Faktor Risiko Yang Mempengaruhi Kejadian Acne Vulgaris Pada Siswa I Di 3 Sma Kecamatan Medan Baru, Medan

63

DAFTAR PUSTAKA

Abulnaja, K.O., 2009. Changes in the Hormone and Lipid Profile of Obese
Adolescent Saudi Females with Acne Vulgaris. Brazilian Journal of
Medical and Biological Research, 42 (6): 501-505.
Adégbidi, H., Koudoukpo, C., Atadokpèdé, F., Ango-Padonou, F., dan Yédomon,
H.G., 2014. Epidemiological and Clinical Aspects of Acne in the
Dermatology Department of the Teaching Hospital Parakou (Benin).
Journal of Cosmetics, Dermatological Sciences and Applications, 4: 129134.

Aksu, A.E.K., et al. 2012. Acne: Prevalence and Relationship with Dietary Habits
in Eskisehir, Turkey. JEADV, 26: 1503-1509.

Al-Kubaisy,

W.,

Abdullah,


N.N.,

Kahn,

S.M.,

and

Zia,

M.,

2014.

Sociodemographic Characteristics of Acne among University Students in
Damascus, Syria. Epidemiology Research International.
American

Academy


of

Dermatology,

2014.

Acne.

Available

from:

http://www.aad.org/media-resources/stats-and-facts/conditions/acne.
[Accessed May 12, 2014].
Anggrenni, O., 2014. Studi Retrospektif Pasien Akne Vulgaris di RSUP H. Adam
Malik Medan Periode Tahun 2010-2012. Tesis Program Magister
Kedokteran Klinik Departemen Ilmu Kesehatan Kulit dan Kelamin Fakultas
Kedokteran Universitas Sumatera Utara.

Universitas Sumatera Utara


64

Arshdeep, D.D., 2013. What’s New in the Management of Acne?. Indian J
Dermatol Venereol Leprol, 79: 279-87.
Axelsson, J., Ingre, M., Åkerstedt, T., and Holmbäck, U., 2005. Effects of Acutely
Displaced Sleep on Testosterone. J Clin Endocrinol Metab, 90: 4530–4535.
Bagatin et al., 2014. Acne Vulgaris: Prevalence and Clinical Forms in
Adolescents from São Paulo, Brazil. An Bras Dermatol 89(3): 428-35
Behrman, R.E., Kliegman, R.M., and Jenson, H.B., 2003. Nelson Textbook of
Pediatrics. 17th ed. Elsevier.
Bhambri, S., Del Rosso, J.Q., and Bhambri, A., 2009. Pathogenesis of Acne
Vulgaris : Recent Advances. Journal of Drugs in Dermatology.
Bhate, K. and Williams, H.C., 2013. Epidemiology of Acne Vulgaris. Br J
Dermatol, 168 (3): 474-85.
Bogino, E.A., Kebede, M.G., and Kahsay, A.B., 2014. Acne at Ayder Referral
Hospital among Patients Attending Dermatologic Clinic, Mekelle, Northern
Ethiopia, September 2014. Science Journal of Clinical Medicine, 3(6): 129134.
Böhm, M., et al., 2002. Evidence for Expression of Melanocortin-1 Receptor in
Human Sebocytes In Vitro and In Situ. J Invest Dermatol, 118: 533-539.

Bowe, P.W., Joshi, S.S., and Shalita A.R., 2010. Diet and Acne. J Am Acad
Dermatol.

Universitas Sumatera Utara

65

Caperton C et al., 2014. Double-Blind, Placebo-Controlled Study Assessing the
Effect of Chocolate Consumption in Subjects with a History of Acne
Vulgaris. J Clin Aesthet Dermatol, 7(5): 19-23.
Capitanio, B., Sinagra, J.L., Ottaviani, M., Bordignon, V., Amantea, A., and
Picardo, M., 2009. Acne and Smoking. Dermato-Endocrinology, 1 (3): 129135.
Carolyn, I.J., Jeffrey, S.D., and Michael, S.K., 2001. Acne Scarring: A
Classification System and Review of Treatment Options. Journal of the
American Academy of Dermatology, 45 (1): 109–117.
Colrain, I.M. and Baker, F.C., 2011. Changes in Sleep as a Function of
Adolescent Development. Neuropsychol Rev, 21: 5–21.
Costa, A., Moisés, T.A., and Lage, D., 2010. Acne and Diet: Truth or Myth?. An
Bras Dermatol, 85 (3): 346-53.
Dahlan, M.S. 2012. Analisis Multivariat Regresi Logistik, Seri 9. Jakarta:

Epidemiologi Indonesia.
Dahlan, M.S. 2014. Statistik untuk Kedokteran dan Kesehatan; Deskriptif,
Bivariat, dan Multivariat Dilengkapi Aplikasi Menggunakan SPSS. Jakarta:
Epidemiologi Indonesia.
Dahlan M.S. 2009. Penelitian Diagnostik; Dasar-Dasar Teoretis dan Aplikasi
dengan Program SPSS dan Stata. Jakarta: Salemba Medika.
Dawson, A.L. and Dellavalle, R.P., 2013. Acne vulgaris. BMJ, 346.

Universitas Sumatera Utara

66

Del Rosso, J.Q., 2007. Study Results of Benzoyl Peroxide 5% Clindamycin 1%
Topical Gel, Adapalene 0,1%, and Use in Combination for Acne Vulgaris. J
drugs dermatol, 6 (6): 616-622.
Dhamayanti, M., 2013. Overview Adolescent Health Problems and Services.
Jakarta : IDAI. Available from: http://idai.or.id/public-articles/seputarkesehatan-anak/overview-adolescent-health-problems-and-services.html.
[Accessed April 17, 2014].
Do, J.E., Cho, S., In, S., Lim, K., Lee, S., and Lee, E, 2009. Psychosocial Aspects
of Acne Vulgaris: A Community-based Study with Korean Adolescents.

Ann Dermatol, 21 (2): 125-129.
Dougan P dan Rafikhah N., 2014. Dark and White Chocolate Consumption and
Acne Vulgaris: A Case-Control Study. Asian J Clin Nutr, 6(2): 35-40.
Downie, M.M.T., Sanders, D.A., and Kelaey, T., 2002. Modelling the remission
of individual acne lesions in vitro. British Journal of Dermatology, 147:
869–878.
Dreno, B. and Poli, F., 2003. Epidemiology of Acne. Dermatology, 206(1): 7-10.
Eichenfield, L.F. et al., 2013. Evidence-Based Recommendations for the
Diagnosis and Treatment of Pediatric Acne. Pediatrics : Official Journal of
the American Academy of Pediatrics, 131: S163–S186.
Ewadh, M.J., Shemran, K.A., and Al-Hamdany, K.J., 2011. The Correlation of
Some Hormones with Acne Vulgaris. International Journal of Science and
Nature, 2(4): 713-717.

Universitas Sumatera Utara

67

Fabbrocini, G., et al., 2010 Acne Scars: Pathogenesis, Classification and
Treatment. Dermatology Research and Practice.

Ferdowsian, H.R. and Levin, S., 2010. Does Diet Really Affect Acne?. Skin
Therapy Letter, 15(3): 1-2.
Freedberg, I.M., Tomic-Canic, M., Komine, M., and Blumenberg, M., 2001.
Keratins and the Keratinocyte Activation Cycle. J Invest Dermatol, 116:
633-640.
Ganceviciene, R., Graziene, V., Böhm, M, and Zouboulis, C.C., 2007. Increased
In Situ Expression of Melanocortin-1 Receptor in Sebaceous Glands of
Lesional Skin of Patients with Acne Vulgaris. Experimental Dermatology,
16: 547-552.
Ghodsi, S.Z., Orawa, H., and Zouboulis, C.C., 2009. Prevalence, Severity, and
Severity Risk Factors of Acne in High School Pupils: A Community-Based
Study. Journal of Investigative Dermatology, 129: 2136-2141.
Granner, D.K., 2006. Keragaman Sistem Endokrin. In: Murray, R.K., Granner,
D.K., dan Rodwell, V.W. 27th ed. Biokimia Harper. Jakarta : EGC, 455-477.
Guy, R., Green, M.R., and Kealey, T., 1996. Modeling Acne In Vitro. J Invest
Dermatol, 106: 176–182.
Halvorsen, J.A., Dalgard, F., Thoresen, M., Bjertness, E., dan Lien, L., 2009. Is
the Association Between Acne and Mental Distress Influenced by Diet?
Results from a Cross-Sectional Population Study among 3775 Late
Adolescents in Oslo, Norway. BioMed Central Public Health, 9 (340).


Universitas Sumatera Utara

68

Handelman, G.J., Packer, L., Cross, C.E., 1996. Destruction of Tocopherols,
Carotenoids, and Retinol in Human Plasma by Cigarette Smoke. Am J Clin
Nutr, 63: 559-65.
Hanisah, A., Omar, K., and Shah, S.A., 2009. Prevalence of Acne and its Impact
on the Quality of Life in School-Aged Adolescents in Malaysia. J Primary
Health Care, 1 (1): 20–25
Harahap, M., 1998. Ilmu Penyakit Kulit. Jakarta : Hipokrates, 35-45.
Harrison, W.J., Bull, J.J., Seltman, H., Zouboulis, C.C., and Philpott, M.P., 2007.
Expression of Lipogenic Factors Galectin-12, Resistin, SREBP-1, and SCD
in Human Sebaceous Glands and Cultured Sebocytes.

Journal of

Investigative Dermatology, 127: 1309–1317.
Hughes, B.R., Morris, C., Cunliffe, W.J., and Leigh, I.M., 1996. Keratin

Expression in Pilosebaceous Epithelia in Truncal Skin of Acne Patiens.
British Journal of Dermatology, 134: 247-256.
Huynh, M., Gupta, R., and Koo, J.Y.M., 2013. Emotional Stress as A Trigger for
Inflammatory Skin Disorders. Semin Cutan Med Surg, 32:68-72.
Ingham E.E., Eady, A., Goodwin C.E., Cove J.H., and Cunliffe W.J., 1992. ProInflammatory Levels of Interleukin-1α-like Bioactivity are Present in the
Majority of Open Comedones in Acne Vulgaris. J Invest Dermatol, 98:
895–901.
Isard, O., et al., 2011. Propionibacterium acnes Activates the IGF-1/IGF-1R
System in the Epidermis and Induces Keratinocyte Proliferation. Journal of
Investigative Dermatology, 131: 59-66.

Universitas Sumatera Utara

69

Ismail, N.H., Manaf, Z.A., and Azizan, N.Z., 2012. High Glycemic Load Diet,
Milk, and Ice Cream Consumption are Related to Acne Vulgaris in
Malaysian Young Adults: A Case Control Study. BMC Dermatology,
12(13).
J.McWilliam, 2009. Acne Vulgaris : Clinical Features, Assessment and

Treatment. Nursing Standard, 23(34): 49-56.
Jarrousse, V., Castex-Rizzi, N., Khammari, A., Charveron, M., and Dréno, B.,
2007.

Modulation

of

Integrins

and

Filaggrin

Expression

by

Propionibacterium Acnes Extracts on Keratinocytes. Arch Dermatol Res,
299:441–447.

Khani, S. and Tayek, J.A., 2001. Cortisol Increases Gluconeogenesis in Humans:
its Role in the Metabolic Syndrome. Clinical Science, 101: 739–747.
Khunger N and Kumar C., 2012. A Clinico-Epidemiological Study of Adult Acne:
Is It Different from Adolescent Acne?. Indian J Dermatol Venereol Leprol,
78(3): 335-41.
Klaz, I., Kochba, I., Shohat, T., Zarka, S., and Brenner, S., 2006. Severe Acne
Vulgaris and Tobacco Smoking in Young Men. Journal of Investigative
Dermatology, 126: 1749-1752.
Knutsen-Larson, S., Dawson, A.L., Dunnick, C.A., and Dellavalle, R.P., 2012.
Acne Vulgaris: Pathogenesis, Treatment, and Needs Assessment. Dermatol
Clin, 30: 99–106.
Kraft, J. and Freiman, A. 2011. Management of Acne. CMAJ, 183(7): E430-E435.

Universitas Sumatera Utara

70

Kuiri-Hänninen, T., Haanpää, M., Turpeinen, U., Hämäläinen, E., Dunkel, L., dan
Sankilampi, U., 2013. Transient Postnatal Secretion of Androgen Hormones
is Associated with Acne and Sebaceous Gland Hypertrophy in Early
Infancy. J Clin Endocrinol Metab, 98(1): 199-206.
Kurokawa, I. et al., 2009. New Developments in Our Understanding of Acne
Pathogenesis and Treatment. Experimental Dermatology, 18: 821–832.
Kursunluoglu, L., et al., 2009. Insulin-like Growth factor-I and Insulin –like
Growth Factor Binding Protein-3 Polymorphism in Patients with Thyroid
Dysfunction. Archives of Medical Research, 40: 42-47.
Kurzen, H., et al., 2004. Phenotypical and Molecular Profiling of the
Extraneuronal Cholinergic System of the Skin. J Invest Dermatol, 123: 937
–949.
Leproult, R. and Van Cauter, E., 2011. Effect of 1 Week of Sleep Restriction on
Testosterone Levels in Young Healthy Men. JAMA, 305: 2173–2174.
Li, Z., Wen-Hwa, L., Anthonavage, M., and Eisinger, M., 2006. Melanocortin-5
Receptor: A Marker of Human Sebocyte Differentiation. Peptides, 27: 413420.
Lomri, A., Lemonnier, J., Delannoy, P., and Marrie, P.J., 2001. Increased
Expression of Protein Kinase Ca, Interleukin-1a, and RhoA Guanosine 59Triphosphatase in Osteoblasts Expressing the Ser252Trp Fibroblast Growth
Factor 2 Apert Mutation: Identification by Analysis of Complementary
DNA Microarray. J Bone Miner Res, (16): 705–712.
Magin, P., Pond, D., Smith, W., and Watson, A., 2005. A Systematic Review of
the Evidence for ‘Myths and Misconceptions’ in Acne Management: Diet,
Face-Washing and Sunlight. Family Practice, 22: 62-70.

Universitas Sumatera Utara

71

Mancini, A.J., 2008. Incidence, Prevalence, and Patophysiology of Acne. Johns
Hopkins Advanced Studies in Medicine, 8 (4): 100-105.
Mannocci, A., et al., 2012. Association between Smoking Habits and Acne
Vulgaris, A Case Control Study. IJPH, 9 (3).
Mannocci, A., Semyonov, L., Saulle, R., and Boccia, A., 2010. Evaluation of the
Association between Acne and Smoking: Systematic Reviewand MetaAnalysis of Cross-Sectional Studies. IJPH, 7 (3): 256-261.
Mantzoros, C.S., 2011. Leptin in Human Physiology and Pathophysiology. Am J
Physiol Endocrinol Metab, 301: E567–E584.
Mcdowell, A., et al., 2005. Propionibacterium Acnes Types I and II Represent
Phylogenetically Distinct Groups. J. Clin. Microbiol, 43(1): 326-334.
Melnik, B. and Schmitz, G., 2008. FGFR2 Signalling and the Pathogenesis of
Acne. JDDG, 9 (6): 721–728.
Movita, T., 2013. Acne Vulgaris. CDK-203, 40(4): 269-272.
Mukhtar, Z., Haryuna, T.S.H., Effendy, E., Betty, dan Zahara, D., Desain Klinis
dan Statistika Kedokteran. Medan: USU Press.
Munawar, S., Afzal, M., Aftab, M., Rizvi, F., and Chaudry, M.A., 2009.
Precipitating Factors of Acne Vulgaris in Females. Ann. Pak. Inst. Med.
Sci., 5(2): 104-107.
Netea, S.A., et al., 2013. Chocolate Consumption Modulates Cytokine Production
in Healthy Individuals. Cytokine, 62: 40-43.

Universitas Sumatera Utara

72

Nguyen, T.T., 2013. Acne Treatment: Easy Ways to Improve Your Care. The
Journal of Family Practice, 62 (2): 82-89.
Noorbala, M.T., Mozaffary, B., and Noorbala, M., 2013. Prevalence of Acne and
its Impact on the Quality of Life in High School-Aged Adolescents in Yazd,
Iran. Journal of Pakistan Association of Dermatologists, 23(2): 168-172.
Novak, P.D., 1998. Kamus Saku Kedokteran Dorland. Jakarta: EGC.
Ottaviani, M., Alestas, T., Flori, E., Mastrofrancesco, A., Zouboulis, C.C., and
Picardo, M., 2006. Peroxidated Squalene Induces the Production of
Inflammatory Mediators in HaCaT Keratinocytes: A Possible Role in Acne
Vulgaris. Journal of Investigative Dermatology, 126: 2430–2437.
Passi, S., De Pità, O., Puddu, P., and Littarru, G.P., 2002. Lipophilic Antioxidant
in Human Sebum and Aging. Free Radic Re, 36: 471-477.
Pavlovsky, L. and Friedman, A., 2007. Pathogenesis of Stress –Associated Skin
Disorders: Exploring the Brain-Skin Axis. Curr Probl Dermatol, 35: 136145.
Philips, N., Auler, S., Hugo, R., and Gonzalez, S., 2011. Beneficial Regulation of
Matrix Metalloproteinases for Skin Health. Enzyme Res.
Pindha, I.S., 2004. Akne Vulgaris. In: Soetjiningsih. 2004. Buku Ajar Tumbuh
Kembang Remaja dan Permasalahannya. Jakarta : Sagung Seto, 107-117.
Poli, F., 2007. Acne on Pigmented Skin. Int J dermatol, 46 (1): 39-41.

Universitas Sumatera Utara

73

Portugal, M., Barak, V., Ginsburg, I., and Kohen, R., 2007. Interplay Among
Oxidants, Antioxidants, and Cytokines in Skin Disorders: Present Status and
Future Considerations Biomedicine & Pharmacotherapy, 61: 412-422.
Ray, C., Trivedi, P., dan Sharma, V., 2013. Acne and its Treatment Lines.
International Journal of Research in Pharmaceutical and Biosciences, 3
(1): 1-16.
Raza, K., Talwar, V., Setia, A., and Katare, O.P., 2012. Acne: An Understanding
of the Disease and its Impact on Life. Int. J. Drug Dev. & Res., 4 (2): 14-20.
Reynolds, A.C., et al., 2012. Impact of Five Nights of Sleep Restriction on
Glucose Metabolism, Leptin and Testosterone in Young Adult Men. PLoS
ONE, 7(7).
Rizvi et al., 2010. Pre-Examination Stress in Second Year Medical Students in A
Government College. J Ayub Coll Abbottabad, 22(2): 152-155.
Rohr, U.D., 2002. The Impact of Testosterone Imbalance on Depression and
Women’s Health. Maturitas, 41 (1): S25-S46.
Sahib, A.S., Al-Anbari, H.H., and Abu Raghif, A.R., 2013. Oxidative Stress in
Acne Vulgaris: An Important Therapeutic Target. J Mol Pathophysiol, 2:
27-31.
Sarici, G., Cinar, S., Armutcu, F., Altinyazar, C., Koca, R., and Tekin, N.S., 2010.
Oxidative Stress in Acne Vulgaris. JEADV, 24: 763-767.
Sastroasmoro, S. and Ismael, S., 2011. Dasar-Dasar Metodologi Penelitian
Klinis. Jakarta: Sagung Seto.

Universitas Sumatera Utara

74

Savage, L.J. and Layton, A.M., 2010. Treating Acne Vulgaris: Systemic, Local,
and Combination Therapy. Expert Rev Clin Pharmacol, 13(4): 563-580.
Schmid S.M., Hallschmid, M., Jauch-Chara, K., Lehnert, H., and Schultes, B.,
2012. Sleep Timing may Modulate the Effect of Sleep Loss on Testosterone.
Clin Endocrinol, 77: 749–754.
Schröder, J.M. and Harder, J., 2006. Antimicrobial Skin Peptides and Proteins.
Cell. Mol. Life Sci, 63: 469–486.
Setiawan, E., 2014. Kamus Besar Bahasa Indonesia. Jakarta: Badan
Pengembangan dan Pembinaan Bahasa, Kemdikbud (Pusat Bahasa).
Available from: http://kbbi.web.id/jerawat. [Accessed May 28, 2014].
Shaheen, B. and Gonzalez, M., 2013. Acne Sans P.acnes. Journal of the European
Academy of Dermatology and Venereology, 27: 1–10.
Shen, Y., et al. 2012. Prevalence of Acne Vulgaris in Chinese Adolescents and
Adults: A Community-based Study of 17.345 Subjects in Six Cities. Acta
Derm Venereol, 92: 40-44.
Smith, R.N., Braue, A., Varigos, G.A., and Mann, N.J., 2008. The Effect of a Low
Glycemic Load Diet on Acne Vulgaris and the Fatty Acid Composition of
Skin Surface Tryglycerides. J Dermatol Sci, 50(1): 41-52.
Smith, T.M., Gilliland, K., Clawson, G.A., and Thiboutot, D., 2008. IGF-1
Induces SREBP-1 Expression and Lipogenesis in SEB-1 Sebocytes via
Activation of the Phosphoinositide 3-Kinase (PI3-K)/Akt Pathway. J Invest
Dermatol, 128 (5): 1286–1293.

Universitas Sumatera Utara

75

Soldin, O.P., Makambi, K.H., Soldin, S.J., dan O’Mara, D.M., 2011. Steroid
Hormone Levels Associated with Passive and Active Smoking. Setroids, 76
(7): 653-659.
Stawiski, M.A., 2003. Akne dan Keadaan Terkait. In: Price, S.A., 6th ed.
Patofisiologi : Konsep Klinis Proses-Proses Penyakit. Jakarta : EGC, 14229.
Stevens, M.S. and Benbadis, S.R., 2013. Normal Sleep, Sleep Physiology, and
Sleep

Deprivation.

Available

from

http://emedicine.medscape.com/article/1188226-overview#a30.

:
[Accessed

May 29, 2014].
Stewart, M.E., Downing, D.T., Cook, J.S., Hansen J.R., dan Strauss, J.S., 1992.
Sebaceous Gland Activity and Serum Dehydroepiandrosterone Sulfate
Levels in Boys and Girls. Arch Dermatol, 128(10): 1345-1348.
Strauss, J.S., et al., 2007. Guidelines of care for acne vulgaris management. J Am
Acad Dermatol, 56: 651-63.
Tasli, L., et al., 2013. Insulin-Like Growth Factor-I Gene Polymorphism in Acne
Vulgaris. Journal of the European Academy of Dermatology and
Venereology, 27: 254-257.
Thiboutot, D. and WenChieh, C., 2003. Update and Future of Hormonal Therapy
in Acne. Dermatology, 206 (1): 57-67.
Thiboutot, D., Harris, G., Iles, V., Cimis, G., Gilliand, K., and Hagari, S., 1995.
Activ tiy of the Typ e 1 5 α-Reductase Exhibits Regional Differences in
Isolated Sebaceous Glands and Whole Skin. J Invest Dermatol, 105: 209214.

Universitas Sumatera Utara

76

Thiboutot, D.M., Knaggs, H., Gilliland, K., and Hagari, S., 1997. Activity of Type
1 5α-Reductase is greater In the Follicular Infrainfundibulum Compared
with the Epidermis. British Journal of Dermatology, 136: 166-171.
Thielitz, A. and Gollnick, H., 2013. Recent Therapeutic Developments for Acne:
Advances

in

the

Pathophysiology

of

Acne.

Available

from:

http://www.medscape.org/viewarticle/778129_2. [Accessed May 10, 2014].
Titus, S. and Hodge, J., 2012. Diagnosis and Treatment of Acne. Am Fam
Physician, 86(8): 734-740.
Tjekyan, R.M.S., 2008. Kejadian dan Faktor Risiko Akne Vulgaris. Media
Medika Indonesiana, 43(1): 37-43.
Toyoda, M. and Morohashi, M., 2003. New Aspects in Acne Inflammation.
Dermatology 2003, 206:17-23.
Trisnawati, S.K. and Setyorogo, S., 2013. Faktor Risiko Kejadian Diabetes
Melitus Tipe II Di Puskesmas Kecamatan Cengkareng Jakarta Barat Tahun
2012. Jurnal Ilmiah Kesehatan, 5(1): 6-11.
Tsoy, N. 2013. The Influence of Dietary Habits on Acne. World J Med Sci., 8(3):
212-216.
Wahyuni,

A.S.,

2007.

Statistika

Kedokteran.

Jakarta:

Bamboedoea

Communication.
Wasitaatmadja, S.M., 2010. Akne, Erupsi Akneiformis, Rosasea, Rinofima. In:
Djuanda, A., Hamzah, M. & Aisah, S., 6th ed. Ilmu Penyakit Kulit dan
Kelamin. Jakarta : FKUI, 253-260.

Universitas Sumatera Utara

77

Williams, H.C., Dellavale R.P., and Garner, S., 2011. Acne Vulgaris. Lancet, 379:
361-72.
Witte, E., Witte, K., Warszawska, K., Sabat, R., Wolk, K., 2010. Interleukin-22:
A Cytokine Produced by T, NK and NKT Cell Subsets, with Importance in
the Innate Immune Defense and Tissue Protection. Cytokine Growth Factor
Rev, 21: 365–379.
Wittert, G., 2014. The Relationship between Sleep Disorders and Testosterone in
Men. Asian Journal of Andrology, 16: 262–265.
Wyrzykowska, N., Wyrzykowski, M., Żaba. R.W., Silny, W., dan Grzymisławski,
M., 2013. Diet and Acne Vulgaris. Przegląd Gastroenterologiczny, 8 (2):
93–97.
Yaykasli, K.O., Turan, H., Kaya, E., and Hatipoglu, O.F., 2013. Polymorphisms
in the Promoters of MMP-2 and TIMP-2 Genes in Patients with Acne
Vulgaris. Int J Clin Exp Med, 6 (10): 967-972.
Youn S.W., Park, E.S., Lee, H.D., Huh, C.H., and Park, K.C., 2005. Does Facial
Sebum Excretion Really Affect the Development of Acne?. The British
Journal

of

Dermatology.

Available

from:

http://www.medscape.com/viewarticle/515685_2 [Accessed June 6, 2014].
Ziegler, C.G., Krug, A.W., Zouboulis, C.C., and Bornstein, S.R., 2007.
Corticotropin Releasing Hormone and its Function in the Skin. Horm Metab
Res, 39: 106 – 109.

Universitas Sumatera Utara

78

Zouboulis, C.C., et al., 2002. Corticotropin-Releasing Hormone: An Autocrine
Hormone that Promotes Lipogenesis in Human Sebocytes. PNAS, 99 (10):
7148–7153.
Zouboulis, C.C., 2003. Sebaceous Gland in Human Skin - the Fantastic Future of
a Skin Appendage. J Invest Dermatol, 120: xiv-xv.
Zouboulis, C.C., 2009. Zileuton, A New Efficient and Safe Systemic Anti-Acne
Drug. Dermato-Endocrinology, 1(3): 188-192.
Zouboulis, C.C., Seltmann, H., and Alestas, T., 2010. Zileuton Prevents the
Activation of the Leukotriene Pathway and Reduces Sebaceous Lipogenesis.
Dermatology, 19: 148–150.

Universitas Sumatera Utara