Pengolahan Data Analisis Data

2. Pemeriksaan antigen NS1 perlu dilakukan secara rutin karena dapat mendiagnosis pasien pada fase awal penyakit. 3. Peneliti selanjutnya dapat menganalisis hubungan hasil pemeriksaan NS1 terhadap parameter diagnosis infeksi dengue lainnya, seperti hematokrit, hemoglobin dan leukosit. 4. Peneliti selanjutnya dapat menganalisis hubungan hasil pemeriskaan NS1 terhadap masing-masing gejalatanda klinis infeksi dengue. DAFTAR PUSTAKA Ahmed NH Shobha B. 2014. Comparison of NS1 antigen detection ELISA, real time RT-PCR and virus isolation for rapid diagnosis of dengue infection in acute phase. J Vector Borne.Dis. 51:194-9 Alcon S, Talarmin A, Debruyne M, Falconar A, Deubel V, Flamand M. 2002. Enzyme-linked immunosorbent assay specific to dengue virus type 1 non- structural protein NS1 reveals circulation of the antigen in the blood during the acute phase of disease in patients experiencing primary or secondary infections. J Clin Microbiol. 40:376-81 Avirutnan P, Punyadee N, Noisakran S, Komoltri C, Thiemmeca S, Auethavornanan K, et al. 2006. Vascular leakage in severe dengue virus infections: a potential role for the nonstructural viral protein NS1 and complement. J Infect Dis. 193:1078-88 Behrman RE, Kliegman RM, Arvin AM. 2000. Ilmu kesehatan anak nelson. Edisi 15. Vol. 2. Jakarta: EGC Badave GK, Swaroop PA, Rao PN. 2015. Importance of NS1 antigen detection and its association with platelet count for early diagnosis of dengue virus infection. Int J Curr Microbiol App Sci. 43:779-84. Bhatt S, Peter WG, Oliver JB, Jane PM, Andrew WF, Catherine LM, et al. 2013. The global distribution and burden of dengue. Nature. 7446:504-7. Tersedia dari: http:doi.org10.1038nature12060 Candra A. 2010. Demam berdarah dengue: epidemiologi , patogenesis , dan faktor risiko penularan dengue hemorrhagic fever. Aspirator. 22:110-9 Cheng HJ, Lei HY, Lin CF, Luo YH, Wan SW, Liu HS, et al. 2009. Anti-dengue virus nonstructural protein 1 antibodies recognize protein disulfide isomerase on platelets and inhibit platelet aggregation. Molecular Immun. 47:398–406. Clyde K, Kyle JL, Harris E. 2006. Recent advances in deciphering viral and host determinants of dengue virus replication and pathogenesis. Journal of Virology. 8023:11418-31