Perbandingan Kadar Serum Matrix Metalloproteinase (Mmp)-7 Pada Gastritis H.Pylori Dengan Non H.Pylori
DAFTAR PUSTAKA
1. El-Zimaity HMT. Recent advances in the histopathology of gastritis.
Current Diagnostic Pathology. 2007;13:340-8.
2. Rugge M, Pennelli G, Pilozzi E, Fassan M, Ingravallo G, Russo VM, et al.
Gastritis: the histology report. Digestive and Liver Disease. 2011;
43S:S373–84.
3. Fox JG, Wang TC. Inflammation, atrophy and gastric cancer. J Clin
Invest. 2007b;17:60-9.
4. Cesar ACG, Cury PM, Payao SLM. Comparison of histological and
molecular diagnosis of Helicobacter pylori in benign lesions and gastric
adenocarcinoma. Braz J Microbiol. 2005;36(1):261-6.
5. Banerjee A, Mukhopadhyay AK, Paul S, Bhattacharyya A and Swarnakar
S. Unveiling the Intricacies of Helicobacter pylori-induced Gastric
Inflammation: T Helper cells and Matrix Metalloproteinases at a
Crossroad. In: Mozsik G, editor. Current Topics in Gastritis. Croatia:
InTech Publishers; 2013. Chapter 7.
6. K Awwad , A. Alenezy, M. Taha, Hasan M. Helicobacter pylori
associated chronic gastritis: Endoscopic and pathological findings,
comparative study. March 2014. 6(2), pp.23-28.
7. Rehnberg-Laiho L, Rautelin H, Koskela P, Sarna S, Pukkala E, Aromaa A,
et al. Decreasing prevalence of helicobacter antibodies in Finland, with
reference to the decreasing incidence of gastric cancer. Epidemiol Infect.
2001;126:37-42.
8. Matsukura N, Yamada S, Kato S, Tomtitchong P, Tajiri T, Miki M, et al.
Genetic differences in interleukin-1 betapolymorphisms among four Asian
populations: an analysis of the Asian paradox between H. pylori infection
and gastric cancer incidence. J Exp Clin Cancer Res. 2003; 22: 47-55.
9. Xuan J, Deguchi R, Yanagi H, Ozawa H, Urano T, Ogawa Y, et al.
Relationship between gastric mucosal IL-8 levels and histological gastritis
55
Universitas Sumatera Utara
in patients with Helicobacter pylori infection. Tokai J Exp Clin Med.
2005;30(2):83-8.
10. Andersen LP, Holck S, Janulaityte-Gu¨nther D, Kupcinskas L, Kiudelis G,
Jonaitis L, et al. 2005. Gastric inflammatory markers and interleukins in
patients with functional dyspepsia, with and without Helicobacter pylori
infection.FEMS Immun and Med Microbiol; 44:233–238.
11. Koskensalo S, Mrena J, Wiksten JP, Nordling S, Kokkola A, Hagstrom J,
et al. MMP-7 overexpression is an independent prognostic marker in
gastric cancer. Tumor Biol. 2010; 31: 149-155.
12. S. Georgina, Butler, M. Christopher. Matrix metalloproteinase processing
of signaling molecules to regulate inflamation. Periodontology 2000. Vol
63, 2013; 123-148
13. Caruso R, Fina D, Peluso I, et all. IL-21 Is Highly Produced in
Helicobacter pylori-Infected Gastric Mucosa and Promotes Gelatinases
Synthesis. J Immunol 2007; 178: 5957-5965.
14. Krakowiak MS, Noto JM, PlazueloMB et al. Matrix metalloproteinase-7
restrains Helicobacter pylori-induced gastric inflamation and premalignant
lesions in the stomach by altering macrophage polarization. Oncogene
2014, 1-7.
15. Hellmig S, ott S, Rosenstiel P et al. Genetic Variants in Matrix
metalloproteinase genes are associated with development of gastric ulcer
in H. Pylori infection. AmJ Gastroenterol 2006.
16. Rautelin HI, Oksanen AM, Veijola LI et al. Enhanced systemic matrix
metalloproteinase response in Helicobacter pylori gastritis. AnnMed,
2009; 41: 208-215.
17. Toljamo K. Gastric erosions – clinical significance and pathology.A longterm follow-up study. University of Oulu, Finland:Acta Univ Oul;
2012.hlm 1-80.
18. Hirlan, Gastritis dalam Buku Ajar Ilmu Penyakit Dalam Edisi 5, Internal
Publishing : 2009 ; 509-512.
19. S. Ilyas. Repository. Usu.ac.id 2013.
56
Universitas Sumatera Utara
20. Adibi
P.
Gastritis.
[Diunduh
19
Mei
2014].
Tersedia
dari:
http://med.mui.ac.ir
21. Szoke D. Genetic factors related to the histological and macroscopic
lesions of the stomach. [disertasi]. Budapest: Semmelweis University;
2009. Hlm 7-61.
22. Wehbi M, Acute gastritis Medscape. 2014.
23. Simadibrata M. Dyspepsia and Gastroesophageal Reflux Disease (GERD):
Is There Any Correlation? Acta Med Indones. 2009; 41(4): 222-7.
24. Silva MIG, de Sousa FCF.Gastric ulcer etiology. In: Chai J, editor. Peptic
Ulcer Disease. Shanghai: Intech; 2011. hlm. 3-28.
25. Syam AF, Sadikin M, Wanandi SI, Rani AA. Molecular mechanism on
healing process of peptic ulcer.Acta Med Indones. 2009;41(2):95-8.
26. Brzozowski T. Experimental production of peptic ulcer, gastric damage
and cancer models and their use in pathophysiological studies and
pharmacological
treatment–polish
achievement.J
Phyl
Pharmacol.
2003;54:99-126.
27. Wallace JL. Prostaglandins, NSAIDs, and Gastric Mucosal Protection:
Why Doesn’t the Stomach Digest Itself. American Physiological Society.
Physiol Rev 88: 1547-1565, 2008.
28. Cheung R, Cheng TT, Dong Y, Lin HY, Lai K, Lau CS, et al.
2010.Incidence of gastroduodenal ulcers during treatment with celecoxib
or diclofenac: pooled results from three 12-week trials in Chinese patients
with osteoarthritis or rheumatoid arthritis. Int J Rheum Dis;13(2): 151–7.
29. Chung HW, Lim JB. Role of the tumor microenvironment in the
pathogenesis of gastric carcinoma. World J Gastroenterol 2014; 20(7):
1667-1680.
30. Zakaria Z. The role of interleukin-10 in Helicobacter pylori infection.
Master [Tesis]. Nottingham,UK: University of Nottingham; 2010.hlm. 55.
31. Lew E. Peptic ulcer disease. Greenberger NJ, editor. Current Diagnosis
and Treatment Gastroenterology, Hepatology, and Endoscopy. New York:
McGraw Hill; 2009.hlm.175-83.
57
Universitas Sumatera Utara
32. Zhao X, Wang Q, Qian Y, Song JL,. Ilex kudingcha C.J. Tseng
(Kudingcha) prevents HCl/ethanol induced gastric injury in Sprague
Dawley rats. Molecular Medicine Reports. 2013;7:1613-6.
33. Tanigawa T, Watanabe T, Higuchi K, Machida H, Okazaki H, Yamagami
H, et al. 2009. Lansoprazole, a Proton Pump Inhibitor, Suppresses
Production of Tumor Necrosis Factoralpha and Interleukin-1beta Induced
by Lipopolysaccharide and Helicobacter Pylori Bacterial Components in
Human Monocytic Cells via Inhibition of Activation of Nuclear FactorkappaB and Extracellular Signal-Regulated Kinase. J Clin Biochem Nutr;
45(1):86–92.
34. Lee HJ, Han YM, Kim EH, Kim YJ, Hahm KB. A possible involvement of
Nrf2-mediated heme oxygenase-1 up-regulation in protective effect of the
proton pump inhibitor pantoprazole against indomethacin-induced gastric
damage in rats. BMC Gastroenterol. 2012;12:143.
35. Rakananurak N, Sallapant S, Prueksapanich P, Somanawat K, Klaikaew
N, Rerknimitr R, et al. Aloe vera Improved Gastric Injury on Nonsteroidal
Anti-Inflammatory
Drugs-Induced
Gastropathy
in
Rats.
Thai
J
Gastroenterol. 2013; 14(2):87-92.
36. Eamlamnam K, Patumraj S, Visedopas N, et al. Effects of Aloe vera and
sucralfate on gastric microcirculatory changes, cytokine levels and gastric
ulcer healing in rats. World J Gastroenterol 2006;12:2034-9.
37. Naito Y, Yoshikawa T, Yagi N, Matsuyama K, Yoshida N, Seto K, et al.
Effects of polaprezinc on lipid peroxidation, neutrophil accumulation, and
TNF- expression in rats with aspirin-induced gastric mucosal injury. Dig
Dis Sci. 2001;46:845–51.
38. Jainu M, Devi CSS. Gastroprotective action of Cissus quadrangularis
extract against NSAID induced gastric ulcer: role of proinflammatory
cytokines and oxidative damage. Chem Biol Interact. 2006;161:262–70.
39. Konturek PC, Duda A, Brzozowski T, Konturek SJ, Kwiecien S,
Drozdowicz D, et al. Activation of genes for superoxide dismutase,
interleukin-1beta, tumor necrosis factor-alpha, and intercellular adhesion
58
Universitas Sumatera Utara
molecule-1 during healing of ischemia-reperfusion-induced gastric injury.
Scand J Gastroenterol. 2000;35(5):452-63.
40. Israel DA, Peek RM. Review article: Pathogenesis of Helicobacter pyloriinduced gastric inflammation. Aliment Pharmacol Ther. 2001;15:1271-90.
41. Bodger K, Crabtree JE. Helicobacter pylori and gastric inflammation.
British Med Bull. 1998;54:139-50.
42. Furuta T, El-Omar EM, Xiao F, Shirai N, Takashima M, Sugimura H.
Interleukin 1beta polymorphisms increase risk of hypochlorhydria and
atrophic gastritis and reduce risk of duodenal ulcer recurrence in Japan.
Gastroenterology. 2002;123(1):92-105.
43. Schottelius AJ, Mayo MW, Sartor RB, Baldwin AS. Interleukin-10
signaling blocks inhibitor of kappaB kinase activity and nuclear factor
kappaB DNA binding. J Biol Chem. 1999;274:31868-74.
44. Al-Ashy R, Chakroun I, El-Sabban ME, Homaidan FR.The role of NFkappaB in mediating the anti-inflammatory effects of IL-10 in intestinal
epithelial cells.Cytokine.2006; 36:1-8.
45. Sampieri CL, Cordoba KL, Troche JMR, 2013. Matrix metalloproteinases
and their tissue inhibitors in gastric cancer as molecular markers. Review
Article.Journal of Cancer Research and Therapeutics. 2013.Vol 9-Issue 3.
46. McCaig C, Duval C, Hemers E et al. The role of matrix metalloproteinase7 in redefining the gastric microenvironment in respons to helicobacter
pylori. Gastroenterol 2006.
47. Ashraf GMd, Sheikh IA. Advances in Protein Chemistry: Role of Matrix
Metalloproteinases in Cancer; September 2013.
48. Langers AM, Verspaget HW, Hommes DW, Sier CFM. Single-nucleotide
polymorphisms of matrix metallopreteinases and their inhibitors in
gastrointestinal cancer. World J Gastro oncol, 2011; 3(6): 79-98.
49. Wroblewski LE, Peek RM. Orchestration of Dysregulated Epithelial
Turnover by a Manipulative Pathogen. Cell host & Microbe 2. October
2007. Elsevier Inc.
59
Universitas Sumatera Utara
50. Dahlan
MS.
Statistik
untuk
kedokteran
dan
kesehatan.Salemba
Medika.2012;3:26.
51. Sander GB, Mazzoleni LE, Francesconi CFM, Wortmann AC, Andre E,
Theil A, Piccoli VDC, Da Silva AC, et al. Development and Validation of
a Cross-Cultural Questionnaire to Evaluate Nonuclear Dyspepsia: The
Porto Alegre Dyspeptic Symptoms Questionnaire (PADYQ). Dig Dis Sci,
Vol. 49, Nos 11/12 (November/December 2004).
52. Peek RM, Fiske C, Wilson KT. Role of Innate Immunity in Helicobacter
pylori-Induced Gastric Malignancy. Physiol Rev 2010: 90: 831-858.
53. Pandeya N, Whitmen DC, Australian Cancer Study. Prevalence and
determinants of H.Pylori sero-positivity in the australian community. J
Gastroenterol Hepatology.2011 Aug;26(8);1283-9.
54. Zhu Y, et al. Risk factors and prevalence of H.Pylori infection in
persistent high incidence area of gastric carcinoma in Yangzhong
city.2014. .http://dx.doi.org/10.1155/2014/481365.
55. Seyda T, Derya C, Fusun A, Meliha K. The relationship of helicobacter
pylori positivity with age, sex and ABO/Rhesus blood groups in patients
with gastrointestinal complaints in turkey. Helicobacter, June 2007; 12(3):
244-250
56. Naja F,et al. Helicobacter pylori in Ontario : prevalence and rsik factors.
Jurnal canadian of gastroenterol, 2007;21(8):501-506.
57. Bebb JR, Thomas RJ, Collins HM, et al. Helicobacter pylori upregulates
matrilysin (MMP-7) in epithelial cells in vivo and in vitro in a Cag
dependent manner. Gut 2003; 52: 1408-1413.
58. Crawford HC, Krishna US, Israel DA, et al. Helicobacter pylori StrainSelective Induction of Matrix Metalloproteinase-7 In Vitro and Within
Gastric Mucosa. Gastroenterol 2003; 125: 1125-1136.
59. Rautelin IH, Oksanen AM, Veijola LI, et al. Enhanced systemic matrix
metalloproteinase response in Helicobacter pylori gastritis. Ann Med,
2009; 41(3):208-15.
60
Universitas Sumatera Utara
60. Yin Y, Grabowska AM, Clarke PA, et al. Helicobacter pylori potentiates
epithelial : mesenchymal transition in gastric cancer: links to soluble HBEGF, gastrin and matrix metalloproteinase-7. Gut 2010; 59: 1037-1045.
61. Chung WC, Jung SH, Lee KM, et al. The detection of Helicobacter pylori
cag
pathogenicity
islands
(PAIs)
and
expression
of
matrix
metalloproteinase-7 (MMP-7) in gastric epithelial dysplasia and
intramucosal cancer. Gastric Cancer 2010;13:162-169.
62. Bode G, Rothenbacher D, Brenner H, Adler G. Helicobacter pylori and
abdominal symptoms: a population-based study among preschool children
in southern Germany. Pediatrics 1998;101:634-7.
63. Joshi A, Gupta SD, Ahuja V, Sharma MP. Symptom score does not
correlate with gastritis grade and Helicobacter pylori infection in non ulcer
dyspepsia. Trop Gastroenterol 2001;22:194-6.
64. Kasifoglu N, Akgun Y, Saricam T, Kiremitci A, Tercan. IL-8 Serum level
in patients with Helicobacter pylori infection and relation between
serological markers. African Journal of Microbiology 2009 ;11:822-25.
65. Dandin AS, Jayashree P, Athanikar V.S. H. pylori associated gastritis.
Journal Clin Diag Rsrch, 2012. 6(2): 211-214.
61
Universitas Sumatera Utara
1. El-Zimaity HMT. Recent advances in the histopathology of gastritis.
Current Diagnostic Pathology. 2007;13:340-8.
2. Rugge M, Pennelli G, Pilozzi E, Fassan M, Ingravallo G, Russo VM, et al.
Gastritis: the histology report. Digestive and Liver Disease. 2011;
43S:S373–84.
3. Fox JG, Wang TC. Inflammation, atrophy and gastric cancer. J Clin
Invest. 2007b;17:60-9.
4. Cesar ACG, Cury PM, Payao SLM. Comparison of histological and
molecular diagnosis of Helicobacter pylori in benign lesions and gastric
adenocarcinoma. Braz J Microbiol. 2005;36(1):261-6.
5. Banerjee A, Mukhopadhyay AK, Paul S, Bhattacharyya A and Swarnakar
S. Unveiling the Intricacies of Helicobacter pylori-induced Gastric
Inflammation: T Helper cells and Matrix Metalloproteinases at a
Crossroad. In: Mozsik G, editor. Current Topics in Gastritis. Croatia:
InTech Publishers; 2013. Chapter 7.
6. K Awwad , A. Alenezy, M. Taha, Hasan M. Helicobacter pylori
associated chronic gastritis: Endoscopic and pathological findings,
comparative study. March 2014. 6(2), pp.23-28.
7. Rehnberg-Laiho L, Rautelin H, Koskela P, Sarna S, Pukkala E, Aromaa A,
et al. Decreasing prevalence of helicobacter antibodies in Finland, with
reference to the decreasing incidence of gastric cancer. Epidemiol Infect.
2001;126:37-42.
8. Matsukura N, Yamada S, Kato S, Tomtitchong P, Tajiri T, Miki M, et al.
Genetic differences in interleukin-1 betapolymorphisms among four Asian
populations: an analysis of the Asian paradox between H. pylori infection
and gastric cancer incidence. J Exp Clin Cancer Res. 2003; 22: 47-55.
9. Xuan J, Deguchi R, Yanagi H, Ozawa H, Urano T, Ogawa Y, et al.
Relationship between gastric mucosal IL-8 levels and histological gastritis
55
Universitas Sumatera Utara
in patients with Helicobacter pylori infection. Tokai J Exp Clin Med.
2005;30(2):83-8.
10. Andersen LP, Holck S, Janulaityte-Gu¨nther D, Kupcinskas L, Kiudelis G,
Jonaitis L, et al. 2005. Gastric inflammatory markers and interleukins in
patients with functional dyspepsia, with and without Helicobacter pylori
infection.FEMS Immun and Med Microbiol; 44:233–238.
11. Koskensalo S, Mrena J, Wiksten JP, Nordling S, Kokkola A, Hagstrom J,
et al. MMP-7 overexpression is an independent prognostic marker in
gastric cancer. Tumor Biol. 2010; 31: 149-155.
12. S. Georgina, Butler, M. Christopher. Matrix metalloproteinase processing
of signaling molecules to regulate inflamation. Periodontology 2000. Vol
63, 2013; 123-148
13. Caruso R, Fina D, Peluso I, et all. IL-21 Is Highly Produced in
Helicobacter pylori-Infected Gastric Mucosa and Promotes Gelatinases
Synthesis. J Immunol 2007; 178: 5957-5965.
14. Krakowiak MS, Noto JM, PlazueloMB et al. Matrix metalloproteinase-7
restrains Helicobacter pylori-induced gastric inflamation and premalignant
lesions in the stomach by altering macrophage polarization. Oncogene
2014, 1-7.
15. Hellmig S, ott S, Rosenstiel P et al. Genetic Variants in Matrix
metalloproteinase genes are associated with development of gastric ulcer
in H. Pylori infection. AmJ Gastroenterol 2006.
16. Rautelin HI, Oksanen AM, Veijola LI et al. Enhanced systemic matrix
metalloproteinase response in Helicobacter pylori gastritis. AnnMed,
2009; 41: 208-215.
17. Toljamo K. Gastric erosions – clinical significance and pathology.A longterm follow-up study. University of Oulu, Finland:Acta Univ Oul;
2012.hlm 1-80.
18. Hirlan, Gastritis dalam Buku Ajar Ilmu Penyakit Dalam Edisi 5, Internal
Publishing : 2009 ; 509-512.
19. S. Ilyas. Repository. Usu.ac.id 2013.
56
Universitas Sumatera Utara
20. Adibi
P.
Gastritis.
[Diunduh
19
Mei
2014].
Tersedia
dari:
http://med.mui.ac.ir
21. Szoke D. Genetic factors related to the histological and macroscopic
lesions of the stomach. [disertasi]. Budapest: Semmelweis University;
2009. Hlm 7-61.
22. Wehbi M, Acute gastritis Medscape. 2014.
23. Simadibrata M. Dyspepsia and Gastroesophageal Reflux Disease (GERD):
Is There Any Correlation? Acta Med Indones. 2009; 41(4): 222-7.
24. Silva MIG, de Sousa FCF.Gastric ulcer etiology. In: Chai J, editor. Peptic
Ulcer Disease. Shanghai: Intech; 2011. hlm. 3-28.
25. Syam AF, Sadikin M, Wanandi SI, Rani AA. Molecular mechanism on
healing process of peptic ulcer.Acta Med Indones. 2009;41(2):95-8.
26. Brzozowski T. Experimental production of peptic ulcer, gastric damage
and cancer models and their use in pathophysiological studies and
pharmacological
treatment–polish
achievement.J
Phyl
Pharmacol.
2003;54:99-126.
27. Wallace JL. Prostaglandins, NSAIDs, and Gastric Mucosal Protection:
Why Doesn’t the Stomach Digest Itself. American Physiological Society.
Physiol Rev 88: 1547-1565, 2008.
28. Cheung R, Cheng TT, Dong Y, Lin HY, Lai K, Lau CS, et al.
2010.Incidence of gastroduodenal ulcers during treatment with celecoxib
or diclofenac: pooled results from three 12-week trials in Chinese patients
with osteoarthritis or rheumatoid arthritis. Int J Rheum Dis;13(2): 151–7.
29. Chung HW, Lim JB. Role of the tumor microenvironment in the
pathogenesis of gastric carcinoma. World J Gastroenterol 2014; 20(7):
1667-1680.
30. Zakaria Z. The role of interleukin-10 in Helicobacter pylori infection.
Master [Tesis]. Nottingham,UK: University of Nottingham; 2010.hlm. 55.
31. Lew E. Peptic ulcer disease. Greenberger NJ, editor. Current Diagnosis
and Treatment Gastroenterology, Hepatology, and Endoscopy. New York:
McGraw Hill; 2009.hlm.175-83.
57
Universitas Sumatera Utara
32. Zhao X, Wang Q, Qian Y, Song JL,. Ilex kudingcha C.J. Tseng
(Kudingcha) prevents HCl/ethanol induced gastric injury in Sprague
Dawley rats. Molecular Medicine Reports. 2013;7:1613-6.
33. Tanigawa T, Watanabe T, Higuchi K, Machida H, Okazaki H, Yamagami
H, et al. 2009. Lansoprazole, a Proton Pump Inhibitor, Suppresses
Production of Tumor Necrosis Factoralpha and Interleukin-1beta Induced
by Lipopolysaccharide and Helicobacter Pylori Bacterial Components in
Human Monocytic Cells via Inhibition of Activation of Nuclear FactorkappaB and Extracellular Signal-Regulated Kinase. J Clin Biochem Nutr;
45(1):86–92.
34. Lee HJ, Han YM, Kim EH, Kim YJ, Hahm KB. A possible involvement of
Nrf2-mediated heme oxygenase-1 up-regulation in protective effect of the
proton pump inhibitor pantoprazole against indomethacin-induced gastric
damage in rats. BMC Gastroenterol. 2012;12:143.
35. Rakananurak N, Sallapant S, Prueksapanich P, Somanawat K, Klaikaew
N, Rerknimitr R, et al. Aloe vera Improved Gastric Injury on Nonsteroidal
Anti-Inflammatory
Drugs-Induced
Gastropathy
in
Rats.
Thai
J
Gastroenterol. 2013; 14(2):87-92.
36. Eamlamnam K, Patumraj S, Visedopas N, et al. Effects of Aloe vera and
sucralfate on gastric microcirculatory changes, cytokine levels and gastric
ulcer healing in rats. World J Gastroenterol 2006;12:2034-9.
37. Naito Y, Yoshikawa T, Yagi N, Matsuyama K, Yoshida N, Seto K, et al.
Effects of polaprezinc on lipid peroxidation, neutrophil accumulation, and
TNF- expression in rats with aspirin-induced gastric mucosal injury. Dig
Dis Sci. 2001;46:845–51.
38. Jainu M, Devi CSS. Gastroprotective action of Cissus quadrangularis
extract against NSAID induced gastric ulcer: role of proinflammatory
cytokines and oxidative damage. Chem Biol Interact. 2006;161:262–70.
39. Konturek PC, Duda A, Brzozowski T, Konturek SJ, Kwiecien S,
Drozdowicz D, et al. Activation of genes for superoxide dismutase,
interleukin-1beta, tumor necrosis factor-alpha, and intercellular adhesion
58
Universitas Sumatera Utara
molecule-1 during healing of ischemia-reperfusion-induced gastric injury.
Scand J Gastroenterol. 2000;35(5):452-63.
40. Israel DA, Peek RM. Review article: Pathogenesis of Helicobacter pyloriinduced gastric inflammation. Aliment Pharmacol Ther. 2001;15:1271-90.
41. Bodger K, Crabtree JE. Helicobacter pylori and gastric inflammation.
British Med Bull. 1998;54:139-50.
42. Furuta T, El-Omar EM, Xiao F, Shirai N, Takashima M, Sugimura H.
Interleukin 1beta polymorphisms increase risk of hypochlorhydria and
atrophic gastritis and reduce risk of duodenal ulcer recurrence in Japan.
Gastroenterology. 2002;123(1):92-105.
43. Schottelius AJ, Mayo MW, Sartor RB, Baldwin AS. Interleukin-10
signaling blocks inhibitor of kappaB kinase activity and nuclear factor
kappaB DNA binding. J Biol Chem. 1999;274:31868-74.
44. Al-Ashy R, Chakroun I, El-Sabban ME, Homaidan FR.The role of NFkappaB in mediating the anti-inflammatory effects of IL-10 in intestinal
epithelial cells.Cytokine.2006; 36:1-8.
45. Sampieri CL, Cordoba KL, Troche JMR, 2013. Matrix metalloproteinases
and their tissue inhibitors in gastric cancer as molecular markers. Review
Article.Journal of Cancer Research and Therapeutics. 2013.Vol 9-Issue 3.
46. McCaig C, Duval C, Hemers E et al. The role of matrix metalloproteinase7 in redefining the gastric microenvironment in respons to helicobacter
pylori. Gastroenterol 2006.
47. Ashraf GMd, Sheikh IA. Advances in Protein Chemistry: Role of Matrix
Metalloproteinases in Cancer; September 2013.
48. Langers AM, Verspaget HW, Hommes DW, Sier CFM. Single-nucleotide
polymorphisms of matrix metallopreteinases and their inhibitors in
gastrointestinal cancer. World J Gastro oncol, 2011; 3(6): 79-98.
49. Wroblewski LE, Peek RM. Orchestration of Dysregulated Epithelial
Turnover by a Manipulative Pathogen. Cell host & Microbe 2. October
2007. Elsevier Inc.
59
Universitas Sumatera Utara
50. Dahlan
MS.
Statistik
untuk
kedokteran
dan
kesehatan.Salemba
Medika.2012;3:26.
51. Sander GB, Mazzoleni LE, Francesconi CFM, Wortmann AC, Andre E,
Theil A, Piccoli VDC, Da Silva AC, et al. Development and Validation of
a Cross-Cultural Questionnaire to Evaluate Nonuclear Dyspepsia: The
Porto Alegre Dyspeptic Symptoms Questionnaire (PADYQ). Dig Dis Sci,
Vol. 49, Nos 11/12 (November/December 2004).
52. Peek RM, Fiske C, Wilson KT. Role of Innate Immunity in Helicobacter
pylori-Induced Gastric Malignancy. Physiol Rev 2010: 90: 831-858.
53. Pandeya N, Whitmen DC, Australian Cancer Study. Prevalence and
determinants of H.Pylori sero-positivity in the australian community. J
Gastroenterol Hepatology.2011 Aug;26(8);1283-9.
54. Zhu Y, et al. Risk factors and prevalence of H.Pylori infection in
persistent high incidence area of gastric carcinoma in Yangzhong
city.2014. .http://dx.doi.org/10.1155/2014/481365.
55. Seyda T, Derya C, Fusun A, Meliha K. The relationship of helicobacter
pylori positivity with age, sex and ABO/Rhesus blood groups in patients
with gastrointestinal complaints in turkey. Helicobacter, June 2007; 12(3):
244-250
56. Naja F,et al. Helicobacter pylori in Ontario : prevalence and rsik factors.
Jurnal canadian of gastroenterol, 2007;21(8):501-506.
57. Bebb JR, Thomas RJ, Collins HM, et al. Helicobacter pylori upregulates
matrilysin (MMP-7) in epithelial cells in vivo and in vitro in a Cag
dependent manner. Gut 2003; 52: 1408-1413.
58. Crawford HC, Krishna US, Israel DA, et al. Helicobacter pylori StrainSelective Induction of Matrix Metalloproteinase-7 In Vitro and Within
Gastric Mucosa. Gastroenterol 2003; 125: 1125-1136.
59. Rautelin IH, Oksanen AM, Veijola LI, et al. Enhanced systemic matrix
metalloproteinase response in Helicobacter pylori gastritis. Ann Med,
2009; 41(3):208-15.
60
Universitas Sumatera Utara
60. Yin Y, Grabowska AM, Clarke PA, et al. Helicobacter pylori potentiates
epithelial : mesenchymal transition in gastric cancer: links to soluble HBEGF, gastrin and matrix metalloproteinase-7. Gut 2010; 59: 1037-1045.
61. Chung WC, Jung SH, Lee KM, et al. The detection of Helicobacter pylori
cag
pathogenicity
islands
(PAIs)
and
expression
of
matrix
metalloproteinase-7 (MMP-7) in gastric epithelial dysplasia and
intramucosal cancer. Gastric Cancer 2010;13:162-169.
62. Bode G, Rothenbacher D, Brenner H, Adler G. Helicobacter pylori and
abdominal symptoms: a population-based study among preschool children
in southern Germany. Pediatrics 1998;101:634-7.
63. Joshi A, Gupta SD, Ahuja V, Sharma MP. Symptom score does not
correlate with gastritis grade and Helicobacter pylori infection in non ulcer
dyspepsia. Trop Gastroenterol 2001;22:194-6.
64. Kasifoglu N, Akgun Y, Saricam T, Kiremitci A, Tercan. IL-8 Serum level
in patients with Helicobacter pylori infection and relation between
serological markers. African Journal of Microbiology 2009 ;11:822-25.
65. Dandin AS, Jayashree P, Athanikar V.S. H. pylori associated gastritis.
Journal Clin Diag Rsrch, 2012. 6(2): 211-214.
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