16, 590-607 10, 839-850 377, 1-16 16, 607-609 72, 1425-1439 276, 27441-27448 2, 355-356

Proceedings of MatricesFor IITTEP – ICoMaNSEd 2015 ISBN: 978-602-74204-0-3 Chemistry Page 136

4. Conclusion

The conclusion from this paper is several potential inhibitors for endocytosis and dynamin could be developed. Further absorption need to improve thus will trial References Abban, C. Y.; Bradbury, N. A.; Meneses, P. I. HPV16 and BPV1 infection can be blocked by the dynamin inhibitior dynasore. American Journal Therapeutics

2008, 15, 304-311

Aridor, M.; Hannan, L. A. Traffic jams. II: An update of diseases of intracellular transport. Traffic

2002, 3, 781-790.

Aridor, M.; Hannan, L. A. Traffic jam: A compendium of human disease that affect intracelular transport processes. Traffic

2000, 1, 836-851

Bitoun, M.; Maugenre, S.; Jeannet, P. Y.; Lacene, E.; Ferrer, X.; Laforet, P.; Martin, J. L.; Laporte, J.; Locmueller, H.; Beggs, A. H.; Fardeau, M.; Eymard, B.; Romero, N. B.; Guicheney, P. Mutations in dynamin 2 cause dominant centronuclear myopathy. Nature Genetics

2005, 37, 1207-1209

Conner, S. D.; Schmid, S. L. Differential requirements for AP-2 in clathrin-mediated endocytosis. Journal of Cell Biology

2003, 162, 773-779.

Cousin, M. A.; Robinson, P. J. The dephosphins: Dephosphorylation by calcineurin triggers synaptic vesicle endocytosis. Trends in Neurosciences

2001, 24, 659-665

Hill, T. A.; Odell, L. R.; Edwards, J. K.; Graham, M. E.; McGeachie, A. A.; Rusak, J.; Quan, A.; Abagyan, R.; Scott, J. L.; Robinson, P. J.; McCluskey, A. Small molecule inhibitors of dynamin I GTPase activity. Journal of Medicinal Chemistry

2005, 48, 7781-7788.

Hill, T. A.; Odell, L. R.; Quan, A.; Ferguson, G.; Robinson, P. J.; McCluskey, A. Long chain amines and long chain ammonium salts as novel inhibitors of dynamin GTPase activity. Bioorganic and Medicinal Chemitry Letters

2004, 14, 3275-3278

Liu, J. P.; Robinson, P. J. Dynamin and endocytosis. Endocrine Reviews

1995, 16, 590-607

Macia, E.; Ehrlich, M.; Massol, R.; Boucrot, E.; Brunner, C.; Kirchhausen, T. Dynasore, a cell-permeable inhibitor of dynamin. Development Cell

2006, 10, 839-850

Mousavi, S. A.; Berg, M. T.; Kjeken, R. Clathrin-dependent endocytosis. Biochemical Journal

2004, 377, 1-16

Nankoe, S. R.; Sever, S. Dynasore puts a new spin on dynamin: a surprising dual role during vesicle formation. Trends in Cell Biology

2006, 16, 607-609

Odell, L.R., Howan, D., Gordon, C.P., Robertson, M.J., Chau, N., Mariana, A., Whiting, A.E., Abagyan, R., Daniel, J.A., Gorgani, N.N., Robinson, P.J., McCluskey, A. The Pthaladyns: GTP Competitive Inhibitors of Dynamin I and II GTPase Derived from Virtual Screening. Journal of Medicinal Chemistry, 2010, 53, 5267-5280 Quan, A.; McGeachie, A. A.; Keating, D. J.; Van Dam, E. M.; Rusak, J.; Chau, N.; Malladi, C. S.; Chen, C.; McCluskey, A.; Cousin, M. A.; Robinson, P. J. Myristyl trimethyl Proceedings of MatricesFor IITTEP – ICoMaNSEd 2015 ISBN: 978-602-74204-0-3 Chemistry Page 137 ammonium bromide and octadecyl trimethyl ammonium bromide are surface-active small molecule dynamin inhibitors that blocks endocytosis mediated by dynamin I or dynamin II. Molecular Pharmacology

2007, 72, 1425-1439

Sung, J. Y.; Kim, J.; Paik, S. R.; Park, J. H.; Ahn, Y. S.; Chung, K. C. Induction of neuronal cell death by Rab-5A-dependent endocytosis of a-synuclein. Journal of Biological Chemistry

2001, 276, 27441-27448

Thompson, H. M.; McNiven, M. A. Discovery of a new dynasore. Nature Chemical Biology

2006, 2, 355-356

Zuchner, S.; Noureddine, M.; Kennerson, M.; Verhoeven, K.; Claeus, K.; Jonghe, P. D.; Meroy, J.; Oliveira, S. A.; Speer, M. C.; Stegner, J. E.; Walizada, M. Mutations in the plecktrin homology domain of dynamin 2 cause dominant intermediate Charcot- Marie-Tooth disease. Nature Genetics

2005, 37, 289-294