Smoking Gravida Renal Disease Nephropathy Cataract surgery

4. Smoking

 L  UKPDS surprisingly reported that smoking was associated with a reduced 6-year incidence of DR. Compared with never smokers, current smokers had around one third lower incidence. DR progression was also lower in current than in never smokers. This is the first major study to demonstrate any relationship between smoking and DR . Earlier WESDR data did not confirm this relationship. American

5. Gravida

• Ramandeep Sing et all : Diabetic Retinopathy An Update , Indian J.O 2008 May-Jul • Guidelines of the Management Diabetic Retinopathy, Cwealth Australia 2008  Gen  Pregnant women with diabetes twice the risk of developing PDR than non-pregnant women. The cause of DR maybe factors both metabolic and hormonal .  Among women with NPDR at the onset pregnancy , 47 developed increased NPDR and 5 developed PDR during pregnancy, of whom 29 regression postpartum and 50 required laser treatment. Among women with PDR prior to pregnancy ,46 progressed during pregnancy. Therefore, early progressive scatter laser treatment of active neovascularisation is warranted when high-risk characteristics.

6. Renal Disease Nephropathy

 DR is a well established risk factor for the development of Diabetic Nephropathy DN, with a 50 probability that DN will develop within 5 years and a 7 probability that DN will develop within 12 years in patients with existing DR. few report however, show that DN predict to development of progression of DR. In the WESDR , a population based cohort study , either gross proteinuria or microalbuminuria was a marker for PDR.  Gsee gftssk Guidelines of the Management Diabetic Retinopathy, Cwealth Australia , 2008

7. Cataract surgery

 Henricksen 1996 reported that progression of retinopathy occurred in 30 out of the 70 eyes after cataract surgery. Patients who progressed had a significantly higher incidence macular edema than those who did not progress.  Chris Emery 2009 reported A year after phacoemulcification surgery, 28,2 of the eyes that were on operated on developed DR, compared to only 13,8 of nonsurgical eyes. In patients who had the surgery in only one eye, 35,6 of the eyes operated on showed signs of DR progression compared to only 20 of the eyes that weren’t surgically . Henricksen M, Diabetic retinopathy before and after cataract surgery ,BJO1996, 80 Chris Emery . Common Cataract SurgeryAccelerates Diabetic Retina Deterioration , Ophthalmology 07.31. 2009

8. Diabetes duration