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2.3.4: Renal function at presentation Majority of cases 57 had eGFR 60 ml.min.1.73m
2
at presentation table 2.3.4 a. There were 28 of cases in the eGFR range of 30-59 mlmin1.73m
2
; 12 were 15-29mlmin1.73m
2
and 3 were 15mlmin1.73m
2
Table Figure 2.3.4.1. Table 2.3.4a: Impaired renal function in FSGS by year, 2005-2007
Renal function 2005 2006 2007 Total
n n n n eGFR
≥ 60
27 46 64 61 47 61 138 57 eGFR
60 32 54 41 39 30 39 103 43
Total 59 100 105 100 77 100 241 100
2.3.4.1 Renal function at presentation by age In general, there was a higher risk of renal impairment with increasing age Table 2.3.4.1 Figure
2.3.4.1 ab. Table 2.3.4.1: Renal function at presentation by age group for FSGS, 2005-2007
eGFR mlmin1.73m
2
15- 25 25- 35
35- 45 45- 55
55- 65 65 Total
n n n n n n n 90
35 38
16 25 6 14 0 0 0 0 0 0 57
24 60-89
31 34 25 39 11 25 9 36 3 30 2 33 81 33 30-59
20 22 14 22 17 39 10 40 4 40 2 33 67 28 15-29
4 4 9 14 9 20 4 16 2 20 1 17 29 12 15
2 2 0 0 1 2 2 8 1 10 1 17 7 3
Total 92 100 64 100 44 100 25 100 10 100 6 100 241 100
Figure 2.3.4.1a: Renal function at presentation by age group for FSGS, 2005-2007
P e
rc e
nt a
ge
Age group 10
20 30
40 50
60 70
80 90
100 GFR =90
GFR 60-89 GFR 30-59
GFR 15-29 GFR 15
15-25 25-35
35-45 45-55
55-65 =65
Figure 2.3.4.1b: Impaired renal function in FSGS by age group, 2005-2007
Pe rce
n ta
ge
Age group 10
20 30
40 50
60 70
80 eGFR60mlmin
15-25 25-35
35-45 45-55
55-65 =65
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2.3.4.2 Renal function at presentation by gender There were no significant gender differences with respect to renal function at presentation Table
Figure 2.3.4.2. Table 2.3.4.2: Renal function at presentation according to gender for FSGS, 2005-2007
eGFR mlmin1.73m
2
2005 2006 2007 Total Male Female Male Female Male Female Male Female
n n. No. n n n n n. n
90 9 29 4 14 16 28 11 23 7 14 10 34 32 24 25 24
60-89 7 23 7 25 23 40 14 30 21 45 9 30 51 37 30 29
30-59 10 32 11 39 12 20 13 28 12 26 9 30 34 25 33 31
15-29 3 10 5 18 6 10 8 17 6 13 1 3 15 11 14 13
15 2 6 1 4 1 2 1 2 1 2 1 3 4 3 3 3
Total 31 100 28 100 58 100 47 100 47 100 30 100 136 100 105 100
Figure 2.3.4.2: Renal function at presentation according to gender for FSGS, 2005-2007
P rop
or ti
on of
p a
ti e
nt s
gender 10
20 30
40 50
60 70
80 90
100 GFR =90
GFR 60-89 GFR 30-59
GFR 15-29 GFR 15
Male Female
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2.4: Idiopathic Membranous Nephropathy
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