Directory UMM :Data Elmu:jurnal:S:Small Ruminant Research:Vol38.Issue3.Nov2000:
Small Ruminant Research 38 (2000) 217±228
Physiologic and biochemical effects of subarachnoidally
administered xylazine and medetomidine in goats
P. Kinjavdekar*, G.R. Singh Amarpal, H.P. Aithal, A.M. Pawde
Division of Surgery, Indian Veterinary Research Institute, Izatnagar 243 122 (UP), India
Received 10 March 1999; accepted 18 April 2000
Abstract
Clinicophysiological, haematological and biochemical effects of xylazine (0.05 mg kgÿ1) and medetomidine
(0.01 mg kgÿ1) were studied in nine adult goats after lumbosacral subarachnoid administration. The onset of analgesia by
xylazine and medetomidine was observed in 9.111.07 and 8.662.37 min (meanS.E.), respectively. Both a2-agonists
produced moderate analgesia of hind quarter, perineum and ¯ank, mild ataxia and sedation. The duration of analgesia after
xylazine administration was 134.448.87 min and that after medetomidine was 158.339.96 min (meanS.E.). Xylazine and
medetomidine induced signi®cant (p
Physiologic and biochemical effects of subarachnoidally
administered xylazine and medetomidine in goats
P. Kinjavdekar*, G.R. Singh Amarpal, H.P. Aithal, A.M. Pawde
Division of Surgery, Indian Veterinary Research Institute, Izatnagar 243 122 (UP), India
Received 10 March 1999; accepted 18 April 2000
Abstract
Clinicophysiological, haematological and biochemical effects of xylazine (0.05 mg kgÿ1) and medetomidine
(0.01 mg kgÿ1) were studied in nine adult goats after lumbosacral subarachnoid administration. The onset of analgesia by
xylazine and medetomidine was observed in 9.111.07 and 8.662.37 min (meanS.E.), respectively. Both a2-agonists
produced moderate analgesia of hind quarter, perineum and ¯ank, mild ataxia and sedation. The duration of analgesia after
xylazine administration was 134.448.87 min and that after medetomidine was 158.339.96 min (meanS.E.). Xylazine and
medetomidine induced signi®cant (p