
.2
1.0
100.0%
0.0%
0.0%
100.0%
14.3%
0.0%
0.0%
4.8%
4.8%
0.0%
0.0%
4.8%
7
10
4
21
7.0
10.0
4.0
21.0
33.3%
47.6%
19.0%
100.0%
100.0%
100.0%
100.0%
100.0%
33.3%
47.6%
19.0%
100.0%
Crosstab pada kelompok plasebo sesudah
perbaikan
Total
tidak ada
satu
dua
tiga
perbaikan
perbaikan
perbaika
perbaikan
n
Bersih
jumlah zona
Count
0
0
0
1
1
Expected Count
.6
.1
.2
.0
1.0
0.0%
0.0%
0.0%
100.0%
100.0%
% within perbaikan
0.0%
0.0%
0.0%
100.0%
4.8%
% of Total
0.0%
0.0%
0.0%
4.8%
4.8%
Count
1
0
0
0
1
Expected Count
.6
.1
.2
.0
1.0
100.0%
0.0%
0.0%
0.0%
100.0%
% within jumlah zona terlibat
sesudah intervensi vit d
terlibat
Satu Zona
% within jumlah zona terlibat
sesudah
Terlibat
sesudah intervensi vit d
intervensi vit
% within perbaikan
7.7%
0.0%
0.0%
0.0%
4.8%
d
% of Total
4.8%
0.0%
0.0%
0.0%
4.8%
4
1
2
0
7
4.3
1.0
1.3
.3
7.0
57.1%
14.3%
28.6%
0.0%
100.0%
% within perbaikan
30.8%
33.3%
50.0%
0.0%
33.3%
% of Total
19.0%
4.8%
9.5%
0.0%
33.3%
0
0
2
0
2
Count
Expected Count
Dua Zona
% within jumlah zona terlibat
Terlibat
sesudah intervensi vit d
Tiga Zona
Count
Universitas Sumatera Utara
133
Terlibat
Expected Count
1.2
.3
.4
.1
2.0
0.0%
0.0%
100.0%
0.0%
100.0%
% within perbaikan
0.0%
0.0%
50.0%
0.0%
9.5%
% of Total
0.0%
0.0%
9.5%
0.0%
9.5%
1
1
0
0
2
1.2
.3
.4
.1
2.0
50.0%
50.0%
0.0%
0.0%
100.0%
% within perbaikan
7.7%
33.3%
0.0%
0.0%
9.5%
% of Total
4.8%
4.8%
0.0%
0.0%
9.5%
5
1
0
0
6
3.7
.9
1.1
.3
6.0
83.3%
16.7%
0.0%
0.0%
100.0%
% within perbaikan
38.5%
33.3%
0.0%
0.0%
28.6%
% of Total
23.8%
4.8%
0.0%
0.0%
28.6%
2
0
0
0
2
1.2
.3
.4
.1
2.0
100.0%
0.0%
0.0%
0.0%
100.0%
15.4%
0.0%
0.0%
0.0%
9.5%
9.5%
0.0%
0.0%
0.0%
9.5%
13
3
4
1
21
13.0
3.0
4.0
1.0
21.0
61.9%
14.3%
19.0%
4.8%
100.0%
100.0%
100.0%
100.0%
100.0%
100.0%
61.9%
14.3%
19.0%
4.8%
100.0%
% within jumlah zona terlibat
sesudah intervensi vit d
Count
Expected Count
Empat
Zona
Terlibat
% within jumlah zona terlibat
sesudah intervensi vit d
Count
Expected Count
Lima Zona
% within jumlah zona terlibat
Terlibat
sesudah intervensi vit d
Count
Expected Count
Enam Zona % within jumlah zona terlibat
Terlibat
sesudah intervensi vit d
% within perbaikan
% of Total
Count
Expected Count
Total
% within jumlah zona terlibat
sesudah intervensi vit d
% within perbaikan
% of Total
Universitas Sumatera Utara
134
8. PERBEDAAN JUMLH ZONA BERDASARKAN POLIMORFISME
JUMLAH ZONA TERLIBAT PRE PADA KELOMPOK VIT D
polimorfisme gen rvd
AA
Dua
Zona
Terlibat
0
1
1
2
Expected Count
.1
.8
1.1
2.0
0.0%
50.0%
50.0%
100.0%
0.0%
12.5%
8.3%
9.5%
0.0%
4.8%
4.8%
9.5%
Count
0
1
5
6
Expected Count
.3
2.3
3.4
6.0
0.0%
16.7%
83.3%
100.0%
0.0%
12.5%
41.7%
28.6%
0.0%
4.8%
23.8%
28.6%
Count
0
4
4
8
Expected Count
.4
3.0
4.6
8.0
0.0%
50.0%
50.0%
100.0%
0.0%
50.0%
33.3%
38.1%
0.0%
19.0%
19.0%
38.1%
Count
0
2
0
2
Expected Count
.1
.8
1.1
2.0
0.0%
100.0%
0.0%
100.0%
0.0%
25.0%
0.0%
9.5%
0.0%
9.5%
0.0%
9.5%
% within jumlah zona
terlibat sebelum intervensi
vit d
rvd
% of Total
Zona
Terlibat
% within jumlah zona
terlibat sebelum intervensi
vit d
% within polimorfisme gen
rvd
jumlah zona
aa
Count
% within polimorfisme gen
Tiga
Aa
Total
% of Total
terlibat sebelum
intervensi vit d
Empat
Zona
Terlibat
% within jumlah zona
terlibat sebelum intervensi
vit d
% within polimorfisme gen
rvd
% of Total
Lima
Zona
Terlibat
% within jumlah zona
terlibat sebelum intervensi
vit d
% within polimorfisme gen
rvd
% of Total
Universitas Sumatera Utara
135
Enam
Zona
Terlibat
Count
1
0
2
3
Expected Count
.1
1.1
1.7
3.0
33.3%
0.0%
66.7%
100.0%
100.0%
0.0%
16.7%
14.3%
4.8%
0.0%
9.5%
14.3%
1
8
12
21
1.0
8.0
12.0
21.0
4.8%
38.1%
57.1%
100.0%
100.0%
100.0%
100.0%
100.0%
4.8%
38.1%
57.1%
100.0%
% within jumlah zona
terlibat sebelum intervensi
vit d
% within polimorfisme gen
rvd
% of Total
Count
Expected Count
% within jumlah zona
terlibat sebelum intervensi
Total
vit d
% within polimorfisme gen
rvd
% of Total
JUMLAH ZONA TERLIBAT PRE PADA KELOMPOK VIT D
polimorfisme gen rvd
AA
aa
Count
0
1
1
2
Expected Count
.1
.8
1.1
2.0
0.0%
50.0%
50.0%
100.0%
% within polimorfisme gen rvd
0.0%
12.5%
8.3%
9.5%
% of Total
0.0%
4.8%
4.8%
9.5%
Count
0
1
5
6
Expected Count
.3
2.3
3.4
6.0
0.0%
16.7%
83.3%
100.0%
% within polimorfisme gen rvd
0.0%
12.5%
41.7%
28.6%
% of Total
0.0%
4.8%
23.8%
28.6%
Count
0
4
4
8
Empat Zona
Expected Count
.4
3.0
4.6
8.0
Terlibat
% within jumlah zona terlibat
0.0%
50.0%
50.0%
100.0%
Dua Zona
% within jumlah zona terlibat
Terlibat
sebelum intervensi vit d
jumlah zona
terlibat sebelum
intervensi vit d
Aa
Total
Tiga Zona
% within jumlah zona terlibat
Terlibat
sebelum intervensi vit d
sebelum intervensi vit d
Universitas Sumatera Utara
136
% within polimorfisme gen rvd
0.0%
50.0%
33.3%
38.1%
% of Total
0.0%
19.0%
19.0%
38.1%
Count
0
2
0
2
Expected Count
.1
.8
1.1
2.0
0.0%
100.0%
0.0%
100.0%
% within polimorfisme gen rvd
0.0%
25.0%
0.0%
9.5%
% of Total
0.0%
9.5%
0.0%
9.5%
Count
1
0
2
3
Expected Count
.1
1.1
1.7
3.0
33.3%
0.0%
66.7%
100.0%
100.0%
0.0%
16.7%
14.3%
4.8%
0.0%
9.5%
14.3%
1
8
12
21
1.0
8.0
12.0
21.0
4.8%
38.1%
57.1%
100.0%
100.0%
100.0%
100.0%
100.0%
4.8%
38.1%
57.1%
100.0%
Lima Zona
% within jumlah zona terlibat
Terlibat
sebelum intervensi vit d
Enam Zona
% within jumlah zona terlibat
Terlibat
sebelum intervensi vit d
% within polimorfisme gen rvd
% of Total
Count
Expected Count
% within jumlah zona terlibat
Total
sebelum intervensi vit d
% within polimorfisme gen rvd
% of Total
PADA KELOMPOK PLASEBO
SEBELUM PADA KELOMPOK PLASEBO
polimorfisme gen rvd
AA
Aa
Total
aa
Count
0
1
0
1
Expected Count
.1
.3
.5
1.0
0.0%
100.0%
0.0%
100.0%
0.0%
14.3%
0.0%
4.8%
0.0%
4.8%
0.0%
4.8%
% within jumlah zona
jumlah zona
Satu Zona
terlibat sebelum
terlibat
Terlibat
intervensi vit d
sebelum
% within polimorfisme
intervensi vit d
gen rvd
% of Total
Dua Zona
Count
1
0
4
5
Terlibat
Expected Count
.7
1.7
2.6
5.0
Universitas Sumatera Utara
137
% within jumlah zona
terlibat sebelum
20.0%
0.0%
80.0%
100.0%
33.3%
0.0%
36.4%
23.8%
4.8%
0.0%
19.0%
23.8%
Count
0
1
1
2
Expected Count
.3
.7
1.0
2.0
0.0%
50.0%
50.0%
100.0%
0.0%
14.3%
9.1%
9.5%
0.0%
4.8%
4.8%
9.5%
Count
2
0
0
2
Expected Count
.3
.7
1.0
2.0
100.0%
0.0%
0.0%
100.0%
66.7%
0.0%
0.0%
9.5%
9.5%
0.0%
0.0%
9.5%
0
4
4
8
1.1
2.7
4.2
8.0
0.0%
50.0%
50.0%
100.0%
0.0%
57.1%
36.4%
38.1%
0.0%
19.0%
19.0%
38.1%
Count
0
1
2
3
Expected Count
.4
1.0
1.6
3.0
0.0%
33.3%
66.7%
100.0%
0.0%
14.3%
18.2%
14.3%
intervensi vit d
% within polimorfisme
gen rvd
% of Total
% within jumlah zona
Tiga Zona
terlibat sebelum
Terlibat
intervensi vit d
% within polimorfisme
gen rvd
% of Total
% within jumlah zona
Empat Zona
terlibat sebelum
Terlibat
intervensi vit d
% within polimorfisme
gen rvd
% of Total
Count
Expected Count
% within jumlah zona
Lima Zona
terlibat sebelum
Terlibat
intervensi vit d
% within polimorfisme
gen rvd
% of Total
Enam Zona
Terlibat
% within jumlah zona
terlibat sebelum
intervensi vit d
% within polimorfisme
gen rvd
Universitas Sumatera Utara
138
% of Total
0.0%
4.8%
9.5%
14.3%
3
7
11
21
3.0
7.0
11.0
21.0
14.3%
33.3%
52.4%
100.0%
100.0%
100.0%
100.0%
100.0%
14.3%
33.3%
52.4%
100.0%
Count
Expected Count
% within jumlah zona
terlibat sebelum
Total
intervensi vit d
% within polimorfisme
gen rvd
% of Total
SEBELUM PADA KELOMPOK PLASEBO
polimorfisme gen rvd
AA
Aa
Total
aa
Count
0
0
2
2
Expected Count
.3
.7
1.0
2.0
0.0%
0.0%
100.0%
100.0%
0.0%
0.0%
18.2%
9.5%
0.0%
0.0%
9.5%
9.5%
Count
0
1
0
1
Expected Count
.1
.3
.5
1.0
0.0%
100.0%
0.0%
100.0%
0.0%
14.3%
0.0%
4.8%
0.0%
4.8%
0.0%
4.8%
Count
2
1
3
6
Expected Count
.9
2.0
3.1
6.0
33.3%
16.7%
50.0%
100.0%
66.7%
14.3%
27.3%
28.6%
9.5%
4.8%
14.3%
28.6%
% within jumlah zona
Bersih
terlibat sesudah intervensi
vit d
% within polimorfisme gen
rvd
% of Total
jumlah zona
terlibat sesudah
intervensi vit d
% within jumlah zona
Satu Zona
terlibat sesudah intervensi
Terlibat
vit d
% within polimorfisme gen
rvd
% of Total
% within jumlah zona
Dua Zona
terlibat sesudah intervensi
Terlibat
vit d
% within polimorfisme gen
rvd
% of Total
Universitas Sumatera Utara
139
Count
0
1
1
2
Expected Count
.3
.7
1.0
2.0
0.0%
50.0%
50.0%
100.0%
0.0%
14.3%
9.1%
9.5%
0.0%
4.8%
4.8%
9.5%
Count
1
1
0
2
Expected Count
.3
.7
1.0
2.0
50.0%
50.0%
0.0%
100.0%
33.3%
14.3%
0.0%
9.5%
4.8%
4.8%
0.0%
9.5%
Count
0
3
3
6
Expected Count
.9
2.0
3.1
6.0
0.0%
50.0%
50.0%
100.0%
0.0%
42.9%
27.3%
28.6%
0.0%
14.3%
14.3%
28.6%
Count
0
0
2
2
Expected Count
.3
.7
1.0
2.0
0.0%
0.0%
100.0%
100.0%
0.0%
0.0%
18.2%
9.5%
0.0%
0.0%
9.5%
9.5%
3
7
11
21
3.0
7.0
11.0
21.0
14.3%
33.3%
52.4%
100.0%
% within jumlah zona
Tiga Zona
terlibat sesudah intervensi
Terlibat
vit d
% within polimorfisme gen
rvd
% of Total
% within jumlah zona
Empat Zona
terlibat sesudah intervensi
Terlibat
vit d
% within polimorfisme gen
rvd
% of Total
% within jumlah zona
Lima Zona
terlibat sesudah intervensi
Terlibat
vit d
% within polimorfisme gen
rvd
% of Total
% within jumlah zona
Enam Zona
terlibat sesudah intervensi
Terlibat
vit d
% within polimorfisme gen
rvd
% of Total
Count
Expected Count
Total
% within jumlah zona
terlibat sesudah intervensi
vit d
Universitas Sumatera Utara
140
% within polimorfisme gen
rvd
% of Total
100.0%
100.0%
100.0%
100.0%
14.3%
33.3%
52.4%
100.0%
9. PERBAIKAN TERHADAP POLIMORFISME
polimorfisme gen rvd * luas lesi pre thoraks Crosstabulation
luas lesi pre thoraks
moderate
Count
% within polimorfisme gen
rvd
Total
far advance
0
1
1
0.0%
100.0%
100.0%
0.0%
10.0%
4.8%
0.0%
4.8%
4.8%
5
3
8
62.5%
37.5%
100.0%
45.5%
30.0%
38.1%
23.8%
14.3%
38.1%
6
6
12
50.0%
50.0%
100.0%
54.5%
60.0%
57.1%
28.6%
28.6%
57.1%
11
10
21
52.4%
47.6%
100.0%
100.0%
100.0%
100.0%
52.4%
47.6%
100.0%
AA
% within luas lesi pre
thoraks
% of Total
Count
% within polimorfisme gen
rvd
polimorfisme gen rvd
Aa
% within luas lesi pre
thoraks
% of Total
Count
% within polimorfisme gen
rvd
aa
% within luas lesi pre
thoraks
% of Total
Count
% within polimorfisme gen
rvd
Total
% within luas lesi pre
thoraks
% of Total
polimorfisme gen rvd * luasl lesi post thoraks Crosstabulation
Universitas Sumatera Utara
141
luasl lesi post thoraks
minimal
Count
% within polimorfisme gen
rvd
moderate
Total
far advance
0
1
0
1
0.0%
100.0%
0.0%
100.0%
0.0%
10.0%
0.0%
4.8%
0.0%
4.8%
0.0%
4.8%
2
5
1
8
25.0%
62.5%
12.5%
100.0%
28.6%
50.0%
25.0%
38.1%
9.5%
23.8%
4.8%
38.1%
5
4
3
12
41.7%
33.3%
25.0%
100.0%
71.4%
40.0%
75.0%
57.1%
23.8%
19.0%
14.3%
57.1%
7
10
4
21
33.3%
47.6%
19.0%
100.0%
100.0%
100.0%
100.0%
100.0%
33.3%
47.6%
19.0%
100.0%
AA
% within luasl lesi post
thoraks
% of Total
Count
% within polimorfisme gen
rvd
polimorfisme gen rvd
Aa
% within luasl lesi post
thoraks
% of Total
Count
% within polimorfisme gen
rvd
aa
% within luasl lesi post
thoraks
% of Total
Count
% within polimorfisme gen
rvd
Total
% within luasl lesi post
thoraks
% of Total
polimorfisme gen rvd * luas lesi pre thoraks Crosstabulation
luas lesi pre thoraks
minimal
Count
AA
far advance
0
2
1
3
0.0%
66.7%
33.3%
100.0%
% within luas lesi pre thoraks
0.0%
20.0%
10.0%
14.3%
% of Total
0.0%
9.5%
4.8%
14.3%
% within polimorfisme gen
polimorfisme gen rvd
moderate
Total
rvd
Universitas Sumatera Utara
142
Count
1
3
3
7
14.3%
42.9%
42.9%
100.0%
100.0%
30.0%
30.0%
33.3%
4.8%
14.3%
14.3%
33.3%
0
5
6
11
0.0%
45.5%
54.5%
100.0%
% within luas lesi pre thoraks
0.0%
50.0%
60.0%
52.4%
% of Total
0.0%
23.8%
28.6%
52.4%
1
10
10
21
4.8%
47.6%
47.6%
100.0%
100.0%
100.0%
100.0%
100.0%
4.8%
47.6%
47.6%
100.0%
% within polimorfisme gen
Aa
rvd
% within luas lesi pre thoraks
% of Total
Count
% within polimorfisme gen
aa
rvd
Count
% within polimorfisme gen
rvd
Total
% within luas lesi pre thoraks
% of Total
polimorfisme gen rvd * luasl lesi post thoraks Crosstabulation
luasl lesi post thoraks
bersih
Count
% within polimorfisme gen rvd
AA
% within luasl lesi post
thoraks
% of Total
Count
% within polimorfisme gen rvd
polimorfisme
gen rvd
Aa
% within luasl lesi post
thoraks
% of Total
Count
% within polimorfisme gen rvd
aa
% within luasl lesi post
thoraks
% of Total
Total
Count
minimal
moderate
Total
far advance
0
0
3
0
3
0.0%
0.0%
100.0%
0.0%
100.0%
0.0%
0.0%
21.4%
0.0%
14.3%
0.0%
0.0%
14.3%
0.0%
14.3%
0
1
4
2
7
0.0%
14.3%
57.1%
28.6%
100.0%
0.0%
100.0%
28.6%
40.0%
33.3%
0.0%
4.8%
19.0%
9.5%
33.3%
1
0
7
3
11
9.1%
0.0%
63.6%
27.3%
100.0%
100.0%
0.0%
50.0%
60.0%
52.4%
4.8%
0.0%
33.3%
14.3%
52.4%
1
1
14
5
21
Universitas Sumatera Utara
143
% within polimorfisme gen rvd
% within luasl lesi post
thoraks
% of Total
4.8%
4.8%
66.7%
23.8%
100.0%
100.0%
100.0%
100.0%
100.0%
100.0%
4.8%
4.8%
66.7%
23.8%
100.0%
10. HUBUNGAN FOTO THORAKS DENGAN POLIMORFISME
perbaikan pada kelompok yang diberikan vitamin D * Polimorfis Crosstabulation
Polimorfis
AA+Aa
perbaikan pada kedua
tidak ada perbaikan foto
Count
thorax
Expected Count
kelompok
Total
aa
3
4
7
3.0
4.0
7.0
6
8
14
6.0
8.0
14.0
9
12
21
9.0
12.0
21.0
Count
ada perbaikan foto thorax
Expected Count
Count
Total
Expected Count
Chi-Square Tests
Value
Pearson Chi-Square
Continuity Correction
df
Likelihood Ratio
Exact Sig. (2-
Exact Sig. (1-
sided)
sided)
sided)
a
1
1.000
.000
1
1.000
.000
1
1.000
.000
b
Asymp. Sig. (2-
Fisher's Exact Test
Linear-by-Linear Association
N of Valid Cases
1.000
.000
1
.681
1.000
21
a. 2 cells (50.0%) have expected count less than 5. The minimum expected count is 3.00.
b. Computed only for a 2x2 table
Universitas Sumatera Utara
144
perbaikan pada kedua kelompok * Polimorfis Crosstabulation
Polimorfis
AA+Aa
perbaikan pada kedua
tidak ada perbaikan foto
Count
thorax
Expected Count
kelompok
Total
aa
5
8
13
6.2
6.8
13.0
5
3
8
Expected Count
3.8
4.2
8.0
Count
10
11
21
10.0
11.0
21.0
Count
ada perbaikan foto thorax
Total
Expected Count
Chi-Square Tests
Value
Pearson Chi-Square
Continuity Correction
df
Likelihood Ratio
Exact Sig. (2-
Exact Sig. (1-
sided)
sided)
sided)
a
1
.284
.386
1
.534
1.156
1
.282
1.147
b
Asymp. Sig. (2-
Fisher's Exact Test
Linear-by-Linear Association
N of Valid Cases
.387
1.093
1
.268
.296
21
a. 2 cells (50.0%) have expected count less than 5. The minimum expected count is 3.81.
b. Computed only for a 2x2 table
Universitas Sumatera Utara
145
Universitas Sumatera Utara
146
Universitas Sumatera Utara