Erna Mirani1 , Achmad Zulfa Juniarto2 , Ani Margawati2 , Sultana MH Faradz

46

Vol. 2, No. 1, Januari - Juni 2010

Pengaruh Konseling Genetik pada Tingkat Depresi terhadap
Penentuan Gender Ambigus Genitalia
Effect of Genetic Counseling on Depression Level in Rearing the Gender
of Ambiguous Genitalia
Erna Mirani1*, Achmad Zulfa Juniarto2, Ani Margawati2, Sultana MH Faradz2
ABSTRACT
Background: Ambiguous genitalia is a phrase used to describe a person whose sex chromosomes, genitalia,
and/or secondary sex characteristics which be determined as exclusively male or female. In general, it is
estimated that the risk to catch this disease is 1: 2000. Parents take an important role in making decision
for children with ambiguous genitalia concerning their gender identity and sex rearing, therefore it may
cause parents trap in depression. This research aimed to study the effect of genetics counseling session
towards parents depression level in rearing the gender of ambiguous genitalia. This research was an analytic
study with prospective approach and applying pre-post test group design.
Design and method: Data was analyzed descriptively by cross tabulation table, and analytically by T- test
with SPSS for window version 15.00.
Result: Of the 20 subjects collected in this research, seven patients with female gender were consisted of 4
(57%) with karyotipe 46,XX and 3 (42%) with 46,XY. While from 13 patients with male gender, 10 (76%) has

46,XY; 2 (15%) has mosaic 45,X/46,XY; and 1 (7%) has 46,XX. Hamilton depression scale which performed in
pre test showed 10 (50%) respondents were in mild level, 7 (35%) were moderate, and 3 (15%) were severe.
Meanwhile, the post test showed 7 (35%) respondents were having no depression, 13 (65%) were in mild
level. T- test showed that there was a significant difference between pre and post test regarding depression
level after genetic counseling session with p

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