156 S. Mazaki-Tovi et al.

156 S. Mazaki-Tovi et al.

173. Schieve LA, Handler A: Preterm delivery and perinatal death among significance of amniotic fluid ‘sludge’ in patients with preterm labor black and white infants in a Chicago-area perinatal registry. Obstet

and intact membranes. Ultrasound Obstet Gynecol 25:346-352, 2005 Gynecol 88:356-363, 1996

195. Jacobsson B, Mattsby-Baltzer I, Andersch B, et al: Microbial invasion 174. Blackmore CA, Savitz DA, Edwards LJ, et al: Racial differences in the

and cytokine response in amniotic fluid in a Swedish population of patterns of preterm delivery in central North Carolina, USA. Paediatr

women in preterm labor. Acta Obstet Gynecol Scand 82:120-128, Perinat Epidemiol 9:281-295, 1995

175. Schulman ED: Preterm delivery among women in the South Carolina 196. Helmig BR, Romero R, Espinoza J, et al: Neutrophil elastase and Medicaid High Risk Channeling Project. J Health Care Poor Under-

secretory leukocyte protease inhibitor in prelabor rupture of mem- served 6:352-367, 1995

branes, parturition and intra-amniotic infection. J Matern Fetal Neo- 176. Savitz DA, Dole N, Herring AH, et al: Should spontaneous and med-

natal Med 12:237-246, 2002

ically indicated preterm births be separated for studying aetiology? 197. Edwards RK, Clark P, Locksmith GJ, et al: Performance characteristics Paediatr Perinat Epidemiol 19:97-105, 2005

of putative tests for subclinical chorioamnionitis. Infect Dis Obstet 177. Merlino A, Laffineuse L, Collin M, et al: Impact of weight loss between

Gynecol 9:209-214, 2001

pregnancies on recurrent preterm birth. Am J Obstet Gynecol 195: 198. Yoon BH, Chang JW, Romero R: Isolation of Ureaplasma urealyticum 818-821, 2006

from the amniotic cavity and adverse outcome in preterm labor. Ob- 178. Yost NP, Owen J, Berghella V, et al: Effect of coitus on recurrent

stet Gynecol 92:77-82, 1998

preterm birth. Obstet Gynecol 107:793-797, 2006 199. Rizzo G, Capponi A, Vlachopoulou A, et al: The diagnostic value of 179. Klebanoff MA, Nugent RP, Rhoads GG: Coitus during pregnancy: is it

interleukin-8 and fetal fibronectin concentrations in cervical secre- safe? Lancet 2:914-917, 1984

tions in patients with preterm labor and intact membranes. J Perinat 180. Berghella V, Klebanoff M, McPherson C, et al: Sexual intercourse

Med 25:461-468, 1997

association with asymptomatic bacterial vaginosis and Trichomonas 200. Garry D, Figueroa R, Guero-Rosenfeld M, et al: A comparison of rapid vaginalis treatment in relationship to preterm birth. Am J Obstet Gy-

amniotic fluid markers in the prediction of microbial invasion of the necol 187:1277-1282, 2002

uterine cavity and preterm delivery. Am J Obstet Gynecol 175:1336- 181. Kurki T, Ylikorkala O: Coitus during pregnancy is not related to

bacterial vaginosis or preterm birth. Am J Obstet Gynecol 169:1130- 201. Rizzo G, Capponi A, Rinaldo D, et al: Interleukin-6 concentrations in 1134, 1993

cervical secretions identify microbial invasion of the amniotic cavity in 182. Read JS, Klebanoff MA: Sexual intercourse during pregnancy and

patients with preterm labor and intact membranes. Am J Obstet Gy- preterm delivery: effects of vaginal microorganisms. The Vaginal In-

necol 175:812-817, 1996

fections and Prematurity Study Group. Am J Obstet Gynecol 168:514- 202. Mazor M, Hershkovitz R, Ghezzi F, et al: Intraamniotic infection in 519, 1993

patients with preterm labor and twin pregnancies. Acta Obstet Gy- 183. Brustman LE, Raptoulis M, Langer O, et al: Changes in the pattern of

necol Scand 75:624-627, 1996

uterine contractility in relationship to coitus during pregnancies at 203. Mazor M, Furman B, Wiznitzer A, et al: Maternal and perinatal out- low and high risk for preterm labor. Obstet Gynecol 73:166-168,

come of patients with preterm labor and meconium-stained amniotic 1989

fluid. Obstet Gynecol 86:830-833, 1995 184. Wagner NN, Butler JC, Sanders JP: Prematurity and orgasmic coitus

204. Baumann P, Romero R, Berry S, et al: Evidence of participation of the during pregnancy: data on a small sample. Fertil Steril 27:911-915,

soluble tumor necrosis factor receptor I in the host response to intra- 1976

uterine infection in preterm labor. Am J Reprod Immunol 30:184- 193, 1993

185. Meis PJ, Goldenberg RL, Mercer BM, et al: The preterm prediction 205. Maymon E, Romero R, Pacora P, et al: A role for the 72 kDa gelatinase study: risk factors for indicated preterm births. Maternal-Fetal Medi-

(MMP-2) and its inhibitor (TIMP-2) in human parturition, premature cine Units Network of the National Institute of Child Health and

rupture of membranes and intraamniotic infection. J Perinat Med Human Development. Am J Obstet Gynecol 178:562-567, 1998

29:308-316, 2001

186. Ananth CV, Vintzileos AM: Maternal-fetal conditions necessitating a 206. Jacobsson B, Mattsby-Baltzer I, Andersch B, et al: Microbial invasion medical intervention resulting in preterm birth. Am J Obstet Gynecol

and cytokine response in amniotic fluid in a Swedish population of 195:1557-1563, 2006

women with preterm prelabor rupture of membranes. Acta Obstet 187. Meis PJ, Goldenberg RL, Mercer B, et al: The preterm prediction

Gynecol Scand 82:423-431, 2003

study: significance of vaginal infections. National Institute of Child 207. Park KH, Chaiworapongsa T, Kim YM, et al: Matrix metalloproteinase Health and Human Development Maternal-Fetal Medicine Units Net-

3 in parturition, premature rupture of the membranes, and microbial work. Am J Obstet Gynecol 173:1231-1235, 1995

invasion of the amniotic cavity. J Perinat Med 31:12-22, 2003 188. Romero R, Mazor M, Wu YK, et al: Infection in the pathogenesis of

208. Romero R, Yoon BH, Mazor M, et al: A comparative study of the preterm labor. Semin Perinatol 12:262-279, 1988

diagnostic performance of amniotic fluid glucose, white blood cell 189. Romero R, Sirtori M, Oyarzun E, et al: Infection and labor. V. Preva-

count, interleukin-6, and gram stain in the detection of microbial lence, microbiology, and clinical significance of intraamniotic infec-

invasion in patients with preterm premature rupture of membranes. tion in women with preterm labor and intact membranes. Am J Obstet

Am J Obstet Gynecol 169:839-851, 1993 Gynecol 161:817-824, 1989

209. Romero R, Quintero R, Oyarzun E, et al: Intraamniotic infection and 190. Romero R, Sepulveda W, Baumann P, et al: The preterm labor syn-

the onset of labor in preterm premature rupture of the membranes. drome: Biochemical, cytologic, immunologic, pathologic, microbio-

Am J Obstet Gynecol 159:661-666, 1988 logic, and clinical evidence that preterm labor is a heterogeneous

210. Romero R, Ghidini A, Mazor M, et al: Microbial invasion of the am- disease. Am J Obstet Gynecol 288, 1993

niotic cavity in premature rupture of membranes. Clin Obstet Gy- 191. Romero R, Yoon BH, Mazor M, et al: The diagnostic and prognostic

necol 34:769-778, 1991

value of amniotic fluid white blood cell count, glucose, interleukin-6, 211. Romero R, Baumann P, Gomez R, et al: The relationship between and gram stain in patients with preterm labor and intact membranes.

spontaneous rupture of membranes, labor, and microbial invasion of Am J Obstet Gynecol 169:805-816, 1993

the amniotic cavity and amniotic fluid concentrations of prostaglan- 192. Romero R, Mazor M, Munoz H, et al: The preterm labor syndrome.

dins and thromboxane B2 in term pregnancy. Am J Obstet Gynecol Ann N Y Acad Sci 734:414-429, 1994

168:1654-1664, 1993

193. Gomez R, Romero R, Nien JK, et al: Idiopathic vaginal bleeding during 212. Kim YM, Chaiworapongsa T, Gomez R, et al: Failure of physiologic pregnancy as the only clinical manifestation of intrauterine infection.

transformation of the spiral arteries in the placental bed in preterm J Matern Fetal Neonatal Med 18:31-37, 2005

premature rupture of membranes. Am J Obstet Gynecol 187:1137- 194. Espinoza J, Goncalves LF, Romero R, et al: The prevalence and clinical