839.11i 71,7j - Pengaruh beberapa kombinasi antioksidan sodium metabisulfit dan askorbil palmitat terhadap stabilitas kadar ketokonazol dalam sediaan suspensi - Widya Mandala Catholic University Surabaya Repository

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db

RJK

F h i t u n q F(0,05)

F(0,01\

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Ey

Py
Ey

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108,91 12,10111 11,09407
58,70 19,56666
47,62 1,763703

3
27

2,96

4,60

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TOTAL

39

db (TOTAL) = kn
db (Py)
= Ik
= In
db (By)

215,23

-

1
1)
1)

-

-

db (Ey) = db (TOTAL - Py - By 1
RJK
= J K Idb
F h i t u n g = RJKlPyI / RJK(Ey)

Y r i t e r i a pengujian :
t B i l a F h i t . ) F10,05) r a k a berbeda ~ i g n i f i k a n .
I B i l a F h i t . ) F(0,Ol) r a k a berbeda sangat s i g n i f i k a n .

Pengujlan hlpotesa

;

a . H : P1.O
B e r a r t i t l d a k ada perbedaan EFEK yang s l q n l f l k a n
sebagal a k i b a t perbedaan perlakuan.

h . KESlBPULAW :
Karena f h i t u n q ) F(0,011, r a k a H d i t o l a k dengan sangat
s i g n i f i k a n . Dengan perkataan l a i n perlakuan-perlakuan
rebberikan EFEK yang berbeda sangat s i g n i f i k a n .

,

--__-__----------------------------------------------......................................................
PEHLAKUAH

:

PERBEDAAN

HSO (511

KESIHPULAN

I HEAN
-------------'---------------------------------------F 1 vs F2
F1 vs f3

I

2
2,75
3,14
0'75

1,62

SIGNIFIKAN
SI6NIFIKAN
1,62
SI6NlFIKAN
Ft v s FI
llh2 TIDAY SIGNIFIKAN
F2 vs F3
l,l4
1862 TIDAK SIGNIFIKfiN
F2 ws F 4 :
1,62 TIDAK SIGNIF1 IN
F3 vs F 4 : 0,39
----------------------------------------*.
--n l = 10
Fl = 96,18
F Z = 98,18
02 = 10
F!, = 98'93
n3 = 10
F4 = 99,32
04 = 10

:
:
:

db

= 27

RJK = 1,76

l,b2

q = 3,87
p G 4

HASIL PERHITUNGAN STATIST1 K ANAVA ACAK SEMPURNA
DENGAN UJI HSD ( 5 % ) (PENENTUAN k)
'

1rit8r:a ?sogullan:

- 5,ia i hit,! F(G.d>\ s a k ~mrheoa 5 i ~ r ~ : i l k a n .
- b:ii F nit,: F ( 3 . L l l i eaka o e r L ~ d a sdnyat ~ l g i ~ l i i n a r , .

HASIL PERHITUNGAN STATISTIK ANAVA ACAK SEMPURNA
DENGAN UJI HSD ( 5 % ) (PENENTUAN tgO%)

I
---------------------------------------.----------------4
:
Jt
J I:
5Jd
i hit. i(0.051 i(3.31)

---------------------------------------------------------------------F/

1

2

ii

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~ r ~ t e r Fl i ~ i
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:a,iyjd.?990 85FBj.i997
3179,9120 397.4893

22A.381

4,07

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ii3.b:i

e i r a L ~ f b ~ dslqilfikan.
i

- E l i a F nit., F ( a . u l ) raKs t e r t r d a r i n g a t

hIPiTESk
----------FExibJIGh

slgnlf lkan.

:

i . x ; F 1 = G
i a n g t e r i r l [ i d i n iida pertiediian EFEC y i n g flgi~lfl~itii

sibigal

d ~ i tii p

~ r t ~ c a aperladban,
a

7.55

LAMPIRAN V I
DAFTAR NILAI r TABEL a = 5 % DAN a = 1 %

-

--

DEGREES OF
DEGREES OF
5
5
1
FREEDOM (DF) PtRCENT PERCENT FREEDOM (DF) PERCENT

-

I

.997

2
3
4

.950
,878
.8I 1
.754
.707

1 .OOO
.990
.959
.917
,874
,834

,666

.798

,632
.602
.576
.553
,532
.514
,497
,482
.468
,456
.444
,433
.423
.413
,404
.396

,765
,735
.708
,684
.661
.641
,623
.606
.590
.575
361
,549
.537
,526
.515

5

6
7
8
9
10

II
I2
13

I4

---

I5
16
17
18
19
20
21
22
23

.
.
.

.595

24
25
26
27
28
29
30
35
40
48
50
60
70
80
90
100
125
150
200
300
400
500
1000

.388
.381
,374
367
361
,355,
349
.325
,304
,288
.273
.250
.232
,217
.205
,195

.I74
.I59
.I38
.I 13
,098
.088
.062

..____--

1
FtRCENT

,496
.48/
,478
,470
,463
.456
A49
.418
,393
,372
,354
,325
,302
,283
,267
,254
.22B
,208
,181
. I40
.I28
.1 15
.081

C__

--

LAMPIRAN V I I
DAFTAR NILAI D I S T R I B U S I F ( p

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5
6
7
8
9
10
11
12
13
I4
15
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17
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19
20
24
30
4C
60
120

2

3

18.0
6.09
4.50
333
3.61
3.46
334
3.26
3.20
3.15
3.11
3.08
3.06
343
.J.DI
3.00
298
237
2.96
2.95
,292
2.89
2.86
2.83
2.80
2.77

26.7
k28
5.88
5.00
4.54
4.34
4.16
404
395
3.88
3.02
3.77
3.73
3.70
3.67
3.61
3.62
3.61
3.59
358
3.53
3.48
3.44
3.r0
336
332

4

5

37.2
32.8
9.80 10.89
6.83 7.51
6.31
5.76
5.64
5.18
4.90 5.31
4.68 5.06
4.53 4.89
442 4.76
4.33 4.66
416 4.58
4 2 0 4.51
4.15 4.46
4.11 4.11
4.08
431
4.05
434
4.02
4.31
4.00
428
3 3 8 426
3.36
46.24
3 9 0 4.17
3.84 4.11
3.79
4.04
3.74
338
3.69
332
3.63 3.06

P

6
40.5

11.73
8.04
6.73
5.99
5.63
5.35
5.17
5.02
4.91
4.82
4.75
4.69
4.66
.4.59
4.56
4.52
4.49
4.47
4.45
437
4.30
423
4.16
4.10
4.03

- 7

M

-11--12-'13

43.1
45.4 47.3 . a 9 1
86
519
12.43 12.03 13.54 13%
U.39
14.75
9.18 9.46
8 4 7 9.85
1.72
9.95
7.06
7.35 7.60
763
1.03
8.21
6 1 8 6.52
6.74 633
7.10
7.25
5.89 6.12
6.32 L49
6.65
6.79
5.59
5.80 5.99
629
E15
6.42
'5.40 - 5 . 6 0 5.77 192
L05
6.18
5.24
5.43 5.60 5.74
La7
5.98
5.12 5.30
5.46 5.60
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5.83
5.35 5.49
5.03 5.20
L61
5.71
4 3 5 5.12 5.27
5.40
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5.61
5.19
4.88
5.05
UZ ,543
5.53
4.83 4 9 9 5.13 1 2 5
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5.46
4.8
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5.08 sm
511
5.4a
4.14 4.90
5.03
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5.35
4.70
4.86
439
5.21
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4.67 4.03 4 9 6
5.17
517
4.64
4.79 432
LI4
5.23
4.62
4.17 4 3 0 5B1 LI1
510
432
$01
5.10
4.54
4.68 4.81
4.46
4.60
4.72
492 -5.M
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430
4.39
4 5 2 4.63 4.7'
4.31
4.44 4.55 4.65
473
4.81
4.71
4.24 4 3 6 4.47 4 s 4
4.17 4.29 4.39
4.55
4.62
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Enhr t fumimrn~ai&scar:

9

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in the k w n of @mumaw.

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10.16
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692
6.54
629
6.09
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5.81
5.71
5.63
5.56
5.49
544
5.39
5.35
5.32
528
5.18
5.08
4.98
4.88
4.78

1538
10.35
8.52
752
7.04
6.65
6.39
6.19
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530
530
5.71
5 .
5.57
5.52
547
5.43
519
536
525
5.15
505
434
434
4.74

4.68

IS
55.1
15.65
10.52
8.67
7.64
7.14
6.75
6.48
6.28
6.12
538
5.88
5.79
5.72
5.65
5.59
555
5.50
5.46
5.43
5.n
521
5.11
5.00
430
4.80

I

16
56.3
1531
10.69
8.80
7.75
7.24
6.84
6.57
6.36
620
6.06
595
5.86
5.79
5.72
5.66
5.61
5.57
5.53
5.50.
538
527
5.17
5.06
425
4.84

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IC.t4
18.M

580 58.8
1636 1657
10.98 11.12
Ut 9.03 9.14
7J6
795 8.04
1.34 7.43
7.51
U 3 701 ID8
ilbS 6.73 6.80
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6.51 6.58
UZ 6 3 4 f 4 1
La) 6.20 207
t02 609
IS
533
6.OC 6.06
5dC 532 5 3 8
m 5.85 531
533 5 . n 5 H
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5.74 1 7 9
5J3 5.m 5.74
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5%
5.61 5.56
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522 5 1 7 5 3 2
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5.11 5.15
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5.04

5.09

59.6
16.77
1124
9.24
8.13
7.59
7.16
6.87
6.65
6.47
6.33
621
Ell
6.03
536
530
5.04
5.79
5.75
5.71
5.59
5.48
5.36
5.24
5.13

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433

437

5.01

LAMPIRAN I X
SERTIFIKAT ANALISIS KETOKONAZOL

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