Lampiran 1Hasil pengukuran waktu alir granul PENGGUNAAN POLIETILENGLIKOL 4000 DALAM BERBAGAI KOSENTRASI SEBAGAI BAHAN PELICIN PEMBUATAN TABLET EFFERVESCENT FeSO4 DAN VITAMIN C.
45
Lampiran 1
Hasil pengukuran waktu alir granul
Replikasi
FI
9.51
8.96
8.27
8.91
0.62
1
2
3
Mean
SD
F II
9.18
8
8.37
8.52
0.60
Waktu alir (detik)
F III
8.43
8.17
8.51
8.37
0.18
F IV
7.23
8.09
8.12
7.81
0.505
FV
6.34
5.95
6.14
6.14
0.195
Oneway
Descriptives
Waktu Alir
N
Formula I
Formula II
Formula III
Formula IV
Formula V
Total
3
3
3
3
3
15
Mean
8.9133
8.5167
8.3700
7.8133
6.1433
7.9513
Std.
Deviation
.6213
.6035
.1778
.5054
.1950
1.0782
Std.
Error
.3587
.3484
.1026
.2918
.1126
.2784
Test of Homogeneity of Variances
Waktu Alir
Levene
Statistic
1.669
df1
df2
4
10
Sig.
.233
95% Confidence
Interval for Mean
Lower
Upper
Bound
Bound
7.3699
10.4568
7.0174
10.0159
7.9284
8.8116
6.5578
9.0688
5.6589
6.6278
7.3542
8.5484
Minimum
8.27
8.00
8.17
7.23
5.95
5.95
Maximum
9.51
9.18
8.51
8.12
6.34
9.51
46
ANOVA
Waktu Alir
Between Groups
Within Groups
Total
Sum of
Squares
14.125
2.151
16.275
df
4
10
14
Mean Square
3.531
.215
F
16.419
Sig.
.000
Post Hoc Tests
Multiple Comparisons
Dependent Variable: Waktu Alir
Scheffe
(I) Perlakuan
Formula I
Formula II
Formula III
Formula IV
Formula V
(J) Perlakuan
Formula II
Formula III
Formula IV
Formula V
Formula I
Formula III
Formula IV
Formula V
Formula I
Formula II
Formula IV
Formula V
Formula I
Formula II
Formula III
Formula V
Formula I
Formula II
Formula III
Formula IV
Mean
Difference
(I-J)
.3967
.5433
1.1000
2.7700*
-.3967
.1467
.7033
2.3733*
-.5433
-.1467
.5567
2.2267*
-1.1000
-.7033
-.5567
1.6700*
-2.7700*
-2.3733*
-2.2267*
-1.6700*
Std. Error
.3787
.3787
.3787
.3787
.3787
.3787
.3787
.3787
.3787
.3787
.3787
.3787
.3787
.3787
.3787
.3787
.3787
.3787
.3787
.3787
*. The mean difference is significant at the .05 level.
Sig.
.888
.727
.154
.001
.888
.997
.519
.002
.727
.997
.710
.003
.154
.519
.710
.019
.001
.002
.003
.019
95% Confidence Interval
Lower Bound Upper Bound
-1.0157
1.8090
-.8690
1.9557
-.3123
2.5123
1.3577
4.1823
-1.8090
1.0157
-1.2657
1.5590
-.7090
2.1157
.9610
3.7857
-1.9557
.8690
-1.5590
1.2657
-.8557
1.9690
.8143
3.6390
-2.5123
.3123
-2.1157
.7090
-1.9690
.8557
.2577
3.0823
-4.1823
-1.3577
-3.7857
-.9610
-3.6390
-.8143
-3.0823
-.2577
47
Lampiran 2
Hasil pengukuran sudut diam granul
Replikasi
FI
30.68
33.47
32.78
32.31
1.45
1
2
3
Mean
SD
Sudut diam (°)
F III
32.35
29.54
30.47
30.79
1.43
F II
31.3
31.56
31.3
31.39
0.15
F IV
31.5
29.45
30.61
30.52
1.03
FV
28.47
28.27
27.32
28.02
0.61
Oneway
Descriptives
Sudut Diam
N
Formula I
Formula II
Formula III
Formula IV
Formula V
Total
3
3
3
3
3
15
Mean
32.3100
31.3867
30.7867
30.5200
28.0200
30.6047
Std.
Deviation
1.4532
.1501
1.4315
1.0280
.6144
1.7312
Std.
Error
.8390
.0867
.8265
.5935
.3547
.4470
Test of Homogeneity of Variances
Sudut Diam
Levene
Statistic
2.241
df1
df2
4
10
Sig.
.137
95% Confidence
Interval for Mean
Lower
Upper
Bound
Bound
28.7001
35.9199
31.0138
31.7596
27.2306
34.3427
27.9664
33.0736
26.4937
29.5463
29.6460
31.5634
Minimum
30.68
31.30
29.54
29.45
27.32
27.32
Maximum
33.47
31.56
32.35
31.50
28.47
33.47
48
ANOVA
Sudut Diam
Between Groups
Within Groups
Total
Sum of
Squares
30.721
11.235
41.957
df
4
10
14
Mean Square
7.680
1.124
F
6.836
Sig.
.006
Post Hoc Tests
Multiple Comparisons
Dependent Variable: Sudut Diam
Scheffe
(I) Perlakuan
Formula I
Formula II
Formula III
Formula IV
Formula V
(J) Perlakuan
Formula II
Formula III
Formula IV
Formula V
Formula I
Formula III
Formula IV
Formula V
Formula I
Formula II
Formula IV
Formula V
Formula I
Formula II
Formula III
Formula V
Formula I
Formula II
Formula III
Formula IV
Mean
Difference
(I-J)
.9233
1.5233
1.7900
4.2900*
-.9233
.6000
.8667
3.3667*
-1.5233
-.6000
.2667
2.7667
-1.7900
-.8667
-.2667
2.5000
-4.2900*
-3.3667*
-2.7667
-2.5000
Std. Error
.8655
.8655
.8655
.8655
.8655
.8655
.8655
.8655
.8655
.8655
.8655
.8655
.8655
.8655
.8655
.8655
.8655
.8655
.8655
.8655
*. The mean difference is significant at the .05 level.
Sig.
.881
.566
.421
.009
.881
.972
.903
.040
.566
.972
.999
.104
.421
.903
.999
.158
.009
.040
.104
.158
95% Confidence Interval
Lower Bound Upper Bound
-2.3048
4.1514
-1.7048
4.7514
-1.4381
5.0181
1.0619
7.5181
-4.1514
2.3048
-2.6281
3.8281
-2.3614
4.0948
.1386
6.5948
-4.7514
1.7048
-3.8281
2.6281
-2.9614
3.4948
-.4614
5.9948
-5.0181
1.4381
-4.0948
2.3614
-3.4948
2.9614
-.7281
5.7281
-7.5181
-1.0619
-6.5948
-.1386
-5.9948
.4614
-5.7281
.7281
49
Lampiran 3
Hasil uji keseragaman bobot tablet
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
FI
2.98
2.97
2.97
3
2.94
2.95
2.89
2.98
2.99
3.01
2.98
2.97
2.88
2.9
2.97
3.01
2.98
3.02
2.96
2.99
F II
3
3.01
2.98
2.99
2.99
2.96
3
2.99
2.98
2.95
2.96
2.87
2.91
3.01
2.99
2.97
2.96
3.02
2.99
3
Bobot tablet (g)
F III
2.98
3.03
3.05
3
2.98
3
2.96
2.98
3
2.95
3.04
2.96
2.98
2.97
3.02
3.05
3.07
3.02
3
2.98
Mean
2.967
2.9765
3.001
2.999
3.003
SD
0.039
0.036
0.034
0.042
0.038
CV
1.30
1.195
1.13
1.39
1.28
Replikasi
F IV
3.02
3
3.05
2.99
2.89
3.02
2.99
2.96
2.97
3.05
2.99
3.07
3.03
3
3.03
2.98
3.02
3
2.99
2.93
FV
3.05
3
2.95
3.04
3.02
2.98
2.93
2.94
3.02
3.03
2.99
3.04
3.02
3
3.08
3.02
3
2.96
2.98
3.01
50
Perhitungan keseragaman bobot tablet menurut Farmakope Indonesia :
1. Formula I
Bobot rata-rata 20 tablet = 2,967 g
5
x Untuk penyimpangan 5% =
x 2,967 g 0,148 g
100
Jadi berat tablet = 2,967 g + 0,148 g (2,819 g – 3,115 g)
10
x Untuk penyimpangan 10% =
x 2,967 g 0,297 g
100
Jadi berat tablet = 2,967 g + 0,297 g (2,67 g – 3,264 g)
2. Formula II
Bobot rata-rata 20 tablet = 2,9765 g
5
x Untuk penyimpangan 5% =
x 2,97 65 g 0,149 g
100
Jadi berat tablet = 2,9765 g + 0,149 g (2,8275 g – 3,1255 g)
10
x Untuk penyimpangan 10% =
x 2,9765 g 0,298 g
100
Jadi berat tablet = 2,9765 g + 0,298 g (2,6785 g – 3,274 g)
3. Formula III
Bobot rata-rata 20 tablet = 3,001 g
5
x Untuk penyimpangan 5% =
x 3,001 g 0,15 g
100
Jadi berat tablet = 3,001 g + 0,15 g (2,851 g – 3,151 g)
10
x Untuk penyimpangan 10% =
x 3,001 g 0,30 g
100
Jadi berat tablet = 3,001 g + 0,30 g (2,701 g – 3,301 g)
4. Formula IV
Bobot rata-rata 20 tablet = 2,999 g
5
x Untuk penyimpangan 5% =
x 2,999 g 0,15 g
100
Jadi berat tablet = 2,999 g + 0,15 g (2,849 g – 3,149 g)
10
x Untuk penyimpangan 10% =
x 2,999 g 0,30 g
100
Jadi berat tablet = 2,999 g + 0,30 g (2,699 g – 3,299 g)
51
5. Formula V
Bobot rata-rata 20 tablet = 3,003 g
5
x Untuk penyimpangan 5% =
x 3,003 g 0,15 g
100
Jadi berat tablet = 3,003 g + 0,15 g (2,853 g – 3,153 g)
10
x Untuk penyimpangan 10% =
x 3,003 g 0,30 g
100
Jadi berat tablet = 3,003 g + 0,30 g (2,703 g – 3,303 g)
Oneway
Descriptives
Keseragaman Bobot
Formula I
Formula II
Formula III
Formula IV
Formula V
Total
N
20
20
20
20
20
100
Mean
2.9670
2.9765
3.0010
2.9990
3.0030
2.9893
Std.
Deviation
.03868
.03558
.03386
.04179
.03840
.03983
Std.
Error
.00865
.00796
.00757
.00934
.00859
.00398
95% Confidence
Interval for Mean
Lower
Upper
Bound
Bound
2.9489
2.9851
2.9598
2.9932
2.9852
3.0168
2.9794
3.0186
2.9850
3.0210
2.9814
2.9972
Minimum
2.88
2.87
2.95
2.89
2.93
2.87
Maximum
3.02
3.02
3.07
3.07
3.08
3.08
Test of Homogeneity of Variances
Keseragaman Bobot
Levene
Statistic
.126
df1
df2
4
Sig.
.973
95
ANOVA
Keseragaman Bobot
Between Groups
Within Groups
Total
Sum of
Squares
.022
.135
.157
df
4
95
99
Mean Square
.005
.001
F
3.787
Sig.
.007
52
Post Hoc Tests
Multiple Comparisons
Dependent Variable: Keseragaman Bobot
Scheffe
(I) Perlakuan
Formula I
Formula II
Formula III
Formula IV
Formula V
(J) Perlakuan
Formula II
Formula III
Formula IV
Formula V
Formula I
Formula III
Formula IV
Formula V
Formula I
Formula II
Formula IV
Formula V
Formula I
Formula II
Formula III
Formula V
Formula I
Formula II
Formula III
Formula IV
Mean
Difference
(I-J)
-.0095
-.0340
-.0320
-.0360
.0095
-.0245
-.0225
-.0265
.0340
.0245
.0020
-.0020
.0320
.0225
-.0020
-.0040
.0360
.0265
.0020
.0040
Std.
Error
.01194
.01194
.01194
.01194
.01194
.01194
.01194
.01194
.01194
.01194
.01194
.01194
.01194
.01194
.01194
.01194
.01194
.01194
.01194
.01194
Sig.
.959
.097
.136
.067
.959
.385
.475
.303
.097
.385
1.000
1.000
.136
.475
1.000
.998
.067
.303
1.000
.998
95% Confidence
Interval
Lower
Upper
Bound
Bound
-.0470
.0280
-.0715
.0035
-.0695
.0055
-.0735
.0015
-.0280
.0470
-.0620
.0130
-.0600
.0150
-.0640
.0110
-.0035
.0715
-.0130
.0620
-.0355
.0395
-.0395
.0355
-.0055
.0695
-.0150
.0600
-.0395
.0355
-.0415
.0335
-.0015
.0735
-.0110
.0640
-.0355
.0395
-.0335
.0415
53
Lampiran 4
Hasil uji kekerasan tablet
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
FI
5.35
5.38
5.23
5.09
5.05
4.74
4.84
5.26
6.51
4.47
5.93
4.08
4.86
5.22
6.12
5.48
6.03
4.83
4.84
6.07
Kekerasan tablet (kg)
F II
F III
F IV
6.25
7.84
7.34
6.31
6.34
7.06
5.3
6.13
6.69
6.3
5.6
7.65
5.55
5.91
7.42
5.95
5.53
7.13
6.76
5.09
6.85
7.14
6.81
7.11
6.14
7.49
5.96
6.27
7.71
6.97
6.06
6.18
6.77
7.69
7.86
6.57
6.3
6.96
6.72
5.87
7.38
6.47
6.6
6.46
6.27
7.61
6.44
6.61
6.58
5.31
7.54
6.65
6.11
7.47
6.01
6.63
7.35
6.55
5.87
7.65
FV
6.29
7.47
7.67
7.66
6.77
6.96
7.43
6.55
7.49
6.86
7.38
6.35
7.47
6.81
7.85
7.39
6.05
7.03
6.96
7.42
Mean
5.27
6.39
6.48
6.98
7.09
SD
0.61
0.65
0.84
0.47
0.51
Replikasi
54
Oneway
Descriptives
Kekerasan Tablet
Formula I
Formula II
Formula III
Formula IV
Formula V
Total
N
20
20
20
20
20
100
Std.
Deviation
.6126
.5974
.8431
.4746
.5088
.8903
Mean
5.2690
6.3945
6.4825
6.9800
7.0930
6.4438
Std.
Error
.1370
.1336
.1885
.1061
.1138
.0890
95% Confidence
Interval for Mean
Lower
Upper
Bound
Bound
4.9823
5.5557
6.1149
6.6741
6.0879
6.8771
6.7579
7.2021
6.8549
7.3311
6.2671
6.6205
Minimum
4.08
5.30
5.09
5.96
6.05
4.08
Maximum
6.51
7.69
7.86
7.65
7.85
7.86
Test of Homogeneity of Variances
Kekerasan Tablet
Levene
Statistic
2.047
df1
df2
4
Sig.
.094
95
ANOVA
Kekerasan Tablet
Between Groups
Within Groups
Total
Sum of
Squares
41.861
36.613
78.474
df
4
95
99
Mean Square
10.465
.385
F
27.155
Sig.
.000
55
Post Hoc Tests
Multiple Comparisons
Dependent Variable: Kekerasan Tablet
Scheffe
(I) Perlakuan
Formula I
Formula II
Formula III
Formula IV
Formula V
(J) Perlakuan
Formula II
Formula III
Formula IV
Formula V
Formula I
Formula III
Formula IV
Formula V
Formula I
Formula II
Formula IV
Formula V
Formula I
Formula II
Formula III
Formula V
Formula I
Formula II
Formula III
Formula IV
Mean
Difference
(I-J)
-1.1255*
-1.2135*
-1.7110*
-1.8240*
1.1255*
-.0880
-.5855
-.6985*
1.2135*
.0880
-.4975
-.6105
1.7110*
.5855
.4975
-.1130
1.8240*
.6985*
.6105
.1130
95% Confidence Interval
Std. Error
.1963
.1963
.1963
.1963
.1963
.1963
.1963
.1963
.1963
.1963
.1963
.1963
.1963
.1963
.1963
.1963
.1963
.1963
.1963
.1963
*. The mean difference is significant at the .05 level.
Sig.
.000
.000
.000
.000
.000
.995
.072
.017
.000
.995
.179
.054
.000
.072
.179
.988
.000
.017
.054
.988
Lower Bound
-1.7423
-1.8303
-2.3278
-2.4408
.5087
-.7048
-1.2023
-1.3153
.5967
-.5288
-1.1143
-1.2273
1.0942
-.0313
-.1193
-.7298
1.2072
.0817
-.0063
-.5038
Upper Bound
-.5087
-.5967
-1.0942
-1.2072
1.7423
.5288
.0313
-.0817
1.8303
.7048
.1193
.0063
2.3278
1.2023
1.1143
.5038
2.4408
1.3153
1.2273
.7298
56
Lampiran 5
Hasil uji kerapuhan tablet
Kerapuhan tablet (%)
F II
F III
F IV
0.202
0.151
0.117
0.219
0.219
0.201
0.422
0.253
0.285
Replikasi
1
2
3
FI
0.253
0.355
0.304
FV
0.117
0.218
0.167
Mean
0.30
0.28
0.22
0.20
0.17
SD
0.05
0.12
0.05
0.08
0.05
Oneway
Descriptives
Kerapuhan Tablet
N
Formula I
Formula II
Formula III
Formula IV
Formula V
Total
3
3
3
3
3
15
Mean
.3040
.2810
.2077
.2010
.1673
.2322
Std.
Deviation
.0510
.1224
.0519
.0840
.0505
.0844
Std.
Error
.0294
.0707
.0300
.0485
.0292
.0218
Test of Homogeneity of Variances
Kerapuhan Tablet
Levene
Statistic
1.557
df1
df2
4
10
Sig.
.259
95% Confidence
Interval for Mean
Lower
Upper
Bound
Bound
.1773
.4307
-.0231
.5851
.0787
.3367
-.0077
.4097
.0419
.2928
.1855
.2789
Minimum
.25
.20
.15
.12
.12
.12
Maximum
.36
.42
.25
.28
.22
.42
57
ANOVA
Kerapuhan Tablet
Between Groups
Within Groups
Total
Sum of
Squares
.040
.060
.100
df
4
10
14
Mean Square
.010
.006
F
1.671
Sig.
.232
Lampiran 6
Hasil uji waktu larut tablet
a. Suhu 10°C
Replikasi
Waktu larut (menit)
F III
F IV
8.58
8.9
8.83
9.17
9.2
8.47
7.67
8.27
9.75
8.37
9.92
10.22
7.5
9.35
8.25
9.55
9.92
9.25
9.97
10.68
1
2
3
4
5
6
7
8
9
10
FI
3.48
3.63
2.63
2.55
3.01
3.48
4.23
4.02
3.03
4.05
F II
6.77
6.68
7.92
6.6
7.25
7.82
8.2
8.42
8.53
8.58
FV
8.22
8.07
9.42
8.1
10.02
9.15
11.22
10.13
11.77
11.3
Mean
3.41
7.68
8.96
9.22
9.74
SD
0.59
0.79
0.94
0.785
1.38
58
Oneway
Descriptives
Waktu Larut 10
Formula I
Formula II
Formula III
Formula IV
Formula V
Total
N
10
10
10
10
10
50
Mean
3.4110
7.6770
8.9590
9.2230
9.7400
7.8020
Std.
Deviation
.5930
.7893
.9432
.7853
1.3830
2.4893
Std.
Error
.1875
.2496
.2983
.2483
.4374
.3520
Test of Homogeneity of Variances
Waktu Larut 10
Levene
Statistic
3.050
df1
df2
4
45
Sig.
.026
95% Confidence
Interval for Mean
Lower
Upper
Bound
Bound
2.9868
3.8352
7.1124
8.2416
8.2843
9.6337
8.6612
9.7848
8.7506
10.7294
7.0945
8.5095
Minimum
2.55
6.60
7.50
8.27
8.07
2.55
Maximum
4.23
8.58
9.97
10.68
11.77
11.77
59
Post Hoc Tests
Multiple Comparisons
Dependent Variable: Waktu Larut 10
Scheffe
(I) Perlakuan
Formula I
Formula II
Formula III
Formula IV
Formula V
(J) Perlakuan
Formula II
Formula III
Formula IV
Formula V
Formula I
Formula III
Formula IV
Formula V
Formula I
Formula II
Formula IV
Formula V
Formula I
Formula II
Formula III
Formula V
Formula I
Formula II
Formula III
Formula IV
Mean
Difference
(I-J)
-4.2660*
-5.5480*
-5.8120*
-6.3290*
4.2660*
-1.2820
-1.5460*
-2.0630*
5.5480*
1.2820
-.2640
-.7810
5.8120*
1.5460*
.2640
-.5170
6.3290*
2.0630*
.7810
.5170
Std. Error
.4192
.4192
.4192
.4192
.4192
.4192
.4192
.4192
.4192
.4192
.4192
.4192
.4192
.4192
.4192
.4192
.4192
.4192
.4192
.4192
*. The mean difference is significant at the .05 level.
Sig.
.000
.000
.000
.000
.000
.070
.016
.001
.000
.070
.982
.491
.000
.016
.982
.822
.000
.001
.491
.822
95% Confidence Interval
Lower Bound Upper Bound
-5.6124
-2.9196
-6.8944
-4.2016
-7.1584
-4.4656
-7.6754
-4.9826
2.9196
5.6124
-2.6284
.0644
-2.8924
-.1996
-3.4094
-.7166
4.2016
6.8944
-.0644
2.6284
-1.6104
1.0824
-2.1274
.5654
4.4656
7.1584
.1996
2.8924
-1.0824
1.6104
-1.8634
.8294
4.9826
7.6754
.7166
3.4094
-.5654
2.1274
-.8294
1.8634
60
b. Suhu 25°C
Replikasi
Waktu larut (menit)
1
2
3
4
5
6
7
8
9
10
FI
2.01
2.02
2.03
2.82
1.52
2.5
1.95
2.12
1.45
1.8
F II
3.03
3.04
3.5
3.23
3.37
3.62
3.5
3.75
3.78
4.15
F III
3.06
3.5
4.15
3.75
5.25
4.15
4.37
4.62
5.58
5.65
F IV
5.12
5.15
5.23
4.83
4.36
5.68
5.65
4.98
5.77
5.4
FV
4.25
5.25
5.47
5.03
5.38
5.65
5.95
5.37
5.42
5.52
2.02
3.50
4.41
5.21
5.33
0.41
0.35
0.87
0.43
0.45
Mean
SD
Oneway
Descriptives
Waktu Larut 25
N
Formula I
Formula II
Formula III
Formula IV
Formula V
Total
10
10
10
10
10
50
Mean
2.0220
3.4970
4.4080
5.2170
5.3290
4.0946
Std.
Deviation
.4094
.3496
.8743
.4341
.4494
1.3428
Std.
Error
.1295
.1106
.2765
.1373
.1421
.1899
Test of Homogeneity of Variances
Waktu Larut 25
Levene
Statistic
3.109
df1
df2
4
45
Sig.
.024
95% Confidence
Interval for Mean
Lower
Upper
Bound
Bound
1.7291
2.3149
3.2469
3.7471
3.7826
5.0334
4.9065
5.5275
5.0075
5.6505
3.7130
4.4762
Minimum
1.45
3.03
3.06
4.36
4.25
1.45
Maximum
2.82
4.15
5.65
5.77
5.95
5.95
61
ANOVA
Waktu Larut 25
Between Groups
Within Groups
Total
Sum of
Squares
75.345
13.001
88.346
df
4
45
49
Mean Square
18.836
.289
F
65.198
Sig.
.000
Post Hoc Tests
Multiple Comparisons
Dependent Variable: Waktu Larut 25
Scheffe
(I) Perlakuan
Formula I
Formula II
Formula III
Formula IV
Formula V
(J) Perlakuan
Formula II
Formula III
Formula IV
Formula V
Formula I
Formula III
Formula IV
Formula V
Formula I
Formula II
Formula IV
Formula V
Formula I
Formula II
Formula III
Formula V
Formula I
Formula II
Formula III
Formula IV
Mean
Difference
(I-J)
-1.4750*
-2.3860*
-3.1950*
-3.3070*
1.4750*
-.9110*
-1.7200*
-1.8320*
2.3860*
.9110*
-.8090*
-.9210*
3.1950*
1.7200*
.8090*
-.1120
3.3070*
1.8320*
.9210*
.1120
Std. Error
.2404
.2404
.2404
.2404
.2404
.2404
.2404
.2404
.2404
.2404
.2404
.2404
.2404
.2404
.2404
.2404
.2404
.2404
.2404
.2404
*. The mean difference is significant at the .05 level.
Sig.
.000
.000
.000
.000
.000
.013
.000
.000
.000
.013
.035
.011
.000
.000
.035
.994
.000
.000
.011
.994
95% Confidence Interval
Lower Bound Upper Bound
-2.2470
-.7030
-3.1580
-1.6140
-3.9670
-2.4230
-4.0790
-2.5350
.7030
2.2470
-1.6830
-.1390
-2.4920
-.9480
-2.6040
-1.0600
1.6140
3.1580
.1390
1.6830
-1.5810
-.0370
-1.6930
-.1490
2.4230
3.9670
.9480
2.4920
.0370
1.5810
-.8840
.6600
2.5350
4.0790
1.0600
2.6040
.1490
1.6930
-.6600
.8840
62
c. Suhu 35°C
Replikasi
1
2
3
4
5
6
7
8
9
10
FI
1.15
0.98
1.18
1.53
0.85
0.98
1.42
1.08
1.15
1.22
F II
1.97
1.27
1.12
1.33
1.05
1.18
1.32
1.03
1.27
1.3
Waktu larut (menit)
F III
2.75
2.23
2.43
2.5
2.03
2.07
2.05
2.55
2.9
2.58
1.15
1.28
2.41
3.13
3.42
0.20
0.26
0.30
0.66
0.36
Mean
SD
F IV
2.37
3.38
3.85
3.92
2.23
2.83
2.25
3.5
3.58
3.43
FV
3.05
3.27
3.35
3.85
3.97
3.37
3.22
3.08
3.92
3.08
Oneway
Descriptives
Waktu Larut 35
N
Formula I
Formula II
Formula III
Formula IV
Formula V
Total
10
10
10
10
10
50
Mean
1.1540
1.2840
2.4090
3.1340
3.4160
2.2794
Std.
Deviation
.2043
.2649
.3045
.6571
.3614
1.0088
Std.
Error
.0646
.0838
.0963
.2078
.1143
.1427
Test of Homogeneity of Variances
Waktu Larut 35
Levene
Statistic
8.059
df1
df2
4
45
Sig.
.000
95% Confidence
Interval for Mean
Lower
Upper
Bound
Bound
1.0079
1.3001
1.0945
1.4735
2.1911
2.6269
2.6639
3.6041
3.1575
3.6745
1.9927
2.5661
Minimum
.85
1.03
2.03
2.23
3.05
.85
Maximum
1.53
1.97
2.90
3.92
3.97
3.97
63
ANOVA
Waktu Larut 35
Between Groups
Within Groups
Total
Sum of
Squares
42.963
6.903
49.867
df
4
45
49
Mean Square
10.741
.153
F
70.014
Sig.
.000
Post Hoc Tests
Multiple Comparisons
Dependent Variable: Waktu Larut 35
Scheffe
(I) Perlakuan
Formula I
Formula II
Formula III
Formula IV
Formula V
(J) Perlakuan
Formula II
Formula III
Formula IV
Formula V
Formula I
Formula III
Formula IV
Formula V
Formula I
Formula II
Formula IV
Formula V
Formula I
Formula II
Formula III
Formula V
Formula I
Formula II
Formula III
Formula IV
Mean
Difference
(I-J)
-.1300
-1.2550*
-1.9800*
-2.2620*
.1300
-1.1250*
-1.8500*
-2.1320*
1.2550*
1.1250*
-.7250*
-1.0070*
1.9800*
1.8500*
.7250*
-.2820
2.2620*
2.1320*
1.0070*
.2820
Std. Error
.1752
.1752
.1752
.1752
.1752
.1752
.1752
.1752
.1752
.1752
.1752
.1752
.1752
.1752
.1752
.1752
.1752
.1752
.1752
.1752
*. The mean difference is significant at the .05 level.
Sig.
.967
.000
.000
.000
.967
.000
.000
.000
.000
.000
.005
.000
.000
.000
.005
.631
.000
.000
.000
.631
95% Confidence Interval
Lower Bound Upper Bound
-.6926
.4326
-1.8176
-.6924
-2.5426
-1.4174
-2.8246
-1.6994
-.4326
.6926
-1.6876
-.5624
-2.4126
-1.2874
-2.6946
-1.5694
.6924
1.8176
.5624
1.6876
-1.2876
-.1624
-1.5696
-.4444
1.4174
2.5426
1.2874
2.4126
.1624
1.2876
-.8446
.2806
1.6994
2.8246
1.5694
2.6946
.4444
1.5696
-.2806
.8446
64
d. Suhu 60°C
Replikasi
1
2
3
4
5
6
7
8
9
10
FI
1.08
0.95
0.72
0.8
0.82
0.83
0.68
0.8
0.68
0.78
F II
0.98
1
0.9
0.95
1.02
1.13
0.95
1.2
0.97
0.93
Waktu larut (menit)
F III
1.07
0.98
1.18
1.53
0.85
0.98
1.42
1.08
1.15
1.22
0.81
1.00
1.15
1.21
1.35
0.12
0.09
0.21
0.13
0.31
Mean
SD
F IV
1.45
1.13
1.22
1.13
1.1
1.18
1.4
1.17
1.27
1.03
FV
1.02
1.2
1.55
1.82
1.67
1.02
1.43
0.95
1.23
1.65
Oneway
Descriptives
Waktu Larut 60
Formula I
Formula II
Formula III
Formula IV
Formula V
Total
N
10
10
10
10
10
50
Mean
.8140
1.0030
1.1460
1.2080
1.3540
1.1050
Std.
Deviatio
n
.1229
.0933
.2060
.1321
.3117
.2604
Std.
Error
.0389
.0295
.0652
.0418
.0986
.0368
Test of Homogeneity of Variances
Waktu Larut 60
Levene
Statistic
6.824
df1
df2
4
45
Sig.
.000
95% Confidence
Interval for Mean
Lower
Upper
Bound
Bound
.7261
.9019
.9362
1.0698
.9986
1.2934
1.1135
1.3025
1.1310
1.5770
1.0310
1.1790
Minimum
.68
.90
.85
1.03
.95
.68
Maximum
1.08
1.20
1.53
1.45
1.82
1.82
65
ANOVA
Waktu Larut 60
Between Groups
Within Groups
Total
Sum of
Squares
1.694
1.628
3.321
df
4
45
49
Mean Square
.423
.036
F
11.707
Sig.
.000
Post Hoc Tests
Multiple Comparisons
Dependent Variable: Waktu Larut 60
Scheffe
(I) Perlakuan
Formula I
Formula II
Formula III
Formula IV
Formula V
(J) Perlakuan
Formula II
Formula III
Formula IV
Formula V
Formula I
Formula III
Formula IV
Formula V
Formula I
Formula II
Formula IV
Formula V
Formula I
Formula II
Formula III
Formula V
Formula I
Formula II
Formula III
Formula IV
Mean
Difference
(I-J)
-.1890
-.3320*
-.3940*
-.5400*
.1890
-.1430
-.2050
-.3510*
.3320*
.1430
-.0620
-.2080
.3940*
.2050
.0620
-.1460
.5400*
.3510*
.2080
.1460
Std. Error
.0851
.0851
.0851
.0851
.0851
.0851
.0851
.0851
.0851
.0851
.0851
.0851
.0851
.0851
.0851
.0851
.0851
.0851
.0851
.0851
*. The mean difference is significant at the .05 level.
Sig.
.310
.009
.001
.000
.310
.592
.233
.005
.009
.592
.970
.220
.001
.233
.970
.572
.000
.005
.220
.572
95% Confidence Interval
Lower Bound Upper Bound
-.4622
.0842
-.6052
-.0588
-.6672
-.1208
-.8132
-.2668
-.0842
.4622
-.4162
.1302
-.4782
.0682
-.6242
-.0778
.0588
.6052
-.1302
.4162
-.3352
.2112
-.4812
.0652
.1208
.6672
-.0682
.4782
-.2112
.3352
-.4192
.1272
.2668
.8132
.0778
.6242
-.0652
.4812
-.1272
.4192
66
Lampiran 1
Hasil pengukuran waktu alir granul
Replikasi
FI
9.51
8.96
8.27
8.91
0.62
1
2
3
Mean
SD
F II
9.18
8
8.37
8.52
0.60
Waktu alir (detik)
F III
8.43
8.17
8.51
8.37
0.18
F IV
7.23
8.09
8.12
7.81
0.505
FV
6.34
5.95
6.14
6.14
0.195
Oneway
Descriptives
Waktu Alir
N
Formula I
Formula II
Formula III
Formula IV
Formula V
Total
3
3
3
3
3
15
Mean
8.9133
8.5167
8.3700
7.8133
6.1433
7.9513
Std.
Deviation
.6213
.6035
.1778
.5054
.1950
1.0782
Std.
Error
.3587
.3484
.1026
.2918
.1126
.2784
Test of Homogeneity of Variances
Waktu Alir
Levene
Statistic
1.669
df1
df2
4
10
Sig.
.233
95% Confidence
Interval for Mean
Lower
Upper
Bound
Bound
7.3699
10.4568
7.0174
10.0159
7.9284
8.8116
6.5578
9.0688
5.6589
6.6278
7.3542
8.5484
Minimum
8.27
8.00
8.17
7.23
5.95
5.95
Maximum
9.51
9.18
8.51
8.12
6.34
9.51
46
ANOVA
Waktu Alir
Between Groups
Within Groups
Total
Sum of
Squares
14.125
2.151
16.275
df
4
10
14
Mean Square
3.531
.215
F
16.419
Sig.
.000
Post Hoc Tests
Multiple Comparisons
Dependent Variable: Waktu Alir
Scheffe
(I) Perlakuan
Formula I
Formula II
Formula III
Formula IV
Formula V
(J) Perlakuan
Formula II
Formula III
Formula IV
Formula V
Formula I
Formula III
Formula IV
Formula V
Formula I
Formula II
Formula IV
Formula V
Formula I
Formula II
Formula III
Formula V
Formula I
Formula II
Formula III
Formula IV
Mean
Difference
(I-J)
.3967
.5433
1.1000
2.7700*
-.3967
.1467
.7033
2.3733*
-.5433
-.1467
.5567
2.2267*
-1.1000
-.7033
-.5567
1.6700*
-2.7700*
-2.3733*
-2.2267*
-1.6700*
Std. Error
.3787
.3787
.3787
.3787
.3787
.3787
.3787
.3787
.3787
.3787
.3787
.3787
.3787
.3787
.3787
.3787
.3787
.3787
.3787
.3787
*. The mean difference is significant at the .05 level.
Sig.
.888
.727
.154
.001
.888
.997
.519
.002
.727
.997
.710
.003
.154
.519
.710
.019
.001
.002
.003
.019
95% Confidence Interval
Lower Bound Upper Bound
-1.0157
1.8090
-.8690
1.9557
-.3123
2.5123
1.3577
4.1823
-1.8090
1.0157
-1.2657
1.5590
-.7090
2.1157
.9610
3.7857
-1.9557
.8690
-1.5590
1.2657
-.8557
1.9690
.8143
3.6390
-2.5123
.3123
-2.1157
.7090
-1.9690
.8557
.2577
3.0823
-4.1823
-1.3577
-3.7857
-.9610
-3.6390
-.8143
-3.0823
-.2577
47
Lampiran 2
Hasil pengukuran sudut diam granul
Replikasi
FI
30.68
33.47
32.78
32.31
1.45
1
2
3
Mean
SD
Sudut diam (°)
F III
32.35
29.54
30.47
30.79
1.43
F II
31.3
31.56
31.3
31.39
0.15
F IV
31.5
29.45
30.61
30.52
1.03
FV
28.47
28.27
27.32
28.02
0.61
Oneway
Descriptives
Sudut Diam
N
Formula I
Formula II
Formula III
Formula IV
Formula V
Total
3
3
3
3
3
15
Mean
32.3100
31.3867
30.7867
30.5200
28.0200
30.6047
Std.
Deviation
1.4532
.1501
1.4315
1.0280
.6144
1.7312
Std.
Error
.8390
.0867
.8265
.5935
.3547
.4470
Test of Homogeneity of Variances
Sudut Diam
Levene
Statistic
2.241
df1
df2
4
10
Sig.
.137
95% Confidence
Interval for Mean
Lower
Upper
Bound
Bound
28.7001
35.9199
31.0138
31.7596
27.2306
34.3427
27.9664
33.0736
26.4937
29.5463
29.6460
31.5634
Minimum
30.68
31.30
29.54
29.45
27.32
27.32
Maximum
33.47
31.56
32.35
31.50
28.47
33.47
48
ANOVA
Sudut Diam
Between Groups
Within Groups
Total
Sum of
Squares
30.721
11.235
41.957
df
4
10
14
Mean Square
7.680
1.124
F
6.836
Sig.
.006
Post Hoc Tests
Multiple Comparisons
Dependent Variable: Sudut Diam
Scheffe
(I) Perlakuan
Formula I
Formula II
Formula III
Formula IV
Formula V
(J) Perlakuan
Formula II
Formula III
Formula IV
Formula V
Formula I
Formula III
Formula IV
Formula V
Formula I
Formula II
Formula IV
Formula V
Formula I
Formula II
Formula III
Formula V
Formula I
Formula II
Formula III
Formula IV
Mean
Difference
(I-J)
.9233
1.5233
1.7900
4.2900*
-.9233
.6000
.8667
3.3667*
-1.5233
-.6000
.2667
2.7667
-1.7900
-.8667
-.2667
2.5000
-4.2900*
-3.3667*
-2.7667
-2.5000
Std. Error
.8655
.8655
.8655
.8655
.8655
.8655
.8655
.8655
.8655
.8655
.8655
.8655
.8655
.8655
.8655
.8655
.8655
.8655
.8655
.8655
*. The mean difference is significant at the .05 level.
Sig.
.881
.566
.421
.009
.881
.972
.903
.040
.566
.972
.999
.104
.421
.903
.999
.158
.009
.040
.104
.158
95% Confidence Interval
Lower Bound Upper Bound
-2.3048
4.1514
-1.7048
4.7514
-1.4381
5.0181
1.0619
7.5181
-4.1514
2.3048
-2.6281
3.8281
-2.3614
4.0948
.1386
6.5948
-4.7514
1.7048
-3.8281
2.6281
-2.9614
3.4948
-.4614
5.9948
-5.0181
1.4381
-4.0948
2.3614
-3.4948
2.9614
-.7281
5.7281
-7.5181
-1.0619
-6.5948
-.1386
-5.9948
.4614
-5.7281
.7281
49
Lampiran 3
Hasil uji keseragaman bobot tablet
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
FI
2.98
2.97
2.97
3
2.94
2.95
2.89
2.98
2.99
3.01
2.98
2.97
2.88
2.9
2.97
3.01
2.98
3.02
2.96
2.99
F II
3
3.01
2.98
2.99
2.99
2.96
3
2.99
2.98
2.95
2.96
2.87
2.91
3.01
2.99
2.97
2.96
3.02
2.99
3
Bobot tablet (g)
F III
2.98
3.03
3.05
3
2.98
3
2.96
2.98
3
2.95
3.04
2.96
2.98
2.97
3.02
3.05
3.07
3.02
3
2.98
Mean
2.967
2.9765
3.001
2.999
3.003
SD
0.039
0.036
0.034
0.042
0.038
CV
1.30
1.195
1.13
1.39
1.28
Replikasi
F IV
3.02
3
3.05
2.99
2.89
3.02
2.99
2.96
2.97
3.05
2.99
3.07
3.03
3
3.03
2.98
3.02
3
2.99
2.93
FV
3.05
3
2.95
3.04
3.02
2.98
2.93
2.94
3.02
3.03
2.99
3.04
3.02
3
3.08
3.02
3
2.96
2.98
3.01
50
Perhitungan keseragaman bobot tablet menurut Farmakope Indonesia :
1. Formula I
Bobot rata-rata 20 tablet = 2,967 g
5
x Untuk penyimpangan 5% =
x 2,967 g 0,148 g
100
Jadi berat tablet = 2,967 g + 0,148 g (2,819 g – 3,115 g)
10
x Untuk penyimpangan 10% =
x 2,967 g 0,297 g
100
Jadi berat tablet = 2,967 g + 0,297 g (2,67 g – 3,264 g)
2. Formula II
Bobot rata-rata 20 tablet = 2,9765 g
5
x Untuk penyimpangan 5% =
x 2,97 65 g 0,149 g
100
Jadi berat tablet = 2,9765 g + 0,149 g (2,8275 g – 3,1255 g)
10
x Untuk penyimpangan 10% =
x 2,9765 g 0,298 g
100
Jadi berat tablet = 2,9765 g + 0,298 g (2,6785 g – 3,274 g)
3. Formula III
Bobot rata-rata 20 tablet = 3,001 g
5
x Untuk penyimpangan 5% =
x 3,001 g 0,15 g
100
Jadi berat tablet = 3,001 g + 0,15 g (2,851 g – 3,151 g)
10
x Untuk penyimpangan 10% =
x 3,001 g 0,30 g
100
Jadi berat tablet = 3,001 g + 0,30 g (2,701 g – 3,301 g)
4. Formula IV
Bobot rata-rata 20 tablet = 2,999 g
5
x Untuk penyimpangan 5% =
x 2,999 g 0,15 g
100
Jadi berat tablet = 2,999 g + 0,15 g (2,849 g – 3,149 g)
10
x Untuk penyimpangan 10% =
x 2,999 g 0,30 g
100
Jadi berat tablet = 2,999 g + 0,30 g (2,699 g – 3,299 g)
51
5. Formula V
Bobot rata-rata 20 tablet = 3,003 g
5
x Untuk penyimpangan 5% =
x 3,003 g 0,15 g
100
Jadi berat tablet = 3,003 g + 0,15 g (2,853 g – 3,153 g)
10
x Untuk penyimpangan 10% =
x 3,003 g 0,30 g
100
Jadi berat tablet = 3,003 g + 0,30 g (2,703 g – 3,303 g)
Oneway
Descriptives
Keseragaman Bobot
Formula I
Formula II
Formula III
Formula IV
Formula V
Total
N
20
20
20
20
20
100
Mean
2.9670
2.9765
3.0010
2.9990
3.0030
2.9893
Std.
Deviation
.03868
.03558
.03386
.04179
.03840
.03983
Std.
Error
.00865
.00796
.00757
.00934
.00859
.00398
95% Confidence
Interval for Mean
Lower
Upper
Bound
Bound
2.9489
2.9851
2.9598
2.9932
2.9852
3.0168
2.9794
3.0186
2.9850
3.0210
2.9814
2.9972
Minimum
2.88
2.87
2.95
2.89
2.93
2.87
Maximum
3.02
3.02
3.07
3.07
3.08
3.08
Test of Homogeneity of Variances
Keseragaman Bobot
Levene
Statistic
.126
df1
df2
4
Sig.
.973
95
ANOVA
Keseragaman Bobot
Between Groups
Within Groups
Total
Sum of
Squares
.022
.135
.157
df
4
95
99
Mean Square
.005
.001
F
3.787
Sig.
.007
52
Post Hoc Tests
Multiple Comparisons
Dependent Variable: Keseragaman Bobot
Scheffe
(I) Perlakuan
Formula I
Formula II
Formula III
Formula IV
Formula V
(J) Perlakuan
Formula II
Formula III
Formula IV
Formula V
Formula I
Formula III
Formula IV
Formula V
Formula I
Formula II
Formula IV
Formula V
Formula I
Formula II
Formula III
Formula V
Formula I
Formula II
Formula III
Formula IV
Mean
Difference
(I-J)
-.0095
-.0340
-.0320
-.0360
.0095
-.0245
-.0225
-.0265
.0340
.0245
.0020
-.0020
.0320
.0225
-.0020
-.0040
.0360
.0265
.0020
.0040
Std.
Error
.01194
.01194
.01194
.01194
.01194
.01194
.01194
.01194
.01194
.01194
.01194
.01194
.01194
.01194
.01194
.01194
.01194
.01194
.01194
.01194
Sig.
.959
.097
.136
.067
.959
.385
.475
.303
.097
.385
1.000
1.000
.136
.475
1.000
.998
.067
.303
1.000
.998
95% Confidence
Interval
Lower
Upper
Bound
Bound
-.0470
.0280
-.0715
.0035
-.0695
.0055
-.0735
.0015
-.0280
.0470
-.0620
.0130
-.0600
.0150
-.0640
.0110
-.0035
.0715
-.0130
.0620
-.0355
.0395
-.0395
.0355
-.0055
.0695
-.0150
.0600
-.0395
.0355
-.0415
.0335
-.0015
.0735
-.0110
.0640
-.0355
.0395
-.0335
.0415
53
Lampiran 4
Hasil uji kekerasan tablet
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
FI
5.35
5.38
5.23
5.09
5.05
4.74
4.84
5.26
6.51
4.47
5.93
4.08
4.86
5.22
6.12
5.48
6.03
4.83
4.84
6.07
Kekerasan tablet (kg)
F II
F III
F IV
6.25
7.84
7.34
6.31
6.34
7.06
5.3
6.13
6.69
6.3
5.6
7.65
5.55
5.91
7.42
5.95
5.53
7.13
6.76
5.09
6.85
7.14
6.81
7.11
6.14
7.49
5.96
6.27
7.71
6.97
6.06
6.18
6.77
7.69
7.86
6.57
6.3
6.96
6.72
5.87
7.38
6.47
6.6
6.46
6.27
7.61
6.44
6.61
6.58
5.31
7.54
6.65
6.11
7.47
6.01
6.63
7.35
6.55
5.87
7.65
FV
6.29
7.47
7.67
7.66
6.77
6.96
7.43
6.55
7.49
6.86
7.38
6.35
7.47
6.81
7.85
7.39
6.05
7.03
6.96
7.42
Mean
5.27
6.39
6.48
6.98
7.09
SD
0.61
0.65
0.84
0.47
0.51
Replikasi
54
Oneway
Descriptives
Kekerasan Tablet
Formula I
Formula II
Formula III
Formula IV
Formula V
Total
N
20
20
20
20
20
100
Std.
Deviation
.6126
.5974
.8431
.4746
.5088
.8903
Mean
5.2690
6.3945
6.4825
6.9800
7.0930
6.4438
Std.
Error
.1370
.1336
.1885
.1061
.1138
.0890
95% Confidence
Interval for Mean
Lower
Upper
Bound
Bound
4.9823
5.5557
6.1149
6.6741
6.0879
6.8771
6.7579
7.2021
6.8549
7.3311
6.2671
6.6205
Minimum
4.08
5.30
5.09
5.96
6.05
4.08
Maximum
6.51
7.69
7.86
7.65
7.85
7.86
Test of Homogeneity of Variances
Kekerasan Tablet
Levene
Statistic
2.047
df1
df2
4
Sig.
.094
95
ANOVA
Kekerasan Tablet
Between Groups
Within Groups
Total
Sum of
Squares
41.861
36.613
78.474
df
4
95
99
Mean Square
10.465
.385
F
27.155
Sig.
.000
55
Post Hoc Tests
Multiple Comparisons
Dependent Variable: Kekerasan Tablet
Scheffe
(I) Perlakuan
Formula I
Formula II
Formula III
Formula IV
Formula V
(J) Perlakuan
Formula II
Formula III
Formula IV
Formula V
Formula I
Formula III
Formula IV
Formula V
Formula I
Formula II
Formula IV
Formula V
Formula I
Formula II
Formula III
Formula V
Formula I
Formula II
Formula III
Formula IV
Mean
Difference
(I-J)
-1.1255*
-1.2135*
-1.7110*
-1.8240*
1.1255*
-.0880
-.5855
-.6985*
1.2135*
.0880
-.4975
-.6105
1.7110*
.5855
.4975
-.1130
1.8240*
.6985*
.6105
.1130
95% Confidence Interval
Std. Error
.1963
.1963
.1963
.1963
.1963
.1963
.1963
.1963
.1963
.1963
.1963
.1963
.1963
.1963
.1963
.1963
.1963
.1963
.1963
.1963
*. The mean difference is significant at the .05 level.
Sig.
.000
.000
.000
.000
.000
.995
.072
.017
.000
.995
.179
.054
.000
.072
.179
.988
.000
.017
.054
.988
Lower Bound
-1.7423
-1.8303
-2.3278
-2.4408
.5087
-.7048
-1.2023
-1.3153
.5967
-.5288
-1.1143
-1.2273
1.0942
-.0313
-.1193
-.7298
1.2072
.0817
-.0063
-.5038
Upper Bound
-.5087
-.5967
-1.0942
-1.2072
1.7423
.5288
.0313
-.0817
1.8303
.7048
.1193
.0063
2.3278
1.2023
1.1143
.5038
2.4408
1.3153
1.2273
.7298
56
Lampiran 5
Hasil uji kerapuhan tablet
Kerapuhan tablet (%)
F II
F III
F IV
0.202
0.151
0.117
0.219
0.219
0.201
0.422
0.253
0.285
Replikasi
1
2
3
FI
0.253
0.355
0.304
FV
0.117
0.218
0.167
Mean
0.30
0.28
0.22
0.20
0.17
SD
0.05
0.12
0.05
0.08
0.05
Oneway
Descriptives
Kerapuhan Tablet
N
Formula I
Formula II
Formula III
Formula IV
Formula V
Total
3
3
3
3
3
15
Mean
.3040
.2810
.2077
.2010
.1673
.2322
Std.
Deviation
.0510
.1224
.0519
.0840
.0505
.0844
Std.
Error
.0294
.0707
.0300
.0485
.0292
.0218
Test of Homogeneity of Variances
Kerapuhan Tablet
Levene
Statistic
1.557
df1
df2
4
10
Sig.
.259
95% Confidence
Interval for Mean
Lower
Upper
Bound
Bound
.1773
.4307
-.0231
.5851
.0787
.3367
-.0077
.4097
.0419
.2928
.1855
.2789
Minimum
.25
.20
.15
.12
.12
.12
Maximum
.36
.42
.25
.28
.22
.42
57
ANOVA
Kerapuhan Tablet
Between Groups
Within Groups
Total
Sum of
Squares
.040
.060
.100
df
4
10
14
Mean Square
.010
.006
F
1.671
Sig.
.232
Lampiran 6
Hasil uji waktu larut tablet
a. Suhu 10°C
Replikasi
Waktu larut (menit)
F III
F IV
8.58
8.9
8.83
9.17
9.2
8.47
7.67
8.27
9.75
8.37
9.92
10.22
7.5
9.35
8.25
9.55
9.92
9.25
9.97
10.68
1
2
3
4
5
6
7
8
9
10
FI
3.48
3.63
2.63
2.55
3.01
3.48
4.23
4.02
3.03
4.05
F II
6.77
6.68
7.92
6.6
7.25
7.82
8.2
8.42
8.53
8.58
FV
8.22
8.07
9.42
8.1
10.02
9.15
11.22
10.13
11.77
11.3
Mean
3.41
7.68
8.96
9.22
9.74
SD
0.59
0.79
0.94
0.785
1.38
58
Oneway
Descriptives
Waktu Larut 10
Formula I
Formula II
Formula III
Formula IV
Formula V
Total
N
10
10
10
10
10
50
Mean
3.4110
7.6770
8.9590
9.2230
9.7400
7.8020
Std.
Deviation
.5930
.7893
.9432
.7853
1.3830
2.4893
Std.
Error
.1875
.2496
.2983
.2483
.4374
.3520
Test of Homogeneity of Variances
Waktu Larut 10
Levene
Statistic
3.050
df1
df2
4
45
Sig.
.026
95% Confidence
Interval for Mean
Lower
Upper
Bound
Bound
2.9868
3.8352
7.1124
8.2416
8.2843
9.6337
8.6612
9.7848
8.7506
10.7294
7.0945
8.5095
Minimum
2.55
6.60
7.50
8.27
8.07
2.55
Maximum
4.23
8.58
9.97
10.68
11.77
11.77
59
Post Hoc Tests
Multiple Comparisons
Dependent Variable: Waktu Larut 10
Scheffe
(I) Perlakuan
Formula I
Formula II
Formula III
Formula IV
Formula V
(J) Perlakuan
Formula II
Formula III
Formula IV
Formula V
Formula I
Formula III
Formula IV
Formula V
Formula I
Formula II
Formula IV
Formula V
Formula I
Formula II
Formula III
Formula V
Formula I
Formula II
Formula III
Formula IV
Mean
Difference
(I-J)
-4.2660*
-5.5480*
-5.8120*
-6.3290*
4.2660*
-1.2820
-1.5460*
-2.0630*
5.5480*
1.2820
-.2640
-.7810
5.8120*
1.5460*
.2640
-.5170
6.3290*
2.0630*
.7810
.5170
Std. Error
.4192
.4192
.4192
.4192
.4192
.4192
.4192
.4192
.4192
.4192
.4192
.4192
.4192
.4192
.4192
.4192
.4192
.4192
.4192
.4192
*. The mean difference is significant at the .05 level.
Sig.
.000
.000
.000
.000
.000
.070
.016
.001
.000
.070
.982
.491
.000
.016
.982
.822
.000
.001
.491
.822
95% Confidence Interval
Lower Bound Upper Bound
-5.6124
-2.9196
-6.8944
-4.2016
-7.1584
-4.4656
-7.6754
-4.9826
2.9196
5.6124
-2.6284
.0644
-2.8924
-.1996
-3.4094
-.7166
4.2016
6.8944
-.0644
2.6284
-1.6104
1.0824
-2.1274
.5654
4.4656
7.1584
.1996
2.8924
-1.0824
1.6104
-1.8634
.8294
4.9826
7.6754
.7166
3.4094
-.5654
2.1274
-.8294
1.8634
60
b. Suhu 25°C
Replikasi
Waktu larut (menit)
1
2
3
4
5
6
7
8
9
10
FI
2.01
2.02
2.03
2.82
1.52
2.5
1.95
2.12
1.45
1.8
F II
3.03
3.04
3.5
3.23
3.37
3.62
3.5
3.75
3.78
4.15
F III
3.06
3.5
4.15
3.75
5.25
4.15
4.37
4.62
5.58
5.65
F IV
5.12
5.15
5.23
4.83
4.36
5.68
5.65
4.98
5.77
5.4
FV
4.25
5.25
5.47
5.03
5.38
5.65
5.95
5.37
5.42
5.52
2.02
3.50
4.41
5.21
5.33
0.41
0.35
0.87
0.43
0.45
Mean
SD
Oneway
Descriptives
Waktu Larut 25
N
Formula I
Formula II
Formula III
Formula IV
Formula V
Total
10
10
10
10
10
50
Mean
2.0220
3.4970
4.4080
5.2170
5.3290
4.0946
Std.
Deviation
.4094
.3496
.8743
.4341
.4494
1.3428
Std.
Error
.1295
.1106
.2765
.1373
.1421
.1899
Test of Homogeneity of Variances
Waktu Larut 25
Levene
Statistic
3.109
df1
df2
4
45
Sig.
.024
95% Confidence
Interval for Mean
Lower
Upper
Bound
Bound
1.7291
2.3149
3.2469
3.7471
3.7826
5.0334
4.9065
5.5275
5.0075
5.6505
3.7130
4.4762
Minimum
1.45
3.03
3.06
4.36
4.25
1.45
Maximum
2.82
4.15
5.65
5.77
5.95
5.95
61
ANOVA
Waktu Larut 25
Between Groups
Within Groups
Total
Sum of
Squares
75.345
13.001
88.346
df
4
45
49
Mean Square
18.836
.289
F
65.198
Sig.
.000
Post Hoc Tests
Multiple Comparisons
Dependent Variable: Waktu Larut 25
Scheffe
(I) Perlakuan
Formula I
Formula II
Formula III
Formula IV
Formula V
(J) Perlakuan
Formula II
Formula III
Formula IV
Formula V
Formula I
Formula III
Formula IV
Formula V
Formula I
Formula II
Formula IV
Formula V
Formula I
Formula II
Formula III
Formula V
Formula I
Formula II
Formula III
Formula IV
Mean
Difference
(I-J)
-1.4750*
-2.3860*
-3.1950*
-3.3070*
1.4750*
-.9110*
-1.7200*
-1.8320*
2.3860*
.9110*
-.8090*
-.9210*
3.1950*
1.7200*
.8090*
-.1120
3.3070*
1.8320*
.9210*
.1120
Std. Error
.2404
.2404
.2404
.2404
.2404
.2404
.2404
.2404
.2404
.2404
.2404
.2404
.2404
.2404
.2404
.2404
.2404
.2404
.2404
.2404
*. The mean difference is significant at the .05 level.
Sig.
.000
.000
.000
.000
.000
.013
.000
.000
.000
.013
.035
.011
.000
.000
.035
.994
.000
.000
.011
.994
95% Confidence Interval
Lower Bound Upper Bound
-2.2470
-.7030
-3.1580
-1.6140
-3.9670
-2.4230
-4.0790
-2.5350
.7030
2.2470
-1.6830
-.1390
-2.4920
-.9480
-2.6040
-1.0600
1.6140
3.1580
.1390
1.6830
-1.5810
-.0370
-1.6930
-.1490
2.4230
3.9670
.9480
2.4920
.0370
1.5810
-.8840
.6600
2.5350
4.0790
1.0600
2.6040
.1490
1.6930
-.6600
.8840
62
c. Suhu 35°C
Replikasi
1
2
3
4
5
6
7
8
9
10
FI
1.15
0.98
1.18
1.53
0.85
0.98
1.42
1.08
1.15
1.22
F II
1.97
1.27
1.12
1.33
1.05
1.18
1.32
1.03
1.27
1.3
Waktu larut (menit)
F III
2.75
2.23
2.43
2.5
2.03
2.07
2.05
2.55
2.9
2.58
1.15
1.28
2.41
3.13
3.42
0.20
0.26
0.30
0.66
0.36
Mean
SD
F IV
2.37
3.38
3.85
3.92
2.23
2.83
2.25
3.5
3.58
3.43
FV
3.05
3.27
3.35
3.85
3.97
3.37
3.22
3.08
3.92
3.08
Oneway
Descriptives
Waktu Larut 35
N
Formula I
Formula II
Formula III
Formula IV
Formula V
Total
10
10
10
10
10
50
Mean
1.1540
1.2840
2.4090
3.1340
3.4160
2.2794
Std.
Deviation
.2043
.2649
.3045
.6571
.3614
1.0088
Std.
Error
.0646
.0838
.0963
.2078
.1143
.1427
Test of Homogeneity of Variances
Waktu Larut 35
Levene
Statistic
8.059
df1
df2
4
45
Sig.
.000
95% Confidence
Interval for Mean
Lower
Upper
Bound
Bound
1.0079
1.3001
1.0945
1.4735
2.1911
2.6269
2.6639
3.6041
3.1575
3.6745
1.9927
2.5661
Minimum
.85
1.03
2.03
2.23
3.05
.85
Maximum
1.53
1.97
2.90
3.92
3.97
3.97
63
ANOVA
Waktu Larut 35
Between Groups
Within Groups
Total
Sum of
Squares
42.963
6.903
49.867
df
4
45
49
Mean Square
10.741
.153
F
70.014
Sig.
.000
Post Hoc Tests
Multiple Comparisons
Dependent Variable: Waktu Larut 35
Scheffe
(I) Perlakuan
Formula I
Formula II
Formula III
Formula IV
Formula V
(J) Perlakuan
Formula II
Formula III
Formula IV
Formula V
Formula I
Formula III
Formula IV
Formula V
Formula I
Formula II
Formula IV
Formula V
Formula I
Formula II
Formula III
Formula V
Formula I
Formula II
Formula III
Formula IV
Mean
Difference
(I-J)
-.1300
-1.2550*
-1.9800*
-2.2620*
.1300
-1.1250*
-1.8500*
-2.1320*
1.2550*
1.1250*
-.7250*
-1.0070*
1.9800*
1.8500*
.7250*
-.2820
2.2620*
2.1320*
1.0070*
.2820
Std. Error
.1752
.1752
.1752
.1752
.1752
.1752
.1752
.1752
.1752
.1752
.1752
.1752
.1752
.1752
.1752
.1752
.1752
.1752
.1752
.1752
*. The mean difference is significant at the .05 level.
Sig.
.967
.000
.000
.000
.967
.000
.000
.000
.000
.000
.005
.000
.000
.000
.005
.631
.000
.000
.000
.631
95% Confidence Interval
Lower Bound Upper Bound
-.6926
.4326
-1.8176
-.6924
-2.5426
-1.4174
-2.8246
-1.6994
-.4326
.6926
-1.6876
-.5624
-2.4126
-1.2874
-2.6946
-1.5694
.6924
1.8176
.5624
1.6876
-1.2876
-.1624
-1.5696
-.4444
1.4174
2.5426
1.2874
2.4126
.1624
1.2876
-.8446
.2806
1.6994
2.8246
1.5694
2.6946
.4444
1.5696
-.2806
.8446
64
d. Suhu 60°C
Replikasi
1
2
3
4
5
6
7
8
9
10
FI
1.08
0.95
0.72
0.8
0.82
0.83
0.68
0.8
0.68
0.78
F II
0.98
1
0.9
0.95
1.02
1.13
0.95
1.2
0.97
0.93
Waktu larut (menit)
F III
1.07
0.98
1.18
1.53
0.85
0.98
1.42
1.08
1.15
1.22
0.81
1.00
1.15
1.21
1.35
0.12
0.09
0.21
0.13
0.31
Mean
SD
F IV
1.45
1.13
1.22
1.13
1.1
1.18
1.4
1.17
1.27
1.03
FV
1.02
1.2
1.55
1.82
1.67
1.02
1.43
0.95
1.23
1.65
Oneway
Descriptives
Waktu Larut 60
Formula I
Formula II
Formula III
Formula IV
Formula V
Total
N
10
10
10
10
10
50
Mean
.8140
1.0030
1.1460
1.2080
1.3540
1.1050
Std.
Deviatio
n
.1229
.0933
.2060
.1321
.3117
.2604
Std.
Error
.0389
.0295
.0652
.0418
.0986
.0368
Test of Homogeneity of Variances
Waktu Larut 60
Levene
Statistic
6.824
df1
df2
4
45
Sig.
.000
95% Confidence
Interval for Mean
Lower
Upper
Bound
Bound
.7261
.9019
.9362
1.0698
.9986
1.2934
1.1135
1.3025
1.1310
1.5770
1.0310
1.1790
Minimum
.68
.90
.85
1.03
.95
.68
Maximum
1.08
1.20
1.53
1.45
1.82
1.82
65
ANOVA
Waktu Larut 60
Between Groups
Within Groups
Total
Sum of
Squares
1.694
1.628
3.321
df
4
45
49
Mean Square
.423
.036
F
11.707
Sig.
.000
Post Hoc Tests
Multiple Comparisons
Dependent Variable: Waktu Larut 60
Scheffe
(I) Perlakuan
Formula I
Formula II
Formula III
Formula IV
Formula V
(J) Perlakuan
Formula II
Formula III
Formula IV
Formula V
Formula I
Formula III
Formula IV
Formula V
Formula I
Formula II
Formula IV
Formula V
Formula I
Formula II
Formula III
Formula V
Formula I
Formula II
Formula III
Formula IV
Mean
Difference
(I-J)
-.1890
-.3320*
-.3940*
-.5400*
.1890
-.1430
-.2050
-.3510*
.3320*
.1430
-.0620
-.2080
.3940*
.2050
.0620
-.1460
.5400*
.3510*
.2080
.1460
Std. Error
.0851
.0851
.0851
.0851
.0851
.0851
.0851
.0851
.0851
.0851
.0851
.0851
.0851
.0851
.0851
.0851
.0851
.0851
.0851
.0851
*. The mean difference is significant at the .05 level.
Sig.
.310
.009
.001
.000
.310
.592
.233
.005
.009
.592
.970
.220
.001
.233
.970
.572
.000
.005
.220
.572
95% Confidence Interval
Lower Bound Upper Bound
-.4622
.0842
-.6052
-.0588
-.6672
-.1208
-.8132
-.2668
-.0842
.4622
-.4162
.1302
-.4782
.0682
-.6242
-.0778
.0588
.6052
-.1302
.4162
-.3352
.2112
-.4812
.0652
.1208
.6672
-.0682
.4782
-.2112
.3352
-.4192
.1272
.2668
.8132
.0778
.6242
-.0652
.4812
-.1272
.4192
66