Formulasi Sediaan Gel Ekstrak Etanol Daun Teh Hijau (Camellia sinensis (L.) Kuntze) dan Uji Efektivitas Penyembuhan Luka Sayat pada Tikus Putih

(1)

(2)

(3)

Lampiran 3. Gambar Alat-alat

Jangka sorong

Alat destilasi

Viskometer Brookfield


(4)

(5)

(6)

Lampiran 5. Gambar daun segar teh dan simplisia daun teh (

Camellia

sinensis

(L.) Kuntze)


(7)

Lampiran 6. Gambar serbuk simplisia dan ekstrak etanol daun teh hijau


(8)

Lampiran 7.

Perhitungan penetapan kadar abu total dari ekstrak etanol daun

teh hijau

=

2,006%

No

Berat Sampel (g)

Berat Abu (g)

1

2

3

2,0379

2,0204

2,0174

0,0398

0,0400

0,0423


(9)

Lampiran 8. Perhitungan penetapan kadar abu tidak larut asam dari ekstrak

etanol daun teh hijau

=

0,42%

No

Berat Sampel (g)

Berat Abu (g)

1

2

3

2,0379

2,0204

2,0174

0,0083

0,01

0,0075


(10)

Lampiran 9. Perhitungan penetapan kadar air dari ekstrak etanol daun teh hijau

=

15,98%

No

Berat Sampel (g)

Volume Awal (mL)

Volume Akhir (mL)

1

2

3

5,003

5,004

5,001

1,8

2,5

3,4

2,5

3,4

4,2


(11)

Lampiran 10. Bagan pembuatan ekstrak etanol daun teh hijau

Daun teh kering 520

Ditimbang berat keringnya

Dikeringkan menggunakan lemari pengering

1,65 kg Daun teh hijau

Dicuci dari pengotor sampai bersih Ditiriskan

Ditimbang berat basahnya

Dihaluskan dengan blender

Disimpan dalam wadah tertutup sebelum digunakan

400 gram serbuk simplisia

Dimasukkan kedalam wadah

Ditambahkan 3000 ml etamol 70% hingga serbuk terendam

Dibiarkan selama 5 hari terlindung dari cahaya, sambil sesekali diaduk

Disaring

Ampas Maserat I

Dimaserasi menggunakan etanol 70% sebanyak 1000 ml

Dibiarka selama dua hari dan terhindar dari cahaya

Diendaptuangkan Disaring

Maserat II

Dipekatkan dengan rotary evaforator

Ekstrak cair

Dikeringkan dengan freeze dryer


(12)

Lampiran 11. Bagan kerja penelitian

Ekstrak kental

Uji aktivitas terhadap

Penyembuhan Luka pada tikus

konsentrasi 1%, 3%, 5%

Diformulasi dengan basis gel

Sediaan uji

(Penyembuhan Luka

Sayat) konsentrasi

1%, 3%, 5%

Diuji aktivitas

penyembuhan luka

Diuji stabilitas fisik

Histopatologi

Bentuk, warna, bau,

homogenitas, pH,


(13)

Lampiran 12. Gambar sediaan

Masing-masing formula gel pada minggu ke-0


(14)

Lampiran 13

. Gambar homogenitas sediaan masing-masing formula


(15)

Lampiran 14. Gambar perubahan diameter luka sayat kelompok kontrol negatif

(Basis gel)

Hari Ke-20

Hari Ke-21

Hari Ke-22

Hari Ke-23

Hari Ke-16

Hari Ke-17

Hari Ke-18

Hari Ke-19

Hari Ke-12

Hari Ke-13

Hari Ke-14

Hari Ke-15

Hari Ke-8

Hari Ke-9

Hari Ke-10

Hari Ke-11

Hari Ke-4

Hari Ke-5

Hari Ke-6

Hari Ke-7


(16)

Lampiran 15. Gambar perubahan diameter luka sayat kelompok ekstrak etanol

daun teh hijau 1%

Hari Ke-0

Hari Ke-1

Hari Ke-2

Hari Ke-3

Hari Ke-4

Hari Ke-5

Hari Ke-6

Hari Ke-7

Hari Ke-8

Hari Ke-9

Hari Ke-10

Hari Ke-11

Hari Ke-12

Hari Ke-13

Hari Ke-14

Hari Ke-15

Hari Ke-16

Hari Ke-17

Hari Ke-18

Hari Ke-19


(17)

Lampiran 16. Gambar perubahan diameter luka sayat kelompok ekstrak etanol

daun teh hijau 3%

Hari Ke-0

Hari Ke-1

Hari Ke-2

Hari Ke-3

Hari Ke-4

Hari Ke-5

Hari Ke-6

Hari Ke-7

Hari Ke-8

Hari Ke-9

Hari Ke-10

Hari Ke-11

Hari Ke-12

Hari Ke-13

Hari Ke-14

Hari Ke-15

Hari Ke-16

Hari Ke-17

Hari Ke-18

Hari Ke-19


(18)

Lampiran 17. Gambar perubahan diameter luka sayat kelompok ekstrak etanol

daun teh hijau 5%

Hari Ke-0

Hari Ke-1

Hari Ke-2

Hari Ke-3

Hari Ke-4

Hari Ke-5

Hari Ke-6

Hari Ke-7

Hari Ke-8

Hari Ke-9

Hari Ke-10

Hari Ke-11

Hari Ke-12

Hari Ke-13

Hari Ke-14

Hari Ke-15

Hari Ke-16

Hari Ke-17

Hari Ke-18

Hari Ke-19


(19)

Lampiran 18. Gambar perubahan diameter luka sayat kelompok Betadine salep

Hari Ke-0

Hari Ke-1

Hari Ke-2

Hari Ke-3

Hari Ke-4

Hari Ke-5

Hari Ke-6

Hari Ke-7

Hari Ke-8

Hari Ke-9

Hari Ke-10

Hari Ke-11

Hari Ke-12

Hari Ke-13

Hari Ke-14

Hari Ke-15


(20)

Lampiran 20. Perhitungan persentase pengurangan diameter luka

1.

Kelompok perlakuan basis gel

Diameter awal (Cm)

=

2.01

Diameter hari ke-1 (Cm)

= 1.99

× 100%

= 0.995%

2.

Kelompok perlakuan GETH1%

Diameter awal (Cm)

=

2.01

Diameter hari ke-1 (Cm)

= 2.00

× 100%

= 0.498%

3.

Kelompok perlakuan GETH 3%

Diameter awal (Cm)

=

2.00

Diameter hari ke-1 (Cm)

= 1.99

× 100%

= 0,5%

4.

Kelompok perlakuan GETH 5%

Diameter awal (Cm)

=

2.10

Diameter hari ke-1 (Cm)

= 2.01

× 100%

= 4,286%

5.

Kelompok perlakuan betadine salep

Diameter awal (Cm)

=

2.01

Diameter hari ke-1 (Cm)

= 2.00

× 100%


(21)

Lampiran 21. Hasil statistik persentase pengurangan diameter luka

Perlakuan

Kolmogorov-Smirnova Shapiro-Wilk

Statistic df Sig. Statistic df Sig.

H_1 Basis Gel Carbomer 940 .348 5 .047 .770 5 .046

F1( GETH 1%) .335 5 .069 .750 5 .030

F2 (GETH 3%) .426 5 .003 .653 5 .003

F3 (GETH 5%) .419 5 .004 .659 5 .003

Betadine Salep .367 5 .026 .684 5 .006

H_2 Basis Gel Carbomer 940 .203 5 .200* .925 5 .561

F1( GETH 1%) .228 5 .200* .879 5 .303

F2 (GETH 3%) .207 5 .200* .928 5 .580

F3 (GETH 5%) .268 5 .200* .855 5 .211

Betadine Salep .198 5 .200* .936 5 .636

H_3 Basis Gel Carbomer 940 .177 5 .200* .959 5 .803

F1( GETH 1%) .328 5 .083 .798 5 .079

F2 (GETH 3%) .325 5 .090 .824 5 .125

F3 (GETH 5%) .289 5 .200* .925 5 .564

Betadine Salep .272 5 .200* .939 5 .661

H_4 Basis Gel Carbomer 940 .280 5 .200* .820 5 .116

F1( GETH 1%) .165 5 .200* .962 5 .825

F2 (GETH 3%) .281 5 .200* .867 5 .256

F3 (GETH 5%) .323 5 .096 .892 5 .365

Betadine Salep .253 5 .200* .929 5 .588

H_5 Basis Gel Carbomer 940 .219 5 .200* .920 5 .530

F1( GETH 1%) .228 5 .200* .849 5 .190

F2 (GETH 3%) .292 5 .190 .871 5 .271

F3 (GETH 5%) .178 5 .200* .963 5 .831

Betadine Salep .259 5 .200* .938 5 .653

H_6 Basis Gel Carbomer 940 .213 5 .200* .930 5 .599

F1( GETH 1%) .300 5 .161 .901 5 .415

F2 (GETH 3%) .354 5 .040 .800 5 .080

F3 (GETH 5%) .208 5 .200* .910 5 .468

Betadine Salep .193 5 .200* .933 5 .619

H_7 Basis Gel Carbomer 940 .176 5 .200* .922 5 .542

F1( GETH 1%) .154 5 .200* .984 5 .954

F2 (GETH 3%) .187 5 .200* .976 5 .910

F3 (GETH 5%) .212 5 .200* .974 5 .902

Betadine Salep .247 5 .200* .950 5 .739

H_8 Basis Gel Carbomer 940 .161 5 .200* .981 5 .940

F1( GETH 1%) .193 5 .200* .948 5 .724

F2 (GETH 3%) .287 5 .200* .911 5 .475

F3 (GETH 5%) .118 5 .200* 1.000 5 1.000


(22)

Lampiran 21.

(Lanjutan)

H_9 Basis Gel Carbomer 940 .265 5 .200* .945 5 .701

F1( GETH 1%) .273 5 .200* .838 5 .159

F2 (GETH 3%) .213 5 .200* .938 5 .653

F3 (GETH 5%) .194 5 .200* .939 5 .661

Betadine Salep .224 5 .200* .903 5 .425

H_10 Basis Gel Carbomer 940 .200 5 .200* .949 5 .730

F1( GETH 1%) .318 5 .110 .806 5 .091

F2 (GETH 3%) .197 5 .200* .976 5 .911

F3 (GETH 5%) .314 5 .122 .859 5 .225

Betadine Salep .210 5 .200* .936 5 .637

H_11 Basis Gel Carbomer 940 .249 5 .200* .885 5 .332

F1( GETH 1%) .281 5 .200* .864 5 .245

F2 (GETH 3%) .214 5 .200* .924 5 .557

F3 (GETH 5%) .198 5 .200* .970 5 .877

Betadine Salep .230 5 .200* .956 5 .783

H_12 Basis Gel Carbomer 940 .191 5 .200* .962 5 .824

F1( GETH 1%) .216 5 .200* .904 5 .435

F2 (GETH 3%) .312 5 .126 .840 5 .164

F3 (GETH 5%) .208 5 .200* .921 5 .539

Betadine Salep .345 5 .051 .802 5 .085

H_13 Basis Gel Carbomer 940 .321 5 .101 .856 5 .214

F1( GETH 1%) .205 5 .200* .922 5 .546

F2 (GETH 3%) .277 5 .200* .868 5 .260

F3 (GETH 5%) .238 5 .200* .887 5 .345

Betadine Salep .309 5 .133 .820 5 .118

H_14 Basis Gel Carbomer 940 .226 5 .200* .883 5 .321

F1( GETH 1%) .359 5 .034 .842 5 .172

F2 (GETH 3%) .219 5 .200* .969 5 .867

F3 (GETH 5%) .233 5 .200* .934 5 .623

Betadine Salep .180 5 .200* .975 5 .906

H_15 Basis Gel Carbomer 940 .315 5 .117 .857 5 .217

F1( GETH 1%) .226 5 .200* .964 5 .833

F2 (GETH 3%) .321 5 .101 .893 5 .371

F3 (GETH 5%) .246 5 .200* .913 5 .486

Betadine Salep .304 5 .148 .786 5 .06

H_16 Basis Gel Carbomer 940 .203 5 .200* .951 5 .746

F1( GETH 1%) .242 5 .200* .932 5 .609

F2 (GETH 3%) .260 5 .200* .926 5 .571

F3 (GETH 5%) .154 5 .200* .977 5 .920


(23)

Lampiran 21.

(Lanjutan)

H_17 Basis Gel Carbomer 940 .208 5 .200* .907 5 .448

F1( GETH 1%) .224 5 .200* .903 5 .427

F2 (GETH 3%) .389 5 .013 .798 5 .077

F3 (GETH 5%) .243 5 .200* .878 5 .301

Betadine Salep .276 5 .200* .832 5 .143

H_18 Basis Gel Carbomer 940 .176 5 .200* .955 5 .776

F1( GETH 1%) .278 5 .200* .926 5 .572

F2 (GETH 3%) .241 5 .200* .959 5 .798

F3 (GETH 5%) .216 5 .200* .928 5 .582

Betadine Salep .224 5 .200* .865 5 .246

H_19 Basis Gel Carbomer 940 .205 5 .200* .920 5 .529

F1( GETH 1%) .255 5 .200* .851 5 .199

F2 (GETH 3%) .232 5 .200* .894 5 .375

F3 (GETH 5%) .223 5 .200* .895 5 .381

H_20 Basis Gel Carbomer 940 .261 5 .200* .934 5 .624

H_21 Basis Gel Carbomer 940 .247 5 .200* .883 5 .321


(24)

Lampiran 21.

(Lanjutan)

Ranks

Perlakuan N Mean Rank

H_1 Basis Gel Carbomer 940 5 8.90

F1( GETH 1%) 5 17.30

F2 (GETH 3%) 5 13.60

F3 (GETH 5%) 5 10.10

Betadine Salep 5 15.10

Total 25

Test Statisticsa,b

H_1

Chi-Square 4.703

df 4

Asymp. Sig. .319

a. Kruskal Wallis Test b. Grouping Variable: perlakuan

Mann-Whitney Test

Ranks

Perlakuan N Mean Rank Sum of Ranks

H_1 Basis Gel Carbomer 940 5 3.80 19.00

F1( GETH 1%) 5 7.20 36.00

Total 10

Test Statisticsb

H_1

Mann-Whitney U 4.000

Wilcoxon W 19.000

Z -1.820

Asymp. Sig. (2-tailed) .069

Exact Sig. [2*(1-tailed Sig.)] .095a

a. Not corrected for ties. b. Grouping Variable: perlakuan

Ranks

Perlakuan N Mean Rank Sum of Ranks

H_1 Basis Gel Carbomer 940 5 3.80 19.00

F1( GETH 1%) 5 7.20 36.00


(25)

Lampiran 21.

(Lanjutan)

Test Statisticsb

H_1

Mann-Whitney U 4.000

Wilcoxon W 19.000

Z -1.820

Asymp. Sig. (2-tailed) .069

Exact Sig. [2*(1-tailed Sig.)] .095a

a. Not corrected for ties. b. Grouping Variable: perlakuan

Ranks

Perlakuan N Mean Rank Sum of Ranks

H_1 Basis Gel Carbomer 940 5 4.80 24.00

F2 (GETH 3%) 5 6.20 31.00

Total 10

Test Statisticsb

H_1

Mann-Whitney U 9.000

Wilcoxon W 24.000

Z -.783

Asymp. Sig. (2-tailed) .434

Exact Sig. [2*(1-tailed Sig.)] .548a

a. Not corrected for ties. b. Grouping Variable: perlakuan

Ranks

Perlakuan N Mean Rank Sum of Ranks

H_1 Basis Gel Carbomer 940 5 5.10 25.50

F3 (GETH 5%) 5 5.90 29.50

Total 10

Test Statisticsb

H_1

Mann-Whitney U 10.500

Wilcoxon W 25.500

Z -.447

Asymp. Sig. (2-tailed) .655

Exact Sig. [2*(1-tailed Sig.)] .690a

a. Not corrected for ties. b. Grouping Variable: perlakuan


(26)

Lampiran 21.

(Lanjutan)

Ranks

Perlakuan N Mean Rank Sum of Ranks

H_1 Basis Gel Carbomer 940 5 4.20 21.00

Betadine Salep 5 6.80 34.00

Total 10

Test Statisticsb

H_1

Mann-Whitney U 6.000

Wilcoxon W 21.000

Z -1.410

Asymp. Sig. (2-tailed) .159

Exact Sig. [2*(1-tailed Sig.)] .222a

a. Not corrected for ties. b. Grouping Variable: perlakuan

Ranks

Perlakuan N Mean Rank Sum of Ranks

H_1 F1( GETH 1%) 5 6.00 30.00

F2 (GETH 3%) 5 5.00 25.00

Total 10

Test Statisticsb

H_1

Mann-Whitney U 10.000

Wilcoxon W 25.000

Z -.532

Asymp. Sig. (2-tailed) .595

Exact Sig. [2*(1-tailed Sig.)] .690a

a. Not corrected for ties. b. Grouping Variable: perlakuan

Ranks

Perlakuan N Mean Rank Sum of Ranks

H_1 F1( GETH 1%) 5 7.00 35.00

F3 (GETH 5%) 5 4.00 20.00


(27)

Lampiran 21.

(Lanjutan)

Test Statisticsb

H_1

Mann-Whitney U 5.000

Wilcoxon W 20.000

Z -1.591

Asymp. Sig. (2-tailed) .112

Exact Sig. [2*(1-tailed Sig.)] .151a

a. Not corrected for ties. b. Grouping Variable: perlakuan

Ranks

Perlakuan N Mean Rank Sum of Ranks

H_1 F1( GETH 1%) 5 6.10 30.50

Betadine Salep 5 4.90 24.50

Total 10

Test Statisticsb

H_1

Mann-Whitney U 9.500

Wilcoxon W 24.500

Z -.669

Asymp. Sig. (2-tailed) .504

Exact Sig. [2*(1-tailed Sig.)] .548a

a. Not corrected for ties. b. Grouping Variable: perlakuan

Ranks

Perlakuan N Mean Rank Sum of Ranks

H_1 F2 (GETH 3%) 5 6.00 30.00

F3 (GETH 5%) 5 5.00 25.00

Total 10

Test Statisticsb

H_1

Mann-Whitney U 10.000

Wilcoxon W 25.000

Z -.541

Asymp. Sig. (2-tailed) .589

Exact Sig. [2*(1-tailed Sig.)] .690a

a. Not corrected for ties.


(28)

Lampiran 21.

(Lanjutan)

Ranks

Perlakuan N Mean Rank Sum of Ranks

H_1 F2 (GETH 3%) 5 5.40 27.00

Betadine Salep 5 5.60 28.00

Total 10

Test Statisticsb

H_1

Mann-Whitney U 12.000

Wilcoxon W 27.000

Z -.112

Asymp. Sig. (2-tailed) .911

Exact Sig. [2*(1-tailed Sig.)] 1.000a

a. Not corrected for ties. b. Grouping Variable: perlakuan


(29)

Lampiran 21.

(Lanjutan)

Sum of Squares Df Mean Square F Sig.

H_2 Between Groups 42.767 4 10.692 1.645 .202

Within Groups 130.013 20 6.501

Total 172.781 24

H_3 Between Groups 58.347 4 14.587 1.121 .374

Within Groups 260.202 20 13.010

Total 318.549 24

H_4 Between Groups 28.272 4 7.068 .291 .881

Within Groups 486.515 20 24.326

Total 514.788 24

H_5 Between Groups 25.138 4 6.285 .104 .980

Within Groups 1211.422 20 60.571

Total 1236.560 24

H_6 Between Groups 146.937 4 36.734 .442 .777

Within Groups 1661.113 20 83.056

Total 1808.049 24

H_7 Between Groups 256.852 4 64.213 .872 .498

Within Groups 1472.941 20 73.647

Total 1729.793 24

H_8 Between Groups 620.697 4 155.174 1.972 .138

Within Groups 1574.017 20 78.701

Total 2194.714 24

H_9 Between Groups 612.579 4 153.145 1.512 .237

Within Groups 2025.602 20 101.280

Total 2638.181 24

H_10 Between Groups 443.115 4 110.779 2.241 .101

Within Groups 988.790 20 49.439

Total 1431.905 24

H_11 Between Groups 297.250 4 74.312 1.890 .152

Within Groups 786.367 20 39.318

Total 1083.617 24

H_12 Between Groups 357.714 4 89.428 3.563 .024

Within Groups 501.991 20 25.100

Total 859.704 24

H_13 Between Groups 353.509 4 88.377 3.527 .025

Within Groups 501.128 20 25.056

Total 854.637 24

H_14 Between Groups 432.926 4 108.232 5.720 .003

Within Groups 378.419 20 18.921


(30)

Lampiran 21.

(Lanjutan)

H_15 Between Groups 484.556 4 121.139 8.163 .000

Within Groups 296.805 20 14.840

Total 781.361 24

H_16 Between Groups 264.716 4 66.179 5.361 .004

Within Groups 246.882 20 12.344

Total 511.598 24

H_17 Between Groups 355.604 4 88.901 11.409 .000

Within Groups 155.850 20 7.792

Total 511.454 24

H_18 Between Groups 264.652 4 66.163 13.618 .000

Within Groups 97.170 20 4.859

Total 361.822 24

H_19 Between Groups 160.626 4 40.157 12.639 .000

Within Groups 63.543 20 3.177

Total 224.169 24

H_20 Between Groups 112.106 4 28.026 32.329 .000

Within Groups 17.338 20 .867

Total 129.444 24

H_21 Between Groups 29.160 4 7.290 5.245 .005

Within Groups 27.800 20 1.390

Total 56.960 24

H_22 Between Groups 11.560 4 2.890 3.440 .027

Within Groups 16.800 20 .840

Total 28.360 24

H_23 Between Groups .000 4 .000 . .

Within Groups .000 20 .000


(31)

Lampiran 21.

(Lanjutan)

Multiple Comparisons

Depende nt

Variable (I) perlakuan (J) perlakuan

Mean Difference

(I-J)

Std. Error Sig.

95% Confidence Interval Lower Bound

Upper Bound

H_2 Basis Gel Carbomer 940 F1( GETH 1%) .40400 1.61253 .999 -4.4213 5.2293

F2 (GETH 3%) -1.82200 1.61253 .789 -6.6473 3.0033

F3 (GETH 5%) -2.37400 1.61253 .591 -7.1993 2.4513

Betadine Salep

.99800 1.61253 .970 -3.8273 5.8233

F1( GETH 1%) Basis Gel

Carbomer 940

-.40400 1.61253 .999 -5.2293 4.4213

F2 (GETH 3%) -2.22600 1.61253 .646 -7.0513 2.5993

F3 (GETH 5%) -2.77800 1.61253 .443 -7.6033 2.0473

Betadine Salep

.59400 1.61253 .996 -4.2313 5.4193

F2 (GETH 3%) Basis Gel

Carbomer 940

1.82200 1.61253 .789 -3.0033 6.6473

F1( GETH 1%) 2.22600 1.61253 .646 -2.5993 7.0513

F3 (GETH 5%) -.55200 1.61253 .997 -5.3773 4.2733

Betadine Salep

2.82000 1.61253 .429 -2.0053 7.6453

F3 (GETH 5%) Basis Gel

Carbomer 940

2.37400 1.61253 .591 -2.4513 7.1993

F1( GETH 1%) 2.77800 1.61253 .443 -2.0473 7.6033

F2 (GETH 3%) .55200 1.61253 .997 -4.2733 5.3773

Betadine Salep


(32)

Lampiran 21. (Lanjutan)

Betadine Salep Basis Gel

Carbomer 940

-.99800 1.61253 .970 -5.8233 3.8273

F1( GETH 1%) -.59400 1.61253 .996 -5.4193 4.2313

F2 (GETH 3%) -2.82000 1.61253 .429 -7.6453 2.0053

F3 (GETH 5%) -3.37200 1.61253 .262 -8.1973 1.4533

H_3 Basis Gel Carbomer 940 F1( GETH 1%) 2.51400 2.28123 .803 -4.3123 9.3403

F2 (GETH 3%) -1.58600 2.28123 .955 -8.4123 5.2403

F3 (GETH 5%) -1.16800 2.28123 .985 -7.9943 5.6583

Betadine Salep

1.30200 2.28123 .978 -5.5243 8.1283

F1( GETH 1%) Basis Gel

Carbomer 940

-2.51400 2.28123 .803 -9.3403 4.3123

F2 (GETH 3%) -4.10000 2.28123 .402

-10.9263

2.7263

F3 (GETH 5%) -3.68200 2.28123 .506

-10.5083

3.1443

Betadine Salep

-1.21200 2.28123 .983 -8.0383 5.6143

F2 (GETH 3%) Basis Gel

Carbomer 940

1.58600 2.28123 .955 -5.2403 8.4123

F1( GETH 1%) 4.10000 2.28123 .402 -2.7263 10.9263

F3 (GETH 5%) .41800 2.28123 1.000 -6.4083 7.2443

Betadine Salep

2.88800 2.28123 .714 -3.9383 9.7143

F3 (GETH 5%) Basis Gel

Carbomer 940

1.16800 2.28123 .985 -5.6583 7.9943

F1( GETH 1%) 3.68200 2.28123 .506 -3.1443 10.5083

F2 (GETH 3%) -.41800 2.28123 1.000 -7.2443 6.4083

Betadine Salep


(33)

Lampiran 21. (Lanjutan)

Betadine Salep Basis Gel

Carbomer 940

-1.30200 2.28123 .978 -8.1283 5.5243

F1( GETH 1%) 1.21200 2.28123 .983 -5.6143 8.0383

F2 (GETH 3%) -2.88800 2.28123 .714 -9.7143 3.9383

F3 (GETH 5%) -2.47000 2.28123 .813 -9.2963 4.3563

H_4 Basis Gel Carbomer 940 F1( GETH 1%) 2.77600 3.11934 .897 -6.5582 12.1102

F2 (GETH 3%) 1.55600 3.11934 .987 -7.7782 10.8902

F3 (GETH 5%) -.03200 3.11934 1.000 -9.3662 9.3022

Betadine Salep

.64400 3.11934 1.000 -8.6902 9.9782

F1( GETH 1%) Basis Gel

Carbomer 940

-2.77600 3.11934 .897

-12.1102

6.5582

F2 (GETH 3%) -1.22000 3.11934 .995

-10.5542

8.1142

F3 (GETH 5%) -2.80800 3.11934 .893

-12.1422

6.5262

Betadine Salep

-2.13200 3.11934 .958

-11.4662

7.2022

F2 (GETH 3%) Basis Gel

Carbomer 940

-1.55600 3.11934 .987

-10.8902

7.7782

F1( GETH 1%) 1.22000 3.11934 .995 -8.1142 10.5542

F3 (GETH 5%) -1.58800 3.11934 .985

-10.9222

7.7462

Betadine Salep

-.91200 3.11934 .998

-10.2462

8.4222

F3 (GETH 5%) Basis Gel

Carbomer 940

.03200 3.11934 1.000 -9.3022 9.3662

F1( GETH 1%) 2.80800 3.11934 .893 -6.5262 12.1422

F2 (GETH 3%) 1.58800 3.11934 .985 -7.7462 10.9222

Betadine Salep


(34)

Lampiran 21. (Lanjutan)

Betadine Salep Basis Gel

Carbomer 940

-.64400 3.11934 1.000 -9.9782 8.6902

F1( GETH 1%) 2.13200 3.11934 .958 -7.2022 11.4662

F2 (GETH 3%) .91200 3.11934 .998 -8.4222 10.2462

F3 (GETH 5%) -.67600 3.11934 .999

-10.0102

8.6582

H_5 Basis Gel Carbomer 940 F1( GETH 1%) -2.46200 4.92224 .986

-17.1912

12.2672

F2 (GETH 3%) -.87000 4.92224 1.000

-15.5992

13.8592

F3 (GETH 5%) -1.95200 4.92224 .994

-16.6812

12.7772

Betadine Salep

-.00800 4.92224 1.000

-14.7372

14.7212

F1( GETH 1%) Basis Gel

Carbomer 940

2.46200 4.92224 .986

-12.2672

17.1912

F2 (GETH 3%) 1.59200 4.92224 .997

-13.1372

16.3212

F3 (GETH 5%) .51000 4.92224 1.000

-14.2192

15.2392

Betadine Salep

2.45400 4.92224 .987

-12.2752

17.1832

F2 (GETH 3%) Basis Gel

Carbomer 940

.87000 4.92224 1.000

-13.8592

15.5992

F1( GETH 1%) -1.59200 4.92224 .997

-16.3212

13.1372

F3 (GETH 5%) -1.08200 4.92224 .999

-15.8112

13.6472

Betadine Salep

.86200 4.92224 1.000

-13.8672


(35)

Lampiran 21. (Lanjutan)

F3 (GETH 5%) Basis Gel

Carbomer 940

1.95200 4.92224 .994

-12.7772

16.6812

F1( GETH 1%) -.51000 4.92224 1.000

-15.2392

14.2192

F2 (GETH 3%) 1.08200 4.92224 .999

-13.6472

15.8112

Betadine Salep

1.94400 4.92224 .994

-12.7852

16.6732

Betadine Salep Basis Gel

Carbomer 940

.00800 4.92224 1.000

-14.7212

14.7372

F1( GETH 1%) -2.45400 4.92224 .987

-17.1832

12.2752

F2 (GETH 3%) -.86200 4.92224 1.000

-15.5912

13.8672

F3 (GETH 5%) -1.94400 4.92224 .994

-16.6732

12.7852

H_6 Basis Gel Carbomer 940 F1( GETH 1%) -5.45200 5.76387 .875

-22.6997

11.7957

F2 (GETH 3%) -5.33800 5.76387 .883

-22.5857

11.9097

F3 (GETH 5%) -6.08600 5.76387 .826

-23.3337

11.1617

Betadine Salep

-1.63800 5.76387 .998

-18.8857

15.6097

F1( GETH 1%) Basis Gel

Carbomer 940

5.45200 5.76387 .875

-11.7957

22.6997

F2 (GETH 3%) .11400 5.76387 1.000

-17.1337

17.3617

F3 (GETH 5%) -.63400 5.76387 1.000

-17.8817

16.6137

Betadine Salep

3.81400 5.76387 .962

-13.4337


(36)

Lampiran 21. (Lanjutan)

F2 (GETH 3%) Basis Gel

Carbomer 940

5.33800 5.76387 .883

-11.9097

22.5857

F1( GETH 1%) -.11400 5.76387 1.000

-17.3617

17.1337

F3 (GETH 5%) -.74800 5.76387 1.000

-17.9957

16.4997

Betadine Salep

3.70000 5.76387 .966

-13.5477

20.9477

F3 (GETH 5%) Basis Gel

Carbomer 940

6.08600 5.76387 .826

-11.1617

23.3337

F1( GETH 1%) .63400 5.76387 1.000

-16.6137

17.8817

F2 (GETH 3%) .74800 5.76387 1.000

-16.4997

17.9957

Betadine Salep

4.44800 5.76387 .936

-12.7997

21.6957

Betadine Salep Basis Gel

Carbomer 940

1.63800 5.76387 .998

-15.6097

18.8857

F1( GETH 1%) -3.81400 5.76387 .962

-21.0617

13.4337

F2 (GETH 3%) -3.70000 5.76387 .966

-20.9477

13.5477

F3 (GETH 5%) -4.44800 5.76387 .936

-21.6957

12.7997

H_7 Basis Gel Carbomer 940 F1( GETH 1%) -5.92600 5.42760 .809

-22.1674

10.3154

F2 (GETH 3%) -8.61200 5.42760 .522

-24.8534

7.6294

F3 (GETH 5%) -7.59600 5.42760 .635

-23.8374

8.6454

Betadine Salep

-2.60400 5.42760 .988

-18.8454


(37)

Lampiran 21. (Lanjutan)

F1( GETH 1%) Basis Gel

Carbomer 940

5.92600 5.42760 .809

-10.3154

22.1674

F2 (GETH 3%) -2.68600 5.42760 .987

-18.9274

13.5554

F3 (GETH 5%) -1.67000 5.42760 .998

-17.9114

14.5714

Betadine Salep

3.32200 5.42760 .971

-12.9194

19.5634

F2 (GETH 3%) Basis Gel

Carbomer 940

8.61200 5.42760 .522 -7.6294 24.8534

F1( GETH 1%) 2.68600 5.42760 .987

-13.5554

18.9274

F3 (GETH 5%) 1.01600 5.42760 1.000

-15.2254

17.2574

Betadine Salep

6.00800 5.42760 .801

-10.2334

22.2494

F3 (GETH 5%) Basis Gel

Carbomer 940

7.59600 5.42760 .635 -8.6454 23.8374

F1( GETH 1%) 1.67000 5.42760 .998

-14.5714

17.9114

F2 (GETH 3%) -1.01600 5.42760 1.000

-17.2574

15.2254

Betadine Salep

4.99200 5.42760 .886

-11.2494

21.2334

Betadine Salep Basis Gel

Carbomer 940

2.60400 5.42760 .988

-13.6374

18.8454

F1( GETH 1%) -3.32200 5.42760 .971

-19.5634

12.9194

F2 (GETH 3%) -6.00800 5.42760 .801

-22.2494

10.2334

F3 (GETH 5%) -4.99200 5.42760 .886

-21.2334


(38)

Lampiran 21. (Lanjutan)

H_8 Basis Gel Carbomer 940 F1( GETH 1%) .36800 5.61073 1.000

-16.4214

17.1574

F2 (GETH 3%) -6.25800 5.61073 .797

-23.0474

10.5314

F3 (GETH 5%) -13.27000 5.61073 .166

-30.0594

3.5194

Betadine Salep

-5.60000 5.61073 .853

-22.3894

11.1894

F1( GETH 1%) Basis Gel

Carbomer 940

-.36800 5.61073 1.000

-17.1574

16.4214

F2 (GETH 3%) -6.62600 5.61073 .762

-23.4154

10.1634

F3 (GETH 5%) -13.63800 5.61073 .148

-30.4274

3.1514

Betadine Salep

-5.96800 5.61073 .823

-22.7574

10.8214

F2 (GETH 3%) Basis Gel

Carbomer 940

6.25800 5.61073 .797

-10.5314

23.0474

F1( GETH 1%) 6.62600 5.61073 .762

-10.1634

23.4154

F3 (GETH 5%) -7.01200 5.61073 .723

-23.8014

9.7774

Betadine Salep

.65800 5.61073 1.000

-16.1314

17.4474

F3 (GETH 5%) Basis Gel

Carbomer 940

13.27000 5.61073 .166 -3.5194 30.0594

F1( GETH 1%) 13.63800 5.61073 .148 -3.1514 30.4274

F2 (GETH 3%) 7.01200 5.61073 .723 -9.7774 23.8014

Betadine Salep


(39)

Lampiran 21. (Lanjutan)

Betadine Salep Basis Gel

Carbomer 940

5.60000 5.61073 .853

-11.1894

22.3894

F1( GETH 1%) 5.96800 5.61073 .823

-10.8214

22.7574

F2 (GETH 3%) -.65800 5.61073 1.000

-17.4474

16.1314

F3 (GETH 5%) -7.67000 5.61073 .654

-24.4594

9.1194

H_9 Basis Gel Carbomer 940 F1( GETH 1%) -2.77000 6.36491 .992

-21.8162

16.2762

F2 (GETH 3%) -8.12600 6.36491 .708

-27.1722

10.9202

F3 (GETH 5%) -13.47600 6.36491 .252

-32.5222

5.5702

Betadine Salep

-10.52400 6.36491 .483

-29.5702

8.5222

F1( GETH 1%) Basis Gel

Carbomer 940

2.77000 6.36491 .992

-16.2762

21.8162

F2 (GETH 3%) -5.35600 6.36491 .914

-24.4022

13.6902

F3 (GETH 5%) -10.70600 6.36491 .466

-29.7522

8.3402

Betadine Salep

-7.75400 6.36491 .741

-26.8002

11.2922

F2 (GETH 3%) Basis Gel

Carbomer 940

8.12600 6.36491 .708

-10.9202

27.1722

F1( GETH 1%) 5.35600 6.36491 .914

-13.6902

24.4022

F3 (GETH 5%) -5.35000 6.36491 .915

-24.3962

13.6962

Betadine Salep

-2.39800 6.36491 .995

-21.4442


(40)

Lampiran 21. (Lanjutan)

F3 (GETH 5%) Basis Gel

Carbomer 940

13.47600 6.36491 .252 -5.5702 32.5222

F1( GETH 1%) 10.70600 6.36491 .466 -8.3402 29.7522

F2 (GETH 3%) 5.35000 6.36491 .915

-13.6962

24.3962

Betadine Salep

2.95200 6.36491 .990

-16.0942

21.9982

Betadine Salep Basis Gel

Carbomer 940

10.52400 6.36491 .483 -8.5222 29.5702

F1( GETH 1%) 7.75400 6.36491 .741

-11.2922

26.8002

F2 (GETH 3%) 2.39800 6.36491 .995

-16.6482

21.4442

F3 (GETH 5%) -2.95200 6.36491 .990

-21.9982

16.0942

H_10 Basis Gel Carbomer 940 F1( GETH 1%) -.36400 4.44700 1.000

-13.6711

12.9431

F2 (GETH 3%) -3.69200 4.44700 .918

-16.9991

9.6151

F3 (GETH 5%) -11.70200 4.44700 .102

-25.0091

1.6051

Betadine Salep

-3.98200 4.44700 .895

-17.2891

9.3251

F1( GETH 1%) Basis Gel

Carbomer 940

.36400 4.44700 1.000

-12.9431

13.6711

F2 (GETH 3%) -3.32800 4.44700 .942

-16.6351

9.9791

F3 (GETH 5%) -11.33800 4.44700 .119

-24.6451

1.9691

Betadine Salep

-3.61800 4.44700 .923

-16.9251


(41)

Lampiran 21. (Lanjutan)

F2 (GETH 3%) Basis Gel

Carbomer 940

3.69200 4.44700 .918 -9.6151 16.9991

F1( GETH 1%) 3.32800 4.44700 .942 -9.9791 16.6351

F3 (GETH 5%) -8.01000 4.44700 .400

-21.3171

5.2971

Betadine Salep

-.29000 4.44700 1.000

-13.5971

13.0171

F3 (GETH 5%) Basis Gel

Carbomer 940

11.70200 4.44700 .102 -1.6051 25.0091

F1( GETH 1%) 11.33800 4.44700 .119 -1.9691 24.6451

F2 (GETH 3%) 8.01000 4.44700 .400 -5.2971 21.3171

Betadine Salep

7.72000 4.44700 .436 -5.5871 21.0271

Betadine Salep Basis Gel

Carbomer 940

3.98200 4.44700 .895 -9.3251 17.2891

F1( GETH 1%) 3.61800 4.44700 .923 -9.6891 16.9251

F2 (GETH 3%) .29000 4.44700 1.000

-13.0171

13.5971

F3 (GETH 5%) -7.72000 4.44700 .436

-21.0271

5.5871

H_11 Basis Gel Carbomer 940 F1( GETH 1%) -1.96400 3.96577 .987

-13.8311

9.9031

F2 (GETH 3%) -6.46000 3.96577 .497

-18.3271

5.4071

F3 (GETH 5%) -9.22800 3.96577 .178

-21.0951

2.6391

Betadine Salep

-7.28600 3.96577 .381

-19.1531

4.5811

F1( GETH 1%) Basis Gel

Carbomer 940

1.96400 3.96577 .987 -9.9031 13.8311

F2 (GETH 3%) -4.49600 3.96577 .787

-16.3631

7.3711

F3 (GETH 5%) -7.26400 3.96577 .384

-19.1311


(42)

Lampiran 21. (Lanjutan)

Betadine Salep

-5.32200 3.96577 .669

-17.1891

6.5451

F2 (GETH 3%) Basis Gel

Carbomer 940

6.46000 3.96577 .497 -5.4071 18.3271

F1( GETH 1%) 4.49600 3.96577 .787 -7.3711 16.3631

F3 (GETH 5%) -2.76800 3.96577 .955

-14.6351

9.0991

Betadine Salep

-.82600 3.96577 1.000

-12.6931

11.0411

F3 (GETH 5%) Basis Gel

Carbomer 940

9.22800 3.96577 .178 -2.6391 21.0951

F1( GETH 1%) 7.26400 3.96577 .384 -4.6031 19.1311

F2 (GETH 3%) 2.76800 3.96577 .955 -9.0991 14.6351

Betadine Salep

1.94200 3.96577 .987 -9.9251 13.8091

Betadine Salep Basis Gel

Carbomer 940

7.28600 3.96577 .381 -4.5811 19.1531

F1( GETH 1%) 5.32200 3.96577 .669 -6.5451 17.1891

F2 (GETH 3%) .82600 3.96577 1.000

-11.0411

12.6931

F3 (GETH 5%) -1.94200 3.96577 .987

-13.8091

9.9251

H_12 Basis Gel Carbomer 940 F1( GETH 1%) -3.14800 3.16857 .855

-12.6295

6.3335

F2 (GETH 3%) -3.95200 3.16857 .725

-13.4335

5.5295

F3 (GETH 5%)

-10.81400*

3.16857 .021

-20.2955

-1.3325

Betadine Salep

-7.88800 3.16857 .133

-17.3695

1.5935

F1( GETH 1%) Basis Gel

Carbomer 940

3.14800 3.16857 .855 -6.3335 12.6295

F2 (GETH 3%) -.80400 3.16857 .999

-10.2855


(43)

Lampiran 21. (Lanjutan)

F3 (GETH 5%) -7.66600 3.16857 .151

-17.1475

1.8155

Betadine Salep

-4.74000 3.16857 .577

-14.2215

4.7415

F2 (GETH 3%) Basis Gel

Carbomer 940

3.95200 3.16857 .725 -5.5295 13.4335

F1( GETH 1%) .80400 3.16857 .999 -8.6775 10.2855

F3 (GETH 5%) -6.86200 3.16857 .233

-16.3435

2.6195

Betadine Salep

-3.93600 3.16857 .728

-13.4175

5.5455

F3 (GETH 5%) Basis Gel

Carbomer 940

10.81400* 3.16857 .021 1.3325 20.2955

F1( GETH 1%) 7.66600 3.16857 .151 -1.8155 17.1475

F2 (GETH 3%) 6.86200 3.16857 .233 -2.6195 16.3435

Betadine Salep

2.92600 3.16857 .884 -6.5555 12.4075

Betadine Salep Basis Gel

Carbomer 940

7.88800 3.16857 .133 -1.5935 17.3695

F1( GETH 1%) 4.74000 3.16857 .577 -4.7415 14.2215

F2 (GETH 3%) 3.93600 3.16857 .728 -5.5455 13.4175

F3 (GETH 5%) -2.92600 3.16857 .884

-12.4075

6.5555

H_13 Basis Gel Carbomer 940 F1( GETH 1%) -3.73400 3.16584 .763

-13.2074

5.7394

F2 (GETH 3%) -3.92600 3.16584 .729

-13.3994

5.5474

F3 (GETH 5%)

-10.92000*

3.16584 .019

-20.3934

-1.4466

Betadine Salep

-7.88600 3.16584 .133

-17.3594

1.5874

F1( GETH 1%) Basis Gel

Carbomer 940

3.73400 3.16584 .763 -5.7394 13.2074


(44)

Lampiran 21. (Lanjutan)

F3 (GETH 5%) -7.18600 3.16584 .196

-16.6594

2.2874

Betadine Salep

-4.15200 3.16584 .687

-13.6254

5.3214

F2 (GETH 3%) Basis Gel

Carbomer 940

3.92600 3.16584 .729 -5.5474 13.3994

F1( GETH 1%) .19200 3.16584 1.000 -9.2814 9.6654

F3 (GETH 5%) -6.99400 3.16584 .217

-16.4674

2.4794

Betadine Salep

-3.96000 3.16584 .723

-13.4334

5.5134

F3 (GETH 5%) Basis Gel

Carbomer 940

10.92000* 3.16584 .019 1.4466 20.3934

F1( GETH 1%) 7.18600 3.16584 .196 -2.2874 16.6594

F2 (GETH 3%) 6.99400 3.16584 .217 -2.4794 16.4674

Betadine Salep

3.03400 3.16584 .870 -6.4394 12.5074

Betadine Salep Basis Gel

Carbomer 940

7.88600 3.16584 .133 -1.5874 17.3594

F1( GETH 1%) 4.15200 3.16584 .687 -5.3214 13.6254

F2 (GETH 3%) 3.96000 3.16584 .723 -5.5134 13.4334

F3 (GETH 5%) -3.03400 3.16584 .870

-12.5074

6.4394

H_14 Basis Gel Carbomer 940 F1( GETH 1%) -6.22600 2.75107 .198

-14.4582

2.0062

F2 (GETH 3%) -8.07000 2.75107 .056

-16.3022

.1622

F3 (GETH 5%)

-11.36800*

2.75107 .004

-19.6002 -3.1358 Betadine Salep -11.17600*

2.75107 .005

-19.4082

-2.9438

F1( GETH 1%) Basis Gel

Carbomer 940


(45)

Lampiran 21. (Lanjutan)

F2 (GETH 3%) -1.84400 2.75107 .961

-10.0762

6.3882

F3 (GETH 5%) -5.14200 2.75107 .365

-13.3742

3.0902

Betadine Salep

-4.95000 2.75107 .401

-13.1822

3.2822

F2 (GETH 3%) Basis Gel

Carbomer 940

8.07000 2.75107 .056 -.1622 16.3022

F1( GETH 1%) 1.84400 2.75107 .961 -6.3882 10.0762

F3 (GETH 5%) -3.29800 2.75107 .752

-11.5302

4.9342

Betadine Salep

-3.10600 2.75107 .790

-11.3382

5.1262

F3 (GETH 5%) Basis Gel

Carbomer 940

11.36800* 2.75107 .004 3.1358 19.6002

F1( GETH 1%) 5.14200 2.75107 .365 -3.0902 13.3742

F2 (GETH 3%) 3.29800 2.75107 .752 -4.9342 11.5302

Betadine Salep

.19200 2.75107 1.000 -8.0402 8.4242

Betadine Salep Basis Gel

Carbomer 940

11.17600* 2.75107 .005 2.9438 19.4082

F1( GETH 1%) 4.95000 2.75107 .401 -3.2822 13.1822

F2 (GETH 3%) 3.10600 2.75107 .790 -5.1262 11.3382

F3 (GETH 5%) -.19200 2.75107 1.000 -8.4242 8.0402

H_15 Basis Gel Carbomer 940 F1( GETH 1%) -6.32400 2.43641 .109

-13.6147

.9667

F2 (GETH 3%) -6.76600 2.43641 .077

-14.0567

.5247

F3 (GETH 5%)

-10.98800*

2.43641 .002

-18.2787 -3.6973 Betadine Salep -12.66600*

2.43641 .000

-19.9567

-5.3753

F1( GETH 1%) Basis Gel

Carbomer 940


(46)

Lampiran 21. (Lanjutan)

F2 (GETH 3%) -.44200 2.43641 1.000 -7.7327 6.8487

F3 (GETH 5%) -4.66400 2.43641 .342

-11.9547

2.6267

Betadine Salep

-6.34200 2.43641 .108

-13.6327

.9487

F2 (GETH 3%) Basis Gel

Carbomer 940

6.76600 2.43641 .077 -.5247 14.0567

F1( GETH 1%) .44200 2.43641 1.000 -6.8487 7.7327

F3 (GETH 5%) -4.22200 2.43641 .438

-11.5127

3.0687

Betadine Salep

-5.90000 2.43641 .150

-13.1907

1.3907

F3 (GETH 5%) Basis Gel

Carbomer 940

10.98800* 2.43641 .002 3.6973 18.2787

F1( GETH 1%) 4.66400 2.43641 .342 -2.6267 11.9547

F2 (GETH 3%) 4.22200 2.43641 .438 -3.0687 11.5127

Betadine Salep

-1.67800 2.43641 .957 -8.9687 5.6127

Betadine Salep Basis Gel

Carbomer 940

12.66600* 2.43641 .000 5.3753 19.9567

F1( GETH 1%) 6.34200 2.43641 .108 -.9487 13.6327

F2 (GETH 3%) 5.90000 2.43641 .150 -1.3907 13.1907

F3 (GETH 5%) 1.67800 2.43641 .957 -5.6127 8.9687

H_16 Basis Gel Carbomer 940 F1( GETH 1%) -3.41400 2.22208 .552

-10.0633

3.2353

F2 (GETH 3%) -5.42600 2.22208 .145

-12.0753

1.2233

F3 (GETH 5%) -8.74800* 2.22208 .006

-15.3973

-2.0987

Betadine Salep

-8.37400* 2.22208 .009

-15.0233


(47)

Lampiran 21. (Lanjutan)

F1( GETH 1%) Basis Gel

Carbomer 940

3.41400 2.22208 .552 -3.2353 10.0633

F2 (GETH 3%) -2.01200 2.22208 .891 -8.6613 4.6373

F3 (GETH 5%) -5.33400 2.22208 .156

-11.9833

1.3153

Betadine Salep

-4.96000 2.22208 .209

-11.6093

1.6893

F2 (GETH 3%) Basis Gel

Carbomer 940

5.42600 2.22208 .145 -1.2233 12.0753

F1( GETH 1%) 2.01200 2.22208 .891 -4.6373 8.6613

F3 (GETH 5%) -3.32200 2.22208 .577 -9.9713 3.3273

Betadine Salep

-2.94800 2.22208 .679 -9.5973 3.7013

F3 (GETH 5%) Basis Gel

Carbomer 940

8.74800* 2.22208 .006 2.0987 15.3973

F1( GETH 1%) 5.33400 2.22208 .156 -1.3153 11.9833

F2 (GETH 3%) 3.32200 2.22208 .577 -3.3273 9.9713

Betadine Salep

.37400 2.22208 1.000 -6.2753 7.0233

Betadine Salep Basis Gel

Carbomer 940

8.37400* 2.22208 .009 1.7247 15.0233

F1( GETH 1%) 4.96000 2.22208 .209 -1.6893 11.6093

F2 (GETH 3%) 2.94800 2.22208 .679 -3.7013 9.5973

F3 (GETH 5%) -.37400 2.22208 1.000 -7.0233 6.2753

H_17 Basis Gel Carbomer 940 F1( GETH 1%) -4.51000 1.76550 .118 -9.7930 .7730

F2 (GETH 3%) -4.88000 1.76550 .079

-10.1630

.4030

F3 (GETH 5%) -8.04600* 1.76550 .002

-13.3290 -2.7630 Betadine Salep -11.27200*

1.76550 .000

-16.5550

-5.9890

F1( GETH 1%) Basis Gel

Carbomer 940


(48)

Lampiran 21. (Lanjutan)

F2 (GETH 3%) -.37000 1.76550 1.000 -5.6530 4.9130

F3 (GETH 5%) -3.53600 1.76550 .300 -8.8190 1.7470

Betadine Salep

-6.76200* 1.76550 .008

-12.0450

-1.4790

F2 (GETH 3%) Basis Gel

Carbomer 940

4.88000 1.76550 .079 -.4030 10.1630

F1( GETH 1%) .37000 1.76550 1.000 -4.9130 5.6530

F3 (GETH 5%) -3.16600 1.76550 .404 -8.4490 2.1170

Betadine Salep

-6.39200* 1.76550 .013

-11.6750

-1.1090

F3 (GETH 5%) Basis Gel

Carbomer 940

8.04600* 1.76550 .002 2.7630 13.3290

F1( GETH 1%) 3.53600 1.76550 .300 -1.7470 8.8190

F2 (GETH 3%) 3.16600 1.76550 .404 -2.1170 8.4490

Betadine Salep

-3.22600 1.76550 .386 -8.5090 2.0570

Betadine Salep Basis Gel

Carbomer 940

11.27200* 1.76550 .000 5.9890 16.5550

F1( GETH 1%) 6.76200* 1.76550 .008 1.4790 12.0450 F2 (GETH 3%) 6.39200* 1.76550 .013 1.1090 11.6750

F3 (GETH 5%) 3.22600 1.76550 .386 -2.0570 8.5090

H_18 Basis Gel Carbomer 940 F1( GETH 1%) -5.89600* 1.39406 .003

-10.0676

-1.7244

F2 (GETH 3%) -6.24600* 1.39406 .002

-10.4176

-2.0744

F3 (GETH 5%) -7.61200* 1.39406 .000

-11.7836


(49)

Lampiran 21. (Lanjutan)

Betadine Salep

-9.78200* 1.39406 .000

-13.9536

-5.6104

F1( GETH 1%) Basis Gel

Carbomer 940

5.89600* 1.39406 .003 1.7244 10.0676

F2 (GETH 3%) -.35000 1.39406 .999 -4.5216 3.8216

F3 (GETH 5%) -1.71600 1.39406 .734 -5.8876 2.4556

Betadine Salep

-3.88600 1.39406 .075 -8.0576 .2856

F2 (GETH 3%) Basis Gel

Carbomer 940

6.24600* 1.39406 .002 2.0744 10.4176

F1( GETH 1%) .35000 1.39406 .999 -3.8216 4.5216

F3 (GETH 5%) -1.36600 1.39406 .861 -5.5376 2.8056

Betadine Salep

-3.53600 1.39406 .122 -7.7076 .6356

F3 (GETH 5%) Basis Gel

Carbomer 940

7.61200* 1.39406 .000 3.4404 11.7836

F1( GETH 1%) 1.71600 1.39406 .734 -2.4556 5.8876

F2 (GETH 3%) 1.36600 1.39406 .861 -2.8056 5.5376

Betadine Salep

-2.17000 1.39406 .540 -6.3416 2.0016

Betadine Salep Basis Gel

Carbomer 940

9.78200* 1.39406 .000 5.6104 13.9536

F1( GETH 1%) 3.88600 1.39406 .075 -.2856 8.0576

F2 (GETH 3%) 3.53600 1.39406 .122 -.6356 7.7076

F3 (GETH 5%) 2.17000 1.39406 .540 -2.0016 6.3416

H_19 Basis Gel Carbomer 940 F1( GETH 1%) -5.29400* 1.12732 .001 -8.6674 -1.9206

F2 (GETH 3%) -5.32800* 1.12732 .001 -8.7014 -1.9546 F3 (GETH 5%) -5.95200* 1.12732 .000 -9.3254 -2.5786 Betadine

Salep

-7.49000* 1.12732 .000

-10.8634

-4.1166

F1( GETH 1%) Basis Gel

Carbomer 940

5.29400* 1.12732 .001 1.9206 8.6674


(50)

Lampiran 21. (Lanjutan)

F3 (GETH 5%) -.65800 1.12732 .976 -4.0314 2.7154

Betadine Salep

-2.19600 1.12732 .326 -5.5694 1.1774

F2 (GETH 3%) Basis Gel

Carbomer 940

5.32800* 1.12732 .001 1.9546 8.7014

F1( GETH 1%) .03400 1.12732 1.000 -3.3394 3.4074

F3 (GETH 5%) -.62400 1.12732 .980 -3.9974 2.7494

Betadine Salep

-2.16200 1.12732 .340 -5.5354 1.2114

F3 (GETH 5%) Basis Gel

Carbomer 940

5.95200* 1.12732 .000 2.5786 9.3254

F1( GETH 1%) .65800 1.12732 .976 -2.7154 4.0314

F2 (GETH 3%) .62400 1.12732 .980 -2.7494 3.9974

Betadine Salep

-1.53800 1.12732 .656 -4.9114 1.8354

Betadine Salep Basis Gel

Carbomer 940

7.49000* 1.12732 .000 4.1166 10.8634

F1( GETH 1%) 2.19600 1.12732 .326 -1.1774 5.5694

F2 (GETH 3%) 2.16200 1.12732 .340 -1.2114 5.5354

F3 (GETH 5%) 1.53800 1.12732 .656 -1.8354 4.9114

H_20 Basis Gel Carbomer 940 F1( GETH 1%) -5.29400* .58887 .000 -7.0561 -3.5319

F2 (GETH 3%) -5.29400* .58887 .000 -7.0561 -3.5319 F3 (GETH 5%) -5.29400* .58887 .000 -7.0561 -3.5319 Betadine

Salep

-5.29400* .58887 .000 -7.0561 -3.5319

F1( GETH 1%) Basis Gel

Carbomer 940

5.29400* .58887 .000 3.5319 7.0561

F2 (GETH 3%) .00000 .58887 1.000 -1.7621 1.7621

F3 (GETH 5%) .00000 .58887 1.000 -1.7621 1.7621

Betadine Salep

.00000 .58887 1.000 -1.7621 1.7621

F2 (GETH 3%) Basis Gel

Carbomer 940


(51)

Lampiran 21. (Lanjutan)

F1( GETH 1%) .00000 .58887 1.000 -1.7621 1.7621

F3 (GETH 5%) .00000 .58887 1.000 -1.7621 1.7621

Betadine Salep

.00000 .58887 1.000 -1.7621 1.7621

F3 (GETH 5%) Basis Gel

Carbomer 940

5.29400* .58887 .000 3.5319 7.0561

F1( GETH 1%) .00000 .58887 1.000 -1.7621 1.7621

F2 (GETH 3%) .00000 .58887 1.000 -1.7621 1.7621

Betadine Salep

.00000 .58887 1.000 -1.7621 1.7621

Betadine Salep Basis Gel

Carbomer 940

5.29400* .58887 .000 3.5319 7.0561

F1( GETH 1%) .00000 .58887 1.000 -1.7621 1.7621

F2 (GETH 3%) .00000 .58887 1.000 -1.7621 1.7621

F3 (GETH 5%) .00000 .58887 1.000 -1.7621 1.7621

H_21 Basis Gel Carbomer 940 F1( GETH 1%) -2.70000* .74565 .013 -4.9313 -.4687

F2 (GETH 3%) -2.70000* .74565 .013 -4.9313 -.4687 F3 (GETH 5%) -2.70000* .74565 .013 -4.9313 -.4687 Betadine

Salep

-2.70000* .74565 .013 -4.9313 -.4687

F1( GETH 1%) Basis Gel

Carbomer 940

2.70000* .74565 .013 .4687 4.9313

F2 (GETH 3%) .00000 .74565 1.000 -2.2313 2.2313

F3 (GETH 5%) .00000 .74565 1.000 -2.2313 2.2313

Betadine Salep

.00000 .74565 1.000 -2.2313 2.2313

F2 (GETH 3%) Basis Gel

Carbomer 940

2.70000* .74565 .013 .4687 4.9313

F1( GETH 1%) .00000 .74565 1.000 -2.2313 2.2313

F3 (GETH 5%) .00000 .74565 1.000 -2.2313 2.2313

Betadine Salep


(52)

Lampiran 21. (Lanjutan)

F3 (GETH 5%) Basis Gel

Carbomer 940

2.70000* .74565 .013 .4687 4.9313

F1( GETH 1%) .00000 .74565 1.000 -2.2313 2.2313

F2 (GETH 3%) .00000 .74565 1.000 -2.2313 2.2313

Betadine Salep

.00000 .74565 1.000 -2.2313 2.2313

Betadine Salep Basis Gel

Carbomer 940

2.70000* .74565 .013 .4687 4.9313

F1( GETH 1%) .00000 .74565 1.000 -2.2313 2.2313

F2 (GETH 3%) .00000 .74565 1.000 -2.2313 2.2313

F3 (GETH 5%) .00000 .74565 1.000 -2.2313 2.2313

H_22 Basis Gel Carbomer 940 F1( GETH 1%) -1.70000 .57966 .056 -3.4345 .0345

F2 (GETH 3%) -1.70000 .57966 .056 -3.4345 .0345

F3 (GETH 5%) -1.70000 .57966 .056 -3.4345 .0345

Betadine Salep

-1.70000 .57966 .056 -3.4345 .0345

F1( GETH 1%) Basis Gel

Carbomer 940

1.70000 .57966 .056 -.0345 3.4345

F2 (GETH 3%) .00000 .57966 1.000 -1.7345 1.7345

F3 (GETH 5%) .00000 .57966 1.000 -1.7345 1.7345

Betadine Salep

.00000 .57966 1.000 -1.7345 1.7343

F2 (GETH 3%) Basis Gel

Carbomer 940

1.70000 .57966 .056 -.0345 3.4345

F1( GETH 1%) .00000 .57966 1.000 -1.7345 1.7345

F3 (GETH 5%) .00000 .57966 1.000 -1.7345 1.7345

Betadine Salep

.00000 .57966 1.000 -1.7345 1.7345

F3 (GETH 5%) Basis Gel

Carbomer 940


(53)

Lampiran 21. (Lanjutan)

F1( GETH 1%) .00000 .57966 1.000 -1.7345 1.7345

F2 (GETH 3%) .00000 .57966 1.000 -1.7345 1.7345

Betadine Salep

.00000 .57966 1.000 -1.7345 1.7345

Betadine Salep Basis Gel

Carbomer 940

1.70000 .57966 .056 -.0345 3.4345

F1( GETH 1%) .00000 .57966 1.000 -1.7345 1.7345

F2 (GETH 3%) .00000 .57966 1.000 -1.7345 1.7345

F3 (GETH 5%) .00000 .57966 1.000 -1.7345 1.7345


(1)

Lampiran 21. (Lanjutan)

F2 (GETH 3%) -.37000 1.76550 1.000 -5.6530 4.9130

F3 (GETH 5%) -3.53600 1.76550 .300 -8.8190 1.7470

Betadine Salep

-6.76200* 1.76550 .008

-12.0450

-1.4790

F2 (GETH 3%) Basis Gel

Carbomer 940

4.88000 1.76550 .079 -.4030 10.1630

F1( GETH 1%) .37000 1.76550 1.000 -4.9130 5.6530

F3 (GETH 5%) -3.16600 1.76550 .404 -8.4490 2.1170

Betadine Salep

-6.39200* 1.76550 .013

-11.6750

-1.1090

F3 (GETH 5%) Basis Gel

Carbomer 940

8.04600* 1.76550 .002 2.7630 13.3290

F1( GETH 1%) 3.53600 1.76550 .300 -1.7470 8.8190

F2 (GETH 3%) 3.16600 1.76550 .404 -2.1170 8.4490

Betadine Salep

-3.22600 1.76550 .386 -8.5090 2.0570

Betadine Salep Basis Gel

Carbomer 940

11.27200* 1.76550 .000 5.9890 16.5550

F1( GETH 1%) 6.76200* 1.76550 .008 1.4790 12.0450 F2 (GETH 3%) 6.39200* 1.76550 .013 1.1090 11.6750

F3 (GETH 5%) 3.22600 1.76550 .386 -2.0570 8.5090

H_18 Basis Gel Carbomer 940 F1( GETH 1%) -5.89600* 1.39406 .003

-10.0676

-1.7244

F2 (GETH 3%) -6.24600* 1.39406 .002

-10.4176

-2.0744

F3 (GETH 5%) -7.61200* 1.39406 .000

-11.7836


(2)

Lampiran 21. (Lanjutan)

Betadine Salep

-9.78200* 1.39406 .000

-13.9536

-5.6104

F1( GETH 1%) Basis Gel

Carbomer 940

5.89600* 1.39406 .003 1.7244 10.0676

F2 (GETH 3%) -.35000 1.39406 .999 -4.5216 3.8216

F3 (GETH 5%) -1.71600 1.39406 .734 -5.8876 2.4556

Betadine Salep

-3.88600 1.39406 .075 -8.0576 .2856

F2 (GETH 3%) Basis Gel

Carbomer 940

6.24600* 1.39406 .002 2.0744 10.4176

F1( GETH 1%) .35000 1.39406 .999 -3.8216 4.5216

F3 (GETH 5%) -1.36600 1.39406 .861 -5.5376 2.8056

Betadine Salep

-3.53600 1.39406 .122 -7.7076 .6356

F3 (GETH 5%) Basis Gel

Carbomer 940

7.61200* 1.39406 .000 3.4404 11.7836

F1( GETH 1%) 1.71600 1.39406 .734 -2.4556 5.8876

F2 (GETH 3%) 1.36600 1.39406 .861 -2.8056 5.5376

Betadine Salep

-2.17000 1.39406 .540 -6.3416 2.0016

Betadine Salep Basis Gel

Carbomer 940

9.78200* 1.39406 .000 5.6104 13.9536

F1( GETH 1%) 3.88600 1.39406 .075 -.2856 8.0576

F2 (GETH 3%) 3.53600 1.39406 .122 -.6356 7.7076

F3 (GETH 5%) 2.17000 1.39406 .540 -2.0016 6.3416

H_19 Basis Gel Carbomer 940 F1( GETH 1%) -5.29400* 1.12732 .001 -8.6674 -1.9206

F2 (GETH 3%) -5.32800* 1.12732 .001 -8.7014 -1.9546 F3 (GETH 5%) -5.95200* 1.12732 .000 -9.3254 -2.5786 Betadine

Salep

-7.49000* 1.12732 .000

-10.8634

-4.1166

F1( GETH 1%) Basis Gel

Carbomer 940

5.29400* 1.12732 .001 1.9206 8.6674


(3)

Lampiran 21. (Lanjutan)

F3 (GETH 5%) -.65800 1.12732 .976 -4.0314 2.7154

Betadine Salep

-2.19600 1.12732 .326 -5.5694 1.1774

F2 (GETH 3%) Basis Gel

Carbomer 940

5.32800* 1.12732 .001 1.9546 8.7014

F1( GETH 1%) .03400 1.12732 1.000 -3.3394 3.4074

F3 (GETH 5%) -.62400 1.12732 .980 -3.9974 2.7494

Betadine Salep

-2.16200 1.12732 .340 -5.5354 1.2114

F3 (GETH 5%) Basis Gel

Carbomer 940

5.95200* 1.12732 .000 2.5786 9.3254

F1( GETH 1%) .65800 1.12732 .976 -2.7154 4.0314

F2 (GETH 3%) .62400 1.12732 .980 -2.7494 3.9974

Betadine Salep

-1.53800 1.12732 .656 -4.9114 1.8354

Betadine Salep Basis Gel

Carbomer 940

7.49000* 1.12732 .000 4.1166 10.8634

F1( GETH 1%) 2.19600 1.12732 .326 -1.1774 5.5694

F2 (GETH 3%) 2.16200 1.12732 .340 -1.2114 5.5354

F3 (GETH 5%) 1.53800 1.12732 .656 -1.8354 4.9114

H_20 Basis Gel Carbomer 940 F1( GETH 1%) -5.29400* .58887 .000 -7.0561 -3.5319

F2 (GETH 3%) -5.29400* .58887 .000 -7.0561 -3.5319 F3 (GETH 5%) -5.29400* .58887 .000 -7.0561 -3.5319 Betadine

Salep

-5.29400* .58887 .000 -7.0561 -3.5319

F1( GETH 1%) Basis Gel

Carbomer 940

5.29400* .58887 .000 3.5319 7.0561

F2 (GETH 3%) .00000 .58887 1.000 -1.7621 1.7621

F3 (GETH 5%) .00000 .58887 1.000 -1.7621 1.7621

Betadine Salep

.00000 .58887 1.000 -1.7621 1.7621

F2 (GETH 3%) Basis Gel

Carbomer 940


(4)

Lampiran 21. (Lanjutan)

F1( GETH 1%) .00000 .58887 1.000 -1.7621 1.7621

F3 (GETH 5%) .00000 .58887 1.000 -1.7621 1.7621

Betadine Salep

.00000 .58887 1.000 -1.7621 1.7621

F3 (GETH 5%) Basis Gel

Carbomer 940

5.29400* .58887 .000 3.5319 7.0561

F1( GETH 1%) .00000 .58887 1.000 -1.7621 1.7621

F2 (GETH 3%) .00000 .58887 1.000 -1.7621 1.7621

Betadine Salep

.00000 .58887 1.000 -1.7621 1.7621

Betadine Salep Basis Gel

Carbomer 940

5.29400* .58887 .000 3.5319 7.0561

F1( GETH 1%) .00000 .58887 1.000 -1.7621 1.7621

F2 (GETH 3%) .00000 .58887 1.000 -1.7621 1.7621

F3 (GETH 5%) .00000 .58887 1.000 -1.7621 1.7621

H_21 Basis Gel Carbomer 940 F1( GETH 1%) -2.70000* .74565 .013 -4.9313 -.4687

F2 (GETH 3%) -2.70000* .74565 .013 -4.9313 -.4687 F3 (GETH 5%) -2.70000* .74565 .013 -4.9313 -.4687 Betadine

Salep

-2.70000* .74565 .013 -4.9313 -.4687

F1( GETH 1%) Basis Gel

Carbomer 940

2.70000* .74565 .013 .4687 4.9313

F2 (GETH 3%) .00000 .74565 1.000 -2.2313 2.2313

F3 (GETH 5%) .00000 .74565 1.000 -2.2313 2.2313

Betadine Salep

.00000 .74565 1.000 -2.2313 2.2313

F2 (GETH 3%) Basis Gel

Carbomer 940

2.70000* .74565 .013 .4687 4.9313

F1( GETH 1%) .00000 .74565 1.000 -2.2313 2.2313

F3 (GETH 5%) .00000 .74565 1.000 -2.2313 2.2313

Betadine Salep


(5)

Lampiran 21. (Lanjutan)

F3 (GETH 5%) Basis Gel

Carbomer 940

2.70000* .74565 .013 .4687 4.9313

F1( GETH 1%) .00000 .74565 1.000 -2.2313 2.2313

F2 (GETH 3%) .00000 .74565 1.000 -2.2313 2.2313

Betadine Salep

.00000 .74565 1.000 -2.2313 2.2313

Betadine Salep Basis Gel

Carbomer 940

2.70000* .74565 .013 .4687 4.9313

F1( GETH 1%) .00000 .74565 1.000 -2.2313 2.2313

F2 (GETH 3%) .00000 .74565 1.000 -2.2313 2.2313

F3 (GETH 5%) .00000 .74565 1.000 -2.2313 2.2313

H_22 Basis Gel Carbomer 940 F1( GETH 1%) -1.70000 .57966 .056 -3.4345 .0345

F2 (GETH 3%) -1.70000 .57966 .056 -3.4345 .0345

F3 (GETH 5%) -1.70000 .57966 .056 -3.4345 .0345

Betadine Salep

-1.70000 .57966 .056 -3.4345 .0345

F1( GETH 1%) Basis Gel

Carbomer 940

1.70000 .57966 .056 -.0345 3.4345

F2 (GETH 3%) .00000 .57966 1.000 -1.7345 1.7345

F3 (GETH 5%) .00000 .57966 1.000 -1.7345 1.7345

Betadine Salep

.00000 .57966 1.000 -1.7345 1.7343

F2 (GETH 3%) Basis Gel

Carbomer 940

1.70000 .57966 .056 -.0345 3.4345

F1( GETH 1%) .00000 .57966 1.000 -1.7345 1.7345

F3 (GETH 5%) .00000 .57966 1.000 -1.7345 1.7345

Betadine Salep

.00000 .57966 1.000 -1.7345 1.7345

F3 (GETH 5%) Basis Gel

Carbomer 940


(6)

Lampiran 21. (Lanjutan)

F1( GETH 1%) .00000 .57966 1.000 -1.7345 1.7345

F2 (GETH 3%) .00000 .57966 1.000 -1.7345 1.7345

Betadine Salep

.00000 .57966 1.000 -1.7345 1.7345

Betadine Salep Basis Gel

Carbomer 940

1.70000 .57966 .056 -.0345 3.4345

F1( GETH 1%) .00000 .57966 1.000 -1.7345 1.7345

F2 (GETH 3%) .00000 .57966 1.000 -1.7345 1.7345

F3 (GETH 5%) .00000 .57966 1.000 -1.7345 1.7345