Canesten HC c (Bayer Consumer Care) A HYDROCORTISONE BUTYRATE

1 Canesten HC c (Bayer Consumer Care) A HYDROCORTISONE BUTYRATE

Cream , hydrocortisone 1%, clotrimazole 1%, net price Indications severe inflammatory skin disorders such

30 g = £2.42. Label: 28, counselling, application, see as eczemas unresponsive to less potent corticoster- p. 623. Potency: mild Excipients include benzyl alcohol, cetostearyl alcohol

oids; psoriasis, see notes above Cautions see notes above

1. A 15-g tube is on sale to the public for the treatment of athlete’s foot and fungal infection of skin folds with

Contra-indications see notes above associated inflammation

Side-effects see notes above

BNF 57

13.4 Topical corticosteroids 625

Dose Betamethasone Valerate (Non-proprietary) A . Apply thinly 1–2 times daily

Cream , betamethasone (as valerate) 0.1%, net price

30 g = £1.63, 100 g = £4.36. Label: 28, counselling, Locoid c (Astellas) A application, see p. 623. Potency: potent Cream , hydrocortisone butyrate 0.1%, net price 30 g =

Ointment £2.29, 100 g = £7.05. Label: 28, counselling, applica- , betamethasone (as valerate) 0.1%, net price 30 g = £1.70, 100 g = £4.15. Label: 28, counsel- tion, see p. 623. Potency: potent Excipients include cetostearyl alcohol, hydroxybenzoates (parabens)

ling, application, see p. 623. Potency: potent Lipocream , hydrocortisone butyrate 0.1%, net price

Betacap c (Dermal) A

30 g = £2.41, 100 g = £7.38. Label: 28, counselling, Scalp application , betamethasone (as valerate) 0.1% application, see p. 623. Potency: potent

in a water-miscible basis containing coconut oil deri-

Excipients include benzyl alcohol, cetostearyl alcohol, hydroxybenzo- ates (parabens)

vative, net price 100 mL = £3.92. Label: 15, 28, Note For bland cream basis see Lipobase , section 13.2.1

counselling, application, see p. 623. Potency: potent Excipients none as listed in section 13.1.3

Ointment , hydrocortisone butyrate 0.1%, net price Betnovate 30 g = £2.29, 100 g = £7.05. Label: 28, counselling, c (GSK) A application, see p. 623. Potency: potent

Cream , betamethasone (as valerate) 0.1% in a water-

miscible basis, net price 30 g = £1.43, 100 g = £4.05. Scalp lotion , hydrocortisone butyrate 0.1%, in an

Excipients none as listed in section 13.1.3

Label: 28, counselling, application, see p. 623. aqueous isopropyl alcohol basis, net price 100 mL =

Potency: potent

Excipients £9.76. Label: 15, 28, counselling, application, see include cetostearyl alcohol, chlorocresol p. 623. Potency: potent

Ointment , betamethasone (as valerate) 0.1% in an

Excipients none as listed in section 13.1.3

anhydrous paraffin basis, net price 30 g = £1.43, 100 g = £4.05. Label: 28, counselling, application, see p. 623. Locoid Crelo c (Astellas) A Potency: potent

Lotion (topical emulsion), hydrocortisone butyrate

Excipients none as listed in section 13.1.3

0.1% in a water-miscible basis, net price 100 g (with Lotion , betamethasone (as valerate) 0.1%, net price applicator nozzle) = £8.44. Label: 28, counselling,

100 mL = £4.86. Label: 28, counselling, application, application, see p. 623. Potency: potent

see p. 623. Potency: potent

Excipients include butylated hydroxytoluene, cetostearyl alcohol, Excipients include cetostearyl alcohol, hydroxybenzoates (parabens) hydroxybenzoates (parabens), propylene glycol

Scalp application , betamethasone (as valerate) 0.1% in a water-miscible basis, net price 100 mL = £5.30. Label: 15, 28, counselling, application, see p. 623.

ALCLOMETASONE DIPROPIONATE Potency: potent

Excipients none as listed in section 13.1.3

Indications inflammatory skin disorders such as Betnovate-RD c (GSK) A eczemas

Cream , betamethasone (as valerate) 0.025% in a Cautions see notes above

water-miscible basis (1 in 4 dilution of Betnovate c

Contra-indications see notes above cream), net price 100 g = £3.34. Label: 28, counselling, Side-effects see notes above

application, see p. 623. Potency: moderate Excipients include cetostearyl alcohol, chlorocresol

Dose Ointment , betamethasone (as valerate) 0.025% in an . Apply thinly 1–2 times daily

anhydrous paraffin basis (1 in 4 dilution of Betnovate c

ointment), net price 100 g = £3.34. Label: 28, (PLIVA) A counselling, application, see p. 623. Potency: moder-

Modrasone c

Cream , alclometasone dipropionate 0.05%, net price

ate

50 g = £2.68. Label: 28, counselling, application, see

Excipients none as listed in section 13.1.3

p. 623. Potency: moderate Excipients include cetostearyl alcohol, chlorocresol, propylene glycol

Bettamousse c (UCB Pharma) A Skin

Ointment , alclometasone dipropionate 0.05%, net Foam (= scalp application), betamethasone valerate price 50 g = £2.68. Label: 28, counselling, application,

0.12% (: betamethasone 0.1%), net price 100 g = see p. 623. Potency: moderate

£9.75. Label: 28, counselling, application, see p. 623.

Excipients include beeswax, propylene glycol

Potency: potent Excipients include cetyl alcohol, polysorbate 60, propylene glycol, stearyl alcohol Note Flammable

Diprosone c (Schering-Plough) A Cream Indications , betamethasone (as dipropionate) 0.05%, net

BETAMETHASONE ESTERS

severe inflammatory skin disorders such price 30 g = £2.24, 100 g = £6.36. Label: 28, counsel- as eczemas unresponsive to less potent corticoster-

ling, application, see p. 623. Potency: potent oids; psoriasis, see notes above

Excipients include cetostearyl alcohol, chlorocresol

Cautions see notes above; use of more than 100 g per Ointment , betamethasone (as dipropionate) 0.05%, week of 0.1% preparation likely to cause adrenal

net price 30 g = £2.24, 100 g = £6.36. Label: 28, suppression

counselling, application, see p. 623. Potency: potent Contra-indications see notes above

Excipients none as listed in section 13.1.3

Side-effects see notes above Lotion , betamethasone (as dipropionate) 0.05%, net Dose

price 30 mL = £2.83, 100 mL = £8.10. Label: 28, counselling, application, see p. 623. Potency: potent

. Apply thinly 1–2 times daily

Excipients none as listed in section 13.1.3

13.4 Topical corticosteroids BNF 57 With salicylic acid

Clarelux c (Fabre) A See notes above for comment on compound preparations

Foam (= scalp application), clobetasol propionate Diprosalic c (Schering-Plough) A 0.05%, net price 100 g = £11.06. Label: 15, 28, coun-

Ointment , betamethasone (as dipropionate) 0.05%, selling, application, see p. 623. Potency: very potent salicylic acid 3%, net price 30 g = £3.30, 100 g = £9.50. Excipients

stearyl alcohol include cetyl alcohol, polysorbate 60, propylene glycol,

Label: 28, counselling, application, see p. 623. Caution flammable Potency: potent

Note Apply directly to scalp lesions (foam begins to subside

Excipients none as listed in section 13.1.3 immediately on contact with skin) Dose apply thinly 1–2 times daily; max. 60 g per week

Scalp application , betamethasone (as dipropionate) Dermovate c (GSK) A 0.05%, salicylic acid 2%, in an alcoholic basis, net

Cream , clobetasol propionate 0.05%, net price 30 g = price 100 mL = £10.50. Label: 28, counselling, appli-

£2.86, 100 g = £8.39. Label: 28, counselling, applica- cation, see p. 623. Potency: potent

tion, see p. 623. Potency: very potent

Excipients include disodium edetate Excipients include beeswax (or beeswax substitute), cetostearyl Dose apply a few drops 1–2 times daily

alcohol, chlorocresol, propylene glycol Ointment , clobetasol propionate 0.05%, net price 30 g

With antimicrobials = £2.86, 100 g = £8.39. Label: 28, counselling, appli- See notes above for comment on compound preparations

cation, see p. 623. Potency: very potent

c Excipients Betnovate-C include propylene glycol (Chemidex) A Scalp application , clobetasol propionate 0.05%, in a Cream , betamethasone (as valerate) 0.1%, clioquinol

thickened alcoholic basis, net price 30 mL = £3.26, 3%, net price 30 g = £1.76. Label: 28, counselling,

100 mL = £11.06. Label: 15, 28, counselling, applica- application, see p. 623. Potency: potent Excipients include cetostearyl alcohol, chlorocresol

tion, see p. 623. Potency: very potent Excipients

Note Stains clothing none as listed in section 13.1.3

Ointment , betamethasone (as valerate) 0.1%, clio- Etrivex c (Galderma) A quinol 3%, net price 30 g = £1.76. Label: 28, coun-

Shampoo , clobetasol propionate 0.05%, net price selling, application, see p. 623. Potency: potent

125 mL = £11.94. Label: 28, counselling, application,

Excipients none as listed in section 13.1.3

see p. 623. Potency: very potent Note Stains clothing

Excipients none as listed in section 13.1.3

c Dose moderate scalp psoriasis, ADULT Betnovate-N over 18 years, apply thinly (Chemidex) A once daily, rinse off after 15 minutes; reduce frequency of appli- Cream , betamethasone (as valerate) 0.1%, neomycin

cation after clinical improvement; max. duration of treatment 4 sulphate 0.5%, net price 30 g = £1.76, 100 g = £4.88.

weeks

Label: 28, counselling, application, see p. 623. Potency: potent Excipients include cetostearyl alcohol, chlorocresol Ointment , betamethasone (as valerate) 0.1%, neo-

CLOBETASONE BUTYRATE

mycin sulphate 0.5%, net price 30 g = £1.76, 100 g = Indications eczemas and dermatitis of all types; £4.88. Label: 28, counselling, application, see p. 623.

maintenance between courses of more potent corti- Potency: potent Excipients none as listed in section 13.1.3

costeroids Cautions see notes above Fucibet c (LEO) A Contra-indications see notes above

Cream , betamethasone (as valerate) 0.1%, fusidic acid

2%, net price 30 g = £5.62, 60 g = £11.23. Label: 28, see notes above counselling, application, see p. 623. Potency: potent

Side-effects

Dose

Skin

Excipients include cetostearyl alcohol, chlorocresol

. Apply thinly 1–2 times daily Lipid cream , betamethasone (as valerate) 0.1%, fusi-

1 13 c dic acid 2%, net price 30 g = £5.62. Label: 28, coun- Eumovate (GSK) A selling, application, see p. 623. Potency: potent

Cream , clobetasone butyrate 0.05%, net price 30 g =

Excipients include cetostearyl alcohol, hydroxybenzoates (parabens)

£1.97, 100 g = £5.77. Label: 28, counselling, applica- tion, see p. 623. Potency: moderate Lotriderm c (PLIVA) A Excipients include beeswax substitute, cetostearyl alcohol, chlorocresol

Cream , betamethasone dipropionate 0.064% (: Ointment , clobetasone butyrate 0.05%, net price 30 g betamethasone 0.05%), clotrimazole 1%, net price

= £1.97, 100 g = £5.77. Label: 28, counselling, appli-

30 g = £6.34. Label: 28, counselling, application, see cation, see p. 623. Potency: moderate p. 623. Potency: potent

Excipients none as listed in section 13.1.3 Excipients include benzyl alcohol, cetostearyl alcohol, propylene glycol

1. Cream can be sold to the public for short-term symptomatic treatment and control of patches of eczema and dermatitis (but not seborrhoeic dermatitis) in adults and children over

12 years provided pack does not contain more than 15 g Indications short-term treatment only of severe

CLOBETASOL PROPIONATE

resistant inflammatory skin disorders such as recal- With antimicrobials citrant eczemas unresponsive to less potent corti-

See notes above for comment on compound preparations costeroids; psoriasis, see notes above

Trimovate c Cautions (GSK) A see notes above

Cream , clobetasone butyrate 0.05%, oxytetracycline Contra-indications see notes above

3% (as calcium salt), nystatin 100 000 units/g, net Side-effects see notes above

price 30 g = £3.49. Label: 28, counselling, application, Dose

see p. 623. Potency: moderate . Apply thinly 1–2 times daily for up to 4 weeks; max.

Excipients include cetostearyl alcohol, chlorocresol, sodium metabi- sulphite

50 g of 0.05% preparation per week Note Stains clothing

BNF 57

13.4 Topical corticosteroids 627