Evaluasi Penggunaan Antibiotika Secara Kualitatif dan Kuantitatif Pada Pasien High Care Unit di Rumah Sakit Umum Pusat Haji Adam Malik Medan Periode Februari – April 2016

Lampiran 1. Data Pasien
RUANG
HCU

KODE
PASIEN

NAMA
PASIEN

No. RM

JK

USIA
(Thn)

BB
(Kg)

51

CVCU

1

MR

00.66.62.56

L

21

43

CVCU

2

MS

00.65.49.49

L

77

56

CVCU

3

TK

00.65.49.87

L

53

57

CVCU

4

NA

00.66.91.47

P

4
Bulan

6

HDU

5

MP

00.52.15.60

L

40

59

HDU

6

LH

00.66.78.13

P

73

58

SC

7

NB

00.65.88.80

P

67

54

SC

8

RT

00.66.76.44

L

50

56

SC

9

SIN

00.66.81.67

P

57

53

CVCU

10

RNG

00.64.25.65

L

17

50

DIAGNOSA
CHF fc IV ec AR
Severe, MR
Severe, TR MOA
Severe, PR mid
PH
Acute lung
Oedem
CHF fc III ec
CAD, HHD
CHF ec ASD,
VSD, BP, Kejang
Demam, GE
Penurunan
kesadaran ec HE
grad III-IV, SH
std PC (Hepatitis)
Diffuse Injury

Apatis, Stroke
Iskemik releven,
NPH, DD,
Hipertensi,
Enselepati.
Stroke
Hemoragik
Stroke
Hemoragik
SLE, Vaskular,
CHF fc II ec
Myocarditis,
Shok Sepsis ec
Pneumonia

Spesimen

KULTUR
Bakteri
Sensitive

Resisten

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

Universitas Sumatera Utara

HDU

11

AP

00.46.58.04

P

24

50

52

CVCU

12

RS

00.66.88.02

P

52

49

CVCU

13

ST

00.14.80.49

P

70

51

CVCU

14

PR

00.66.94.37

L

62

60

CVCU

15

JSS

00.67.00.60

L

42

60

CVCU

16

CBS

00.46.76.29

P

77

55

Penurunan
kesadaran SCE,
CKD Stage V,
hipertensi stage
II, Hiponatremi

CHF
NSTEMI,
TIMI, Roc 3/7,
DM Type 2
PSMBA ec
Gastritis,
NSTEMI
Lateral
STEMI inferior
onset 11 jam
killip I TIMI
Risk 2/14,
Hipertensi
Stage II
PSMBA ec
Gastritis,
Erosiva, sepsis
ec pneumonia,
anemia,
pendaharahan

Urine
kateter

E-coli

Amikasin,
Imepenem,
Gentamisin,
Meropenem

Darah

Interococcus
Faecium

Linezolid dan
Vancomycin

Sputum

1. Klebsiella
pneumoni

Amikasin

-

2.
Acinetobacter
baumanii
-

Imepenem,
Meropenem,
Polymyxin B
-

Ampicilin, Cetriaxone,
Cefotaxime,
Levofloxacin,
Ceftazidime,ciprofloxacin
Ampicilin, Cetriaxone,
Levofloxacin,
Ceftazidime
Ampicilin, Cetriaxone,
Cefotaxime,
Levofloxacin,
Ceftazidime
Amikasin,Ampisilin,
Amoxisilin, Gentamisin,
Cetriaxone, Levofloxacin
-

-

-

-

-

-

-

-

-

-

-

-

-

Sputum

Tidak ada
pertumbuhan
bakteri

-

-

Universitas Sumatera Utara

HDU

17

NKS

00.66.55.38

P

55

60

18

NS

00.40.28.47

L

73

65

SC

19

NP

00.58.79.23

L

62

70

SC

20

JT

00.66.90.50

L

60

50

SC

21

FR

00.66.93.82

P

61

51

SC
SC

22
23

SD
MPS

00.66.93.83
00.66.95.97

L
L

67
44

60
80

CVCU

24

CP

00.67.00.66

L

71

65

CVCU

25

CC

00.45.12.10

L

69

50

CVCU

26

AS

00.67.03.96

L

65

80

SC

27

MT

00.67.04.02

P

83

50

53

HDU

Darah

Klebsiella
Pneumoni

Amikasin,
Imepenem,
Gentamisin,
Meropenem,
Levofloxacin

Sputum

Acinetobacter
baumanii

Amikasin,
Imepenem,
Meropenem

-

-

-

-

-

-

-

-

Sputum

Tidak ada
pertumbuhan
bakteri

-

-

-

-

-

-

-

Tidak ada
pertumbuhan
bakteri

-

-

-

-

-

-

-

-

-

-

-

-

-

-

Hipertensi samnolen
ec Stroke hemoregi

DM Type II, anemia,
CHF fc I ec CAD
Stroke Iskemik, CHF,
Pneumoni
Stroke Iskemik
Hemiparise, Stroke
Iskemik
Stroke Hemoragik
Stroke Hemoragik
STEMI antereoseptal
onset 2 hari killip II
UAP dd NSTEMI,
AKI dd CUP
CHF ec CAD, HHD,
Hipertensi, sepsis ec
pneumonia, PPOK,
asidosis
Penurunan kesadaran,
spontaneus, ICH (R),
stroke hemoragik

Darah

Ampicillin,
Cefotaxime,
Ceftazidime,
Ceftriaxone,
Ciprofloxacin
Ampicillin,
Cefotaxime,
Ceftazidime,
Ceftriaxone,
Ciprofloxacin

Universitas Sumatera Utara

54

SC

28

KM

00.35.64.38

L

57

70

SC

29

FN

00.65.65.96

L

34

48

HDU

30

RH

00.66.82.90

L

16

45

HDU

31

KT

00.66.80.68

P

52

58

SC

32

RP

00.67.97.20

P

66

50

SC

33

ST

00.67.11.76

P

65

55

SC

34

DS

00.67.15.44

L

47

60

CVCU

35

MS

00.67.09.52

L

51

65

SC

36

RS

00.60.36.28

P

81

65

SC

37

SR

00.67.14.71

P

48

70

SC
SC

38
39

SM
CZ

00.67.16.86
00.67.17.10

P
P

59
61

80
57

Hemiparise sinistra,
PN VII, XII, UMN
sinistra ec stroke
iskemik rekuren dan
stroke hemoragic
Stroke iskemik, CHF
susp, TB Paru
HI GCS g, EDH (L)
P, Lakso (L) F,
prekursor, penurunan
kesadaran sejak 28/02
Tumor spinal,
thoracal V
Somnolen,
hemiparise ed. Dd.
Stroke iskemik dan
stroke hemoragik
Stroke iskemik
Hemiparise sinistra,
IN VI, UMN sinistra
ec. Stroke hemoragik
UAP, CHF fc III ec
HHD, HT urgent, dan
DM type II
Hemiparise sinistra,
PN VII, XII, UMN
sinistra ec stroke
iskemik rekuren
Hemiparise ec Stroke
Hemoragik
Stroke Hemoragik
Stroke Hemoragik

-

-

-

-

-

-

-

-

Darah

Tidak ada
pertumbuhan
bakteri

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

Universitas Sumatera Utara

40

MH

00.58.37.26

L

57

60

SC

41

RG

00.66.87.86

P

62

58

SC

42

UB

00.67.19.41

L

41

60

SC

43

MS

00.67.22.46

L

58

75

HDU

44

RAS

00.67.14.45

P

20

46

CVCU

45

KM

00.66.96.86

L

59

50

CVCU

46

RS

00.67.14.35

P

51

69

CVCU

47

KR

00.67.17.06

P

41

70

CVCU

48

JN

00.67.18.29

L

40

60

CVCU

49

RK

00.67.18.89

P

78

59

CVCU

50

RKK

00.66.33.19

L

85

75

55

SC

Penurunan
kesadaran, lemah
sebelah kanan ec
stroke iskemik
Soporokoma,
hemiparise dextra
ec stroke iskemik
Somnolen,
hemiparise sinistra
ec. dd. Stroke
iskemik dan stroke
hemoragik
Wajah miring ke
kiri, Stroke
Iskemik, hipertensi,
hiperkolesterol
Epilepsi umum
SVT ventrikal,
takikardia with
pulse dengan
hemodinamik tak
stabil
TPM a/1, TAUB ec
folib PPM,
Hipertensi stage II
CHF fc IV ec HHD,
pneumonia,
hipertensi stage II
CHF fc IV ac CAD,
HHD, hipertensi
stage II, post PCI
CHF fc IV
AF RVR fc IV ec
CAD, HHD

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

Universitas Sumatera Utara

51

JS

00.67.22.01

L

41

76

SC
SC

52
53

ES
JP

00.67.27.77
00.67.29.14

L
L

57
53

65
65

SC

54

IM

00.67.30.83

L

46

73

SC
SC
CVCU
CVCU

55
56
57
58

MSS
JS
BTB
MAT

00.67.36.60
00.67.36.18
00.66.98.18
00.45.34.14

L
L
L
L

43
48
7
67

65
65
16
50

CVCU

59

MS

00.52.00.61

L

63

80

CVCU

60

IS

00.67.26.37

L

47

69

CVCU
CVCU

61
62

HA
MT

00.67.23.07
00.67.35.86

L
L

72
52

54
60

HDU

63

AR

00.67.28.02

L

60

55

CVCU

64

UM

00.67.38.16

L

67

60

56

SC

HDU

65

RP

00.66.63.68

P

78

72

Hemiparise dextra ec
stroke hemoragic
Stroke Hemoragik
Stroke iskemik
Hipertensi stage 2,
DM Type II,
Hemoragic sinistra ec
dd stroke iskemik
recurent & stroke
hemoragic
Stroke Hemoragik
Stroke Hemoragik
Cyanotic spell, TOF
UAP dd NSTEMI
CAD pro CABG,
recurent STEMI
inferior ekstensive
Recurent STEMI
inferior, DM type 2
SB Symptomatic
STEMI Anteroseptal
Penurunan kesadaran,
HI, GCS ec SDH
Gagal nafas tipe 2,
PPOK, pneumoni

CKD stage V, sepsis
ec pneumoni

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

Ciprofloxacin,
doxycycline,
levofloxacin, dan
trimetoprim

Amikasin,
ampicilin,
amoxiclav,
cefotaxime,
ceftazidime,
gentamisin,
meropenem,
piperacilin

Urine
kateter

Chryseobacterium
cyle

Universitas Sumatera Utara

Lampiran 2. Data Antibiotika
REGIMEN ANTIBIOTIKA
KP

NO

1
2
3

1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16

4
5
6
7
8

57
9
10

11

12

17
18
19
20
21

NAMA
Ceftriaxone
Ceftriaxone
Ceftriaxone
Cefotaxime
Gentamisin
Ceftriaxone
Ceftriaxone
Ciprofloxacin
Meropenem
Ceftazidime
Ceftriaxone
Ceftriaxone
Levofloxacin
Meropenem
Ceftriaxone
Ciprofloxacin
Ciprofloxacin
Meropenem
Amikasin
Ceftriaxone
Meropenem

DOSIS
1 gram / 12 jam
1 gram / 12 jam
1 gram / 12 jam
100 mg / 8 jam
7,5 mg / 12 jam
1 gram / 12 jam
1 gram / 12 jam
500 mg / 12 jam
1 gram / 8 jam
1 gram / 12 jam
1 gram / 12 jam
2 gram / 24 jam
500 mg / 24 jam
1 gram / 24 jam
2 gram / 12 jam
400 mg / 24 jam
400 mg / 12 jam
500 mg / 12 jam
1 gram / 24 jam
2 gram / 12 jam
1 gram / 8 jam

RUTE
i.v
i.v
i.v
i.v
i.v
i.v
i.v
p.o
i.v
i.v
i.v
i.v
i.v
i.v
i.v
i.v
i.v
i.v
i.v
i.v
i.v

LAMA
RAWAT
(HARI)
17
6
9
5
7
11
16
6
7
7

19

9

LAMA
PENGGUNAAN JUMLAH
(HARI)
10
20 gram
6
12 gram
9
18 gram
5
1,5 gram
5
75 mg
6
12 gram
11
22 gram
4
4 gram
1
3 gram
1
2 gram
7
14 gram
4
8 gram
4
2 gram
3
3 gram
11
44 gram
7
2,8 gram
5
4 gram
10
10 gram
4
4 gram
3
12 gram
8
24 gram

KATEGORI
GYSSENS

MASALAH

0
0
0
0
0
0
0
0
III b
III b
0
0
0
0
IV a
IV a
IV a
II b
0
0
0

AB terlalu singkat
AB terlalu singkat
Kultur Resisten
Kultur Resisten
Kultur Resisten
Interval tidak tepat
-

Universitas Sumatera Utara

13
14
15
16
17

18

58

19
20
21
22
23
24
25
26

22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46

Ceftriaxone
Ceftriaxone
Amoksisilin
Metronidazole
Ceftriaxone
Ceftriaxone
Meropenem
Levofloxacin
Amikasin
Ciprofloxacin
Ciprofloxacin
Ceftriaxone
Meropenem
Ceftriaxone
Ceftriaxone
Ceftriaxone
Ceftriaxone
Ceftriaxone
Ciprofloxacin
Ceftriaxone
Ciprofloxacin
Meropenem
Ceftriaxone
Ciprofloxacin
Meropenem

1 gram / 12 jam
1 gram / 12 jam
2 gram / 24 jam
1,5 gram / 24 jam
1 gram / 12 jam
2 gram / 24 jam
1 gram / 8 jam
500 mg / 12 jam
500 mg / 12 jam
200 mg / 24 jam
200 mg / 12 jam
1 gram / 12 jam
1 gram / 12 jam
1 gram / 12 jam
2 gram / 12 jam
1 gram / 12 jam
1 gram / 12 jam
1 gram / 12 jam
200 mg / 12 jam
2 gram / 12 jam
200 mg / 12 jam
1 gram / 8 jam
1 gram / 12 jam
200 mg / 12 jam
1 gram / 12 jam

i.v
i.v
i.v
i.v
i.v
i.v
i.v
p.o
i.v
i.v
i.v
i.v
i.v
i.v
i.v
i.v
i.v
i.v
i.v
i.v
i.v
i.v
i.v
i.v
i.v

4
7
7
9
25

10

14
13
10
7
12
11
12
11

3
4
8
8
7
2
6
21
10
7
6
6
5
11
10
6
7
5
7
2
2
8
3
7
8

6 gram
8 gram
16 gram
12 gram
14 gram
4 gram
18 gram
21 gram
10 gram
1,4 gram
2,4 gram
12 gram
10 gram
22 gram
40 gram
12 gram
14 gram
10 gram
2,8 gram
4 gram
800 mg
24 gram
6 gram
2,8 gram
16 gram

0
0
0
II a
0
0
0
IV a
0
II a
0
0
0
0
0
0
0
0
0
0
V
0
0
0
0

Dosis Tidak tepat
Kultur Resisten
Dosis Tidak tepat
AB tidak diindikasikan
-

Universitas Sumatera Utara

27
28
29

30

31

59

32
33
34
35
36
37
38
39
40
41
42
43

47
48
49
50
51
52
53
54
55
56
57
58
59
60
61
62
63
64
65
66
67
68
69
70
71

Ceftriaxone
Ceftriaxone
Ciprofloxacin
Ceftriaxone
Ceftriaxone
Metronidazole
Gentamisin
Ciprofloxacin
Ampicillin
Meropenem
Gentamisin
Ceftriaxone
Ceftriaxone
Ciprofloxacin
Ciprofloxacin
Ciprofloxacin
Ceftazidime
Ceftazidime
Ceftazidime
Ciprofloxacin
Ceftriaxone
Ceftazidime
Ceftriaxone
Ceftazidime
Ceftriaxone

1 gram / 12 jam
1 gram / 12 jam
400 mg / 12 jam
1 gram / 12 jam
1 gram / 12 jam
500 mg / 8 jam
80 mg / 8 jam
200 mg / 8jam
500 mg / 8 jam
1 gram / 12 jam
80 mg / 8 jam
1 gram / 12 jam
1 gram / 12 jam
400 mg / 12 jam
400 mg / 12 jam
400 mg / 12 jam
1 gram / 12 jam
1 gram / 12 jam
1 gram / 12 jam
200 mg / 12 jam
1 gram / 12 jam
1 gram / 12 jam
2 gram / 12 jam
1 gram / 12 jam
1 gram / 12 jam

i.v
i.v
i.v
i.v
i.v
i.v
i.v
i.v
i.v
i.v
i.v
i.v
i.v
i.v
i.v
i.v
i.v
i.v
i.v
i.v
i.v
i.v
i.v
i.v
i.v

12
7
8

33

12
10
12
15
12
12
11
11
13
14
17
12
12

10
5
4
7
27
17
19
2
7
16
16
13
10
9
8
8
10
10
10
8
2
11
6
12
8

20 gram
10 gram
3,2 gram
14 gram
54 gram
25,5 gram
4,56 gram
800 mg
10,5 gram
52 gram
38,4 gram
26 gram
20 gram
7,2 gram
6,4 gram
6,4 gram
20 gram
20 gram
20 gram
3,2 gram
4 gram
22 gram
24 gram
24 gram
16 gram

0
0
0
0
III a
III a
III a
III b
0
0
III a
0
0
0
0
0
0
0
0
0
III b
0
0
0
0

AB terlalu lama
AB terlalu lama
AB terlalu lama
AB terlalu singkat
AB terlalu lama
AB terlalu singkat
-

Universitas Sumatera Utara

44
45
46
47
48

60

49
50
51
52
53
54
55
56
57

58
59

72
73
74
75
76
77
78
79
80
81
82
83
84
85
86
87
88
89
90
91
92
93
94
95
96
97
98

Ceftazidime
Levofloxacin
Ceftazidime
Ciprofloxacin
Cepefime
Ceftazidime
Ceftazidime
Ciprofloxacin
Ceftazidime
Levofloxacin
Flukonazole
Ceftazidime
Ceftazidime
Ceftazidime
Cefotaxime
Cefotaxime
Gentamisin
Cefotaxime
Cefotaxime
Ceftazidime
Ceftriaxone
cefepime
Ceftriaxone
Amikasin
Meropenem
Ceftazidime
Levofloxacin

1 gram / 12 jam
500 mg / 24 jam
1 gram / 12 jam
400 mg / 12 jam
500 mg / 12 jam
1 gram / 12 jam
1 gram / 12 jam
400 mg / 12 jam
1 gram / 8 jam
500 mg / 24 jam
200 mg / 24 jam
1 gram / 12 jam
1 gram / 24 jam
1 gram / 12 jam
1 gram / 12 jam
1 gram / 12 jam
80 mg / 8 jam
1 gram / 12 jam
1 gram / 12 jam
1 gram / 12 jam
500 mg / 12 jam
400 mg / 12 jam
750 mg / 12 jam
125 mg / 12 jam
1 gram / 12 jam
1 gram / 12 jam
500 mg / 24 jam

i.v
i.v
i.v
i.v
i.v
i.v
i.v
i.v
i.v
i.v
i.v
i.v
i.v
i.v
i.v
i.v
i.v
i.v
i.v
i.v
i.v
i.v
i.v
i.v
i.v
i.v
p.o

9
14
8
14
14
13
9
14
14
14
10
6
5
42

11
24

8
2
7
7
4
4
14
13
9
2
6
13
9
4
10
10
11
11
6
5
7
2
7
9
7
7
8

16 gram
1 gram
14 gram
5,6 gram
4 gram
12 gram
28 gram
10,4 gram
27 gram
1 gram
1,2 gram
26 gram
9 gram
8 gram
20 gram
20 gram
17,6 gram
22 gram
12 gram
10 gram
7 gram
1,6 gram
10, 5 gram
2,25 gram
14 gram
14 gram
4 gram

0
III b
0
0
0
0
0
0
0
III b
0
0
0
0
III a
III a
III a
III a
0
0
0
III b
0
0
0
0
0

AB terlalu singkat
AB terlalu singkat
AB terlalu lama
AB terlalu lama
AB terlalu lama
AB terlalu lama
AB terlalu singkat
-

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60
61
62
63
64
65

99
100
101
102
103
104
105
106
107
108
109

Ceftriaxone
Cefotaxime
Azitromycin
Cefotaxime
Cefotaxime
Cefotaxime
Meropenem
Ciprofloxacin
Levofloxacin
Ciprofloxacin
Meropenem

1 gram / 8 jam
1 gram / 8 jam
500 mg / 24 jam
1 gram / 8 jam
1 gram / 8 jam
1 gram / 12 jam
1 gram / 8 jam
400 mg / 12 jam
500 mg / 24 jam
200 mg / 12 jam
1 gram / 12 jam

i.v
i.v
p.o
i.v
i.v
i.v
i.v
i.v
i.v
i.v
i.v

7
11
7
12
16
19

1
5
5
5
5
6
8
7
16
12
4

3 gram
15 gram
2,5 gram
15 gram
15 gram
12 gram
24 gram
5,6 gram
8 gram
4,8 gram
8 gram

III b
0
0
0
0
0
0
0
0
0
IV a

AB terlalu singkat
Kultur Resisten

61
Universitas Sumatera Utara

Lampiran 3: Tabel Kuantitas Penggunaan Antibiotika Bulan Februari Pada Pasien High Care Unit (HCU) di RSUP H. Adam Malik
No

62

1
2
3

Nama
Pasien
MR
MS
TK

4

NA

5
6
7

MP
LH
NB

8

RT

9

SIN

10

RNG

11

AP

12

RS

13

ST

14

PR

Regimen Antibiotika
Ceftriaxone 2 x 1 g (10 hari)
Ceftriaxone 2 x 1 g (6 hari)
Ceftriaxone 2 x 1 g (9 hari)
Cefotaxime 3 x 100 mg (5 hari)
Gentamisin 2 x 7,5 mg (5 hari)
Ceftriaxone 2 x 1 g (6 hari)
Ceftriaxone 2 x 1 g (11 hari)
Ciprofloxacin 2 x 500 mg (4 hari)
Meropenem 3 x 1 g (1 hari)
Ceftazidime 2 x 1 g (1 hari)
Ceftriaxone 2 x 1 g (7 hari)
Ceftriaxone 1 x 2 g (4 hari)
Levofloxacin 1 x 500 mg (4 hari)
Meropenem 1 x 1 g (3 hari)
Ceftriaxone 2 x 2 g (11 hari)
Ciprofloxacin 1 x 400 mg (7 hari)
Ciprofloxacin 2 x 400 mg (5 hari)
Meropenem 2 x 500 mg (10 hari)
Amikasin 1 x 1 g (4 hari)
Ceftriaxone 2 x 2 g (3 hari)
Meropenem 3 x 1 g (8 hari)
Ceftriaxone 2 x 1 g (3 hari)
Ceftriaxone 2 x 1 g (4 hari)
Amoksisilin 1 x 2 g (8 hari)
Metronidazole 1 x 1,5 g (8 hari)

LOS
17
6
9
5
7
11
16
6
7
7

19

9
4
7

Total
20 gram
12 gram
18 gram
1,5 gram
75 mg
12 gram
22 gram
4 gram
3 gram
2 gram
14 gram
8 gram
2 gram
3 gram
44 gram
2,8 gram
4 gram
10 gram
4 gram
12 gram
24 gram
6 gram
8 gram
16 gram
12 gram

Standar DDD
WHO
2
2
2
4
0,24
2
2
1
2
4
2
2
0,5
2
2
1
1
2
1
2
2
2
2
1
1,5

DDD
20/2 = 10
12/2 = 6
18/2 = 9
1,5/4 = 0,375
0,75/0,24 = 3,125
12/2 = 6
22/2 = 11
4/1 = 4
3/2 = 1,5
2/ 4 = 0,5
14/2 = 7
2/2 = 1
2/0,5 = 4
3/2 = 1,5
44/2 = 22
2,8/1 = 2,8
4/1 = 4
10/2 = 5
4/1 = 4
12/2 = 6
24/2 = 12
6/2 = 3
4/2 = 2
16/1 = 16
12/1,5 = 8

Universitas Sumatera Utara

15

JSS

16

CBS

Ceftriaxone 2 x 1 g (7 hari)
Ceftriaxone 1 x 2 g (2 hari)
Meropenem 3 x 1 g (6 hari)

7
9

14 gram
4 gram
18 gram

2
2
2

14/2 = 7
4/2 = 2
18/2 = 9

63
Universitas Sumatera Utara

Lampiran 4: Tabel Kuantitas Penggunaan Antibiotika Bulan Maret Pada Pasien High Care Unit (HCU) di RSUP H. Adam Malik

64

No

Nama
Pasien

1

NKS

2

NS

3
4
5
6

NP
JT
FR
SD

7

MPS

8

CP

9

CC

10

AS

11

MT

12

KM

13

FN

14

RH

Regimen Antibiotika
Levofloxacin 2 x 500 mg (21 hari)
Amikasin 2 x 500 mg (10 hari)
Ciprofloxacin 1 x 200 mg (7 hari)
Ciprofloxacin 2 x 200 mg (6 hari)
Ceftriaxone 2 x 1 g (6 hari)
Meropenem 2 x 1 g (5 hari)
Ceftriaxone 2 x 1 g (11 hari)
Ceftriaxone 2 x 2 g (10 hari)
Ceftriaxone 2 x 1 g (6 hari)
Ceftriaxone 2 x 1 g (7 hari)
Ceftriaxone 2 x 1 g (5 hari)
Ciprofloxacin 2 x 200 mg (7 hari)
Ceftriaxone 2 x 2 g (2 hari)
Ciprofloxacin 2 x 200 mg (2 hari)
Meropenem 3 x 1 g (8 hari)
Ceftriaxone 2 x 1 g (3 hari)
Ciprofloxacin 2 x 200 mg (7 hari)
Meropenem 2 x 1 g (8 hari)
Ceftriaxone 2 x 1 g (10 hari)
Ceftriaxone 2 x 1 g (5 hari)
Ciprofloxacin 2 x 400 mg (4 hari)
Ceftriaxone 2 x 1 g (7 hari)
Ceftriaxone 2 x 1 g (27 hari)
Metronidazole 8 x 500 mg (17 hari)

LOS
25

10
14
13
10
7
12
11
12
11
12
7
8
33

Total
21 gram
10 gram
7 gram
6 gram
6 gram
5 gram
11 gram
10 gram
6 gram
7 gram
5 gram
7 gram
2 gram
2 gram
8 gram
3 gram
7 gram
8 gram
10 gram
5 gram
4 gram
7 gram
27 gram
17 gram

Standar DDD
WHO
0,5
1
1
1
2
2
2
2
2
2
2
1
2
1
2
2
1
2
2
2
1
2
2
1,5

DDD
21/0,5 = 42
10/1 = 10
7/1 = 7
6/1 = 6
6/2 = 3
5/2 = 2,5
11/2 = 5,5
10/2 = 5
6/2 = 3
7/2 = 3,5
5/2 = 2,5
7/1 = 7
2/2 = 1
2/1 = 2
8/2 = 4
3/2 = 1,5
7/1 = 7
8/2 = 4
10/2 = 5
5/2 = 2,5
4/1 = 4
7/2 = 3,5
27/2 = 13,5
17/1,5 = 11,33

Universitas Sumatera Utara

15

KT

16
17
18
19
20
21
22
23

RP
ST
DS
MS
RS
SR
SM
CZ

Gentamisin 3 x 80 mg (19 hari)
Ciprofloxacin 3 x 200 mg (2 hari)
Ampicillin 3 x 500 mg (7 hari)
Meropenem 2 x 1 g (16 hari)
Gentamisin 3 x 80 mg (16 hari)
Ceftriaxone 2 x 1 g (13 hari)
Ceftriaxone 2 x 2 g (10 hari)
Ciprofloxacin 2 x 400 mg (9 hari)
Ciprofloxacin 2 x 400 mg (8 hari)
Ciprofloxacin 2 x 400 mg (8 hari)
Ceftazidime 2 x 1 g (10 hari)
Ceftazidime 2 x 1 g (10 hari)
Ceftazidime 2 x 1 g (10 hari)

12
10
12
15
12
12
11
11
13

19 gram
2 gram
7 gram
16 gram
16 gram
13 gram
10 gram
9 gram
8 gram
8 gram
10 gram
10 gram
10 gram

0,24
1
2
2
0,24
2
2
1
1
1
4
4
4

19/0,24 = 79,17
2/1 = 2
7/2 = 3,5
16/2 = 8
16/0,24 = 66,67
13/2 = 6,5
10/2 = 5
9/1 = 9
8/1 = 8
8/1 = 8
10/4 = 2,5
10/4 = 2,5
10/4 = 2,5

65
Universitas Sumatera Utara

Lampiran 5: Tabel Kuantitas Penggunaan Antibiotika Bulan April Pada Pasien High Care Unit (HCU) di RSUP H. Adam Malik

1

Nama
Pasien
MH

2

RG

3
4

UB
MS

5

RAS

6

KM

7

RS

8

KR

9

JN

10
11
12
13

RK
RKK
JS
ES

14

JP

15
16

IM
MSS

No

Regimen Antibiotika

66

Ciprofloxacin 2 x 200 mg (8 hari)
Ceftriaxone 2 x 1 g (2 hari)
Ceftazidime 2 x 1 gram (11 hari)
Ceftriaxone 2 x 2g (6 hari)
Ceftazidime 2 x 1 g (12 hari)
Ceftriaxone 2 x 1 g (8 hari
Ceftazidime 2 x 1 g (8 hari)
Levofloxacin 1 x 500 mg (2 hari)
Ceftazidime 2 x 1 g (7 hari)
Ciprofloxacin 2 x 400 mg (7 hari)
Cepefime 2 x 500 mg (4 hari)
Ceftazidime 2 x 1 g (4 hari)
Ceftazidime 2 x 1 g (14 hari)
Ciprofloxacin 2 x 400 mg (13 hari)
Ceftazidime 3 x 1 g (9 hari)
Levofloxacin 1 x 500 mg (2 hari)
Flukonazole 1 x 200 mg (6 hari)
Ceftazidime 2 x 1 g (13 hari)
Ceftazidime 1 x 1 g (9 hari)
Ceftazidime 2 x 1 g (4 hari)
Cefotaxime 2 x 1 g (10 hari)
Cefotaxime 2 x 1 g (10 hari)
Gentamisin 3 x 80 mg (11 hari)
Cefotaxime 2 x 1 g (11 hari)
Cefotaxime 2 x 1 g (6 hari)

LOS

Total

14

3,2 gram
4 gram
22 gram
24 gram
24 gram
16 gram
16 gram
1 gram
14 gram
5,6 gram
4 gram
12 gram
28 gram
10,4 gram
27 gram
1 gram
1,2 gram
26 gram
9 gram
8 gram
20 gram
20 gram
17,6 gram
22 gram
12 gram

17
12
12
9
14
8
14
14
13
9
14
14
14
10
6

Standar DDD
WHO
1
2
4
2
4
2
4
0,5
4
1
2
4
4
1
4
0,5
0,2
4
4
4
4
4
0,24
4
4

DDD
3,2/1 = 3,2
4/2 = 2
22/4 = 5,5
24/2 = 12
24/4 = 6
16/2 = 8
16/4 = 4
1/0,5 = 2
14/4 = 3,5
5,6/1 = 5,6
4/2 = 2
12/4 = 3
28/4 = 7
10,4/1 = 10,4
27/4 = 6,75
1/0,5 = 2
1,2/0,2 = 6
26/4 = 6,5
9/4 = 2,25
8/4 = 2
20/4 = 5
20/4 = 5
17,6/0,24 = 73,33
22/4 = 5,5
12/4 = 3

Universitas Sumatera Utara

67

17

JS

18

BTB

19

MAT

20

MS

21

IS

22
23
24

HA
MT
AR

25

UM

26

RP

Ceftazidime 2 x 1 g (5 hari
Ceftriaxone 2 x 500 mg (7 hari)
Cefepime 2 x 400 mg (2 hari)
Ceftriaxone 2 x 750 mg (7 hari)
Amikasin 2 x 125 mg (9 hari)
Meropenem 2 x 1 g (7 hari)
Ceftazidime 2 x 1 g (7 hari)
Levofloxacin 1 x 500 mg (8 hari)
Ceftriaxone 3 x 1 g (1 hari)
Cefotaxime 3 x 1 g (5 hari)
Azitromycin 1 x 500 mg (5 hari)
Cefotaxime 3 x 1 g (5 hari)
Cefotaxime 3 x 1 g (5 hari)
Cefotaxime 2 x 1 g (6 hari)
Meropenem 3 x 1 g (8 hari)
Ciprofloxacin 2 x 400 mg (7 hari)
Levofloxacin 1 x 500 mg (16 hari)
Ciprofloxacin 2 x 200 mg (12 hari)
Meropenem 2 x 1 g (4 hari)

5
42
11
24
7
11
7
12
16
19

10 gram
7 gram
1,6 gram
10,5 gram
1,25 gram
14 gram
14 gram
4 gram
3 gram
15 gram
2,5 gram
15 gram
15 gram
12 gram
24 gram
5,6 gram
8 gram
4,8 gram
8 gram

2
2
2
2
1
2
4
0,5
2
4
0,3
4
4
4
2
1
0,5
1
2

10/2 = 5
7/2 = 3,5
1,6/2 = 0,8
10,5/2 = 5,25
1,25/1 = 1,25
14/2 = 7
14/4 = 3,5
4/0,5 = 8
3/2 = 1.5
15/4 = 3,75
2,5/0,3 = 8,33
15/4 = 3,75
15/4 = 3,75
12/4 = 3
24/2 = 12
5,6/1 = 5,6
8/0,5 = 16
4,8/1 = 4,8
8/2 = 4

Universitas Sumatera Utara

Lampiran 6. Surat Izin Penelitian / Pengambilan Data dari Fakultas

68
Universitas Sumatera Utara

Lampiran 7. Surat Izin Penelitian dari Litbang

69
Universitas Sumatera Utara

Lampiran 8. Surat Izin Penelitian Untuk ke Ruangan

70
Universitas Sumatera Utara

Lampiran 9. Surat Izin Telah Selesai Melaksanakan Penelitian di RSUP
H. Adam Malik

71
Universitas Sumatera Utara