Uji Efek Antihiperurisemia Ekstrak Etanol Daun Pegagan (Centella asiatica (L.) Urb.) Pada Mencit Jantan
DAFTAR PUSTAKA
Abdulla, M.A., AL-Bayaty, F.H., Younis L.T., and Abu H.M.I. (2010). Anti-ulcer
activity of Centella asiatica leaf extract against ethanol-induced gastric
mucosal injury in rats. Journal of Medicinal Plants Research. 4(13): 12531259.
Babykutty, S., Padikkala, J., Sathiadevan, P.P., Vijayakurup, V., Azis TKA.,
Srinivas, P., Gopala, S. (2009). Apoptosis induction of Centella asiatica on
human breast cancer cells. African J. Trad. Compliment Alternat, Med. 6(1):
9-16.
Bourne, R.H., dan Zastrow, V.M. (2001). Reseptor dan Farmakodinamika Obat.
Dalam Farmakologi Dasar dan Klinik. Edisi I. Jakarta: Salemba Medika.
BPOM RI. (2010). Serial Data Ilmiah Terkini Tumbuhan Obat; Pegagan (Centella
asiatica (L.) Urban). Jakarta: Direktorat Obat Asli Indonesia
Bradwejn, J., Zhou, Y., Koszycki, D.,Shlik, J. (2000). A double blind, placebocontrolled study on the effects of gotu kola (Centella asiatica) on acoustic
startle response in healthy subject. J.Clin Psychopharmacol. 20(6): 680.
Cesarone, M.R., Incandela, L., De Sanctis, M.T., Belcaro, G., Bavera, P., Bucci,
M., Ippolito, E. (2001). Evaluation of treatment of diabetic microangiopathy
with total triterpenic fraction of Centella asiatica: A clinical prospective
randomized trial with a microcirculatory model. Angiol. 52(2): 49-54.
Depkes RI. (1977). Materia Medika Indonesia . Jilid I. Jakarta: Departemen
Kesehatan RI.
Depkes RI. (1995). Materia Medika Indonesia . Jilid VI. Jakarta: Departemen
Kesehatan Republik Indonesia.
Depkes RI. (2000). Parameter Standar Umum Ekstrak Tumbuhan Obat. Jakarta:
Departemen Kesehatan.
Ditjen POM. (1979). Farmakope Indonesia . Edisi III. Jakarta: Departemen
Kesehatan Republik Indonesia.
Ditjen POM. (1995). Farmakope Indonesia . Edisi IV. Jakarta: Departemen
Kesehatan Republik Indonesia.
Ernest, M.E., Clark, E.C. dan Hawkins, D.W. (2008). Dalam: Dipiro, J.T., Talbert,
R.L., Yee, G.C., Matzke, G.R., Wells, B.G., dan Posey, L.M.
Pharmacoteraphy; A pathophysiologic Approach. Seventh edition (2008).
USA: The McGraw-Hill Companies.
35
Universitas Sumatera Utara
Farnsworth, N.R. (1966). Biological and Phytochemical Screening of Plants.
Journal of Pharmaceutical Sciences.
Gaw, A., Murphy, M.J. Robert, O’reilly, C.D., Stewart, M.J. dan Stepherd, J.
(2011). Biokimia Klinis: Teks Bergambar. Edisi ke-4. Diterjemahkan oleh:
dr.Albertus Agung Mahode dan July Manurung. Jakarta: EGC.
Gnanappragasama, A., Ebenezar, K.K., Sathish, V., Govindarajub, P., Devaki, T.
(2004). Protective effect of Centella asiatica on antioxidant tissue defense
system against adriamycin induced cardiomyopathy in rats. Life Sciences.
76(2): 585-597.
Gnanapragasama, A., Yogeeta, S., Subhashini, R., Ebenezar, K.K., Sathish, V.,
Devaki, T. (2007). Adriamycin induced myocardial failure in rats:
Protective role of Centella asiatica. Molecular and Cellular Biochemistry.
294(1): 55-63.
Harborne, J.B. (1987). Metode Fitokimia Penuntun Cara Modern Menganalisis
Tumbuhan. Penerjemah : Kokasih Padmawinata dan Iwang Soediro. Edisi
Ketiga. Bandung: ITB Press
Hidayat, R. (2009). Gout dan Hiperurisemia. Scientific Journal Of Pharmaceutical
Development and Medical Application. 22(1): 47-50.
Incandela, L., Cesarone, M.R., Cacchio, M., De Sanctis, M.T., Santavenere, C.,
D’Auro, M.G., Bucci, M., Belcaro, G. (2001). Total triterpenic fraction of
Centella asiatica in chronic venous insufiency and high-perfussion
microangiopathy. Angiol. 52(2): 13-15.
Jayanthirtha, M. (2004). Preliminary immunodulatory activities of methanol extract
of Elipta alba and Centella asiatica. Phytomed. 11(4): 361-365.
Jayshree, G., Kurup, M.G., Sudars, W.S., Jacob, V.B. (2003). Anti-oxidant activity
of Centella asiatica on lymphoma-bearing mice. Fitoterapia . 74(5): 431434.
Katzung, B.G. (2002). Farmakologi: Dasar dan Klinik. Jilid 3. Diterjemahkan
oleh: Bagian Farmakologi Fakultas Kedokteran UNAIR. Jakarta: Salemba
Medika
Kristiani, R.D., Rahayu, D. dan Subarnas, A. (2013). Aktivitas Antihiperurisemia
Ekstrak Etanol Akar Pakis Tangkur (Polypodium feei) Pada Mencit Jantan.
Bionatura-Jurnal Ilmu-Ilmu Hayati dan Fisik. ISSN 1411-0903. 15(3): 174177.
Kumar, A., Dogra, S., Prakash, A. (2009). Neuroprotective effects of Centella
asiatica against intracerebroventricular colchicines-induced cognitive
impairment and oxidative stress. Intern J. Alzaimer’s Dis. 23(4): 25-28.
36
Universitas Sumatera Utara
Laurance, B., Keith, P., Donald, B., dan Lain, B. (2008). Goodman and Gildman’s
Manual of Farmacology and Therapeutics. Boston: McGraw Hill.
Li, H., Gong, X., Zhang, L., Zhang, Z., Lu, F., Zhou, Q., Chen, J., Wan, J. (2009).
Madecassoside attenuate inflammatory response on collagen-induced
arthritis in DBA/1mice. Phytomed. 16(6): 538-546.
Lin, C.M., Chen, C.S., Chen, C.T., Liang, Y.C., dan Lin, J.K. (2002). Molecular
Modeling Of Flavonoids that Inhibits Xanthine Oxidase. Biochemical and
Biophysical Research Communications. 294(2002): 167-172.
Mazzali, M., Hughes, J., Kim, Y.G., Jefferson, J., Kang, D.H., Gordon, K.L., Lan,
H.Y., Krvlighn, S. dan Johnson, R.J. (2001). Elevated uric acid increases
blood pressure in the rats by a novel crystal independent mechanism.
Hypertension. 38(5): 1101-1106.
Muhtadi, Suhendi, A., Nurcahyanti, W., Sutrisna, E.M. (2012). Potensi Daun
Salam (Syzigium polyanthum Walp.) dan Biji Jinten Hitam (Nigella sativa
Linn) Sebagai Kandidat Obat Herbal Terstandar Asam Urat. Pharmacon
13(1): 30-36.
Murray, K.R., Granner, K.D., Rodwell, W.V. (2003). Biokimia Harper . edisi 27.
Jakarta: EGC.
Price, S.A., dan Wilson, L.M. (2005). Patofisiologi: Konsep klinis konsep-konsep
penyakit. Edisi 6. Jakarta: EGC.
Ritschel, W.A. (1974). Laboratory Manual of Biopharmaceutics
Pharmacokinetics. Drug Intelligence Publication.
and
Shamley, D. (2005). Pathophysiology an Essential Text for the Allied Health
Professions, Elsevier Limited,USA.
Simarmata, V.B.C., Saragih, A., Bahri, S. (2012). Uji Efek Penurunan Kadar Asam
Urat Dari Ekstrak Etanol Daun Sidaguri (Sida rhombifolia l.) Pada Mencit
Jantan. Journal of Pharmaceutics and Pharmacology. 1 (1): 21-28.
Sugianto, I.S., Subandi., dan Muntolib. (2012). Uji fitokimia ekstrak pegagan
(centella asiatica) dan buah sirsak (annona muricata l.) Serta potensinya
sebagai inhibitor enzim xantin oksidase. Malang : FMIPA Universitas
Malang.
Umameswari, M. (2013). Virtual Screening Analysis and In-vitro Xanthine
Oxidase Inhibitory Activity of Some Commercially Available Flavonoids.
Iran J Pharm Res. 12(3): 317–323.
37
Universitas Sumatera Utara
Watanabe, S., Kimura, Y., Shindo, K. dan Fukui, T. (2006). Effect of Human
Placenta Extract on Potassium Oxonate-Induced Elevation of Blood Uric
Acid Concentration. Journal of Health Science. 52(6): 738-742.
Wisesa, I.B.N., Suastika, K. (2009). Hubungan Antara Konsentrasi Asam Urat
Serum Dengan Resistensi Insulin Pada Penduduk Suku Bali Asli Di Dusun
Tenganan Pegrisingan Karangasem. J Penyakit Dalam. 2(10): 110-122.
38
Universitas Sumatera Utara
Abdulla, M.A., AL-Bayaty, F.H., Younis L.T., and Abu H.M.I. (2010). Anti-ulcer
activity of Centella asiatica leaf extract against ethanol-induced gastric
mucosal injury in rats. Journal of Medicinal Plants Research. 4(13): 12531259.
Babykutty, S., Padikkala, J., Sathiadevan, P.P., Vijayakurup, V., Azis TKA.,
Srinivas, P., Gopala, S. (2009). Apoptosis induction of Centella asiatica on
human breast cancer cells. African J. Trad. Compliment Alternat, Med. 6(1):
9-16.
Bourne, R.H., dan Zastrow, V.M. (2001). Reseptor dan Farmakodinamika Obat.
Dalam Farmakologi Dasar dan Klinik. Edisi I. Jakarta: Salemba Medika.
BPOM RI. (2010). Serial Data Ilmiah Terkini Tumbuhan Obat; Pegagan (Centella
asiatica (L.) Urban). Jakarta: Direktorat Obat Asli Indonesia
Bradwejn, J., Zhou, Y., Koszycki, D.,Shlik, J. (2000). A double blind, placebocontrolled study on the effects of gotu kola (Centella asiatica) on acoustic
startle response in healthy subject. J.Clin Psychopharmacol. 20(6): 680.
Cesarone, M.R., Incandela, L., De Sanctis, M.T., Belcaro, G., Bavera, P., Bucci,
M., Ippolito, E. (2001). Evaluation of treatment of diabetic microangiopathy
with total triterpenic fraction of Centella asiatica: A clinical prospective
randomized trial with a microcirculatory model. Angiol. 52(2): 49-54.
Depkes RI. (1977). Materia Medika Indonesia . Jilid I. Jakarta: Departemen
Kesehatan RI.
Depkes RI. (1995). Materia Medika Indonesia . Jilid VI. Jakarta: Departemen
Kesehatan Republik Indonesia.
Depkes RI. (2000). Parameter Standar Umum Ekstrak Tumbuhan Obat. Jakarta:
Departemen Kesehatan.
Ditjen POM. (1979). Farmakope Indonesia . Edisi III. Jakarta: Departemen
Kesehatan Republik Indonesia.
Ditjen POM. (1995). Farmakope Indonesia . Edisi IV. Jakarta: Departemen
Kesehatan Republik Indonesia.
Ernest, M.E., Clark, E.C. dan Hawkins, D.W. (2008). Dalam: Dipiro, J.T., Talbert,
R.L., Yee, G.C., Matzke, G.R., Wells, B.G., dan Posey, L.M.
Pharmacoteraphy; A pathophysiologic Approach. Seventh edition (2008).
USA: The McGraw-Hill Companies.
35
Universitas Sumatera Utara
Farnsworth, N.R. (1966). Biological and Phytochemical Screening of Plants.
Journal of Pharmaceutical Sciences.
Gaw, A., Murphy, M.J. Robert, O’reilly, C.D., Stewart, M.J. dan Stepherd, J.
(2011). Biokimia Klinis: Teks Bergambar. Edisi ke-4. Diterjemahkan oleh:
dr.Albertus Agung Mahode dan July Manurung. Jakarta: EGC.
Gnanappragasama, A., Ebenezar, K.K., Sathish, V., Govindarajub, P., Devaki, T.
(2004). Protective effect of Centella asiatica on antioxidant tissue defense
system against adriamycin induced cardiomyopathy in rats. Life Sciences.
76(2): 585-597.
Gnanapragasama, A., Yogeeta, S., Subhashini, R., Ebenezar, K.K., Sathish, V.,
Devaki, T. (2007). Adriamycin induced myocardial failure in rats:
Protective role of Centella asiatica. Molecular and Cellular Biochemistry.
294(1): 55-63.
Harborne, J.B. (1987). Metode Fitokimia Penuntun Cara Modern Menganalisis
Tumbuhan. Penerjemah : Kokasih Padmawinata dan Iwang Soediro. Edisi
Ketiga. Bandung: ITB Press
Hidayat, R. (2009). Gout dan Hiperurisemia. Scientific Journal Of Pharmaceutical
Development and Medical Application. 22(1): 47-50.
Incandela, L., Cesarone, M.R., Cacchio, M., De Sanctis, M.T., Santavenere, C.,
D’Auro, M.G., Bucci, M., Belcaro, G. (2001). Total triterpenic fraction of
Centella asiatica in chronic venous insufiency and high-perfussion
microangiopathy. Angiol. 52(2): 13-15.
Jayanthirtha, M. (2004). Preliminary immunodulatory activities of methanol extract
of Elipta alba and Centella asiatica. Phytomed. 11(4): 361-365.
Jayshree, G., Kurup, M.G., Sudars, W.S., Jacob, V.B. (2003). Anti-oxidant activity
of Centella asiatica on lymphoma-bearing mice. Fitoterapia . 74(5): 431434.
Katzung, B.G. (2002). Farmakologi: Dasar dan Klinik. Jilid 3. Diterjemahkan
oleh: Bagian Farmakologi Fakultas Kedokteran UNAIR. Jakarta: Salemba
Medika
Kristiani, R.D., Rahayu, D. dan Subarnas, A. (2013). Aktivitas Antihiperurisemia
Ekstrak Etanol Akar Pakis Tangkur (Polypodium feei) Pada Mencit Jantan.
Bionatura-Jurnal Ilmu-Ilmu Hayati dan Fisik. ISSN 1411-0903. 15(3): 174177.
Kumar, A., Dogra, S., Prakash, A. (2009). Neuroprotective effects of Centella
asiatica against intracerebroventricular colchicines-induced cognitive
impairment and oxidative stress. Intern J. Alzaimer’s Dis. 23(4): 25-28.
36
Universitas Sumatera Utara
Laurance, B., Keith, P., Donald, B., dan Lain, B. (2008). Goodman and Gildman’s
Manual of Farmacology and Therapeutics. Boston: McGraw Hill.
Li, H., Gong, X., Zhang, L., Zhang, Z., Lu, F., Zhou, Q., Chen, J., Wan, J. (2009).
Madecassoside attenuate inflammatory response on collagen-induced
arthritis in DBA/1mice. Phytomed. 16(6): 538-546.
Lin, C.M., Chen, C.S., Chen, C.T., Liang, Y.C., dan Lin, J.K. (2002). Molecular
Modeling Of Flavonoids that Inhibits Xanthine Oxidase. Biochemical and
Biophysical Research Communications. 294(2002): 167-172.
Mazzali, M., Hughes, J., Kim, Y.G., Jefferson, J., Kang, D.H., Gordon, K.L., Lan,
H.Y., Krvlighn, S. dan Johnson, R.J. (2001). Elevated uric acid increases
blood pressure in the rats by a novel crystal independent mechanism.
Hypertension. 38(5): 1101-1106.
Muhtadi, Suhendi, A., Nurcahyanti, W., Sutrisna, E.M. (2012). Potensi Daun
Salam (Syzigium polyanthum Walp.) dan Biji Jinten Hitam (Nigella sativa
Linn) Sebagai Kandidat Obat Herbal Terstandar Asam Urat. Pharmacon
13(1): 30-36.
Murray, K.R., Granner, K.D., Rodwell, W.V. (2003). Biokimia Harper . edisi 27.
Jakarta: EGC.
Price, S.A., dan Wilson, L.M. (2005). Patofisiologi: Konsep klinis konsep-konsep
penyakit. Edisi 6. Jakarta: EGC.
Ritschel, W.A. (1974). Laboratory Manual of Biopharmaceutics
Pharmacokinetics. Drug Intelligence Publication.
and
Shamley, D. (2005). Pathophysiology an Essential Text for the Allied Health
Professions, Elsevier Limited,USA.
Simarmata, V.B.C., Saragih, A., Bahri, S. (2012). Uji Efek Penurunan Kadar Asam
Urat Dari Ekstrak Etanol Daun Sidaguri (Sida rhombifolia l.) Pada Mencit
Jantan. Journal of Pharmaceutics and Pharmacology. 1 (1): 21-28.
Sugianto, I.S., Subandi., dan Muntolib. (2012). Uji fitokimia ekstrak pegagan
(centella asiatica) dan buah sirsak (annona muricata l.) Serta potensinya
sebagai inhibitor enzim xantin oksidase. Malang : FMIPA Universitas
Malang.
Umameswari, M. (2013). Virtual Screening Analysis and In-vitro Xanthine
Oxidase Inhibitory Activity of Some Commercially Available Flavonoids.
Iran J Pharm Res. 12(3): 317–323.
37
Universitas Sumatera Utara
Watanabe, S., Kimura, Y., Shindo, K. dan Fukui, T. (2006). Effect of Human
Placenta Extract on Potassium Oxonate-Induced Elevation of Blood Uric
Acid Concentration. Journal of Health Science. 52(6): 738-742.
Wisesa, I.B.N., Suastika, K. (2009). Hubungan Antara Konsentrasi Asam Urat
Serum Dengan Resistensi Insulin Pada Penduduk Suku Bali Asli Di Dusun
Tenganan Pegrisingan Karangasem. J Penyakit Dalam. 2(10): 110-122.
38
Universitas Sumatera Utara