Pengaruh Penambahan Ekstrak Kulit Manggis (Garcinia X Mangostana L.) Terhadap Nilai Spf Krim Tabir Surya Kombinasi Avobenson Dan Oktil Metoksisinamat

PENGARUH PENAMBAHAN EKSTRAK KULIT MANGGIS
(Garcinia x mangostana L.) TERHADAP NILAI SPF
KRIM TABIR SURYA KOMBINASI
AVOBENSON DAN OKTIL METOKSISINAMAT
Abstrak
Paparan berlebihan radiasi UV dapat menyebabkan efek akut dan kronis
pada kulit. Radiasi UV dapat menyebabkan efek akut kulit seperti radang, eritema,
pigmentasi, dan efek kronis seperti kanker dan penuaan dini. Penggunaan tabir
surya topikal adalah cara untuk melindungi efek merugikan radiasi UV pada kulit.
Ekstrak kulit manggis (Garcinia x mangostana L.) merupakan sumber alami
flavonoid yang memiliki potensi fotoproteksi karena dapat menyerap sinar UV dan
befungsi sebagai antioksidan secara langsung dan tidak langsung. Tujuan
penelitian ini adalah untuk mengetahui pengaruh ekstrak kulit manggis terhadap
nilai SPF dan stabilitas fisik krim tabir surya yang mengandung kombinasi
avobenson dan oktil metoksisinamat.
Pada penelitian ini, kulit manggis diekstraksi dengan metode perkolasi
menggunakan etanol 70% kemudian ekstrak dikeringkan menggunakan penangas
air pada suhu 80-90ºC. Krim tabir surya mengandung asam stearat dan
trietanolamin sebagai basis krim. Krim tabir surya kombinasi avobenson dan oktil
metoksisinamat diformulasikan dengan penambahan ekstrak kulit manggis dengan
konsentrasi 4% (FI), 6% (FII), 8% (FIII), dan 10% (FIV). Evaluasi krim meliputi

homogenitas krim, tipe emulsi, pH, stabilitas (pemisahan fase, warna dan bau),
iritasi kulit, dan nilai SPF. Nilai SPF krim tabir surya ditentukan dengan metode
spektrofotometri UV-Visible menggunakan persamaan Mansur.
Hasil penelitian menunjukkan bahwa semua sediaan homogen, tipe emulsi
m/a, pH 5,1 - 6,4, tidak mengiritasi, dan stabil selama 12 minggu penyimpanan
pada suhu kamar. Nilai SPF meningkat dengan meningkatnya konsentrasi ekstrak
kulit manggis. Nilai SPF krim tabir surya yang mengandung ekstrak 4% (FI), 6%
(FII), 8% (FIII), dan 10% (FIV) masing-masing adalah 14,0176, 16,5981,
18,5802, 24,6947. Dapat disimpulkan bahwa ekstrak kulit manggis dapat
meningkatkan nilai SPF krim tabir surya kombinasi avobenson dan oktil
metoksisinamat.
Kata kunci : ekstrak kulit manggis, avobenson, oktil metoksisinamat, nilai SPF,
tabir surya.

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THE EFFECT OF MANGOSTEEN PERICARP EXTRACT
(Garcinia x mangostana L.) ADDITION ON SUNSCREEN
CREAM’S SPF VALUE OF AVOBENZONE AND OCTYL
METHOXYCINNAMATE COMBINATION

Abstract
Overexposure to UV radiation can cause acute and chronic effects on the
skin. The UV radiation induces responses on acute skin effects such as
inflammation, erythema, pigmentation, and chronic effects such as
photocarcinogenesis and photoaging. Topical application of sunscreen is a
strategy to protect the deleterious effect of UV radiation on the skin. The
mangosteen pericarp extract (Garcinia x mangostana L.) is a natural source of
flavonoids that have the potential photoprotection because of their UV absorbing
and their ability to act as direct and indirect antioxidants. The purpose of this
study was to understand the effect of mangosteen pericarp extract on SPF value
and physical stability of sunscreen cream containing a combination of avobenzone
and octyl methoxycinnamate.
In this study, mangosteen pericarp was extracted by percolation method
using 70% ethanol. Then extract was dried using a waterbath at 80-90ºC.
Sunscreen cream containing stearic acid and triethanolamine as cream bases.
Sunscreen creams of avobenzone and octyl methoxycinnamate combination were
formulated with addition of mangosteen pericarp extract at a concentration of 4%
(FI), 6% (FII), 8% (FIII), and 10% (FIV). Evaluations conducted on cream such as
homogenity, emulsion type, pH, stability (phase separation, color, and odor), skin
irritation, and SPF value. SPF value of sunscreens were determined by UVVisible spectrophotometry method using Mansur equation.

The study results showed that all the samples were homogeneous,
emulsion type m/a, pH was 5.1 – 6.4, non-irritating, and were stable during 12
weeks of storage at room temperature. SPF value increased by increasing the
mangosteen pericarp extract concentration. Sunscreen cream’s SPF value that
contained of 4% (FI), 6% (FII), 8% (FIII), and 10% (FIV) extract were 14.0176,
16.5981, 18.5802, 24.6947 respectively. It can be concluded that mangosteen
pericarp extract can increases the sunscreen cream’s SPF value of combination
avobenzone and octyl methoxycinnamate.
Key words: mangosteen pericarp extract, avobenzone, octyl methoxycinnamate, SPF
value, sunscreen.

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